Clinical trials: Overweight and Obesity
Pediatric Obesity
LA Sprouts: The Impact of Gardening and Nutrition Education on Childhood Obesity in Latino Youth
The overall goal of this project is to conduct a randomized controlled 12-week after school, gardening, nutrition and cooking program (called "LA Sprouts") to improve dietary intake and reduce obesity in 3rd, 4th and 5th grade…
- Trial name
- LA Sprouts (NCT02291146)
- Testing
- LA Sprouts intervention
- Where
- United States
- Volunteers
- 421 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Overweight, Obesity
Changing Eating Behaviors of Healthy Adults Through Hypnosis
There is a lot of research on weight loss. In spite of the research on the subject, obesity is a growing disease all through the world.
- Trial name
- NCT04178486
- Testing
- Hypnosis with amnesia suggestions, Hypnosis with cognitive rehearsal suggestions, Hypnosis with memory substitution suggestions
- Where
- Romania
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Babes-Bolyai University
Daily Self-weighing, Daily Temperature-taking
Self-Weighing: an Ecological Momentary Assessment
The primary objective of this study is to experimentally test the momentary and more distal psychological effects of daily self weighing as compared to an active control group.
- Trial name
- SWEMA (NCT03273491)
- Testing
- daily self-weighing, daily temperature-taking
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Obese
Comparative Effects of Using Black Seed and Cumin Seed on BCP of Obese Grade I
The goal of this Randomized clinical trial is to compare effectiveness of of using black seed (Nigella sativa) and cumin seed (Cuminum cyminum) on Body composition profile of obese grade 1.
- Trial name
- NCT05770791
- Testing
- Black Seed ( Nigella Sativa), Cumin Seed (Cuminum Cyminum)
- Where
- Pakistan
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Sehat Medical Complex
Obesity, Insulin Resistance
The Health Influences of Puberty (HIP) Study
The Health Influences of Puberty (HIP) Study is designed to explore the relationships between puberty and the onset of type 2 diabetes in adolescents.
- Conditions
- Obesity, Insulin Resistance, Gonadal Dysfunction, Type 2 Diabetes
- Trial name
- HIP (NCT01775813)
- Testing
- Metformin
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- University of Colorado, Denver
Obesity, Morbidly Obese
Novel SaCoVLM™ Video Laryngeal Mask Airway as an Intubation Conduit in Morbidly Obese Bariatric Surgery
Background: The SaCoVLM™ video laryngeal mask is a novel video-assisted device that integrates the functions of both a dual-channel laryngeal mask airway (LMA) and an intubating laryngeal mask airway (ILMA).
- Trial name
- NCT07573813
- Testing
- SaCoVLM™ in Difficult Airways
- Where
- China
- Volunteers
- 57 people
- Sponsor
- Yongtao Sun
Healthy Participants
A Study of Safety of SUN-0864 and How it is Processed by and Affects the Body in Healthy Adults and Healthy Adults Who Are Overweight or Obese.
This Phase 1, first-in-human study will evaluate the safety and tolerability of SUN-0864, how the body processes SUN-0864, and how SUN-0864 affects the body in healthy adults and otherwise healthy adults who are overweight or…
- Trial name
- NCT07905560
- Testing
- SUN-0864 (Formulation 1) or SUN-0864 (Formulation 2)
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Superluminal Medicines, Inc.
Severe Obesity
Resting Metabolic Rate is a Predictor of Weight Regain?
he increasing prevalence of obesity in developed countries has also reached Brazil in the last two decades. Conventional treatments are not efficient to sustained weight loss and in some cases, weight reduction in individuals…
- Trial name
- NCT04118582
- Testing
- Body composition and resting metabolic rate analisys
- Where
- Brazil
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Hypertension, Atrial Fibrillation
Evaluation of a Non-Invasive Electrocardiogram-Assisted Blood Pressure Monitor
Approximately one billion people suffer from hypertension worldwide. At least 10% of this population, that is, 100 million people, also suffers from associated chronic conditions namely, atrial fibrillation (AF), obesity…
- Conditions
- Hypertension, Atrial Fibrillation, Obesity, Heart Failure
- Trial name
- NCT02053623
- Where
- Canada
- Volunteers
- 3 people
- Sponsor
- Health Parametrics Inc.
Obesity, Cardiovascular Disease
BNP Pharmacodynamics and Effects on Metabolism in Lean and Obese Subjects
The purpose of this study is to collect data to help researchers better understand the various causes of obesity, which may lead to the development of new obesity treatment options.
- Conditions
- Obesity, Cardiovascular Disease, Hypertension, Diabetes
- Trial name
- NCT01977859
- Testing
- Nesiritide, Saline
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- AdventHealth Translational Research Institute
Weight Loss, Obesity
A Study to Assess the Effect of a Normal vs. High Protein Diets in Carbohydrates Metabolism in Obese Subjects With Diabetes or Prediabetes
The objective of the study is to assess the effect of low-calorie diets with normal (18%) vs. high (35%) protein (mainly coming from animal source) composition on body weight and carbohydrates metabolism in overweight and obese…
- Conditions
- Weight Loss, Obesity, Diabetes, Diet, Reducing
- Trial name
- NCT02559479
- Testing
- Weight loss interventional study with a low-calorie 18%-protein diet, Weight loss interventional study with a low-calorie 35%-protein diet
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Instituto Aragones de Ciencias de la Salud
Obesity
Pediatric Hypothalamic Obesity
This trial is being conducted in pediatric patients with Hypothalamic Obesity. This generally occurs in people who have had an injury to or tumor in their hypothalamus (gland or organ that secretes hormones).
