Clinical trials: Overweight,Obesity
Obesity, Overweight
Cardiovascular Outcomes Study of Naltrexone SR/Bupropion SR in Overweight and Obese Subjects With Cardiovascular Risk Factors (The Light Study)
The purpose of this study is to determine the effects of NB relative to placebo on major adverse cardiovascular events (MACE) such as cardiovascular death, non-fatal myocardial infarction, and non-fatal stroke in overweight and…
- Trial name
- NCT01601704
- Testing
- NB32, PBO, Weight Management Program
- Where
- 224 sites in United States
- Volunteers
- 8,910 people
- Sponsor
- Orexigen Therapeutics, Inc
Obesity, Weight Loss
Lifestyle Behavior Weight Loss Intervention
This lifestyle behavior intervention aims to weight loss in low-income overweight or obese mothers of young children through promotion of stress management, healthy eating, and physical activity.
- Trial name
- NCT04649047
- Testing
- Goal-oriented episodic future thinking
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Obesity, Hypertension
A Randomized Clinical Trial To Study Losartan On Endothelial Dysfunction and Insulin Resistance In Obese Patients
The main purposes of this study are to find out if the study drug losartan (Cozaar) or placebo ("sugar pill") has an effect on insulin sensitivity (how your body responds to insulin) and to measure the effect of the study drug…
- Conditions
- Obesity, Hypertension, Hyperglycemia
- Trial name
- NCT00675987
- Testing
- losartan
- Where
- 9 sites in United States
- Volunteers
- 53 people
- Sponsor
- Brigham and Women's Hospital
Obesity
School Water Access, Food and Beverage Intake, and Obesity
It is widely argued that the promotion of water consumption, as an alternative to sugar-sweetened beverages, can assist in childhood obesity prevention efforts.
- Trial name
- NCT03181971
- Testing
- Water First
- Where
- United States
- Volunteers
- 1,861 people
- Sponsor
- Stanford University
Healthy Diet, Obesity
Effect of Ultra-processed Versus Unprocessed Diets on Energy Metabolism
Protocol Number: 22DK0002 Title: Effects of Ultra-processed versus Unprocessed Diets on Energy Metabolism Background: Many diets worldwide include both processed and unprocessed foods.
- Trial name
- NCT05290064
- Testing
- Ultra-processed food, high energy density (UPF HL), Ultra-processed food, both low (UPF LL), Ultra-processed food, both high (UPF HH)
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Child Obesity
Improving Parent-Child Interactions to Enhance Child Health
Childhood obesity is a formidable public health issue in the United States, disproportionately affecting children from lower socioeconomic status households.
- Trial name
- PCIT-Health (NCT03982511)
- Testing
- PCIT-Health
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Central Michigan University
Hypertension
International Multicenter, Observational, Non-Interventional Prospective Study of Azilsartan Medoxomil in Participants With Arterial Hypertension Who Are Overweight or Obese in the Russian Federation and The Republic of Kazakhstan
The purpose of this study is to estimate antihypertensive effect of azilsartan medoxomil (Edarbi®) therapy on blood pressure in participants with overweight or obesity in routine clinical practice of hypertension (HTN) treatment…
- Trial name
- NCT02756819
- Testing
- Azilsartan Medoxomil
- Where
- 66 sites in Kazakhstan, Russia
- Volunteers
- 1,945 people
- Sponsor
- Takeda
Obesity, Overweight
A Study of Tirzepatide in Overweight and Very Overweight Participants
The main purpose of this study is to measure the effect of tirzepatide on food intake in participants who are overweight or very overweight.
- Trial name
- NCT04311411
- Testing
- Tirzepatide, Liraglutide
- Where
- 3 sites in United States
- Volunteers
- 114 people
- Sponsor
- Eli Lilly and Company
Diabetes
Lifestyle Intervention in Overweight and Obese Pregnant Hispanic Women
The overall goal of this randomized controlled trial is to test the efficacy of a culturally and linguistically modified, individually tailored lifestyle intervention to reduce excess gestational weight gain (GWG), increase…
- Trial name
- NCT01868230
- Testing
- Lifestyle Intervention
- Where
- United States
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Amherst
Diabetes, Diabetes Mellitus, Type 2
Comparison of the Change in Fat Distribution in Overweight and Obese Subjects With Type 2 Diabetes After Insulin Treatment
This trial is conducted in Europe. The aim of this clinical trial is to compare the change in trunk fat mass, assessed by Double Energy X-ray Absorptiometry (DEXA) after 26 weeks of treatment with insulin detemir or insulin NPH…
- Trial name
- NCT00795600
- Testing
- insulin detemir, insulin NPH
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Novo Nordisk A/S
Weight Loss, Obesity
Weight Management in Rural Communities
The goal of this study is to evaluate the effect of three weight management interventions (group phone conference calls, individual phone calls, and enhanced usual care) on weight across 18 months in overweight and obese adults…
- Conditions
- Weight Loss, Obesity, Body Weight
- Trial name
- M-DEx (NCT02932748)
- Testing
- Portion Controlled Meals (PCM), Group Phone (GP), Conventional Diet
- Where
- United States
- Volunteers
- 187 people
- Sponsor
- University of Kansas
Obesity, Colorectal Carcinoma
Legume Diet Satiety Pilot Study
This pilot study is designed to test the effects of a high legume (dried bean) diet on hunger and other indicators of health over the course of eight weeks, compared to a more conventional healthy diet.
