Clinical trials: Oximetry
Regional Saturation of Oxygen (rSO2)
Performance Comparison of Masimo O3 Regional Oximetry Sensors in Neonates
The aim of the study is to compare the performance of the O3 cerebral oximeter and sensor to a 510(k) cleared NIRS (Near-Infrared Spectroscopy) device on neonatal subjects based on data collected from the cutaneously placed…
- Trial name
- NCT03828487
- Testing
- Masimo O3 Neonatal Sensors, 510(k) cleared sensor
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Masimo Corporation
Healthy
Validation of Brain Oxygenation Monitor
A cerebral oximeter is a device that uses light to measure the amount of oxygen within the brain. It is similar to the device that measures the level of oxygen in the tip of the finger, known as a pulse oximeter.
- Trial name
- NCT00815490
- Testing
- Desaturation
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Duke University
Fetal Hypoxia, Fetal Distress
Trans-abdominal Fetal Pulse Oximetry
The Raydiant Oximetry Sensing System (Lumerah) is a non-invasive fetal pulse oximeter that measures fetal arterial oxygen saturation using safe, non-invasive, transabdominal near-infrared spectroscopy.
- Conditions
- Fetal Hypoxia, Fetal Distress, Fetal Acidemia, Fetal or Neonatal Effect of Complication of Labor
- Trial name
- NCT05147584
- Testing
- Dual fetal oxygen sensors
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Raydiant Oximetry, Inc.
Bronchiolitis, Hypoxia
Intermittent Versus Continuous Pulse Oximetry Monitoring of Infants Admitted for Bronchiolitis
Bronchiolitis is a lower respiratory tract infection (LRTI) syndrome cause by different types of viruses and occurs in young children.
- Trial name
- NCT01014910
- Testing
- Continuous pulse oximetry monitoring, Intermittent pulse oximetry monitoring
- Where
- 4 sites in United States
- Volunteers
- 161 people
- Sponsor
- Children's Mercy Hospital Kansas City
Arterial Disease
Vital USA SpO2 Accuracy Comparison to Arterial Blood CO-Oximetry
Clinical Investigation Plan: Vital USA SpO2 Accuracy Comparison to Arterial Blood CO-Oximetry Study ID# PR 2019-353, Version: Rev 1, Date: 15 Oct 2019 Study Dates: November 4-5, 2019
- Trial name
- NCT04285411
- Testing
- Accuracy of the VitalDetect™ pulse oximetry system
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Vital USA, Inc.
Obstructive Sleep Apnea
Oxygen Saturation Patterns in Post-Op Patients at Risk for Obstructive Sleep Apnea
This study will include patients who have major surgery and are at risk for or have been diagnosed with sleep apnea. The patients will be monitored the night after surgery for repeating episodes of reduced breathing and oxygen…
- Trial name
- NCT01078207
- Where
- 2 sites in Canada
- Volunteers
- 100 people
- Sponsor
- Medtronic - MITG
Surgery
Calibration and Validation of Masimo's O3 Regional Oximetry Device in Neonates, Infants and Children
The study will collect cerebral oximetry data from pediatric and neonatal subjects using the Masimo O3 regional oximetry device, for the purposes of device calibration and validation.
- Trial name
- NCT03123354
- Testing
- O3 regional oximeter sensor
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Masimo Corporation
Healthy Subjects
Safety and Efficacy of Trans Sodium Crocetinate (TSC) in Enhancing Tissue Oxygen Levels in Healthy Volunteers
Randomized, double-blind, placebo-controlled, pharmacokinetic, pharmacodynamic study. Subjects will be randomized to TSC or placebo to determine the effect of Trans Sodium Crocetinate (TSC) on Transcutaneous Oximetry Measurements…
- Trial name
- NCT04808622
- Testing
- Trans-Sodium Crocetinate
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Diffusion Pharmaceuticals Inc
Hypoxia
Cerebral Oximetry in Single Lung Ventilation Thoracic Surgery
This is a prospective, randomized controlled pilot study of cerebral oximetry use in elderly patients undergoing thoracic surgical procedures that require the use of single lung ventilation.
- Trial name
- NCT01866657
- Testing
- Vasoconstrictor Agents, Head/neck repositioning, Increase ETCO2
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- University Hospitals Cleveland Medical Center
Post-Op Complication, Skin Flap Necrosis
Quantifying the Venous Congestion Curve of a Tissue Oximetry Device
The purpose of this research study is to measure rate of decline and pattern of tissue oxygenation using the device, ViOptix T.Ox. ViOptix probes will be secured to the arm and hand.
