Clinical trials: Ovary Cyst
Hyperandrogenemia, Polycystic Ovary Syndrome (PCOS)
Assessment of the Sensitivity of the Hypothalamic GnRH Pulse Generator to Estradiol and Progesterone Inhibition
Girls with high levels of the male hormone testosterone often develop polycystic ovary syndrome (PCOS) as adults. Women with PCOS often have irregular menstrual periods, excess facial and body hair, and weight gain.
- Trial name
- NCT01425541
- Testing
- estrace, Progesterone
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Virginia
Ovarian Cysts
Comparison Between Electrosurgical Energy and Hemostatic Sealants on Hemostasis in Laparoscopic Ovarian Cystectomy
The aim of this study is to compare between the effect of using electrosurgical energy and hemostatic sealant for hemostasis in laparoscopic cystectomy for ovarian cysts.
- Trial name
- NCT06913335
- Testing
- laparoscopic ovarian cystectomy using hemostatic sealant, laparoscopic ovarian cystectomy using electrosurgical energy
- Where
- Egypt
- Volunteers
- 58 people
- Sponsor
- Kafrelsheikh University
Polycystic Ovary Syndrome
Dose Adjusted vs. Fixed Dose Unilateral Laparoscopic Ovarian Drilling in PCOS Patients
Polycystic ovary syndrome (PCOS) is a common endocrine disorder and a leading cause of infertility in women of reproductive age affecting up to 20% of them.
- Trial name
- NCT04021940
- Testing
- ULOD
- Volunteers
- 128 people
- Sponsor
- Hatem AbuHashim
Pregnancy, Polycystic Ovary Syndrome
Metformin and Folate in Pregnant Polycystic Ovary Syndrome(PCOS) Women
A more recent prospective nonrandomized placebo-controlled double-blind clinical study demonstrated that metformin exerts a slight but significant deleterious effect on serum homocysteine (Hcy) levels in patients with PCOS, and…
- Trial name
- NCT01115140
- Testing
- Metformin plus folic acid
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Magna Graecia
Polycystic Ovary Syndrome
Effects of Metformin vs Oral Contraceptives on CV Risk Markers in PCOS
Cardiovascular risk factors cluster in hyperandrogenic women - including those presenting with the polycystic ovary syndrome - in association with insulin resistance, obesity, and other metabolic disorders.
- Trial name
- NCT00428311
- Testing
- Metformin, Ethynyl-estradiol plus cyproterone acetate
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Ramon y Cajal
Ovarian Cyst
Effects of Adrenergic Drugs on the Fluid Balance During Surgery
The aim this study was to examine to what degree the slow turnover of lactated Ringer's solution during anesthesia and surgery can be prevented by infusing esmolol (a ß1-receptor blocker) or phenylephrine in patients undergoing…
- Trial name
- NCT01431612
- Testing
- Esmolol administration, Phenylephrine infusion, Lactated Ringer´s solution
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Sodertalje Hospital
Polycystic Ovary Syndrome
Metformin and Oral Contraceptives in PCOS
Background: PCOS is a common condition with a prevalence of 5-8 % in premenopausal women. More than 50% of PCOS patients are insulin resistant and have a diabetes risk 5-8 times higher than age- and weight-matched controls.
- Trial name
- NCT00451568
- Testing
- Metformin, Desorelle
- Where
- Denmark
- Volunteers
- 90 people
- Sponsor
- Odense University Hospital
Polycystic Ovarian Syndrome
Letrozole Combined With Gonadotropins (Gn) for Ovarian Stimulation Undergoing in Vitro Fertilization/Intracytoplasmic Sperm Injection (IVF/ICSI) in Patients With Polycystic Ovary Syndrome (PCOS)
The purpose of this study is to determine whether letrozole combined with gonadotropins are effective in the ovarian hyperstimulating for IVF/ICSI in patients with PCOS.
- Trial name
- NCT00894608
- Testing
- letrozole + gonadotropins, GnRHa + gonadotropins
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Yunyang Medical College
Polycystic Ovary Syndrome
Study of Brain Function in Women With Insulin Resistant Polycystic Ovary Syndrome
The purpose of this study is to evaluate the effects of insulin resistance on brain function in women with Polycystic Ovary Syndrome (PCOS).
- Trial name
- NCT00670800
- Testing
- Metformin
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Michigan
PCOS
PCOS and Brain Health
The purpose of this study is to determine how polycystic ovary syndrome (PCOS) impacts overall brain health, such as cerebral blood flow (CBF), brain structure and connectivity, and cognitive performance.
