Clinical trials: Overweight and Obese Women
Diabetes, Obesity & Overweight
Exercise and Tissue-Specific Insulin Sensitivity in South Asian and Nordic Women With Previous Gestational Diabetes
South Asian women have a high risk of developing type 2 diabetes, and the risk is particularly high after gestational diabetes. This study examined whether eight weeks of supervised vigorous exercise improves insulin sensitivity…
- Trial name
- DIASA-Ex (NCT07843082)
- Testing
- Exercise
- Where
- Norway
- Volunteers
- 43 people
- Sponsor
- Oslo University Hospital
Diabetes Mellitus, Type 2, Kidney Disease, Chronic
Randomized Study Comparing Metabolic Surgery With Intensive Medical Therapy to Treat Diabetic Kidney Disease
Proven therapy for DKD is primarily limited to RAAS blockers and SLGT2i. Weight reduction has the potential to become an additional and much needed treatment option.
- Conditions
- Diabetes Mellitus, Type 2, Kidney Disease, Chronic, Kidney Injury
- Trial name
- OBESE-DKD (NCT04626323)
- Testing
- Roux-en-Y gastric bypass, Best medical treatment
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Hospital Alemão Oswaldo Cruz
Childhood Obesity, Anemia
The Jiaxing Birth Cohort in China
The Jiaxing Birth Cohort (JBC) is the largest prospective cohort study to explore prenatal risk factors, early life feeding practice and growth pattern/ adiposity in Chinese children.Between 1999 and 2013, 338 413 mother-child…
- Conditions
- Childhood Obesity, Anemia, Pregnancy Complications, Pregnancy; Hypertension
- Trial name
- JBC (NCT03217656)
- Testing
- No intervention
- Where
- China
- Volunteers
- 500,000 people, healthy volunteers welcome
- Sponsor
- Zhejiang University
Obesity, Chronic Kidney Disease
Patient-centred Intervention With Virtual Support for Obesity and Kidney Transplant Access
Obesity has a serious impact on people's health and quality of life. For those with advanced kidney disease (i.e. approaching the need for dialysis), obesity is especially problematic - obesity can not only lead to worsening…
- Conditions
- Obesity, Chronic Kidney Disease, Chronic Renal Disease, CKD
- Trial name
- PIVOT (NCT07858331)
- Testing
- Semaglutide, Virtual Weight Management Coaching
- Where
- 2 sites in Canada
- Volunteers
- 880 people
- Sponsor
- Kristin Clemens
Insulin Resistance, Impaired Glucose Tolerance
Cassia Cinnamon for Glucose Uptake in Young Women
The purpose of this study was to compare the acute effects of 5g of Cassia cinnamon, 50 minutes of endurance exercise performed at 70% of the heart rate reserve (correlated to VO2max), and 5g of cellulose placebo on blood…
- Conditions
- Insulin Resistance, Impaired Glucose Tolerance, Prediabetes
- Trial name
- NCT00951639
- Testing
- Cassia cinnamon, 50 minutes exercise, Cellulose Powder
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Baylor University
Hot Flushes, Menopause, Premature
The Role of Vitamin D in Menopause: Relationship to Menopausal Symptoms in Body Composition
Specific Aim 1: To compare effects of Vitamin D supplementation to usual care on symptoms in women transitioning to early postmenopause and determine the associated effect size in order to conduct a power analysis for a future…
- Conditions
- Hot Flushes, Menopause, Premature, Obesity, Vitamin D Deficiency
- Trial name
- FLASH (NCT01141972)
- Testing
- Vitamin D
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Obesity, Stress
Brain-Gut Interactions in Overweight and Normal Weight Patients With Chronic Abdominal Pain
About 15 to 20 percent of individuals living in the United States have chronic abdominal pain, often of unknown origin, which is often difficult to diagnose and treat.
- Conditions
- Obesity, Stress, Irritable Bowel Syndrome, Women
- Trial name
- NCT00824941
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- National Institute of Nursing Research (NINR)
Obese, Hyperlipidemia
Effects of Green Tea Extract on Obese Women With High Level of LDL
Green tea is one of the most popular beverages in the world. It is believed to have beneficial effect in prevention and treatment of many diseases, one of which is reducing LDL-C.
