Clinical trials: Overweight/Obese Population
Overweight and Obesity, Pregnancy Related
Healthy Lifestyle Before and During Pregnancy to Prevent Childhood Obesity - the PRE-STORK-trial
Introduction: The prevalence of childhood overweight and obesity has risen from just 4% in 1975 to more than 18% in 2016. Little is known about adiposity of the infant, but it positively associates to the mother's BMI.
- Trial name
- NCT05578690
- Testing
- Diet, Exercise, Mentorship
- Where
- Denmark
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Steno Diabetes Center Copenhagen
Obesity, Eating Disorders
Psychometric Proprieties and Validation of Self-report Measures of Eating Behaviors
Obesity is a global epidemic and a major contributor to some of the leading causes of death. Although research on overweight and obesity is constantly increasing, to date, in the Italian panorama, there is a lack of (A) rigorous…
- Trial name
- Valid-OB (NCT05804292)
- Testing
- Questionnaire administration
- Where
- Italy
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Istituto Auxologico Italiano
Obesity, Inactivity
IT-based Training in Obesity
Though possibly cost-saving, there is little scientific evidence for the effectiveness and reasonable modality of internet-delivered physical activity interventions in primary prevention.
- Trial name
- NCT00899964
- Testing
- Physical activity
- Where
- Germany
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Obesity
Effect of LAPS-Exendin on Body Weight in Obese Population
The purpose of this study is to determine the optimal dose and regimen of HM11260C, in combination with a hypocaloric diet, to reduce weight in obese subjects who are otherwise considered in stable health.
- Trial name
- NCT02075281
- Testing
- HM11260C
- Where
- United States
- Volunteers
- 297 people, healthy volunteers welcome
- Sponsor
- Hanmi Pharmaceutical Company Limited
Obesity
A Study to Characterise the Physiology of Weight Loss and Regain Under Dietary, Behavioural and Pharmacological Interventions in Healthy Obese Subjects
Approximately 60 obese, but otherwise healthy, subjects will be assessed in this benchmark study to investigate the physiological changes associated with weight loss and regain.
- Trial name
- NCT01597609
- Testing
- sibutramine
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Obesity
Efficacy of D-allulose on Weight and Fat Loss and Insulin Resistance in Non-diabetic Obese Subjects
Prospective, randomized, double-blind, controlled-trial 30 subjects in each groups Group - I consume pure D-allulose 5 g 3 times a day before meal to right after meal (with any liquid) and Group - II control group with…
- Trial name
- NCT02988999
- Testing
- D-allulose, erythritol
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chiang Mai University
Overweight/Obesity, Metabolic Dysfunction-associated Steatotic Liver Disease/Steatohepatitis (MASLD/MASH)
A Single-Dose Pharmacokinetic Study of HRS-4729 Injection in Healthy Participants and Patients With Renal Impairment
This study aims to evaluate the pharmacokinetic effects of a single dose of HRS-4729 injection in participants with mild, moderate, and severe renal impairment, with 8 participants enrolled in each renal impairment group and 8…
- Conditions
- Overweight/Obesity, Metabolic Dysfunction-associated Steatotic Liver Disease/Steatohepatitis (MASLD/MASH), Type 2 Diabetes Mellitus
- Trial name
- NCT07807059
- Testing
- HRS-4729
- Where
- China
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Fujian Shengdi Pharmaceutical Co., Ltd.
Body Composition, Obesity
Development and Validation of Equations to Evaluate Body Composition in Colombian Population - F20 Project
The assessment of body composition is one of the main components within the evaluation of nutritional status under the ABCDE model.
- Trial name
- NCT05450588
- Where
- Colombia
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Dynamical Business and Science Society - DBSS International SAS
Obesity
Polyglucosamine L112 in Overweight and Obese Subjects
This research proposes as its main purpose to evaluate the effectiveness of the intake of Polyglucosamine at a dose of 3 g / day on weight loss in a group of subjects suffering from overweight and mild obesity (BMI between 25 and…
- Trial name
- NCT05022732
- Testing
- Polyglucosamine L112
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Azienda di Servizi alla Persona di Pavia
Obesity
Steps Ahead, Adapting Physical Activity Guidelines for the Lower Mississippi Delta Population
The Lower Mississippi Delta (LMD) population is characterized by high levels of overweight and obesity, which are the result of long-term disruptions in energy imbalance where dietary energy intake has exceeded energy expenditure…
- Trial name
- NCT01584596
- Testing
- Adapted Dietary Guidelines, Adapted Physical Activity Guidelines
- Where
- United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Obesity, Pharmacokinetics
Effect of Weight and/or Obesity on Sulfamethoxazole and Trimethoprim Concentrations
This study will find how weight affects the dosing of a drug called sulfamethoxazole and trimethoprim. Currently, the amount of sulfamethoxazole and trimethoprim a patient receives is the same regardless of the patient's weight.
- Conditions
- Obesity, Pharmacokinetics, MRSA, Tuberculosis
- Trial name
- NCT01167452
- Testing
- Sulfamethoxazole/trimethoprim
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Morbid Obesity
Population PK/PD of Propofol in the Morbidly Obese Patient
Rationale: The extreme increase of obesity in the last years had led to this study. There is no consensus about how to anaesthetise morbidly obese patients.
- Trial name
- NCT00395681
- Testing
- Diprivan
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- St. Antonius Hospital
Prediabetes, Obesity & Overweight
Human Pilot Study for the Investigation of the Role of Bilberry and Olive Bioactives on Oxidative Stress Parameters and Inflammatory Markers.
Numerous plant-based foods contain bioactive compounds, in particular polyphenols, which have antioxidant, anti-inflammatory, and metabolic regulatory effects.
- Conditions
- Prediabetes, Obesity & Overweight, Inflamation, Oxidative Stress
- Trial name
- BIOTRANSFORM (NCT07659028)
- Testing
- supplementation, food
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Obesity, Overweight
Nutrition and Soccer for Pediatric Overweight and Obesity
This study will examine whether two months of youth soccer, combined with a single brief behavioral/nutritional intervention, can reduce BMI in 5th grade overweight or obese females.
- Trial name
- NCT00365651
- Testing
- Youth Soccer
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Leach Chiropractic Clinic
Obesity, Mycoses
Effect of Weight and/or Obesity on Anidulafungin Drug Concentrations
This study will find how weight affects the dosing of a drug called anidulafungin. Currently, the amount of anidulafungin a patient receives is the same regardless of the patient's weight.
- Trial name
- NCT01307930
- Testing
- Anidulafungin
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Healthy Participants
A Trial to Assess the Relative Bioavailability of Different Subcutaneous Formulations of AZD9550 and AZD6234
This study in healthy volunteers aims to compare blood levels and side effects after administration of different formulations of two test medicines, AZD9550 and AZD6234.
- Trial name
- NCT07911514
- Testing
- AZD9550 solution for injection, AZD6234 solution for injection, Formulation 1 solution for injection
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Overweight, Obesity
Activity Monitoring and Counseling in a Geriatric Population
The goal of the study is to determine if a Fitbit, a kind of accelerometer, provides feedback to subjects combined with an activity counseling program will result in an increase in physical activity of at least 20%.
- Trial name
- NCT01502007
- Testing
- Accelerometer feedback and lifestyle counseling, Accelerometer without Feedback
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Overweight and Obesity
Betaine Supplementation and Lipid Metabolism in Overweight and Obese Pre-menopausal Women
Obesity represents a serious global health issue with significant consequences, including an increased risk of chronic diseases.
- Trial name
- NCT06344377
- Testing
- Betaine
- Where
- Poland
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Poznan University of Life Sciences
Obesity
Research Study of Nutritional Methods to Reduce Body Fat Percentages in Overweight and Obese Populations
The purpose of this study is to compare the use of personalized low-fat meal plans vs. non-personalized low-fat meal plans and the results in body fat reduction in overweight and obese subjects 25 to 45 years of age.
- Trial name
- NCT00487344
- Testing
- Non-Personalized Meal Planning, Personalized Meal Planning and Dietetic Consultation
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Central FITT, Inc
Obesity
Safety and Efficacy of Low Doses of V24343 in Obese Subjects
Randomised, double-blind, parallel group comparison of four dose levels of V24343 and placebo to study the effect of V24343 on blood pressure and weight in obese subjects.
- Trial name
- NCT00734201
- Testing
- V24343
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Vernalis (R&D) Ltd