Clinical trials: Oxidative Stress Induction
Postbiotics Supplement
The Effect of Postbiotics Supplementation on Exercise-induced Oxidative Stress.
Scientific data on the effect of supplementation of postbiotics on exercise-induced oxidative stress are scarce. The main purpose of the research is to investigate the effect of postbiotics supplementation on exercise-induced…
- Trial name
- PB-EIOS (NCT06417671)
- Testing
- Postbiotics supplementation
- Where
- Greece
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Muscle Damage
The Effect of New Zealand Blackcurrant (NZBC) Supplementation on Recovery Following Strenuous Exercise
The study aims to examine the effect of a New Zealand blackcurrant (NZBC) supplement on markers of muscle damage and recovery following strenuous resistance exercise.
- Trial name
- CurraNZ_MD (NCT05010057)
- Testing
- New Zealand blackcurrants (NZBC)
- Where
- United Kingdom
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Pregnancy Complications, Endothelial Dysfunction
Oxidative Stress and Endothelial Function in Pregnancy Complications
Pregnancy complications like pre-eclampsia (PE), pregnancy induced hypertension (PIH), intra-uterine growth restriction (IUGR) and preterm labor (PTL), (i.e.
- Trial name
- ENDOPREG (NCT02603913)
- Where
- Belgium
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Universiteit Antwerpen
Critical Illness
Evaluation of Oxidative Stress Induced by Iron Injection in Healthy Volunteers and Critical Care Patients
The purpose of this study is to evaluate the pro-oxidant toxicity of iron injections in critically ill patients and in healthy volunteers.
- Trial name
- SOFI (NCT01443624)
- Testing
- critical care patients venofer
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Neuroinflammatory Response, Nerve Injury
Assessment of Nerve Damage Biomarkers in Acute and Chronic Organophosphate Toxicity
The aim of this observational study is to answer the following questions in individuals with acute and chronic exposure to organophosphates. The main questions to be addressed are 1.
- Conditions
- Neuroinflammatory Response, Nerve Injury, Nerve Damage, Neurotoxicity
- Trial name
- NCT06021262
- Testing
- exposure to organophosphates
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Periodontitis (Stage 3), Smoking
Determination of RNA/DNA Damage Associated With Oxidative Stress in Periodontitis Patients
This study looked at whether a type of gum disease called Stage III periodontitis and cigarette smoking are linked to higher levels of "oxidative stress." Oxidative stress can damage DNA and RNA, which are important parts of our…
- Trial name
- NCT07279896
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Zehra Hasgül
Oxidative Stress
SIMOX - Induction of Oxidative Stress
The purpose of the study is to investigate if use of simvastatin is associated with the level of oxidative stress in humans. The association is examined by comparing changes in oxidative stress in a group treated with simvastatin…
- Trial name
- SIMOX (NCT02256254)
- Testing
- Simvastatin
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Hyperglycemia, Cardiovascular Disease
Green Tea Confections For Managing Postprandial Hyperglycemia-Induced Vascular Endothelial Dysfunction
The objective of this study is to formulate and validate a green tea confection (i.e. "gummy" candy) as a strategy to attenuate postprandial hyperglycemia-induced impairments in vascular function.
- Trial name
- NCT01857258
- Testing
- Green Tea Concentrate
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Preeclampsia (PE), Oxidative Stress
Assessment of Oxidative Stress Contents in Jordanian Pregnant Women With Preeclampsia
Preeclampsia, a widespread complication affecting pregnant women globally, necessitates a thorough investigation into the role of oxidative stress in its manifestation.
- Trial name
- Preeclampsia (NCT07119034)
- Testing
- Total cholesterol (TC), random blood glucose (RBG), triglyceride (TG), low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C)
- Where
- Jordan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Patients at Risk for Melanoma
Oral N-acetylcysteine for Protection of Human Nevi Against UV-induced Oxidative Stress/Damage in Vivo
This is a phase II intervention to propose a new melanoma chemoprevention agent. The investigators believe oxidative stress/damage in nevi is a probable indication for melanoma risk, and propose that reduced melanoma risk in…
- Trial name
- NCT01612221
- Testing
- N-acetylcysteine
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Utah
Smoking Cessation, Oxidative Stress
ESTxENDS Trial-Substudy on Oxidative Stress Induced by Electronic Nicotine Delivery Systems (ENDS) Measured in Urine
--> This is a substudy of the main ESTxENDS trial (NCT03589989). Oxidative stress outcomes should be considered secondary outcomes of the main smoking cessation outcome formulated in NCT03589989.