- Trial name
- NCT02269631
- Testing
- Legume diet group, Control diet group, Smartpill
- Where
- 2 sites in United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Emory University
Atelectasis, Pulmonary Infection
Bi-PAP vs Sham Bi-PAP on Pulmonary Function in Morbidly Obese Patients After Bariatric Surgery
The effect of biphasic positive airway pressure (Bi-PAP) at individualized pressures on the postoperative pulmonary recovery of morbidly obese patients (MOP) undergoing open bariatric surgery (OBS) and possible placebo…
- Conditions
- Atelectasis, Pulmonary Infection, Chronic Obstructive Pulmonary Disease (COPD), Pulmonary Disease
- Trial name
- NCT03438383
- Testing
- Bi-PAP
- Volunteers
- 48 people
- Sponsor
- Evangelismos Hospital
Obesity, Obesity, Childhood
Healthy Homes, Healthy Habits
The purpose of this study is to evaluate whether an intervention targeting healthy habit development reduces the risk and prevalence of obesity in low-income mothers and children.
- Conditions
- Obesity, Obesity, Childhood, Obesity; Familial
- Trial name
- HABITS (NCT03433456)
- Testing
- Home visitation + HABITS program, Standard home visitation program
- Where
- United States
- Volunteers
- 296 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Breast Cancer, Obesity
Effect of Weight on the Population Pharmacokinetic Analysis of Doxorubicin and Cyclophosphamide
To determine the effect of weight on doxorubicin and cyclophosphamide plasma clearance in participants who are normal weight (body mass index [BMI] < 25 kg/m2, overweight or class I obese (BMI 25-34.9 kg/m2), or class II-III…
- Trial name
- NCT01537029
- Testing
- Doxorubicin, Cyclophosphamide
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Texas Tech University Health Sciences Center
Childhood Obesity
Physical Activity and Screen-Time Regulations in Childcare Centers - Aim 1
The goal of this project is to examine the physical activity and screen-time environment of licensed childcare centers before and after the enactment of new state regulations.
- Trial name
- Pause and Play (NCT02751788)
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Type 2 Diabetes, Obesity
Metabolomic Analysis of Hepatic Insulin Resistance
This is a pilot study to show that it is possible to identify the specific types of fats in blood, adipose tissue, and liver tissue.
- Trial name
- NCT01833403
- Testing
- Hyperinsulinemic-euglycemic clamp
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Obesity, Leptin Resistance
Effect of Increased Free Fatty Acids on Leptin Function
Obese people have elevated levels of the hormone leptin. Despite this, they seem to be resistant to the effects of this hormone, which usually regulates appetite and energy expenditure.
- Trial name
- NCT01520454
- Testing
- Saline, Intralipid, Water
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Prader-Willi Syndrome
Phase 3 Study of Intranasal Carbetocin (LV-101) in Patients With Prader-Willi Syndrome
This Phase 3 study is designed to test the effectiveness of intranasal carbetocin (LV-101) in participants with Prader-Willi syndrome (PWS). Carbetocin is an oxytocin analog (a man-made chemical that is like oxytocin).
- Trial name
- CARE-PWS (NCT03649477)
- Testing
- 3.2 mg intranasal carbetocin, 9.6 mg intranasal carbetocin
- Where
- 24 sites in United States, Australia and 1 more
- Volunteers
- 130 people
- Sponsor
- Levo Therapeutics, Inc.
Obesity
A Study of Once-Daily Oral Orforglipron (LY3502970) in Japanese Adult Participants With Obesity Disease
The main purpose of this study is to investigate the efficacy and safety of oral orforglipron in participants with obesity disease with obesity-related health problems.
- Trial name
- ATTAIN-J (NCT05931380)
- Testing
- Orforglipron
- Where
- 16 sites in Japan
- Volunteers
- 238 people
- Sponsor
- Eli Lilly and Company
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.