Clinical trials: Overweight/Obese Population
Obesity
Healthy Lifestyle Program: A Novel Group-based Training
The Healthy Lifestyle Program involves twelve, 2-hour seminars during which participants will learn how to build healthy behaviors through a combination of individual and group exercises.
- Trial name
- NCT05083962
- Testing
- Healthy Lifestyle Program
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Overweight (BMI > 25), Obesity and Overweight
The Effect of a ChatGPT-Supported Online Group-Guided Self-Help Program on Uncontrolled and Emotional Eating Behaviors and Body Image in Overweight and Obese Woman Nurses
Nurses with overweight and female gender characteristics often experience disruptions in their eating behaviors due to stressful working conditions.
- Conditions
- Overweight (BMI > 25), Obesity and Overweight, Emotional Eating, Binge Eating
- Trial name
- NCT06653673
- Testing
- ChatGPT supported Online Guided Self-Help Program (GSHP)
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Obesity
Population Based Intervention to Prevent Obesity in Kindergartens (TigerKids)
Behavioral intervention at Kindergarten setting aiming at increased fruit and vegetable consumption, decreased intake of high energy foods, snacks, sweets, increased intake of water/low energy drinks, decreased intake of high…
- Trial name
- NCT00336128
- Testing
- attitude change, adiposity prevention program
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich
Cardiovascular Disease, Obesity
Vitamin D Ancillary Study in 5 Populations of African Origin
The availability of data on plasma 25-Hydroxyvitamin D (25(OH)D) concentrations in the last two rounds of the National Health and Nutrition Examination Survey (NHANES) has generated a high level of interest in the consequences of…
- Trial name
- VIDA (NCT02111902)
- Where
- 5 sites in United States, Ghana and 3 more
- Volunteers
- healthy volunteers welcome
- Sponsor
- Loyola University
Heart Diseases, Type2 Diabetes
Psychosocial, Environmental, and Chronic Disease Trends in Puerto Rico
The overall goal is to identify trends and longitudinal associations in psychosocial, food-related, and cardiometabolic risk factors that can guide public health priorities and future research needs aimed at reducing…
- Conditions
- Heart Diseases, Type2 Diabetes, Hypertension, Obesity
- Trial name
- PROSPECT (NCT03794531)
- Where
- Puerto Rico
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Obesity & Overweight, Vulnerable Families
Evaluation of a Multicomponent Early Intervention for Childhood Obesity Prevention in Vulnerable Families
Childhood obesity is a public health concern. Evidence-based, multicomponent, parenting interventions targeting early childhood and adapted to families' socioeconomic context are needed to prevent childhood obesity.
- Conditions
- Obesity & Overweight, Vulnerable Families, Children, Families With Infants
- Trial name
- Bambú (NCT07529704)
- Testing
- Bambú program
- Where
- 4 sites in Spain
- Volunteers
- 526 people, healthy volunteers welcome
- Sponsor
- Helena Vall Roqué
Obesity
Effect of Entacapone on Bodyweight Loss in Obese Population
This is a randomized, controlled, double blind clinical trial. The purpose of this study is to investigate the weight loss efficacy of entacapone.
- Trial name
- NCT02349243
- Testing
- Entacapone
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Kaichun Wu
Obesity
A Comparison of the Metabolic Effects of Fructose, Glucose, High Fructose Corn Syrup and Sucrose at Normal Population Consumed Levels in Adults Aged 20-60 Years Old
The purpose of this study is to investigate the acute and chronic effects of consumption fructose containing sugars and glucose in a real word setting when consumed in a manner and amount typical in the American diet.
- Trial name
- NCT01797042
- Testing
- Dietary Compliance
- Where
- United States
- Volunteers
- 366 people, healthy volunteers welcome
- Sponsor
- Rippe Lifestyle Institute
Healthy Volunteer
A Multiple Dose Study Of Ertugliflozin (PF-04971729, MK-8835) In Otherwise Healthy Overweight And Obese Volunteers (MK-8835-037)
Ertugliflozin (PF-04971729, MK-8835) is under development for the treatment of Type 2 Diabetes. The primary purpose of this trial is to evaluate the safety and tolerability, pharmacokinetics and pharmacodynamics, of multiple oral…
- Trial name
- NCT01018823
- Testing
- Ertugliflozin
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Overweight and Obesity
A Trial to Assess Bioavailability of AMG 133 in Participants With Overweight or Obesity
The primary objective of the trial is to evaluate the pharmacokinetics (PK) of AMG 133 administered as a single subcutaneous (SC) dose using a liquid drug product in vial compared to a frozen liquid drug product in vial in…
- Trial name
- NCT07717814
- Testing
- AMG 133 (frozen liquid), AMG 133 (liquid)
- Where
- 4 sites in United States
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Amgen
Body Weights and Measures, Body Weight in the Overweight and Obese Class - I Population
Machine Learning and 3D Image-Based Modeling for Real-Time Body Weight and Body Composition Estimation During Emergency Medical Care: Study 2
The goal of this prospective crossover simulation study is to evaluate the accuracy and usability of a 3D camera weight estimation system during simulated emergency care in adult simulated patients, when used by emergency…
- Conditions
- Body Weights and Measures, Body Weight in the Overweight and Obese Class - I Population, Weight Estimation, Emergency Drug Dosing
- Trial name
- NCT06646133
- Testing
- 3D camera weight estimate, Standard methods of weight estimation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Florida Atlantic University
Behavior, Eating
Menu to Meal (M2M) Menu Labeling Intervention Study
This study evaluates the impact of culturally tailored menu labeling interventions on psychosocial factors and ordering behavior among customers in two independently owned Hispanic restaurants in East-Central Texas.
