Clinical trials: Oxygen Disorders
Acute Hypoxic Respiratory Failure, Acute Respiratory Distress Syndrome (ARDS)
WIN Ratio Analysis to Determine a Strategy of Non- Invasive SUpport for Respiratory Failure in the EmeRgency Department
The purpose of this clinical trial is to determine the best initial non-invasive respiratory support (NIRS) strategy for adults who present to the emergency department with acute hypoxemic respiratory failure, a condition in…
- Trial name
- WINDSURFER (NCT07558265)
- Testing
- Non-Invasive Positive Pressure Ventilation, High Flow Nasal Oxygen
- Where
- 6 sites in United States
- Volunteers
- 500 people
- Sponsor
- Ohio State University
Focus: Healthy Adults Without Brain Injury
Normative Datasets for Assessments Planned for Mild Traumatic Brain Injury (NORMAL)
The purpose of the research study is to collect information about brain function and structure among active duty military personnel or civilians who are healthy.
- Trial name
- NORMAL (NCT01925963)
- Where
- 2 sites in United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Lindell Weaver
Acute Respiratory Failure, Hypoxemic Respiratory Failure
Standard Oxygen Versus High Flow Nasal Cannula Oxygen Therapy in Patients With Acute Hypoxemic Respiratory Failure
First-line therapy of patients with acute respiratory failure consists in oxygen delivery through standard oxygen, high-flow nasal oxygen therapy through cannula or non-invasive ventilation.
- Trial name
- SOHO (NCT04468126)
- Testing
- Standard oxygen, High-flow nasal oxygen therapy
- Where
- France
- Volunteers
- 1,504 people
- Sponsor
- Poitiers University Hospital
COVID19, Diabetes Mellitus
Effect of a NSS to Reduce Complications in Patients With Covid-19 and Comorbidities in Stage III
The disease caused by SARS-CoV-2, has derived a pandemic in which its evolution and complications depend on the immune capacity of the host.
- Conditions
- COVID19, Diabetes Mellitus, Hypertension, Obesity
- Trial name
- NCT04507867
- Testing
- Nutritional support system (NSS), Conventional nutritional support designed by hospital nutritionists
- Where
- Mexico
- Volunteers
- 80 people
- Sponsor
- Anahuac University
Pulmonary Fibrosis, Pulmonary Hypertension
Expanded Access for Patients With Pulmonary Hypertension Associated With Pulmonary Fibrosis
An expanded access program that provides INOpulse treatment to patients with serious disease or conditions associated with pulmonary hypertension associated with pulmonary fibrosis who are not able to participate in the Sponsor's…
- Trial name
- NCT05356052
- Testing
- INOpulse
- Sponsor
- Bellerophon
Cardiovascular Diseases, Postoperative Complications
Effects of Cerebral Oxygen Saturation on Neuropsychological Outcomes
The purpose of this study is to evaluate the effects of maintaining adequate cerebral oxygen saturation (over 40%) on patients undergoing cardiac surgery.
- Trial name
- NCT00151307
- Testing
- INVOS cerebral oximeter
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Weill Medical College of Cornell University
Heart Failure.
The Increase Study. Effect of Incremental Versus Fixed Pump on Peak Oxygen Consumption in Heart Failure Patients Supported With a Continuous Flow Left Venticular Assist Device
The purpose of the study is to examine the relationship between working capacity (peak oxygen consumption) and pump speed of continuous flow left ventricular assist devices (CF-LVADs)in heart failure patients.
- Trial name
- NCT01698398
- Testing
- Incremental pump speed of CF-LVAD.
- Where
- Denmark
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Chronic Respiratory Failure
Fibroblast Growth Factor 23 in Chronic Respiratory Failure
Fibroblast growth factor 23 (FGF23) is a key hormone of the mineral metabolism produced in bone and acting on the kidney to lower phosphatemia.
- Trial name
- EFIC-RES (NCT05258370)
- Testing
- Dosage, Cardiac echography
- Volunteers
- 50 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Respiratory Distress Syndrome, Lower Respiratory Tract Infection
A Low-Resource Oxygen Blender Prototype for Use in Modified Bubble CPAP Circuits
Purpose: Using a novel oxygen blender prototype with modified bCPAP to manage children 1 month to 5 years of age hospitalized with respiratory distress due to lower respiratory tract infection (LRTI) in low-resource settings is…
- Trial name
- NCT04311320
- Testing
- Low-Resource Oxygen Blender
- Where
- Cambodia
- Volunteers
- 33 people
- Sponsor
- University of Minnesota
Cardiomyopathy, Hypertrophic
Study of Exercise Training in Hypertrophic Cardiomyopathy
The investigators propose a pilot randomized controlled trial to determine the safety and potential benefits of moderate intensity exercise in patients with hypertrophic cardiomyopathy.
