Nursing CareNCT07358494
Effect of Diluted Thyme Honey On Dry Mouth In Intensive Care Unit Patients Exposed to Oxygen Flow Therapy
A study testing diluted thyme honey arm and Mouth wash in people with Nursing Care, run by Esra Yaprak Gokturk at 1 site in Turkey (Türkiye).
Trial summary
This research is a randomized, controlled, double-blind, experimental study conducted to investigate the effect of diluted thyme honey on dry mouth in individuals receiving treatment in intensive care and receiving nasal oxygen flow therapy. Read more about this study
- Who is it for?
- Any age
- Conditions the study is for
- Nursing Care
- What is being tested?
- diluted thyme honey arm and Mouth wash
- Type of treatment
- Pill or oral medicine
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 64 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 1 Oct 2022to 30 Nov 2022
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- All sexes
- No healthy volunteers
- Child, Adult, Older adult
Who may be able to join
- Being treated under intensive care conditions and receiving nasal oxygen flow therapy above 4L/min,
- Over 18 years of age,
- Not diagnosed with Sjögren's Syndrome,
- No previous exposure to radiotherapy or chemotherapy,
- Has not had a salivary gland infection,
- Has not undergone an operation to remove the salivary glands,
Show all 10Show fewer
- Not allergic to honey,
- No chewing or swallowing difficulties,
- Not using thyme-containing products for oral care in the previous period,
- Patients who did not have any communication problems and who voluntarily agreed to participate in the study were included in the study
Who cannot join
- Patients who did not meet the inclusion criteria and did not voluntarily agree to participate in the study were excluded.
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Ankara University Institute of Health Sciences Department of Nursing
Ankara, Dışkapı, 6070
About this study
Official title: Effect of Diluted Thyme Honey On Dry Mouth In Intensive Care Unit Patients Exposed to Oxygen Flow Therapy: A Randomized Controlled Study
This research is a randomized, controlled, double-blind, experimental study conducted to investigate the effect of diluted thyme honey on dry mouth in individuals receiving treatment in intensive care and receiving nasal oxygen flow therapy.
H0: There is no significant difference in reducing dry mouth in intensive care patients receiving nasal oxygen flow therapy between the intervention group receiving oral care with diluted thyme honey and the control group receiving standard oral care.
The study sample consisted of 64 inpatients receiving nasal oxygen flow therapy in the Emergency Intensive Care and Emergency Critical Intensive Care Units of Ankara Training and Research Hospital. Patients were divided into groups using a sealed envelope method. Patients in the intervention group received oral care using diluted thyme honey, while patients in the control group received oral care using 0.9% NaCl.
Read the detailed description
SUMMARY
Backround Dry mouth due to nasal oxygen flow therapy is one of the side effects frequently experienced by patients treated in intensive care units. Although there are various pharmacological and complementary medicine methods for the prevention and treatment of dry mouth, this condition continues to negatively affect the daily lives of patients due to the lack of a definitive method and the neglect of oral care.
Aim The aim of this study was to evaluate the efficacy of diluted thyme honey in preventing dry mouth in intensive care patients receiving nasal oxygen flow therapy.
Desing This study has a randomized controlled experimental design.
Methods This study included 64 intensive care unit patients receiving nasal oxygen flow therapy. It was a randomized controlled experimental study consisting of intervention (thyme honey) and control group (0.9% NaCl). Participants were randomized to the groups by closed envelope method. 32 patients were included in both groups. Patients in both groups included in the study underwent the same protocol steps except for the oral care product (thyme honey and 0.9% NaCl). After obtaining consent from the patients who agreed to be included in the study, information about the participants was collected by asking the Patient Information Form prepared by the researcher. The Subjective Dry Mouth Form was administered to the participants before the start of the study and at the end of the 3rd day when the application protocols were completed. After the applications were completed, the pre-test and post-test scores of the patients in response to each question in the 'Subjective Dry Mouth Evaluation Form' and their answers to an open-ended question about their opinions on thyme honey in the Patient Information Form were combined in the patient follow-up form.
