Clinical trials: Ovarian Hyperstimulation
No Condition
Comparison of Clinical Outcomes Between IVM and Minimal Stimulation IVF in Patients With PCOS
Polycystic ovarian syndrome (PCOS) is most common endocrinologic disease in women of reproductive age with incidence of 6.6 ~ 8%.
- Trial name
- NCT03134482
- Testing
- IVM, Minimal stimulation IVF
- Where
- 2 sites in South Korea
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- CHA University
Infertility, Sterility
Real-world Evidence on Follitropin Delta Individual Dosing
As part of the in vitro fertilisation treatment, ovarian stimulation is routinely performed. For this purpose, FSH preparations are used.
- Trial name
- NCT05173597
- Testing
- Follitropin delta
- Where
- Germany
- Volunteers
- 850 people
- Sponsor
- University of Luebeck
Ovarian Hyperstimulation Syndrome, Pregnancy Related
Freeze All Strategy Versus Fresh Embryo Transfer After GnRH Analogue Trigger
Ovarian hyperstimulation syndrome (OHSS) is one of the most dangerous complications of assisted reproduction technology (ART), described in approximatively 3 to 10% of stimulation cycles although an underestimation of the real…
- Trial name
- NCT05362734
- Testing
- obstetric outcomes after fresh versus cryopreserved embryo transfer
- Volunteers
- 1,396 people
- Sponsor
- Istituto Clinico Humanitas
PCOS, OHSS
Use of Degarelix in Controlled Ovarian Hyperstimulation (COH) Protocol for Women With PoliCystic Ovarian Syndrome (PCOS)
In this study the effectiveness of degarelix, a long acting GnRH antagonist administered in a unique administration of 20 mg the first day of menstrual cycle, to prevent ovarian hyperstimulation syndrome (OHSS) in PCOS women at…
- Conditions
- PCOS, OHSS, INFERTILITY
- Trial name
- NCT01709942
- Testing
- degarelix (long acting GnRH antagonist), cetrorelix 0.25mg
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Centre for Endocrinology and Reproductive Medicine, Italy
Fibrin Blood Clot, Infertility, Female
Ovarian Hyperstimulation and Fibrin Clot Properties.
The impact evaluation of ovarian hyperstimulation on coagulation and fibrinolysis in infertile women. Comparative analysis between different ovarian stimulation protocols on thrombin formation and efficiency of fibrinolysis in…
- Conditions
- Fibrin Blood Clot, Infertility, Female, Endometriosis
- Trial name
- NCT04166825
- Testing
- fibrin clot properties
- Where
- Poland
- Volunteers
- 300 people
- Sponsor
- Jagiellonian University
Ovarian Hyperstimulation Syndrome
Double GnRH Antagonist Daily Dose in Hyperresponding IVF/ICSI Cycles May Prevent the OHSS
The possibility to prevent the early ovarian hyperstimulation syndrome (OHSS) by doubling the daily dose of GnRH-antagonist in women stimulated with the antagonist protocol who are at risk for OHSS was evaluated.
- Trial name
- NCT01477970
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Iakentro Fertility Centre
Ovarian Hyperstimulation Syndrome
Ovarian Hyperstimulation Syndrome Using Calcium Infusion
the incidence of OHSS and clinical outcomes after calcium IV infusion in high-risk women undergoing ART
- Trial name
- NCT05198128
- Testing
- Calcium intravenous infsuion, 0.9 % saline
- Volunteers
- 200 people
- Sponsor
- Al-Azhar University
Premature Ovarian Failure (POF), Incipient Ovarian Failure
Pheno- & Genotyping POF (WHO III)
This study focuses on the phenotyping and genotyping of women with hypergonadotropic ovarian dysfunction (WHO III status).
- Conditions
- Premature Ovarian Failure (POF), Incipient Ovarian Failure, Poor Response After Ovarian Hyperstimulation, Early Menopause
- Trial name
- NCT01411644
- Where
- Netherlands
- Volunteers
- 650 people
- Sponsor
- UMC Utrecht
Complications Associated With Artificial Fertilization, Disorder of Endocrine Ovary
Cabergoline and Hydroxyethyl Starch in Ovarian Hyperstimulation Syndrome Prevention
The purpose of this study is to assess whether, in GnRH agonist in vitro fertilization (IVF) cycles, where there is a risk of ovarian hyperstimulation syndrome (OHSS), the addition of cabergoline to the hydroxyethyl starch…
- Trial name
- NCT01530490
- Testing
- Cabergoline and Hydroxyethyl Starch, Hydroxyethyl Starch
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hospital de Cruces
Male Infertility, Female Infertility
'SPRING'-Study: "Subfertility Guidelines: Patient Related Implementation in the Netherlands Among Gynaecologists"
The purpose of this study is to compare two different strategies to implement the existing Guideline programme on Subfertility, as issued by the Dutch Society of Obstetrics and Gynaecology (NVOG).