- Trial name
- NCT05592145
- Testing
- ViOptix
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Respiratory Disease, Asthma in Children
Utility of Continuous Pulse Oximetry for Pediatric Patients With Stable Respiratory Illness
This is a randomized, prospective study to determine if there is a difference in hospital length of stay between patients receiving continuous hardwire cardiorespiratory monitoring and those receiving intermittent vital signs…
- Conditions
- Respiratory Disease, Asthma in Children, Pneumonia in Children, Bronchiolitis Acute
- Trial name
- NCT04407806
- Testing
- Continous Pulse oximeter, Intermittent Pulse oximeter
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Corewell Health East
Primary Open Angle Glaucoma
Effect of Travoprost 0.004% on Retinal Oximetry in Primary Open Angle Glaucoma
Glaucoma is the second leading cause of blindness among seniors in Canada. It is often associated with an elevated intraocular pressure (IOP), but its exact mechanism is still largely unknown.
- Trial name
- NCT01711177
- Testing
- travoprost
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Université de Montréal
Hypotension, Pressure Ulcer
Comparison of Nasal and Forehead Oximetry in Critically Ill Patients at Risk for Decreased Peripheral Perfusion
Continuous pulse oximetry monitoring is the standard of care in critically ill patients in emergency departments, operating rooms and intensive care units.
- Trial name
- NCT02382133
- Testing
- Nasal alar oxygen sensor
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Washington University School of Medicine
Sleep Disordered Breathing
Oxygen Monitoring of Patients After Surgery on the Hospital General Care Floor
The pain medication given after major surgery may cause some patients to stop breathing for periods of time especially at night time. An oxygen monitor may reflect this abnormal breathing pattern.
- Trial name
- NCT01082575
- Testing
- Oxygen Monitoring
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- Medtronic - MITG
Surgery
Validation of Noninvasive Hemoglobin, Comparison of PVI to Standard Methods, and Validation of Clinical Efficacy of ORI
The study goal is to establish the correlation of hemoglobin values determined by the noninvasive pulse oximetry-determined hemoglobin (SpHb) system with hemoglobin as measured by other validated devices.
- Trial name
- NCT02841397
- Testing
- Masimo Pulse CO-Oximeter
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Masimo Corporation
Hypoxia
SpO2 Accuracy Comparison of Smart Sock V. 2 SpO2 to Arterial Blood CO-Oximetry
Pulse oximetry monitoring is considered a standard physiological measurement and is used by clinicians in everyday situations to estimate arterial oxygen saturation.
- Trial name
- NCT03630016
- Testing
- Pulse oximetry with Owlet BabySat v1.0 sensor
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Owlet Baby Care, Inc.
Stroke
Correlating Brain Tissue Oxygen and Regional Cerebral Oximetry
Controversy surrounds the use of regional cerebral oximetry (rSO2) as a measure of true cerebral oxygenation because of extracranial signal contamination and unmeasured confounding of cerebral a:v ratio.
- Trial name
- NCT03128957
- Testing
- IVOS cerebral oximeter, Licox cerebral oxygenation monitor, Cerebral oxygenation
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Michigan
Surgery, Arterial Catheterization, Peripheral
Feasibility of Obtaining Pulse Oximetry Readings From the Oropharynx
This is a prospective study to evaluate the feasibility of obtaining a pulse oximetry ready from the oropharynx with a standard oximeter probe that has been attached to an oral airway or a tongue blade.
- Trial name
- NCT05690633
- Testing
- Pulse oximetry
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Joseph D. Tobias
Oximetry
Accuracy of ScanWatch Pulse Oximeter With Profound Hypoxia
Performance testing of pulse oximeters. The protocol involves brief stable arterial oxygen desaturation in healthy volunteers and sampling arterial blood when a stable level of hypoxia has been attained.
- Trial name
- NCT04380389
- Testing
- hypoxia
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Withings
Pulse Oximetry
U-TruSignal SpO2 Testing in Neonates
The purpose of the study is to demonstrate proper function of the U-TruSignal device via clinical performance testing in a neonatal human subject population under standard clinical conditions.
- Trial name
- NCT03383757
- Testing
- SpO2 Sensor application & blood draw
- Where
- 2 sites in Finland, India
- Volunteers
- 117 people
- Sponsor
- GE Healthcare