- Conditions
- Nursing Care
- Being tested
- diluted thyme honey arm, Mouth wash
- Keywords
- Xerostomia, Thyme Honey, Nursing, Nasal Oxygen Flow Treatment
- Medical subject headings
- Xerostomia
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
diluted thyme honey armOther
In this study, the feasibility of an alternative method for alleviating dry mouth, which is very important in terms of nursing care, was investigated. The effect of diluted thyme honey, which had not been previously studied, on dry mouth was investigated in intensive care patients receiving nasal oxygen flow therapy in the intervention group. The control group received oral care using a standard oral care solution of 0.9% NaCl.
Mouth washOther
In this study, the usability of an alternative method for the elimination of dry mouth, which has a very important place in terms of nursing care, was investigated. The effect of diluted thyme honey on dry mouth in intensive care patients receiving nasal oxygen flow therapy, which has not been previously studied in the literature, was investigated.
| Study group | Role | What they receive |
|---|---|---|
| diluted thyme honey arm | Experimental | * After obtaining informed consent from participants who agreed to participate in the study, they were asked to draw one sealed envelope from a bag containing sealed envelopes numbered from 1 to 64. The envelopes drawn by the patients were opened in their presence. The researcher determined whether the patients would be included in the intervention or control group based on the number drawn from the envelope.
* Participants assigned to the intervention group were first given the Patient Information Form. Then, before starting the intervention, participants were asked questions from the "Subjective Dry Mouth Assessment Form" prepared by Duruk (2012) using the Visual Analogue Scale. Each point given in response to the questions was recorded in the Patient Follow-up Form.
* Patients were educated on the importance of dry mouth, the types of foods and liquids to avoid, the necessity of adequate saliva secretion, the functions of saliva, methods of coping with dry mouth, and the necess Receives: Other: diluted thyme honey arm; Other: Mouth wash |
| 0.9% NaCl arm | Placebo comparator | After obtaining informed consent from participants who agreed to participate in the study, they were asked to draw one sealed envelope from a bag containing sealed envelopes with numbers ranging from 1 to 64 written on them. The envelopes drawn by the patients were opened in their presence. Patients were assigned to either the intervention or control group according to the number drawn from the envelope.
* Participants in the control group were first given the Patient Information Form. Then, before starting the application, they were asked questions from the Subjective Dry Mouth Assessment Form. Each point given in response to the questions was recorded in the Patient Follow-up Form.
* Patients were educated on the importance of dry mouth, the types of foods and liquids to avoid, the necessity of adequate saliva secretion, the functions of saliva, methods for coping with dry mouth, and the necessary precautions to identify and report any side effects that Receives: Other: Mouth wash |
What is being measured
The primary outcome is the main question the study is designed to answer.
The Effect of Diluted Thyme Honey on Dry Mouth in Intensive Care Patients Receiving Nasal Oxygen Flow Therapy: A Randomized Controlled Trial
The Subjective Dry Mouth Assessment Form was used to assess dry mouth. This form includes questions regarding symptoms such as "dry mouth," "difficulty swallowing," "difficulty speaking," "waking up from sleep," "dry tongue," "burning mouth," "burning throat," "dry throat," "thirst," "bad taste in the mouth," "saliva volume," and "bad breath." Responses are scored on a 0-10 scale using 11 Visual Analogue Scales (VAS). Scoring begins with 0 (not at all) and ends with 10 (extremely).
The Subjective Dry Mouth Assessment Form was administered to patients before the study began to gather patient information and determine their dry mouth levels. At the end of the third day, the Subjective Dry Mouth Assessment Form was administered to the patients, who underwent three days of treatment, and their dry mouth was re-evaluated. Data on the patients' dry mouth levels were collected before and after the study.
Measured: 9 week
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted22 Jan 2026
- Study start1 Oct 2022
- Primary completion30 Nov 2022
- Study completion30 Nov 2022
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (35)Papers the sponsor has linked to this study.
- Other trials for Nursing CareStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- This study has a randomized controlled experimental design.
- Masking
- Double blind
- Who is masked
- Participant, Care provider
- Enrolment
- 64 participants (actual)
Sponsor and investigators
- Lead sponsor
- Esra Yaprak Gokturk
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor-investigator, Esra Yaprak Gokturk, Ankara University
- Investigators
- ayten demir, assoc.prof.dr., Study director, Ankara University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07358494
- Sponsor's protocol ID
- AnkaraU-esrayaprakgokturk01
- Status last verified
- Jan 2026
- First submitted
- 21 May 2025
- Last updated
- 22 Jan 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes
Publications
YAVUZ KARAMANOĞLU A, YAVUZ M (2015). Ağız Sağlığı Hemşirelik Değerlendirmesinde Kanıtlar Ve Uygulama Önerileri. Ege Üniversitesi Hemşirelik Fakültesi Dergisi, 31(1): 131-143.