- Trial name
- NCT07727512
- Testing
- MRI Visit, Laboratory Visit
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Polycystic Ovary Syndrome, Insulin Resistance
The Effect of Acupuncture on Insulin Sensitivity Polycystic Ovary Syndrome
Hyperinsulinemia and insulin resistance play a key role in the pathogenesis of polycystic ovary syndrome (PCOS). Insulin resistance is significantly associated with the long-term risks of metabolic syndrome and cardiovascular…
- Trial name
- NCT02026323
- Testing
- acupuncture
- Where
- China
- Volunteers
- 112 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Polycystic Ovary Syndrome
Comparison of Probiotics, Metformin & Their Combination Therapy in the Treatment of PCOS
Polycystic ovary syndrome (PCOS) is a common gynecological state worldwide characterized by numerous small cysts in the ovaries mainly due to the imbalance of endocrine hormones in premenopausal women.
- Trial name
- NCT04009603
- Testing
- Probiotic Agent, Metformin
- Where
- Pakistan
- Volunteers
- 78 people
- Sponsor
- Ziauddin University
Polycystic Ovary Syndrome, Reproductive Medicine
Interest of Myo-inositol Supplementation in Women With Polycystic Ovarian Syndrome
The main objective will be to check if MyoInositol (MYO) reduces the total resistance rate to Clomiphene Citrate (CC). For this, our study will be controlled, randomized and double blinded.
- Trial name
- MYOPK (NCT03059173)
- Testing
- Myo-Inositol + Levomefolic acid, Clomiphene Citrate
- Where
- France
- Volunteers
- 276 people
- Sponsor
- University Hospital, Lille
Polycystic Ovarian Syndrome (PCOS)
Polycystic Ovarian Syndrome (PCOS) Biomarker Evaluation Study
The purpose of the study is to validate recently identified biomarkers for the identification of PCOS in adolecent and young adult women.
- Trial name
- PHOEBE (NCT06642831)
- Where
- Germany
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- University Hospital Erlangen
Polycystic Ovary Syndrome
Effect of NMN (Nicotinamide Mononucleotide) on Polycystic Ovary Syndrome
The purpose of the study is to understand the effect of Nicotinamide mononucleotide (NMN) on patients with polycystic ovary syndrome.
- Trial name
- NMN (NCT05305677)
- Testing
- NMN intervention
- Where
- China
- Volunteers
- 88 people
- Sponsor
- Peking University Third Hospital
Polycystic Ovary Syndrome
Intermittent Fasting Diet Versus Resistive Exercise Program on Insulin Resistance in Obese Women With P.C.O.S
This study will be carried out in an attempt to know which is more effective, Intermittent fasting diet or resistive exercise program on insulin resistance in obese woman with polycystic ovarian syndrome.
- Trial name
- NCT06882291
- Testing
- Intermittent fasting diet, Resistive exercise program, Medical treatment
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Cairo University
Infertility
The Effect of Ethinyl Estradiol on Polycystic Ovary Syndrome Women Undergoing Intrauterine Insemination
According to the studies CC is successful at inducing ovulation in 50%-75% of cases, but only 30-40% becomes pregnant. The difference has been attributed to a negative action of clomifen citrate(CC) in the form of prolonged…
- Trial name
- NCT01219101
- Testing
- clomiphene citrate with ethinyl esteradiol, clomiphene citrate with plasebo
- Where
- Iran
- Volunteers
- 95 people
- Sponsor
- Royan Institute
Poly Cystic Ovary Syndrome
Efficacy of Dapagliflozin Versus Metformin in Polycystic Ovary Syndrome
In PCOS (Polycystic Ovary Syndrome), studies have found impaired incretin secretion and activity, particularly in overweight/obese individuals.
- Trial name
- NCT07810998
- Testing
- Metformin, Dapagliflozin (10mg Tab)
- Volunteers
- 60 people
- Sponsor
- Tanta University
Polycystic Ovary Syndrome
Plant Exosomes and Patients Diagnosed With Polycystic Ovary Syndrome (PCOS) 17
The purpose of this study is to see if substances contained in ginger or aloe plants, called exosomes, will treat and improve the condition polycystic ovary syndrome
- Trial name
- NCT03493984
- Testing
- Ginger exosomes, Aloe exosomes
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Louisville
Infertility, Polycystic Ovarian Syndrome
Use of Low Dose of HCG During Ovulation Induction With CC in Women With CC Resistant PCOS
The purpose of this study is to evaluate the effect of administration of low dose of human chorionic gonadotropin (HCG) after use of clomiphene citrate (CC) for induction of ovulation in infertile women having CC resistant…
- Trial name
- NCT02436226
- Testing
- Clomiphene citrate and Human chorionic gonadotropin (HCG), Clomiphene citrate
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Mohamed Sayed Abdelhafez
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