- Trial name
- NCT00076362
- Testing
- Sandostatin LAR
- Where
- 15 sites in United States
- Volunteers
- 60 people
- Sponsor
- Novartis Pharmaceuticals
Obesity, Ulcerative Colitis
A Study of Endoscopic Sleeve Gastroplasty for Obesity in Ulcerative Colitis
The purpose of this research is to gather information on the safety and effectiveness of Endoscopic Sleeve Gastroplasty (ESG) for weight loss in a population of obese UC patients undergoing colectomy with eventual IPAA.
- Trial name
- NCT05739162
- Testing
- Apollo Endoscopic Suture System, Lifestyle Intervention
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Mayo Clinic
PCOS (Polycystic Ovary Syndrome), Obese Adolescents
Lean Beef as Part of a Healthy Meal Plan in Adolescents With Polycystic Ovary Syndrome (PCOS)/Polyendocrine Metabolic Ovarian Syndrome (PMOS)
This pilot randomized controlled study will plan to enroll 36 adolescent females with Polycystic Ovary Syndrome (PCOS)/Polyendocrine Metabolic Ovarian Syndrome (PMOS) to evaluate the effectiveness and feasibility of a tailored…
- Conditions
- PCOS (Polycystic Ovary Syndrome), Obese Adolescents, Overweight (Without Type 2 Diabetes) With Weight-related Comorbidities, Overweight Adolescents
- Trial name
- Beef+ (NCT07780188)
- Testing
- Beef+
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Texas A&M University
Obesity
A Study of BioEnterics® Intragastric Balloon (BIB®) System to Assist in the Weight Management of Obese Subjects
Safety and effectiveness of the BIB® System in conjunction with a behavior modification program compared to the behavior modification program alone for weight loss in obese subjects.
- Trial name
- NCT00730327
- Testing
- BioEnterics® Intragastric Balloon, Behavioral modification
- Where
- United States
- Volunteers
- 448 people
- Sponsor
- Apollo Endosurgery, Inc.
Polycystic Kidney, Autosomal Dominant
Daily Caloric Restriction and Intermittent Fasting in Overweight and Obese Adults With Autosomal Dominant Polycystic Kidney Disease
The proposed research will determine the feasibility of delivering two behavioral weight loss interventions for 1 year in adults with autosomal dominant polycystic kidney disease (ADPKD) who are overweight or obese.
- Trial name
- NCT03342742
- Testing
- Weight Loss
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- University of Colorado, Denver
Obesity and Overweight
The Efficacy and Safety of Efsubaglutide Alfa Injection in Overweight and Obese Subjects (ENLIGHT)
This study is a multicenter, randomized, double-blind, placebo-controlled Phase IIb/III clinical trial aimed at evaluating the efficacy, safety, pharmacokinetics (PK), and immunogenicity profile of Efsubaglutide Alfa injection in…
- Trial name
- NCT06921486
- Testing
- Phase IIb：Efsubaglutide Alfa 5 mg QW, Phase IIb：Efsubaglutide Alfa 10 mg QW, Phase IIb：Efsubaglutide Alfa 20 mg QW
- Where
- 41 sites in China
- Volunteers
- 1,003 people
- Sponsor
- Shanghai Yinnuo Pharmaceutical Technology Co., Ltd.
Overweight, Obese
An Engagement Engine for Fitness Trackers
The iTrackFitness study aims to test the "engagement engine" that was developed from activity tracker and survey data gathered during phase I of the study.
- Trial name
- iTrackFitnes (NCT02960386)
- Testing
- Machine Learning Algorithm
- Where
- United States
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Overweight
Physical Activity Consultation in the Management of Adolescent Overweight
The prevalence of pediatric obesity makes this condition a worldwide public health concern. Physical Activity (PA) is recognized as having many health benefits, many of them related to obesity and its comorbidities.
- Trial name
- PAC-MAnO (NCT02941770)
- Testing
- Physical activity behavior change, Exercise
- Where
- Portugal
- Volunteers
- 165 people
- Sponsor
- University of Lisbon
Time Restricted Feeding, Exercise
Time-Restricted Eating, Exercise and Cardiometabolic Health in Obesity
In Spain, overweight and obesity prevalence is reaching 70% in men and 50% in women. Excess of triglycerides are usually stored in the subcutaneous adipose tissue (SAT), until a point where SAT is unable to expand further.
- Conditions
- Time Restricted Feeding, Exercise, Hepatic Steatosis, Cardiometabolic Syndrome
- Trial name
- TEMPUS (NCT05897073)
- Testing
- Time-restricted eating intervention, Exercise intervention, Time-restricted eating plus exercise intervention
- Where
- 2 sites in Spain
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada