Clinical trials: Over the Age of 65
Diabetes Type 1
Transition of T1DM Patients Aged Over 65 Years Into AHCL (780G) Insulin Pump
Older people with diabetes have a higher risk for cognitive impairment and for physical disability whether this may be effected by an improvement in glucose indices is unknown.
- Trial name
- 780G65+ (NCT06207838)
- Testing
- MiniMed 780G system
- Where
- Poland
- Volunteers
- 30 people
- Sponsor
- Jagiellonian University
ELDRELY
Nutritional Status in Patients Over 65 Years of Age and Meal Presentation
The prevalence of undernutrition in hospitals is estimated between 30 and 40% and up to 50% in the elderly. The consequences of undernutrition are significant: complications, delayed healing, higher risk of infections, pressure…
- Trial name
- NUPOBA (NCT04696068)
- Testing
- Porcelain plates
- Volunteers
- 300 people
- Sponsor
- University Hospital, Caen
Inappropriate Prescribing, Implementation Science
Reduction of Low-value Prescribing Through Audit and Feedback
The objective is to estimate the effect attributable to a primary care pharmacist-led audit and feedback (AF) strategy compared to the currently used AF strategy as a management tool to evaluate healthcare performance focusing on…
- Conditions
- Inappropriate Prescribing, Implementation Science, Behavioral Sciences
- Trial name
- AFFAP (NCT07336550)
- Testing
- Usual AF, Facilitated AF
- Where
- Spain
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- Basque Health Service
Active Aging Individuals Aged 65 and Over, Aging
Italian Validation of the dNA Scale and Its Correlation With Neurocognitive Variables
The goal of this experimental multicentric intervention study is to validate, in Italian, the dynamic Neurocognitive Adaptation (dNA) Scale, which has already been validated in English, among a healthy elderly population (aged 65…
- Conditions
- Active Aging Individuals Aged 65 and Over, Aging, Mild Cognitive Impairment (MCI), Dementia
- Trial name
- NCT07533084
- Where
- 8 sites in Italy
- Volunteers
- 265 people, healthy volunteers welcome
- Sponsor
- Neuromed IRCCS
Hepatitis E
A Phase Ⅳ Clinical Trial of the Recombinant Hepatitis E Vaccine (Escherichia Coli)
This phase IV clinical study was designed to evaluate the safety and immunogenicity of the recombinant Hepatitis E vaccine(Hecolin®), manufactured by Xiamen Innovax Biotech CO., LTD., in healthy volunteers aged over 65 years of…
- Trial name
- NCT02417597
- Testing
- Recombinant Hepatitis E Vaccine (Escherichia Coli)
- Where
- China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Xiamen Innovax Biotech Co., Ltd
Non-Small Cell Lung Cancer
Study of Erlotinib With Docetaxel in Selected Non Small Cell Lung Cancer Patients in First Line Treatment
Study Rationale: There is increasing evidence that erlotinib improves overall survival in selected patients with stage IIIB-IV NSCLC.
- Trial name
- NCT00840125
- Testing
- erlotinib, docetaxel
- Where
- Israel
- Volunteers
- 4 people
- Sponsor
- Meir Medical Center
Muscle, Cognitive Functioning
This Study Investigates β-hydroxy-β-methylbutyrate (HMB) and 2-hydroxybenzylamine (2-HOBA), When Administered Either Individually or in Combination Contributes to an Increased Quality of Health, Specifically Improving Muscular Strength and Cognitive Functioning in Adults Over the Age of 65.
In this study, participants will be assigned to receive HMB, 2-HOBA, a combination of both, or a comparison supplement for a set period of time.
- Conditions
- Muscle, Cognitive Functioning, Geriatric, Ageing and Geriatric Health
- Trial name
- H2AGE (NCT07419633)
- Testing
- β-Hydroxy-β-methylbutyrate, 2-hydroxybenzylamine, β-Hydroxy-β-methylbutyrate and 2-hydroxybenzylamine
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Appetite, Food Intake
Effect of Sumac on Appetite and Food Intake
Sumac, is a spice that is widely used in Turkish, Iranian and Middle Eastern foods. In these regions, the fruit of sumac is used for seasoning or flavouring, as an appetizer and for souring food.
- Trial name
- NCT05534152
- Testing
- sumac
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Oxford Brookes University
Aged, 80 and Over, Resistance Training
Resistance-type Exercise Training in the Older Population
Background: Aging is associated with muscle mass and strength loss and "oldest" old people (≥85 y) are at a far greater risk of developing sarcopenia.
- Trial name
- RETO (NCT04999501)
- Testing
- Prolonged resistance-type exercise training
- Where
- Chile
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Universidad de La Frontera
Anemia
Trial To Evaluate the Efficacy of Oral Salsalate in the Treatment of Older Adults With Unexplained Anemia
The purpose of this study is to determine whether treatment of unexplained anemia in older adults and elevated inflammatory markers with oral salsalate can improve hemoglobin levels and improve physical activity and quality of…
- Trial name
- NCT01506726
- Testing
- Salsalate
- Where
- 12 sites in United States
- Volunteers
- 11 people
- Sponsor
- Harvey Jay Cohen
Individuals Over 65 Years of Age
Breath Meditation on the Older People
A decrease in physical activity during old age leads to a decline in quality of life and life satisfaction. Increased stress and anxiety levels during this period negatively affect individuals' mood and reduce their quality of…
- Trial name
- MEDITATION (NCT07263828)
- Testing
- breathing meditation
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Istanbul Aydın University
Fabry Disease, Aged 65 Years or Older
Study of the Quality of Life of Patients With Fabry Disease Aged 65 and Over With and Without Specific Treatment
Fabry disease is a rare genetic disorder affecting 1 in 10,000 individuals, leading to complications such as chronic pain, heart and kidney failure, and strokes, ultimately impacting life expectancy.
