Clinical trials: Overweight and Obese Women
Obesity, Pregnancy
Diet and Physical Activity Counseling and n3-long Chain (PUFA) Supplementation in Obese Pregnant Women
In Chile, 1 out of 4 pregnant women is obese (BMI > 30 kg/m2). This impacts negatively the health of the mother and the offspring during pregnancy.
- Trial name
- MIGHT (NCT02574767)
- Testing
- Lifestyle counseling, PUFA Supplementation, Routine diet & PA
- Where
- Chile
- Volunteers
- 1,002 people
- Sponsor
- University of Chile
Hypertension in Pregnancy, Hypertension
Enhancing Intergenerational Health in Nigeria: Peripartum as Critical Life Stage for Cardiovascular Health
The purpose of the ENHANCE-CVH study is to promote intergenerational cardiovascular health (CVH) of women and children in Abuja and the surrounding Federal Capital Territory of Nigeria.
- Conditions
- Hypertension in Pregnancy, Hypertension, Obesity and Overweight, Maternal Morbidity and Mortality
- Trial name
- ENHANCE-CVH (NCT06773299)
- Testing
- PAT+HEALTH curriculum - Nigeria
- Where
- Nigeria
- Volunteers
- 1,000 people
- Sponsor
- Washington University School of Medicine
Polycystic Ovary Syndrome
Study of Pharmacodynamics of LIK066 in Overweight and Obese Women With Polycystic Ovary Syndrome
The purpose of the study was to evaluate whether LIK066 can be developed for the treatment of polycystic ovary syndrome (PCOS) in overweight and obese women.
- Trial name
- PCOS (NCT03152591)
- Testing
- LIK066
- Where
- 5 sites in United States, Germany
- Volunteers
- 29 people
- Sponsor
- Novartis Pharmaceuticals
Lung Function Decreased, Obesity
Lung Functions in Menopausal Obese Women After COVID 19 Recovery
The COVID-19 pandemic has presented considerable challenges to global health services and dictates almost every aspect of medical practice and policy.
- Conditions
- Lung Function Decreased, Obesity, Menopause, Covid19
- Trial name
- NCT05008991
- Testing
- Spirometry
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Badr University
Obesity, Women
Lactobacillus Plantarum and Hormonal Regulation in Obese Women
To evaluate the regulatory effect of Lactobacillus plantans Lp90 formula on visceral fat metabolism and sex hormone balance in obese women.
- Trial name
- NCT06987279
- Testing
- Probiotic, Maltodextrin
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Body Weight, Visceral Obesity
Effects of Hydroxytyrosol Administration in Anthropometric Parameters in Overweight and Obese Women
This study aims to investigate the potential effects of the administration of hydroxytyrosol, which is an extra virgin olive oil phenolic compound, in doses 15 milligrams and 5 milligrams daily versus placebo for 6 months in…
- Trial name
- NCT04317079
- Testing
- Hydroxytyrosol, Diet
- Where
- Greece
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Pre Diabetes, Polycystic Ovary Syndrome
Liraglutide 3mg (Saxenda) on Weight, Body Composition, Hormonal and Metabolic Parameters in Obese Women With PCOS
There is a growing need to develop pharmacologic interventions to improve metabolic function in women with polycystic ovary syndrome (PCOS).
- Conditions
- Pre Diabetes, Polycystic Ovary Syndrome, Obesity Android
- Trial name
- SAXAPCOS (NCT03480022)
- Testing
- Liraglutide Pen Injector [Saxenda]
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Woman's
Pregnancy Complications, Maternal Obesity
Gasdermin-D and Pannexin-1 in Pregnancy
One -third of fertile women around the world are overweight or obese. This means increasing risk for both the mother and the child.
- Trial name
- NCT05475951
- Testing
- Biomarker measurement of pannexin-1 and gasdermin-D
- Where
- Turkey (Türkiye)
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Haseki Training and Research Hospital
Physical Inactivity, Obesity
Walking For Wellness Program Evaluation
The overall purpose of this project is to conduct an innovative, culturally-tailored demonstration project designed to facilitate the adoption and maintenance of regular, moderate physical activity (i.e., brisk walking) in a…
- Trial name
- NCT00156351
- Testing
- Physical activity promotion
- Where
- United States
- Volunteers
- 186 people
- Sponsor
- University of Pennsylvania
Obesity, Pregnancy
Bringing NELIP for Obese Pregnant Women Into Clinical Practice
This is a pilot project in which investigators will recruit obese (pre-pregnancy BMI of ≥ 35 kg/m2) women from the newly developed "My Clinic" at London Health Sciences Centre as well as normal obstetrical care at London Health…
- Trial name
- NCT02155751
- Testing
- Nutrition Lifestyle Intervention Program (NLIP), Exercise Lifestyle Intervention Program (ELIP)
- Where
- Canada
- Volunteers
- 23 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Obesity
Biology and Experience of Eating in Women With Obesity
The purpose of this study is to understand how the opioid system is involved in eating behavior.