Takzaree N, Hassanzadeh G, Rouini MR, Manayi A, Hadjiakhondi A, Majidi Zolbin M. Evaluation of the Effects of Local Application of Thyme Honey in Open Cutaneous Wound Healing. Iran J Public Health. 2017 Apr;46(4):545-551.
PubMed 28540272TABACHNICK B G, FIDELL L S, (2013). Using multivariate statistics. Boston:Pearson. 6: 497-516.
SEO E, SONG J, HUR M, LEE M, SOO LEE M (2017). Effects of aroma mouthwash on stress level, xerostomia, and halitosis in healthy nurses: A non-randomized controlled clinical trial. European Journal of Integrative Medicine, 10: 82-89. DOI: 10.1016/j.eujim.2017.03.001
ÖZKÖK A, KORU Ö, SORKUN K (2016). Microbiological Analysis And Antibacterial Effects Of Turkish Thyme Honey. Bee World, 93(4): 98-101. DOI: 10.1080/0005772X.2016.1275489
Lopez-Pintor RM, Casanas E, Gonzalez-Serrano J, Serrano J, Ramirez L, de Arriba L, Hernandez G. Xerostomia, Hyposalivation, and Salivary Flow in Diabetes Patients. J Diabetes Res. 2016;2016:4372852. doi: 10.1155/2016/4372852. Epub 2016 Jul 10.
PubMed 27478847Li Y, Taylor JM, Ten Haken RK, Eisbruch A. The impact of dose on parotid salivary recovery in head and neck cancer patients treated with radiation therapy. Int J Radiat Oncol Biol Phys. 2007 Mar 1;67(3):660-9. doi: 10.1016/j.ijrobp.2006.09.021. Epub 2006 Dec 4.
PubMed 17141973Lagerlof F, Dawes C. The volume of saliva in the mouth before and after swallowing. J Dent Res. 1984 May;63(5):618-21. doi: 10.1177/00220345840630050201.
PubMed 6584462Lafraxo H, Bakour M, Laaroussi H, El Ghouizi A, Ousaaid D, Aboulghazi A, Lyoussi B. The Synergistic Beneficial Effect of Thyme Honey and Olive Oil against Diabetes and Its Complications Induced by Alloxan in Wistar Rats. Evid Based Complement Alternat Med. 2021 Sep 20;2021:9949056. doi: 10.1155/2021/9949056. eCollection 2021.
PubMed 34594393Konings AW, Coppes RP, Vissink A. On the mechanism of salivary gland radiosensitivity. Int J Radiat Oncol Biol Phys. 2005 Jul 15;62(4):1187-94. doi: 10.1016/j.ijrobp.2004.12.051.
PubMed 15990024Kobya Bulut H, Guducu Tufekci F. Honey prevents oral mocositis in children undergoing chemotherapy: A quasi-experimental study with a control group. Complement Ther Med. 2016 Dec;29:132-140. doi: 10.1016/j.ctim.2016.09.018. Epub 2016 Sep 19.
PubMed 27912937KILAVUZ, DERVİŞ KAAN (2014). Türk Toplumunda Ağız Kuruluğu Prevalansının Araştırılması. Doktora Tezi, Gazi Üniversitesi.
Kannarkat G, Lasher EE, Schiff D. Neurologic complications of chemotherapy agents. Curr Opin Neurol. 2007 Dec;20(6):719-25. doi: 10.1097/WCO.0b013e3282f1a06e.
PubMed 17992096Hashemian F, Baghbanian N, Majd Z, Rouini MR, Jahanshahi J, Hashemian F. The effect of thyme honey nasal spray on chronic rhinosinusitis: a double-blind randomized controlled clinical trial. Eur Arch Otorhinolaryngol. 2015 Jun;272(6):1429-35. doi: 10.1007/s00405-014-3233-x. Epub 2014 Aug 9.
PubMed 25106547Hanchanale S, Adkinson L, Daniel S, Fleming M, Oxberry SG. Systematic literature review: xerostomia in advanced cancer patients. Support Care Cancer. 2015 Mar;23(3):881-8. doi: 10.1007/s00520-014-2477-8. Epub 2014 Oct 18.
PubMed 25322971
Study at a glance
From the registry record, last updated by the sponsor on 22 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of Diluted Thyme Honey On Dry Mouth In Intensive Care Unit Patients Exposed to Oxygen Flow Therapy: A Randomized Controlled Study
- ClinicalTrials.gov ID
- NCT07358494
- Acronym / sponsor ID
- AnkaraU-esrayaprakgokturk01
- Conditions
- Nursing Care
- Keywords
- Xerostomia, Thyme Honey, Nursing, Nasal Oxygen Flow Treatment
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 64 participants (actual)
- Lead sponsor
- Esra Yaprak GokturkUniversity, hospital or other
- Study start
- 1 Oct 2022 (actual)
- Primary completion
- 30 Nov 2022 (actual)
- Study completion
- 30 Nov 2022 (actual)
- First posted
- 22 Jan 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This research is a randomized, controlled, double-blind, experimental study conducted to investigate the effect of diluted thyme honey on dry mouth in individuals receiving treatment in intensive care and receiving nasal oxygen flow therapy.
H0: There is no significant difference in reducing dry mouth in intensive care patients receiving nasal oxygen flow therapy between the intervention group receiving oral care with diluted thyme honey and the control group receiving standard oral care.
The study sample consisted of 64 inpatients receiving nasal oxygen flow therapy in the Emergency Intensive Care and Emergency Critical Intensive Care Units of Ankara Training and Research Hospital. Patients were divided into groups using a sealed envelope method. Patients in the intervention group received oral care using diluted thyme honey, while patients in the control group received oral care using 0.9% NaCl.
Detailed description
SUMMARY
Backround Dry mouth due to nasal oxygen flow therapy is one of the side effects frequently experienced by patients treated in intensive care units. Although there are various pharmacological and complementary medicine methods for the prevention and treatment of dry mouth, this condition continues to negatively affect the daily lives of patients due to the lack of a definitive method and the neglect of oral care.
Aim The aim of this study was to evaluate the efficacy of diluted thyme honey in preventing dry mouth in intensive care patients receiving nasal oxygen flow therapy.
Desing This study has a randomized controlled experimental design.
Methods This study included 64 intensive care unit patients receiving nasal oxygen flow therapy. It was a randomized controlled experimental study consisting of intervention (thyme honey) and control group (0.9% NaCl). Participants were randomized to the groups by closed envelope method. 32 patients were included in both groups. Patients in both groups included in the study underwent the same protocol steps except for the oral care product (thyme honey and 0.9% NaCl). After obtaining consent from the patients who agreed to be included in the study, information about the participants was collected by asking the Patient Information Form prepared by the researcher. The Subjective Dry Mouth Form was administered to the participants before the start of the study and at the end of the 3rd day when the application protocols were completed. After the applications were completed, the pre-test and post-test scores of the patients in response to each question in the 'Subjective Dry Mouth Evaluation Form' and their answers to an open-ended question about their opinions on thyme honey in the Patient Information Form were combined in the patient follow-up form.
Study design
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, care provider)
- Number of arms
- 2
- Model description
- This study has a randomized controlled experimental design.
| Arm | Type | Receives |
|---|---|---|
| diluted thyme honey arm | Experimental | Other: diluted thyme honey arm, Other: Mouth wash* After obtaining informed consent from participants who agreed to participate in the study, they were asked to draw one sealed envelope from a bag containing sealed envelopes numbered from 1 to 64. The envelopes drawn by the patients were opened in their presence. The researcher determined whether the patients would be included in the intervention or control group based on the number drawn from the envelope. * Participants assigned to the intervention group were first given the Patient Information Form. Then, before starting the intervention, participants were asked questions from the "Subjective Dry Mouth Assessment Form" prepared by Duruk (2012) using the Visual Analogue Scale. Each point given in response to the questions was recorded in the Patient Follow-up Form. * Patients were educated on the importance of dry mouth, the types of foods and liquids to avoid, the necessity of adequate saliva secretion, the functions of saliva, methods of coping with dry mouth, and the necess |
| 0.9% NaCl arm | Placebo comparator | Other: Mouth washAfter obtaining informed consent from participants who agreed to participate in the study, they were asked to draw one sealed envelope from a bag containing sealed envelopes with numbers ranging from 1 to 64 written on them. The envelopes drawn by the patients were opened in their presence. Patients were assigned to either the intervention or control group according to the number drawn from the envelope. * Participants in the control group were first given the Patient Information Form. Then, before starting the application, they were asked questions from the Subjective Dry Mouth Assessment Form. Each point given in response to the questions was recorded in the Patient Follow-up Form. * Patients were educated on the importance of dry mouth, the types of foods and liquids to avoid, the necessity of adequate saliva secretion, the functions of saliva, methods for coping with dry mouth, and the necessary precautions to identify and report any side effects that |
Who may qualify
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult, Older adult
Key inclusion criteria (10 listed)
- Being treated under intensive care conditions and receiving nasal oxygen flow therapy above 4L/min,
- Over 18 years of age,
- Not diagnosed with Sjögren's Syndrome,
- No previous exposure to radiotherapy or chemotherapy,
- Has not had a salivary gland infection,
Key exclusion criteria (1 listed)
- Patients who did not meet the inclusion criteria and did not voluntarily agree to participate in the study were excluded.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| diluted thyme honey armIn this study, the feasibility of an alternative method for alleviating dry mouth, which is very important in terms of nursing care, was investigated. The effect of diluted thyme honey, which had not been previously studied, on dry mouth was investigated in intensive care patients receiving nasal oxygen flow therapy in the intervention group. The control group received oral care using a standard oral care solution of 0.9% NaCl. | Other | diluted thyme honey arm |
| Mouth washIn this study, the usability of an alternative method for the elimination of dry mouth, which has a very important place in terms of nursing care, was investigated. The effect of diluted thyme honey on dry mouth in intensive care patients receiving nasal oxygen flow therapy, which has not been previously studied in the literature, was investigated. | Other | 0.9% NaCl arm, diluted thyme honey arm |
Primary outcome
The Effect of Diluted Thyme Honey on Dry Mouth in Intensive Care Patients Receiving Nasal Oxygen Flow Therapy: A Randomized Controlled Trial
Time frame: 9 week
The Subjective Dry Mouth Assessment Form was used to assess dry mouth. This form includes questions regarding symptoms such as "dry mouth," "difficulty swallowing," "difficulty speaking," "waking up from sleep," "dry tongue," "burning mouth," "burning throat," "dry throat," "thirst," "bad taste in the mouth," "saliva volume," and "bad breath." Responses are scored on a 0-10 scale using 11 Visual Analogue Scales (VAS). Scoring begins with 0 (not at all) and ends with 10 (extremely). The Subjective Dry Mouth Assessment Form was administered to patients before the study began to gather patient information and determine their dry mouth levels. At the end of the third day, the Subjective Dry Mouth Assessment Form was administered to the patients, who underwent three days of treatment, and their dry mouth was re-evaluated. Data on the patients' dry mouth levels were collected before and after the study.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 22 Jan 2026.
- Results publicationYAVUZ KARAMANOĞLU A, YAVUZ M (2015). Ağız Sağlığı Hemşirelik Değerlendirmesinde Kanıtlar Ve Uygulama Önerileri. Ege Üniversitesi Hemşirelik Fakültesi Dergisi, 31(1): 131-143.
- Results publication: PubMed 28540272Takzaree N, Hassanzadeh G, Rouini MR, Manayi A, Hadjiakhondi A, Majidi Zolbin M. Evaluation of the Effects of Local Application of Thyme Honey in Open Cutaneous Wound Healing. Iran J Public Health. 2017 Apr;46(4):545-551.
- Results publicationTABACHNICK B G, FIDELL L S, (2013). Using multivariate statistics. Boston:Pearson. 6: 497-516.
- Results publicationSEO E, SONG J, HUR M, LEE M, SOO LEE M (2017). Effects of aroma mouthwash on stress level, xerostomia, and halitosis in healthy nurses: A non-randomized controlled clinical trial. European Journal of Integrative Medicine, 10: 82-89. DOI: 10.1016/j.eujim.2017.03.001
- Results publicationÖZKÖK A, KORU Ö, SORKUN K (2016). Microbiological Analysis And Antibacterial Effects Of Turkish Thyme Honey. Bee World, 93(4): 98-101. DOI: 10.1080/0005772X.2016.1275489
- Results publication: PubMed 27478847Lopez-Pintor RM, Casanas E, Gonzalez-Serrano J, Serrano J, Ramirez L, de Arriba L, Hernandez G. Xerostomia, Hyposalivation, and Salivary Flow in Diabetes Patients. J Diabetes Res. 2016;2016:4372852. doi: 10.1155/2016/4372852. Epub 2016 Jul 10.
- Results publication: PubMed 17141973Li Y, Taylor JM, Ten Haken RK, Eisbruch A. The impact of dose on parotid salivary recovery in head and neck cancer patients treated with radiation therapy. Int J Radiat Oncol Biol Phys. 2007 Mar 1;67(3):660-9. doi: 10.1016/j.ijrobp.2006.09.021. Epub 2006 Dec 4.
- Results publication: PubMed 6584462Lagerlof F, Dawes C. The volume of saliva in the mouth before and after swallowing. J Dent Res. 1984 May;63(5):618-21. doi: 10.1177/00220345840630050201.
- Results publication: PubMed 34594393Lafraxo H, Bakour M, Laaroussi H, El Ghouizi A, Ousaaid D, Aboulghazi A, Lyoussi B. The Synergistic Beneficial Effect of Thyme Honey and Olive Oil against Diabetes and Its Complications Induced by Alloxan in Wistar Rats. Evid Based Complement Alternat Med. 2021 Sep 20;2021:9949056. doi: 10.1155/2021/9949056. eCollection 2021.
- Results publication: PubMed 15990024Konings AW, Coppes RP, Vissink A. On the mechanism of salivary gland radiosensitivity. Int J Radiat Oncol Biol Phys. 2005 Jul 15;62(4):1187-94. doi: 10.1016/j.ijrobp.2004.12.051.
- Results publication: PubMed 27912937Kobya Bulut H, Guducu Tufekci F. Honey prevents oral mocositis in children undergoing chemotherapy: A quasi-experimental study with a control group. Complement Ther Med. 2016 Dec;29:132-140. doi: 10.1016/j.ctim.2016.09.018. Epub 2016 Sep 19.
- Results publicationKILAVUZ, DERVİŞ KAAN (2014). Türk Toplumunda Ağız Kuruluğu Prevalansının Araştırılması. Doktora Tezi, Gazi Üniversitesi.
- Individual participant dataSharing planned: Yes
Related trials for Nursing Care
Not yet recruiting
The Effectiveness of Comic-based Learning Materials on Nursing Students' Knowledge, Attitudes, and Confidence in Dementia Care
Dementia Care Education, Students, Nursing
Enrolling by invitation
ProFoUND PCC= A Program For a Userbased Nursing Development in Person-Centered Care, is a Project That Aims to Develop, Test and Evaluate Effects of a Co-created Intervention to Increase Person-centred Care in Residential Care Settings for Older People.
To Develop, Test, Implement and Evaluate a Model for Person-centred Care for Older People at Two Academic Residential Care Facilities
Not yet recruitingObservational study
Soap-and-Water Bed Bath Versus Disposable Wipe Bath in the Same ICU Patients
Critical Illness, Pain
Active, not recruiting
This Research Proposal Focuses on Evaluating the Effectiveness of a Nursing Care Protocol in Preventing Deep Vein Thrombosis (DVT) in Patients Undergoing On-pump Cardiac Surgery. The Study Will Include an Intervention Group That Receives the Nursing Protocol and a Control Group That Receives Routine
On-pump Cardiac Surgery - Prevention - Intervention - Experimental Group - Control Group - Incidence - Complications, DVT - Deep Vein Thrombosis
Recruiting
Perioperative Meditation Music Intervention in Patients With Type 2 Diabetes Undergoing Elective Surgery
Diabetes Type 2
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
ayten demir, assoc.prof.dr. study director
Ankara University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing diluted thyme honey arm and Mouth wash in people with Nursing Care, run by Esra Yaprak Gokturk at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 10 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 22 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
The Effect of Diluted Thyme Honey on Dry Mouth in Intensive Care Patients Receiving Nasal Oxygen Flow Therapy: A Randomized Controlled Trial (time frame: 9 week). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07358494, which also lists 35 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 22 Jan 2026.