- Trial name
- NCT07329452
- Testing
- Paper menu, Digital menu condition
- Where
- United States
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Child Health, Child Behavior
Children's Cooperation Denmark: a 3-year System Dynamics Trial
Lack of physical activity (PA) and sedentary lifestyle in Danish children is a major challenge. New strategies are needed to combat this development.
- Conditions
- Child Health, Child Behavior, Physical Inactivity, Child Obesity
- Trial name
- Child-COOP (NCT06185413)
- Testing
- Participatory system dynamics approach
- Where
- 5 sites in Denmark
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Oxidative Stress
Clinical Trial to Investigate the Efficacy and Safety of LN-OS-22 on Oxidative Stress and Systemic Inflammation in Overweight and Obese Population.
The present clinical investigation has been proposed to further substantiate the evidence of the antioxidant and anti-inflammatory activity of the extract in the healthy adult population with BMI ranging from ≥25.0 kg/m2 and ≤…
- Trial name
- NCT05404217
- Testing
- LN-OS-22, Maltodextrin
- Where
- 3 sites in India
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
Overweight and Obesity, T2DM (Type 2 Diabetes Mellitus)
Effect of Viscous Soluble Fibres on Body Weight
Abstract: Background: Obesity is a global pandemic affects all age groups and is independent risk factors for most chronic diseases. Dietary intervention is an essential component of obesity management.
- Conditions
- Overweight and Obesity, T2DM (Type 2 Diabetes Mellitus), General Population
- Trial name
- NCT03257449
- Testing
- Viscous Fibre
- Where
- Canada
- Volunteers
- 1,268 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Breast Cancer, Obesity
Nutritional Intervention-induced Weight Loss During the Oncological Treatment of Obesity-related Breast Cancer
Obesity could become the first evitable cause of breast cancer in the near future. Due to the relatively slow rate of development in this field, greater efforts must be applied in this area.
- Conditions
- Breast Cancer, Obesity, Weight Change, Body, Epigenetic Disorder
- Trial name
- NUTOBREST (NCT06046755)
- Testing
- Very low calorie ketogenic diet (VLCKD), Group educational intervention program (IGOBE)
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Hospital Clinico Universitario de Santiago
Atrial Fibrillation, Coronary Heart Disease
EMPOWER-1: A Multi-site Clinical Cohort Research Study to Reduce Health Inequality
Health inequality and genetic disparity are a significant issue in the United Kingdom (UK). This study focuses on diseases that are associated with significant morbidity and mortality in the UK, and specifically examines the…
- Conditions
- Atrial Fibrillation, Coronary Heart Disease, Cardiovascular Diseases, Heart Failure
- Trial name
- EMPOWER (NCT03987633)
- Where
- United Kingdom
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- Future Genetics Limited
Strain of Muscle and/or Tendon of Lower Leg, Fracture of Lower Leg
A Comparison of Two Injection Locations in Obese Patients Having Lower Leg/Foot Surgery
One technique for the nerve block involves injecting the numbing medicine where the nerve is together (higher up in the back of the thigh).
- Conditions
- Strain of Muscle and/or Tendon of Lower Leg, Fracture of Lower Leg, Crushing Injury of Lower Leg, Fracture Malunion - Ankle and/ or Foot
- Trial name
- NCT01550094
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Jose Soberon, MD
Obesity, Morbid, Eating Disorder Symptom
Mindfulness Based Eating Awareness Training for Bariatric Surgery Patients
The purpose of this study is to evaluate the effects of Mindfulness Based Eating Awareness Training (MB-EAT) for patients who have had bariatric surgery on their weight and mental and physical health compared to patients who do…
- Trial name
- MB-EAT (NCT03488966)
- Testing
- Mindfulness Based Eating and Awareness Training
- Where
- Canada
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Prediabetes, Overweight
Evaluation of Prevent in Underserved Populations
The goal of this study is to evaluate an online Diabetes Prevention Program adapted for patients with prediabetes in safety net health care settings.
- Conditions
- Prediabetes, Overweight, Obesity
- Trial name
- PUP (NCT02664064)
- Testing
- Prevent
- Where
- 3 sites in United States
- Volunteers
- 227 people, healthy volunteers welcome
- Sponsor
- Omada Health, Inc.