Clinical trials: Over the Age of 65, active
Sarcopenia in Elderly
The Study, Conducted With 54 Individuals Over the Age of 65, Aimed to Reveal the Advantages and Disadvantages of a Combined Exercise Program Compared to Otago Exercise Alone.
Falls are a leading cause of morbidity and mortality in older adults. Approximately one-third of individuals over 65 years of age fall each year, and 10-15% of these falls result in serious injury.
- Trial name
- OPEP-SARCOBAL (NCT07689903)
- Testing
- Proprioception Exercise, Exercise Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Inappropriate Prescribing, Implementation Science
Reduction of Low-value Prescribing Through Audit and Feedback
The objective is to estimate the effect attributable to a primary care pharmacist-led audit and feedback (AF) strategy compared to the currently used AF strategy as a management tool to evaluate healthcare performance focusing on…
- Conditions
- Inappropriate Prescribing, Implementation Science, Behavioral Sciences
- Trial name
- AFFAP (NCT07336550)
- Testing
- Usual AF, Facilitated AF
- Where
- Spain
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- Basque Health Service
Adapted Physical Activity
Effectiveness of Adapted Physical Activity Programs in Preventing Falls in People Aged Over 65
The objective of this study is to evaluate the effectiveness of Adapted Physical Activity (APA) programs offered by Sport-Health Centers (MSS) in reducing the risk of falls in the elderly.
- Trial name
- APA-SAFE (NCT06985719)
- Volunteers
- 50 people
- Sponsor
- Centre Médical Porte Verte
Asthma, Mild Asthma
A Study to Compare the Relative Potency of Salbutamol Administered Via Metered Dose Inhalers (MDI) Containing Propellants HFA-152a to HFA-134a in Mild Asthmatics Aged 18 to 65 Inclusive
The primary objectives of the study are: Part 1: to characterize the potency and variability of dose response on efficacy (Provocative concentration of methacholine causing at least a 20% fall in forced expiratory volume (FEV1)…
- Trial name
- NCT06433921
- Testing
- Salbutamol HFA-152a, Salbutamol HFA-134a
- Where
- United Kingdom
- Volunteers
- 84 people
- Sponsor
- GlaxoSmithKline
Frailty, Frailty Syndrome
Prevalence, Determinants and Natural History of Frailty and Pre-frailty in Elderly People
Frailty syndrome (i.e. frailty) is a geriatric syndrome which relies on the reduction of multisystem reserve capacity. Frail people have a lower potential to respond to external stressors and various life incidents as well as…
- Conditions
- Frailty, Frailty Syndrome, Frail Elderly Syndrome, Fragility
- Trial name
- FRAILPOL (NCT04518423)
- Where
- Poland
- Volunteers
- 1,093 people, healthy volunteers welcome
- Sponsor
- The Opole University of Technology
Muscle, Cognitive Functioning
This Study Investigates β-hydroxy-β-methylbutyrate (HMB) and 2-hydroxybenzylamine (2-HOBA), When Administered Either Individually or in Combination Contributes to an Increased Quality of Health, Specifically Improving Muscular Strength and Cognitive Functioning in Adults Over the Age of 65.
In this study, participants will be assigned to receive HMB, 2-HOBA, a combination of both, or a comparison supplement for a set period of time.
- Conditions
- Muscle, Cognitive Functioning, Geriatric, Ageing and Geriatric Health
- Trial name
- H2AGE (NCT07419633)
- Testing
- β-Hydroxy-β-methylbutyrate, 2-hydroxybenzylamine, β-Hydroxy-β-methylbutyrate and 2-hydroxybenzylamine
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Fabry Disease, Aged 65 Years or Older
Study of the Quality of Life of Patients With Fabry Disease Aged 65 and Over With and Without Specific Treatment
Fabry disease is a rare genetic disorder affecting 1 in 10,000 individuals, leading to complications such as chronic pain, heart and kidney failure, and strokes, ultimately impacting life expectancy.
- Conditions
- Fabry Disease, Aged 65 Years or Older, Alpha Galactosidase A Deficiency, Galactosidase A Gene Mutation
- Trial name
- FABRY65 (NCT07277361)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Wladimir MAUHIN, Dr
Frail Elderly, Dual Task Exercises in Elderly People
FreeFrail Project: A Multicomponent Intervention for the Management of Frailty in Primary Care: A Randomized Controlled Trial
The primary aim is to assess the effectiveness of a multicomponent intervention including dual-task exercise in improving functionality and cognitive performance and in reducing frailty among community-dwelling adults aged ≥65…
- Conditions
- Frail Elderly, Dual Task Exercises in Elderly People, Exercise Training, Frailty
- Trial name
- NCT07205016
- Testing
- Dual task exercise, Otago exercise
- Volunteers
- 220 people
- Sponsor
- Universitat de Lleida
Psychological Well Being, Psychological Flexibility
Finding With Nature: A Study Testing Nature-Based Support for Family Caregivers Aged 65 and Over
This research project investigates the effects of a nature-based programme (Finding with Nature, FWN), on psychological well-being, functioning, and nature connectedness among older adults (65 and older) who provide care for…
- Conditions
- Psychological Well Being, Psychological Flexibility, Physical Functioning, Burden, Caregiver
- Trial name
- FWN (NCT07821970)
- Testing
- Finding with Nature Programme
- Volunteers
- 350 people
- Sponsor
- JAMK University Of Applied Sciences
Frailty at Older Adults, Primary Care
Implementation of a Clinical Decision Support System in Primary Care for the Screening and Assessment of Frailty in Patients Aged 65 and Over
This observational study aims to evaluate the real-life use of a digital tool (Fragiclic) by general practitioners (GPs) and nurses to screen and assess frailty in adults aged 65 and over.
- Conditions
- Frailty at Older Adults, Primary Care, Geriatric Assessment, Implementation Research
- Trial name
- FRAGICLIC (NCT07570628)
- Where
- France
- Volunteers
- 726 people, healthy volunteers welcome
- Sponsor
- CNGE Conseil
Antiphospholipid Syndrome
Prevalence and Consequences of Antiphospholipid Syndrome in Patients Aged 65 and Over With Ischemic Strokes (IS)
Stroke represents a major cause of morbidity and mortality despite significant progress in recent decades. In individuals under the age of 65, the etiologies of ischemic stroke (IS) are diverse, and management is…
- Trial name
- SAPLAGE (NCT07163338)
- Testing
- Collectio nof blood
- Where
- France
- Volunteers
- 400 people
- Sponsor
- CHU de Reims
Loneliness
Compartiendo Salud: Community-Based Intervention for Loneliness
Unwanted loneliness is the gap between the social relations a person has and those they want. The main objective of this research is to assess the impact of a multidimensional community-based intervention on the feeling of…
- Trial name
- SoledadLP (NCT06829758)
- Testing
- Compartiendo Salud
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Servicio Canario de Salud
Active Aging Individuals Aged 65 and Over, Aging
Italian Validation of the dNA Scale and Its Correlation With Neurocognitive Variables
The goal of this experimental multicentric intervention study is to validate, in Italian, the dynamic Neurocognitive Adaptation (dNA) Scale, which has already been validated in English, among a healthy elderly population (aged 65…
- Conditions
- Active Aging Individuals Aged 65 and Over, Aging, Mild Cognitive Impairment (MCI), Dementia
- Trial name
- NCT07533084
- Where
- 8 sites in Italy
- Volunteers
- 265 people, healthy volunteers welcome
- Sponsor
- Neuromed IRCCS