- Trial name
- GTE-LDL (NCT02116517)
- Testing
- green tea extract
- Where
- Taiwan
- Volunteers
- 73 people
- Sponsor
- National Yang Ming Chiao Tung University
Obesity, Obesity, Maternal
Obesity and OSA in Pregnancy
The purposes of this project are 1) to compare the impact of maternal obesity versus excessive gestational weight gain on obstructive sleep apnea (OSA) in obese and non-obese women; 2) to investigate the mechanism(s) by which…
- Conditions
- Obesity, Obesity, Maternal, Obstructive Sleep Apnea, Blood Pressure
- Trial name
- NCT05654259
- Where
- 2 sites in United States
- Volunteers
- 116 people
- Sponsor
- University of Texas Southwestern Medical Center
Overweight, Obesity
A Research Study Looking Into How NNC0662-0419 Works With Birth Control Pills and Emptying of the Stomach in Women Not Able to Become Pregnant With Excess Body Weight
The purpose of this clinical study is to find out if NNC0662-0419 is safe and effective to be taken together with other medicines, like birth control pills, and emptying of the stomach in women not able to become pregnant living…
- Trial name
- NCT07525791
- Testing
- NNC0662-0419, Oral contraceptive, Acetaminophen
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Morbid Obesity, Obstructive Sleep Apnea
Laparoscopic Adjustable Gastric Banding With Truncal Vagotomy
Laparoscopic Adjustable Gastric Banding (LAGB) is a gold standard in the surgical treatment of morbid obesity. We hypothesize that the addition of truncal vagotomy (cutting of nerves to the stomach) will produce greater weight…
- Conditions
- Morbid Obesity, Obstructive Sleep Apnea, Hypertension, Urinary Incontinence
- Trial name
- NCT00329862
- Testing
- Laparoscopic Truncal Vagotomy
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Central Carolina Surgery, PA
Obesity
Food Reward in Native American Women
This study aims to characterize the neurobiology of obesity in American Indians (AI) using functional MRIs to examine the correlation between brain response to food stimuli in AI women.
- Trial name
- NCT01623440
- Testing
- Naltrexone and fMRI
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Weight Loss, Ovarian Carcinoma
Skeletal Muscle Energy Metabolism in Women With Weight Loss and Ovarian and/or Endometrial Cancer With Weight Loss
the aim is to study skeletal muscle metabolism alterations métaboliques associated with weight loss in women with ovarian and/or endometrial cancer according to BMI.
- Conditions
- Weight Loss, Ovarian Carcinoma, Endometrial Carcinoma
- Trial name
- METERMUS-IMC (NCT03027479)
- Testing
- Samples
- Where
- France
- Volunteers
- 70 people
- Sponsor
- University Hospital, Tours
Hemodialysis Patients
Impact on the Proteolysis of Obesity in Dialysis
The objective of this study is to determine whether obesity has a protective effect on muscle proteolysis in hemodialysis patients submitted to a short starvation.
- Trial name
- IPOD (NCT01114789)
- Testing
- Proteolysis
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Hypertension, Obesity
Preparing a Food is Medicine Intervention to Promote Healthy Eating and Blood Pressure Control
Hypertension and obesity are both major risk factors for cardiovascular disease (CVD), a leading cause of death for Black women in the United States.
- Conditions
- Hypertension, Obesity, Healthy Nutrition, Blood Pressure
- Trial name
- NCT05796648
- Testing
- RN-CHeFRx
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Illinois Chicago
Childhood Obesity
Coordination of Care Between Pediatricians and Women Infants & Children Nutritionists
WEE Baby Care is a 6 month intervention that coordinates care across multiple settings- health care clinics and WIC clinics on responsive parenting practices to increase parenting competence thereby preventing infant rapid weight…
- Trial name
- WEE (NCT03482908)
- Testing
- Early healthy lifestyles, Responsive parenting curriculum, Data sharing/coordination
- Where
- United States
- Volunteers
- 289 people, healthy volunteers welcome
- Sponsor
- Penn State University
Obesity
Effectiveness of Rice Germ Supplementation on Body Composition, Metabolic Parameters, Satiating Capacity and Amino Acid Profiles in Obese Postmenopausal Women
Rice germ (RG) may be a safe and effective dietary supplement for obesity in menopause, considering its high protein content and considerable amounts of essential amino acids, good fatty acids, and fiber.
- Trial name
- NCT04695418
- Testing
- Rice Germ
- Where
- Italy
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Azienda di Servizi alla Persona di Pavia
Overweight, Obesity
Pedometer Use to Prevent Excessive Pregnancy Weight Gain in Overweight Women
The purpose of this study is to evaluate pedometer use by overweight women during pregnancy. The study will show if a pedometer will help women to limit weight gain during pregnancy.
- Conditions
- Overweight, Obesity, Pregnancy
- Trial name
- NCT01469260
- Testing
- Pedometer
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Stanford University
Spinal Muscular Atrophy, Fragile X Syndrome
Early Check: Expanded Screening in Newborns
Early Check provides voluntary screening of newborns for a selected panel of conditions. The study has three main objectives: 1) develop and implement an approach to identify affected infants, 2) address the impact on infants and…
- Conditions
- Spinal Muscular Atrophy, Fragile X Syndrome, Fragile X - Premutation, Duchenne Muscular Dystrophy
- Trial name
- NCT03655223
- Testing
- Confirmatory Testing
- Where
- United States
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- RTI International
Obesity, Hormone Disturbance
Bariatric Surgery, Hormones, and Quality of Life
The purpose of this study is to characterize the hormonal status in fertile women undergoing laparoscopic gastric bypass, pre- and postoperatively, and evaluate if there is a correlation between health-related quality of life and…
- Conditions
- Obesity, Hormone Disturbance, Quality of Life, Hyperandrogenism
- Trial name
- OBLIV (NCT03188640)
- Testing
- Laparoscopic gastric-bypass surgery
- Volunteers
- 68 people
- Sponsor
- Linkoeping University
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