- Trial name
- ESTxENDS (NCT03612375)
- Testing
- ENDS (vaporizer/e-cig) and smoking cessation counseling, smoking cessation counseling
- Where
- 5 sites in Switzerland
- Volunteers
- 1,246 people, healthy volunteers welcome
- Sponsor
- University of Bern
Healthy, Athletes
Effects of Maca Supplementation on Badminton-specific Exercise Performance
This study aims to investigate whether a 14-day short-term supplementation of Maca can effectively mitigate oxidative stress and fatigue induced by badminton competition.
- Trial name
- NCT07082985
- Testing
- Maca (Maca trial)
- Where
- Taiwan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Inflammation
LycoRed 40051 Product as a Countermeasure to Exercise Stress
The primary purpose of this study is to determine if 4-weeks ingestion of LycoRed (code 40051) product containing a mixture of tomato extract with carotenoids and phytochemicals by endurance runners attenuates inflammation…
- Trial name
- NCT02369666
- Testing
- LycoRed (code 40051) product
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Preeclampsia
Thiol/Disulphide Homeostasis and Preeclampsia
Objective: To evaluate serum evaluate thiol/ disulfide levels in preeclampsia and address its relationship with its severity. Methods: This prospective study will include 50 pregnancies complicated with preeclampsia and 50…
- Trial name
- thiols&PE (NCT03927014)
- Testing
- thiol/disulfide levels
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cengiz Gokcek Women's and Children's Hospital
Exercise-induced Oxidative Stress
Physiological Effect of Ataulfo Mango (Manguifera Indica) Beverage in Exercise
The aim of this study is to assess the antioxidant capacity of two mango base beverages (AM1, AM2), against exercise-induced oxidative stress.
- Trial name
- NCT03182543
- Testing
- Mango pulp beverage, Mango pulp and peel beverage, Control beverage
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Ciudad Juarez
Lung Diseases
Analysis of Anti-inflammatory and Antioxidant Pathways in Lung Diseases by Haem Oxygenase-1 (HO-1) in Induced Sputum and Carbon Monoxide (CO) in Exhaled Air
This work will focus on the anti-inflammatory and antioxidant pathways in lung diseases by measuring HO-1 in induced sputum and CO in exhaled air in cases of four respiratory diseases, asthma, chronic obstructive pulmonary…
- Trial name
- NCT01140685
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Acidosis, Oxidative Stress
Effects of Zeolite + Dolomite on Performance and Acidosis
Purpose: This study investigates the effects of dietary zeolite + dolomite on performance, exercise-induced acidosis, oxidative stress, inflammation and intestinal barrier dysfunction in trained people.
- Conditions
- Acidosis, Oxidative Stress, Inflammation
- Trial name
- NCT01831492
- Testing
- zeolite + dolomite, cellulose
- Where
- Austria
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Green Beat
Nephrotoxicity, Acute Kidney Injuries
Rutin and Ascorbic Acid for Prevention of Vancomycin-Induced Nephrotoxicity in Adult Patients" - a Clinical Trial Protocol Evaluating Whether Combined Rutin/Vitamin C Supplementation Reduces Kidney Toxicity From Vancomycin, Compared to Vitamin C Alone and Control.
Background: Vancomycin, a key antibiotic for MRSA infections, frequently causes nephrotoxicity (kidney damage) via oxidative stress, especially at the higher doses and longer durations now recommended.
- Trial name
- NCT07873372
- Testing
- Rutin + Ascorbic Acid (RUTA C60®), Ascorbic Acid (C-Retard®)
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Intense Exercise
Bananas as an Energy Source During Exercise: a Metabolomics Approach
This study compared the acute effect of ingesting bananas (BAN) versus a 6% carbohydrate drink (CHO) on 75-km cycling performance and post-exercise inflammation, oxidative stress, and innate immune function using traditional and…
- Trial name
- NCT01581190
- Testing
- Bananas versus 6% carbohydrate beverage
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Noise-induced Hearing Loss
Protective Effects of EPI-743 on Noise-Induced Hearing Loss
If effective, administration of EPI-743 should have protective effects against temporary noise-induced hearing loss.
- Trial name
- NCT02257983
- Testing
- EPI-743
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Edison Pharmaceuticals Inc