Clinical trials: Ovulation
Ovulation Induction, Polycystic Ovary Syndrome
Myo-inositol Versus Clomiphene Citrate in PCOS
Specific aim: To compare inositol and the golden standard first line treatment of ovulation induction, namely clomiphene citrate.
- Conditions
- Ovulation Induction, Polycystic Ovary Syndrome, Clomiphene, Inositol
- Trial name
- NCT04306692
- Testing
- Myo-inositol, Clomiphene Citrate
- Where
- Belgium
- Volunteers
- 12 people
- Sponsor
- University Hospital, Ghent
Inositol, Testosterone
Evaluation of D-chiro-inositol Treatments
Healthy women will take tablets containing 600 mg D-chiro-inositol twice per day for one month. We will evaluate metabolic and hormonal.parameters, as insulienmia, glycemia, estradiol, testosterone.
- Conditions
- Inositol, Testosterone, Insulin, Ovulation
- Trial name
- NCT05448378
- Testing
- D-chiro-inositol
- Where
- 2 sites in Italy
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Lo.Li.Pharma s.r.l
Poor Response to Ovulation Induction, PCOS
The Angiotensin-Melatonin Axis in Poor and Hyper Responders for IVF Treatment
According the World Health Organization (WHO), infertility is a disease of the male or female reproductive system defined by the failure to achieve a pregnancy after 12 months or more of regular unprotected sexual intercourse.
- Conditions
- Poor Response to Ovulation Induction, PCOS, Endometriosis, Infertility, Female
- Trial name
- NCT05298657
- Where
- United Arab Emirates
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Fatima College of Health Sciences
Infertility, Female, Poor Response to Ovulation Induction
Does DHEA IVF Outcomes in Poor Responders?
This study is a RCT to examine whether DHEA is capable of improving results for poor responders to ovarian stimulation during IVF treatment
- Trial name
- DHEA (NCT04066478)
- Testing
- Dehydroepiandrosterone
- Where
- United Kingdom
- Volunteers
- 400 people
- Sponsor
- Homerton University Hospital NHS Foundation Trust
Ovulation Disorder, Ovarian Cysts
The Role of Estrogen in Luteinizing Hormone Surge and Ovulation
The purpose of the study is to establish that sustained estrogen levels are the driving force for the LH surge, and are thereby necessary for ovulation to occur.
- Trial name
- NCT01999569
- Testing
- Letrozole
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
PCO, Induction of Ovulation
Parameters Declaring PCO Infertile Patients Either Sensitive or Resistant to Different Doses of Clomiphene Citrate.
Polycystic ovary syndrome (PCOS) is a common endocrinological disorder seen in 6%-10% of women (Human Reproduction, 2004). It is characterized by polycystic ovaries, anovulatory cycles, and hyperandrogenism.
- Conditions
- PCO, Induction of Ovulation, Clomiphene Citrate
- Trial name
- NCT04887402
- Testing
- Clomiphene Citrate
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Subfertility, Female, Ovulation Disorder
Serial Progesterone Level Measurements During the Menstrual Cycle in Subfertile Women
Ovulatory dysfunction is identified in 15% of all infertile couples and it accounts for 40% of female infertility. Ovulatory dysfunction may be more subtle in women with regular menses.
- Trial name
- NCT05211583
- Testing
- Serum progesterone levels
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Turgut Aydın
Poor Response to Ovulation Induction Poseidon Type IV
Growth Hormone Pretreatment in Poseidon Type IV Undergoing ICSI Using Minimal Induction Protocol: A Randomized Controlled Trial
This study is done aiming to Assess Efficiency of Growth hormone as an adjuvant in pretreatment of Poseidon type IV group " poor responders "undergoing ICSI using minimal induction protocol
- Trial name
- Growth hormone (NCT05089344)
- Testing
- Growth Hormone, Clomiphene citrate daily and recombinant FSH (Gonal-F®)
- Where
- Egypt
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Ovulation
Heart Rate Variability During the Menstrual Cycle
In this study, women will be required to wear a chest heart rate monitor and wrist heart rate monitor daily and collect daily early morning urine samples for the duration of one complete menstrual cycle.
- Trial name
- NCT04382001
- Where
- United Kingdom
- Volunteers
- 28 people
- Sponsor
- SPD Development Company Limited
Clomiphene Citrate Resistance, Ovulation Induction
Letrozole Versus Gonadotropins in Clomiphene Citrate Resistance
Clomiphene citrate resistance (CCR) occur in 15-40% in women with PCOS. Several studies have shown that letrozole is superior to CC regarding side effects, ovulation, and pregnancy rates.
