Clinical trials: Overactive Bladder
Overactive Bladder, Bladder Pain Syndrome
Bladder Botox UTI Antibiotic Prophylaxis
Overactive bladder (OAB) is a common condition with a prevalence of 17% in the general population that significantly affects quality of life.
- Trial name
- NCT06387329
- Testing
- Nitrofurantoin 100 MG
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Walter Reed National Military Medical Center
Overactive Bladder, Caffeine
"The Effects of Caffeine on Overactive Bladder Symptoms and Mental Health in Postmenopausal Women"
The purpose of this study is to observe effects of caffeine on overactive bladder symptoms and wellbeing. This study looks at whether caffeine has bad effects on urinary symptoms or if lower doses of caffeine decrease the…
- Conditions
- Overactive Bladder, Caffeine, Menopause
- Trial name
- NCT02180048
- Testing
- 400 mg of caffeine/day (Two 200mg pills/day)
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Bladder, Overactive
Genital Nerve Stimulation - GNS - for Treatment of Non-neurogenic OAB
The Genital Nerve Stimulation - GNS - consists of a two-step procedure with a preoperative non-surgical test-phase and a final surgical implantation of the neuroprothesis.
- Trial name
- GNS (NCT04160793)
- Testing
- Genital Nerve Stimulation
- Where
- Switzerland
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. med. Marc Possover
Over Active Bladder
BlueWind Medical System for the Treatment of Patients With OAB
BlueWind system safety and performance in treatment of patients diagnosed with overactive bladder (OAB)
- Trial name
- OAB (NCT02299544)
- Testing
- BlueWind Medical system
- Where
- 6 sites in Netherlands, United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- BlueWind Medical
Bladder Function
Pilot Trial in Sleep Laboratory Setting to Compare the Physiology of Night Time Bladder Function in Subjects With Overactive Bladder (OAB) Versus Subjects That Have Insomnia and Healthy Normal Subjects
This is an observational, physiology pilot study of subjects with overactive bladder, insomnia and normal subjects. No study drug will be given. All subjects will complete a one week sleep diary and a 3-day bladder diary.
- Trial name
- Nocturia Plt 1 (NCT01029015)
- Testing
- cystometry, polysomnography
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Inc
Overactive Bladder, Renal Colic
Preoperative Use of Darifenacin (Enablex) to Alleviate Postoperative Ureteral Stent Pain
This will be a randomized two arm prospective study to evaluate postoperative ureteral stent pain. One arm will be given 3 days of preoperative darifenacin and the control group will have the standard of care which is no…
- Conditions
- Overactive Bladder, Renal Colic, Pain, Postoperative
- Trial name
- NCT01189071
- Testing
- Darifenacin
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Visceral Adiposity Index
Visceral Adiposity Index and Overactive Bladder
In present study, we aimed to investigate the association between visceral adiposity index and overactive bladder symptoms in female patients aged over 18 years.Between January-2015 and July-2017, 151 female patient with…
- Trial name
- NCT03280654
- Testing
- overactive bladder
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Urge Urinary Incontinence, Overactive Bladder
Bringing Simple Urge Incontinence Diagnosis & Treatment to Providers (BRIDGES)
Six hundred and thirty-six women diagnosed with urge urinary incontinence (UUI) by a three-item self-administered questionnaire (3IQ) will be randomized to 12 weeks of fesoterodine or matching placebo.
- Trial name
- BRIDGES (NCT00862745)
- Testing
- Fesoterodine
- Where
- 13 sites in United States
- Volunteers
- 645 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Overactive Bladder Syndrome
Post-treatment Novmalized Urodynamiz Findings as the Golden Standard of Objective Cure for Female Overactive Bladder Patients Receiving Antimuscarinic Drug
Post-treatment Novmalized Urodynamiz Findings as the Golden Standard of Objective Cure for Female Overactive Bladder Patients Receiving Antimuscarinic Drug and Its Conelations With Voiding Diary, King's Health Quentionaire…
- Trial name
- NCT01627145
- Testing
- Solifenacin
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Incontinence, Overactive Bladder, Stress Urinary Incontinence
Investigation of the Suburothelial Myofibroblast Network and of Smooth Muscle Function and Control in the Human Urinary Outflow Tract
The aim is to find out if adreno-muscarinic synergy is present also in human tissues of the urinary outflow tract that have a dual adrenergic-muscarinic receptor fitting.
- Trial name
- NCT01227447
- Where
- Germany
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich
SGLT2 Inhibitors, Lower Urinary Track Symptoms
SGLT-2 Inhibitors and Lower Urinary Tract Symptoms
This prospective observational study aims to evaluate the effects of sodium-glucose cotransporter 2 (SGLT-2) inhibitors on lower urinary tract symptoms (LUTS) in patients with type 2 diabetes mellitus.
- Conditions
- SGLT2 Inhibitors, Lower Urinary Track Symptoms, Overactive Bladder
- Trial name
- NCT07716774
- Testing
- No Intervention: Observational Cohort
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Marmara University
Overactive Bladder, Stress, Psychological
Stress and Anxiety Effects on Overactive Bladder
The purpose of this study is to assess how psychological stress and anxiety relate to bladder sensitivity and to psychological burdens in people with overactive bladder and how this can be measured effectively.
- Conditions
- Overactive Bladder, Stress, Psychological, Anxiety
- Trial name
- NCT05087810
- Testing
- Psychological stress induction, Accelerated oral hydration
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Overactive Bladder
A Study to Evaluate Safety, Tolerability and Pharmacokinetics of DA-8010 in Healthy Subjects
This study is a Phase I, Randomised, Double-Blind, Placebo-Controlled, Dose-Escalation Study to Evaluate Safety, Tolerability and Pharmacokinetics After Single and Multiple Oral Administration of DA-8010 in Healthy Subjects.
- Trial name
- NCT02821312
- Testing
- DA-8010
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Dong-A ST Co., Ltd.
Overactive Bladder
A Study To Test The Interaction of Two Medications for Treatment of Overactive Bladder
The purpose of this study is to determine the effect of repeat doses of solabegron and oxybutynin when taken alone or together
- Trial name
- NCT00501267
- Testing
- solabegron and oxybutynin
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Urinary Incontinence
Translating Unique Learning for Incontinence Prevention
More than one in three US women suffers from the distressing, embarrassing, and often unreported problem of urinary incontinence (UI). UI severity increases with age and the financial cost exceeds $19 billion per year .
- Trial name
- TULIP (NCT01599715)
- Testing
- Instructional DVD, Bladder Health Class
- Where
- 2 sites in United States
- Volunteers
- 647 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Overactive Bladder Syndrome, Urinary Urge Incontinence
Cycling Study With the Axonics System
A prospective, multi-center, study comparing continuous sacral neuromodulation (SNM) stimulation to daily cyclic stimulation of 2 hours "on" and 22 hours "off" using the Axonics System.
- Conditions
- Overactive Bladder Syndrome, Urinary Urge Incontinence, Sacral Neuromodulation
- Trial name
- NCT05543382
- Testing
- Axonics System
- Where
- 6 sites in United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Axonics, Inc.
Urinary Frequency/Urgency
Development of Novel Cystometrics for Overactive Bladder
Urinary urgency is the key symptom of overactive bladder (OAB). A critical barrier in understanding OAB is the lack of a method to separate urgency that derives directly from bladder filling or what we term "tension sensor…
- Trial name
- NCT02060214
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Overactive Bladder, Urgency-frequency Syndrome
OAB and the Microbiome
To determine differences in the urinary microbiomes, identified by polymerase change reaction (PCR) (UTIP™), of female patients with urgency and frequency syndrome with or without pelvic pain (Group A) compared to female controls…
- Trial name
- NCT04831801
- Where
- 2 sites in United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Miami
Urge Incontinence
Randomized Trial of Tibial Nerve Stimulation Versus Pelvic Floor Exercises for Treatment of Overactive Bladder
Urinary incontinence is defined according to the International Continence Society as any involuntary loss of urine, which may bring several negative consequences on women's lives, and among incontinent women, about 50% have…
- Trial name
- NCT02452593
- Testing
- "Tibial stimulation" and "pelvic floor exercises"
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Overactive Bladder, Urge Incontinence
Transcutaneous Tibial Nerve Stimulation: the ZIDA Device Equivalence
Tibial nerve stimulation (TNS) has been shown to be an effective alternative for the management of the overactive bladder (OAB).
- Conditions
- Overactive Bladder, Urge Incontinence, Urinary Incontinence, Urinary Frequency More Than Once at Night
- Trial name
- NCT04470765
- Testing
- Zida
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Exodus Innovations