Clinical trials: Overload
Fluid Overload, Anesthesia; Adverse Effect, Spinal and Epidural
Can Vena Cava Ultrasound Guided Volume Repletion Prevent Spinal Induced Significant Hypotension in Elective Patients?
Aim of this study is to determine whether Inferior Vena Cava analyzed by trans-thoracic echocardiography is an effective method to guide titrated fluid repletion in non critical patients, in order both to decrease post procedural…
- Conditions
- Fluid Overload, Anesthesia; Adverse Effect, Spinal and Epidural, Regional Anesthesia Morbidity
- Trial name
- NCT02271477
- Testing
- Ultrasound-guided volemic repletion
- Where
- Switzerland
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Complications; Cesarean Section, Anesthesia; Adverse Effect, Spinal and Epidural
Fluid Coloading and the Incidence of Hypotension
This study was conducted to evaluate the effects of rapid crystalloid (Lactated Ringer's solution) or colloid (hydroxyethyl starch; HES) cohydration with a second intravenous access line on the incidence of hypotension and…
- Conditions
- Complications; Cesarean Section, Anesthesia; Adverse Effect, Spinal and Epidural, Other Fluid Overload
- Trial name
- NCT01741610
- Testing
- Cristalloid and colloid coloading
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Idiopathic Pulmonary Hemosiderosis
Efficacy of Bone Marrow Mesenchymal Stem Cell in Pulmonary Hemosiderosis
Pulmonary hemosiderosis (PH) is a pulmonary hemosiderin deposition which caused by alveolar capillary hemorrhage. PH is easy to recurrent and can lead to pulmonary fibrosis and insufficiency if the disease was poor controlled.
- Trial name
- NCT02985346
- Testing
- Bone marrow mesenchymal stem cells in treatment of Idiopathic pulmonary hemosiderosis
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Thalassemia
Zinc and Diabetes in Patients With Thalassemia: a Pilot Study
The primary aim of this study is to measure zinc status and related proteins in patients with Thalassemia who have or do not have diabetes.
- Trial name
- NCT01772680
- Testing
- Zinc Supplementation
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- UCSF Benioff Children's Hospital Oakland
Sepsis, Fluid Overload
Investigation of Novel and Established Therapies in a Human Intravenous Lipopolysaccharide Model of Sepsis
Sepsis is a common and life-threatening condition caused by a dysregulated host immune response to infection. Given the prominent role of endothelial breakdown and dysfunction in sepsis, therefore, there is an urgent need to…
- Conditions
- Sepsis, Fluid Overload, Endothelial Dysfunction, Microcirculation
- Trial name
- INITIALISE (NCT06626984)
- Testing
- Imatinib, Compound sodium lactate solution
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Belfast Health and Social Care Trust
Phosphate Overload
Phosphate Bioavailability Hormonal Response to a Breakfast Meal in Healthy Humans
Convenience food is enhanced with phosphate additives in order to modify taste and texture and for preservation. The purpose of this study is to measure the response of phosphate-related hormones to two different types of…
- Trial name
- NCT05401552
- Testing
- Meal
- Where
- 2 sites in Canada
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Clinical Evaluation Research Unit at Kingston General Hospital