- Trial name
- BEE (NCT02805972)
- Testing
- Naloxone
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Pregnancy, Obese
Validation of Ultrasound in Predicting a Low Lying Placenta Throughout Pregnancy
This is a prospective observational study comparing venous Doppler flow in the lower extremities of pregnant women. Pregnant women with a BMI >/= 30 will be compared to those with a BMI < 30.
- Trial name
- NCT02689739
- Testing
- venous duplex ultrasound
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Obesity, Fertility
Effects of Dietary Omega-3 Fatty Acids on Reproductive Hormones in Obese Women
The United States has the highest prevalence of obesity among all countries surveyed in 2012 by the Organization for Economic Cooperation and Development.
- Trial name
- NCT01894581
- Testing
- LOVAZA, GnRH
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Amino Acid, Body Weight Changes
A Specialized Amino Acid Mixture on Body Composition and Skin State in Overweight and Obese Class I Postmenopausal Women
The use of dietary amino acids has been explored for therapeutic and safety intervention of obesity and obesity-induced dysfunction.
- Conditions
- Amino Acid, Body Weight Changes, Skin Manifestations, Obesity
- Trial name
- NCT04701463
- Testing
- L-glutamine, L-arginine and calcium beta-hydroxy-beta-methylbutyrate
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Azienda di Servizi alla Persona di Pavia
Obesity, Overweight
Effects of Betahistine Hydrochloride in Overweight Women
This study will evaluate the effects of a drug called betahistine on appetite and food intake in overweight women. Betahistine has been used for many years to treat vertigo (dizziness).
- Conditions
- Obesity, Overweight, Overnutrition
- Trial name
- NCT00459992
- Testing
- Betahistine Hydrochloride
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Infections Joint Prosthetic, Overweight or Obesity
Antibiotic Prophylaxis in High-Risk Arthroplasty Patients
To determine the effectiveness of a 7-day course of an oral, prophylactic antibiotic on the incidence of periprosthetic joint infection and wound complications following primary total hip and knee arthroplasty in a high-risk…
- Conditions
- Infections Joint Prosthetic, Overweight or Obesity, MSSA Colonization, MRSA
- Trial name
- NCT04297592
- Testing
- Cephalexin, Doxycycline, Cefadroxil
- Where
- 2 sites in United States
- Volunteers
- 4,618 people
- Sponsor
- Mayo Clinic
Obesity
Theory-Based Obesity Intervention Program for Women
The aim of this study is to examine the effect of education and counseling given to women according to the Theory of Planned Behavior on weight management.
- Trial name
- NCT05027750
- Testing
- Application of The Theory of Planned Behaviour For Weight Control
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Childhood Obesity Prevention
Anthropometric Outcomes of a Mobile Health Intervention for Eating Behaviour and Lifestyle in Infancy
Lifestyle, activity, and feeding behaviours during early childhood set the foundation for subsequent lifelong metabolic health as an adult.
- Trial name
- NCT06457750
- Testing
- Feeding, Lifestyle, Activity Goals (FLAGs) Digital Health Application
- Where
- Singapore
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Healthy Women
Timing of Food Intake Impacts Daily Rhythms of Human Saliva Microbiota
The purpose of this investigation is to test the hypothesis that in humans, eating late may induce changes in saliva microbiota daily rhythms towards a more obesogenic and a less responsiveness to dietary treatments profile.
- Trial name
- ONTIME-MIC (NCT03147703)
- Testing
- Food Timing
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
Overweight, Obesity
Effectiveness of PUSH Notifications From a Mobile App for Improving the Body Composition of Overweight or Obese Women
A clinical three-armed assay has been established to permit an evaluation of the effectiveness of implementing PUSH notifications in the actions orientated towards improving body composition through the establishment of dietary…
- Trial name
- NCT03911583
- Testing
- Control Group (CG), Moderate physical activity group (MPA), Intense physical activity group (IPA)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Universidad de Córdoba
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