- Conditions
- Clomiphene Citrate Resistance, Ovulation Induction, Letrozole, Gonadotropins
- Trial name
- NCT04834791
- Testing
- Letrozole 2.5mg, Gonadotropin
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Tanta University
Unexplained Infertility, Ovulation Disorder
Incremental Clomiphene Citrate Doses in Successive Cycles and FSH, LH and Steroid Hormone Levels
This study was planned to assess the initial and endogenous FSH, LH and steroid responses to incremental CC doses in successive ovulation induction cycles to treat anovulation in patients with unexplained infertility.
- Trial name
- NCT04210765
- Testing
- Clomiphene Citrate
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Bagcilar Training and Research Hospital
Infertility, Female, Polycystic Ovary Syndrome
Letrozole for Frozen Embryo Transfer (FET) in Patients With Polycystic Ovary Syndrome (PCOS)
To offer patients with oligomenorrhoea or amenorrhoea an alternative to frozen embryo transfer in an artificial cycle, endometrial preparation using letrozole may be a valuable option.
- Conditions
- Infertility, Female, Polycystic Ovary Syndrome, IVF, Ovulation Disorder
- Trial name
- LEFT (NCT04002635)
- Testing
- Letrozole, estradiol valerate
- Volunteers
- healthy volunteers welcome
- Sponsor
- CRG UZ Brussel
Ovulation Induction, Polycystic Ovary Syndrome
Effect of Adding Isoflavonoids to Clomiphene Citrate for Ovulation Induction in Women With Polycystic Ovary Syndrome
This prospective, randomized clinical trial double blinded study, has been carried on 160 infertile patients seeking pregnancy in Gynecology and Obstetrics Department, Zagazig University Hospitals during the period from January…
- Trial name
- NCT04610957
- Testing
- Rosafem (FEMININE FORMULA)
- Where
- Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- FAlbasri
Ovulation Disorder
Usability Study of the Pearl Fertility Tracking Device
This mobile application measures the level of certain hormones in the urine of a woman and is used to help pinpoint when the woman is/was most likely to get pregnant during her menstrual cycle.
- Trial name
- NCT03924453
- Testing
- Pearl Powered by Proov
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- MFB Fertility
Poor Response to Ovulation Induction, Infertility, Female
Optimal Embryonic Stage for Transfer in Poor Responders
A Prospective cohort study including couples with poor responder females who undergoing ICSI
- Trial name
- NCT04485819
- Testing
- Cleavage stage transfer, Blast stage transfer
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Ganin Fertility Center
Polycystic Ovary Syndrome, Ovulation
The Effect of Cinnamon on Ovulation Induction in Women With Polycystic Ovary Syndrome
Title: The effect of cinnamon supplementation on ovulation induction in women with polycystic ovary syndrome, Jeddah 2019: Randomized Double-Blind Placebo-controlled trial Phase: III Population: 118 women with polycystic ovary…
- Trial name
- PCOS (NCT03778099)
- Testing
- Cinnamon Cap 500 MG
- Where
- Saudi Arabia
- Volunteers
- 33 people
- Sponsor
- King Abdulaziz University
Ovulation
Investigation of Heart Rate Variability During the Menstrual Cycle
In this study, women will be required to wear a heart rate monitor continuously and collect daily early morning urine samples for the duration of one complete menstrual cycle.
- Trial name
- NCT04008277
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- SPD Development Company Limited
Ovulation; Failure or Lack of
Hormonal Effects of the Oral Gonadotropin Releasing Hormone (GnRH) Antagonist at Different Periods of the Menstrual Cycle
The purpose of this study is twofold: First, to see if elagolix can suppress gonadotropin and ovarian hormones in the short-term period, when only administered for a 72-hour period.
- Trial name
- NCT04060992
- Testing
- Elagolix 200 MG Oral Tablet [Orilissa]
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Ovulation, Luteal Development
The Effect of a Non-hormonal Cox-2 Inhibitor (Celebrex) on Ovulation
The purpose of this study is to assess the effect that Celebrex (a COX-2 inhibitor and non-steroidal anti-inflammatory drug) has on ovulation.
- Trial name
- NCT01129245
- Testing
- Celebrex
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Polycystic Ovary Syndrome, Infertility
Pulsatile Gonadotropin-releasing Hormone for Infertility in Non-obese Patients With Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) patients are often accompanied by infertility. Non-obese PCOS infertility is more difficult to treat than obese PCOS.
- Conditions
- Polycystic Ovary Syndrome, Infertility, Ovulation Disorder
- Trial name
- NCT03989024
- Testing
- Gonadorelin, Clomiphene
- Where
- China
- Volunteers
- 78 people
- Sponsor
- RenJi Hospital