- Trial name
- RESET-HCM (NCT01127061)
- Testing
- Exercise training
- Where
- 2 sites in United States
- Volunteers
- 136 people
- Sponsor
- University of Michigan
Interstitial Lung Disease (ILD)
Nasal High-flow Oxygen Therapy During Rehabilitive Exercise Training in ILD
Although uncommon, interstitial lung diseases (ILDs), and particularly idiopathic pulmonary fibrosis (IPF), are progressive, irreversible, and ultimately fatal without treatment.
- Trial name
- PID-OX (NCT07679854)
- Testing
- Pulmonary rehabilitation with NHFO2, Pulmonary rehabiltation with conventional oxygen therapy
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Frédéric Hérengt
Acute Hypoxemic Respiratory Failure
Physiological Effects of Continuous Negative External Pressure for Acute Hypoxemic Respiratory Failure
This study is being conducted to evaluate if wearing a non-invasive breathing support device over the chest/abdomen improves markers of breathing in patients with lung injury requiring high-flow oxygen.
- Trial name
- NCT05675345
- Testing
- HFNC only, HFNC + CNEP10, HFNC + CNEP20
- Where
- 4 sites in United States
- Volunteers
- 20 people
- Sponsor
- NYU Langone Health
Cardiovascular Diseases
Cardiac Rehabilitation Program in Patients with Cardiovascular Disease
This protocol study aims to evaluate the effectiveness of a cardiac rehabilitation intervention program in patients with cardiovascular diseases to improve both anthropometric and biochemical data, as well as other variables…
- Trial name
- NCT06211361
- Testing
- Cardiac rehabilitation
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- University of Castilla-La Mancha
Lower Respiratory Tract Infection
The Effect of a Family-Centered Care Approach on Infants Receiving High-Flow Nasal Oxygen Therapy
This research is an experimental study of randomized control with pre-test - post-test control group. The aim of this study is to determine the effect of family-centered care approach on physiological parameters and follow-up…
- Trial name
- NCT07183553
- Testing
- maintenance training
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara Etlik City Hospital
Nursing Care
Effect of Diluted Thyme Honey On Dry Mouth In Intensive Care Unit Patients Exposed to Oxygen Flow Therapy
This research is a randomized, controlled, double-blind, experimental study conducted to investigate the effect of diluted thyme honey on dry mouth in individuals receiving treatment in intensive care and receiving nasal oxygen…
- Trial name
- NCT07358494
- Testing
- diluted thyme honey arm, Mouth wash
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Esra Yaprak Gokturk
Brain Injury, Sequelae
Hyperbaric Oxygen Therapy in Chronic Stable Brain Injury
The purpose of this study is to discover the feasibility of conducting clinical research in individuals with chronic sequelae following brain injury who are given hyperbaric oxygen.
- Conditions
- Brain Injury, Sequelae, Stroke, Anoxia
- Trial name
- HYBOBI (NCT00830453)
- Testing
- Hyperbaric oxygen therapy (HBO2)
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Intermountain Health Care, Inc.
Postoperative Complications, Orthopedic Disorder
PaO2 and Lung Function After Orthopedic Surgery
Hypoxia and reduced oxygen partial pressure is commonly occurring after abdominal surgery. This study aims to investigate whether similar changes also occur after orthopedic surgery in the form of upper limb surgery.
- Trial name
- NCT05227573
- Testing
- Orthopedic surgery
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Umeå University
Arteriosclerosis, Coronary
Aquatic Aerobic Training, Cardiorespiratory and Metabolic Variables in Coronary Artery Disease
Although approaches to reduce cardiovascular disease, coronary artery disease (CAD) remains the leading cause of mortality in the industrialized world.
- Trial name
- NCT02211573
- Testing
- Exercise, Aerobic (Water based)
- Where
- Brazil
- Volunteers
- 21 people
- Sponsor
- Universidade Metodista de Piracicaba
Normative Oxygen Saturation Data Will Help us in, Discharge Planning
Trends In Oxygen Saturation In Healthy Term Infants In The First Few Days Of Life: The "TOST" Study
Oxygen is carried in the blood attached to hemoglobin molecules. Oxygen saturation is a measure of how much oxygen hemoglobin is carrying as a percentage of the maximum it could carry.
- Conditions
- Normative Oxygen Saturation Data Will Help us in, Discharge Planning, Describing Guidelines for Pulse Oximetry Screening, Identification of High Risk Infants
- Trial name
- NCT02095041
- Where
- 4 sites in Canada
- Volunteers
- 293 people
- Sponsor
- University of Calgary
Cystic Fibrosis
Non-invasive Ventilation and Oxygen Therapy in Cystic Fibrosis Patients With Nocturnal Oxygen Desaturation
The purpose of this study is to determine whether correction of low nighttime oxygen (O2) levels and/ or high carbon dioxide levels in patients with cystic fibrosis improves their quality of life.
- Trial name
- NCT00157183
- Testing
- Nocturnal oxygen , nocturnal bi-level positive pressure ventilation
- Where
- Australia
- Volunteers
- 59 people
- Sponsor
- Bayside Health
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