- Conditions
- Fabry Disease, Aged 65 Years or Older, Alpha Galactosidase A Deficiency, Galactosidase A Gene Mutation
- Trial name
- FABRY65 (NCT07277361)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Wladimir MAUHIN, Dr
Frailty, Frailty Syndrome
Prevalence, Determinants and Natural History of Frailty and Pre-frailty in Elderly People
Frailty syndrome (i.e. frailty) is a geriatric syndrome which relies on the reduction of multisystem reserve capacity. Frail people have a lower potential to respond to external stressors and various life incidents as well as…
- Conditions
- Frailty, Frailty Syndrome, Frail Elderly Syndrome, Fragility
- Trial name
- FRAILPOL (NCT04518423)
- Where
- Poland
- Volunteers
- 1,093 people, healthy volunteers welcome
- Sponsor
- The Opole University of Technology
Frail Elderly, Dual Task Exercises in Elderly People
FreeFrail Project: A Multicomponent Intervention for the Management of Frailty in Primary Care: A Randomized Controlled Trial
The primary aim is to assess the effectiveness of a multicomponent intervention including dual-task exercise in improving functionality and cognitive performance and in reducing frailty among community-dwelling adults aged ≥65…
- Conditions
- Frail Elderly, Dual Task Exercises in Elderly People, Exercise Training, Frailty
- Trial name
- NCT07205016
- Testing
- Dual task exercise, Otago exercise
- Volunteers
- 220 people
- Sponsor
- Universitat de Lleida
Influenza
Study on the Incidence of Influenza and Its Complications, in Subjects Aged 50 Years and Over Vaccinated With Fluarix™
A study to investigate the incidence of influenza and influenza-related complications, in adults between 50-64 years and elderly adults 65 years and over vaccinated with Fluarix™
- Trial name
- NCT00377611
- Testing
- Fluarix™
- Where
- 37 sites in United States, Germany and 2 more
- Volunteers
- 3,054 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Frailty Syndrome
The Effectiveness of Training Using Exergaming on Selected Physical and Psychological Parameters in a Population of Patients Over the Age of 65 Belonging to Specific Subgroups of the Frailty Syndrome
This study aims to evaluate the effects of a six-week exergaming-based training program on physical and psychological parameters in individuals aged 65 and older diagnosed with frailty or pre-frailty.
- Trial name
- FREX (NCT07036224)
- Testing
- Exergaming Training using Kinect sensor device
- Where
- Poland
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Influenza Vaccination, Immune Response
Effects of Lactobacillus Coryniformis CECT5711 on Immune Response to Influenza Vaccination in Adults Over 65.
The objective of the present study is to evaluate the capability of the probiotic strain Lactobacillus coryniformis K8 CECT5711 (Lc K8) to enhance the immune response to influenza vaccine in elderly and the effect on respiratory…
- Conditions
- Influenza Vaccination, Immune Response, Probiotics
- Trial name
- NCT03167593
- Testing
- Lactobacillus coryniformis K8 CECT5711
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Biosearch S.A.
Dance Therapy, Self Neglect
Dance and Movement Therapy Techniques in Elderly People
Aim: To investigate the effects of dance and movement therapy or walking interventions for elderly people aged 65 and over who are registered to the family health center located in the city center of Amasya, on the loneliness and…
- Conditions
- Dance Therapy, Self Neglect, Loneliness
- Trial name
- NCT05655455
- Testing
- walking group: 1.group, dance and movement therapy group: 2.group
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Amasya University
Healthy
Pharmacokinetics of Dipyridamole Administered as Aggrenox® (Dipyridamole Extended Release Plus Aspirin) Capsule Versus Dipyridamole Immediate Release Plus Aspirin Following Alteration of Stomach pH
Comparison of pharmacokinetics of dipyridamole administered as Aggrenox versus dipyridamole administered as the immediate release formulation plus aspirin, under conditions of reduced stomach acidity.
- Trial name
- NCT02251184
- Testing
- Aggrenox, Dipyridamole, Aspirin
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Telemedicine
Smartphone Applications to Improve Lifestyles in Olders Over 65 Years
This is a randomized controlled clinical trial performed in urban primary care centers in Salamanca (Spain). Its objective is to evaluate the effect of an intervention based on the use of new information and communication…
- Trial name
- EVIDENT-Age (NCT03574480)
- Testing
- Intervention (training in use of a Smartphone application), Control (Advice on healthy diet and physical activity recommendations)
- Where
- Spain
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Fundacion para la Investigacion y Formacion en Ciencias de la Salud