- Conditions
- Male Infertility, Female Infertility, Ovarian Hyperstimulation Syndrome, Premature Ovarian Failure
- Trial name
- NCT00119925
- Testing
- patient education, professional audit and feedback (guideline adherence), professional education (communication/shared decision making)
- Where
- 16 sites in Netherlands
- Volunteers
- 5,200 people
- Sponsor
- Radboud University Medical Center
Female Subjects Undergoing Controlled Ovarian Hyperstimulation
Serum FSH Levels During Controlled Ovarian Stimulation
Follicle-stimulating hormone (FSH) plays a central role in controlled ovarian stimulation (COS) during in vitro fertilization (IVF) cycles.
- Trial name
- NCT07460674
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Infertility, Female
Exploratory Study Assessing Synchronisation of Egg Sacs With Degarelix
The main purpose of this clinical research study is to investigate if degarelix can synchronise the growth of the egg sacs in the ovaries and if degarelix has any effect on the lining of the womb.
- Trial name
- NCT00434122
- Testing
- Degarelix mid-luteal, 2.5 mg
- Where
- 4 sites in Belgium, Czechia and 1 more
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Ferring Pharmaceuticals
OHSS
Cabergoline Versus Calcium Gluconate Infusion in the Prevention of Ovarian Hyperstimulation Syndrome
The aim of this study is to compare the efficacy of calcium gluconate infusion versus cabergoline in the prevention of ovarian hyperstimulation syndrome (OHSS) in patients pretreated with GnRH agonist long protocol who are at…
- Trial name
- NCT02875587
- Testing
- Cabergoline, Calcium gluconate
- Where
- 2 sites in Egypt
- Volunteers
- 170 people
- Sponsor
- Aljazeera Hospital
Ovarian Hyperstimulation Syndrome, Frozen-thawed Embryo Transfers
Association Between Live Birth Rate and Serum Progesterone During Hormonal Replacement Therapy
Nowadays, frozen-thawed embryo transfers (FET) are expending. This practice avoids risk of ovarian hyperstimulation syndrome (OHSS), as well as allowing better synchronization between endometrium and embryo, which is fundamental…
- Trial name
- PROGEVOL (NCT05588635)
- Testing
- Identification of predictive factors
- Where
- France
- Volunteers
- 168 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Polycystic Ovarian Syndrome, Ovarian Hyperstimulation Syndrome
Long Acting GnRH Antagonist in PCOS Women Undergoing IVF
PCOS is a common endocrinopathy affecting 5-10% of women in their reproductive age characterized by hyperandrogenism, chronic anovulation and polycystic ovaries.
- Conditions
- Polycystic Ovarian Syndrome, Ovarian Hyperstimulation Syndrome, Invitro Fertilization
- Trial name
- NCT02084940
- Testing
- GnRH antagonist depot Degarelix
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Bioroma
Ovarian Hyperstimulation Syndrome
Endometrial Receptivity After GnRH Agonist Triggering
Conventional luteal phase support after human chorionic gonadotrophin (hCG) triggering in women undergoing in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) provides adequate pregnancy rates and live birth rates…
- Trial name
- ERAMAD (NCT01500863)
- Testing
- hCG, triptorelin, Triptorelin, estradiol valerate, micronized vaginal progesterone
- Where
- Spain
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- IVI Madrid
Ovarian Hyperstimulation Syndrome
Study of Serum Levels of Oxidative Stress Markers in Ovarian Hyperstimulation Patients
The aim of the study is to determine serum oxidative stress status by ischemia modified albumin (IMA), total antioxidant capacity (TAC), total oxidative capacity (TOS), oxidative stress capacity (OSI), and serum malondialdehyde…
- Trial name
- NCT02202278
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people
- Sponsor
- Karadeniz Technical University
Infertility
Gonadotropin-releasing Hormone Antagonist on Triggering Day: A Randomized Controlled Study
Gonadotropin-releasing hormone (GnRH) antagonists have been widely used for the prevention of premature luteinizing hormone (LH) surges during controlled ovarian hyperstimulation (COH) for in vitro fertilization and embryo…
- Trial name
- NCT00571870
- Testing
- cetrorelix acetate
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Seoul National University Bundang Hospital
Infertility
NATural Ovarian Stimulation
To overcome unsuitable effects of controlled ovarian hyperstimulation (COH )while maintaining large oocyte availability, investigators elaborated an innovative protocol (NATural Ovarian Stimulation) that dissociates E2 production…
- Trial name
- NATOS (NCT02892942)
- Testing
- Gonal-F®, Cetrotide®
- Where
- France
- Volunteers
- 129 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris