Clinical trials: Ovarian Mass, active
Ovarian Cancer, Ovarian Tumor
AI Analysis of CT Scans to Classify Ovarian Tumours as Benign, Borderline or Malignant Before Surgery
The goal of this observational study is to learn if a computer program can tell what type of ovarian tumour a person has from a CT scan taken before surgery. The program uses artificial intelligence (AI).
- Conditions
- Ovarian Cancer, Ovarian Tumor, Borderline Ovarian Tumor
- Trial name
- OvaClass (NCT07883551)
- Where
- 7 sites in Belgium, Netherlands
- Volunteers
- 1,300 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Hormone Receptor-Positive Breast Cancer
Estradiol Levels According to Body Mass Index in Premenopausal Patients With Breast Cancer
his prospective observational study will evaluate whether body mass index (BMI) is associated with serum estradiol levels in premenopausal women with hormone receptor-positive breast cancer.
- Trial name
- SIMPEC-E2 (NCT07833501)
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- D'Or Institute for Research and Education
Pancreas Cancer, Hepatocellular Carcinoma
Analysis of Breath Volatile Organic Compounds Using Mass Spectrometry
The purpose of this clinical trial is to evaluate whether volatile organic compound (VOC) signatures detected in the breath of patients with cancer can serve as a potential screening tool for the early detection of cancer.
- Conditions
- Pancreas Cancer, Hepatocellular Carcinoma, Lung Cancer, Ovarian Cancer
- Trial name
- NCT07732686
- Testing
- Proton Transfer Reaction Mass Spectrometry Analysis
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Ovarian Cancer
Transcriptional Map of Ovarian Cancer at the Single Cell Level
In 2020, epithelial ovarian cancer (EOC) accounts for 313,959 new cases and 207,252 deaths worldwide. The standardized 5-year net survival of a woman with EOC is 44% for cases diagnosed between 2005-2010.
- Trial name
- Ova-seq (NCT05030805)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Strasbourg, France
Adenopathy, Uterine Fibroids
A Clinical Study on the Feasibility and Safety of Abdominal Endoscopic Single-port Surgery System to Assist Gynecological Day Surgery
In this study, a prospective study is used to select patients who will undergo intra-abdominal endoscopic single-port surgery system for benign gynecological diseases from February 2025 to December 2026 in the Second Affiliated…
- Conditions
- Adenopathy, Uterine Fibroids, Ovarian Cysts, Adnexal Mass
- Trial name
- NCT06828419
- Testing
- Domestic single-port laparoscopic surgery system
- Where
- China
- Volunteers
- 63 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Polycystic Ovarian Syndrome Females
Effects of Senobi Exercise & Aerobic Exercises in Polycystic Ovarian Syndrome
One of the most prevalent endocrine system conditions affecting women of reproductive age is polycystic ovary syndrome (PCOS), also known as hyperandrogenic anovulation (HA) or Stein-Leventhal syndrome.
- Trial name
- CESAEBMIFQPCOS (NCT07328048)
- Testing
- Senobi exercises with aerobics exercises, aerobic exercises
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Ovarian Neoplasms
A Diagnostic Test to Evaluate Cancer Risk Before Surgery in Women With an Ovarian Mass
Ovarian cancer is a serious health risk with the highest death rate among gynecological cancers. Unfortunately, it's only possible to definitively diagnose ovarian cancer after surgery, as there are no reliable tests to determine…
- Trial name
- NCT06566716
- Testing
- CleoDX ovarian cancer test
- Where
- 19 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Cleo Diagnostics Ltd
Body Mass Index 25 or Greater, BRCA1 Gene Mutation
Energy Balance Interventions in Increasing Physical Activity in Breast Cancer Gene Positive Patients, Lynch Syndrome-Positive Patients, CLL Survivors or High-Risk Family Members
This pilot clinical trial studies different types of energy balance interventions to see how well they work in increasing the physical activity levels of breast cancer gene-positive patients, Lynch syndrome-positive patients…
- Conditions
- Body Mass Index 25 or Greater, BRCA1 Gene Mutation, BRCA2 Gene Mutation, Breast Carcinoma
- Trial name
- NCT02194387
- Testing
- Dietary Intervention, Internet-Based Intervention, Laboratory Biomarker Analysis
- Where
- United States
- Volunteers
- 337 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Ovarian Cancer, Ovarian Cyst Benign
Evaluation of Salivary RNAs in the Presence of an Adnexal Mass of Ovarian Origin
OVAmiARN is a multicentre, prospective, longitudinal, non-interventional, observational study carried out in 8 obstetrics and gynecology departments in France; in order to describe the evolution of salivary miRNA expression…
- Conditions
- Ovarian Cancer, Ovarian Cyst Benign, Borderline Ovarian Cancer
- Trial name
- OVAmiARN (NCT05514028)
- Testing
- Salivary samples
- Where
- 21 sites in France, Switzerland and 1 more
- Volunteers
- 746 people
- Sponsor
- ZIWIG
Obesity, Colon Cancer
Proteomic Analysis of Patients Undergoing Bariatric Surgery
The expression of proteins in the blood of obese individuals is different from the expression of proteins in healthy individuals, and is also different in individuals after bariatric surgery.
- Conditions
- Obesity, Colon Cancer, Thyroid Cancer, Esophageal Cancer
- Trial name
- NCT06787807
- Testing
- bariatric surgery
- Where
- Brazil
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Ovarian Neoplasms, Adnexal Mass
Research and Application of Ultrasonic Intelligent Diagnosis System for Ovarian Mass
Research on automatic detection of ovarian mass and intelligent auxiliary diagnosis system based on multimodal ultrasound images.
- Trial name
- NCT06528236
- Testing
- Artificial intelligence model
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Zhejiang Provincial People's Hospital
Endometriosis, Fibroids
Impact of Educational Videos on Pre-operative Anxiety
The goal of this clinical trial is to learn if educational videos can reduce pre-operative anxiety in patients undergoing minimally invasive gynecologic surgery.
- Conditions
- Endometriosis, Fibroids, Adenomyosis, Pelvic Pain
- Trial name
- NCT07740759
- Testing
- educational video
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- UConn Health
Ovarian Mass
Concordance Between Radiologic Laparoscopic and Laparotomic Evaluation for Complete Cytoreduction of Ovarian Masses
Ovarian mass occur in women of all ages, and their etiology and frequency range age accordingly. The ovarian mass may come from functional or physiological changes, inflammatory processes, endometriosis, benign and malignant…
- Trial name
- NCT07416435
- Volunteers
- 28 people
- Sponsor
- Assiut University
Sonography, Ovarian Mass
Sonographic Evaluation of Ovarian Masses by ORADS System
This observational study will evaluate how well an ultrasound scoring system called O-RADS can distinguish between benign (non-cancerous) and malignant (cancerous) ovarian masses in women aged 18 to 70 years.
- Trial name
- NCT07289126
- Volunteers
- 80 people
- Sponsor
- Assiut University
Obesity & Overweight, Diabetes Mellitus, Type 2
Chinese Overweight/Obesity Cohort: Metabolic & Comorbidity Risks
This is a nationwide, multi-center, long-term follow-up study of overweight and obese adults in China. The study aims to recruit approximately 26,000 participants across 39 hospitals to better understand how body weight affects…
- Conditions
- Obesity & Overweight, Diabetes Mellitus, Type 2, Hypertension, Non-alcoholic Fatty Liver Disease (MASLD)
- Trial name
- NCT07884903
- Testing
- No intervention; observational assessment only
- Where
- China
- Volunteers
- 25,974 people
- Sponsor
- Shanxi Bethune Hospital
Polycystic Ovary Syndrome
The Effect of Lifestyle Program Women With PCOS
Polycystic Ovary Syndrome (PCOS) is a common hormonal condition affecting women of reproductive age. In addition to physical symptoms such as irregular menstruation, hormonal changes, and changes in body weight, women with PCOS…
- Trial name
- PCOS (NCT07880366)
- Testing
- Lifestyle Modification Program (LMP)
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Government College University Faisalabad
Ovarian Mass, Adnexal Mass
An AI-Assisted Agentic System for Ultrasound Scanning and Diagnosis of Ovarian Lesions
Investigators developed an interactive agentic system designed to guide newly qualified sonographers in ovarian lesion scanning and improve their scanning quality and diagnostic performance toward expert-level standards.
- Trial name
- NCT07801209
- Testing
- non-AI assisted and then AI assisted, AI assisted and then non-AI assisted
- Where
- 2 sites in China
- Volunteers
- 250 people
- Sponsor
- Women's Hospital School Of Medicine Zhejiang University
Ovarian Neoplasms, Ovarian Cancer
Improved Diagnosis of Ovarian Cancer
After implementation of systematic image description of adnexal masses, we aim to improve and evaluate our use of available imaging methods and biomarkers for classifying adnexal masses and distinguishing between benign and…
- Conditions
- Ovarian Neoplasms, Ovarian Cancer, Ovarian Cysts, Adnexal Mass
- Trial name
- NCT05842629
- Where
- Denmark
- Volunteers
- 1,700 people
- Sponsor
- University of Aarhus
Ovarian Cancer, Ovarian Mass
MIRRORS-FROZEN - Comparing Open Vs Robotic Surgery in the Management of Women With Complex Pelvic Adnexal Masses ≤ 8cm.
Adnexal masses are growths that can form in the ovaries or fallopian tubes for different reasons, such as hormonal changes, infection, or cancer.
- Conditions
- Ovarian Cancer, Ovarian Mass, Ovarian Cysts, Fallopian Tube Neoplasms
- Trial name
- MIRRORS-FROZEN (NCT06638593)
- Testing
- MIRRORS-FROZEN Protocol., Standard open surgery
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- Royal Surrey County Hospital NHS Foundation Trust
Chemotherapy-Induced Amenorrhea
Metabolism, Circadian Rhythms and Ovarian Function
Chemotherapy for cancer, due to its gonadotoxicity, can lead to impaired female fertility, resulting in the occurrence of transient or prolonged chemo-induced amenorrhea (CIA).
- Trial name
- METAB-OV (NCT05007834)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Lille