Clinical trials: Oxygen Disorders
COVID-19, Hypoxemia
Clinical Impact of Automated Oxygen Administration on Confirmed or Suspected COVID-19 in the Emergency Department.
The aim of this study is to evaluate the impact of the FreeO2 system on the quality of the oxygen therapy in confirmed or suspected SARS-CoV-2 patients in the emergency department.
- Conditions
- COVID-19, Hypoxemia, Hyperoxia, Hypoxia
- Trial name
- NCT05235386
- Testing
- Automated oxygen titration
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Laval University
Cardiogenic Shock, Extracorporeal Membrane Oxygenation
Individualized or Conventional Transfusion Strategies During Peripheral VA-ECMO
This multicenter randomized controlled trial compare two transfusion strategies of red blood cells transfusion in patients supported by veno-arterial extracorporeal membrane oxygenation for refractory cardiogenic shock.
- Conditions
- Cardiogenic Shock, Extracorporeal Membrane Oxygenation, Transfusion Related Complication, Anemia
- Trial name
- ICONE (NCT05699005)
- Testing
- Packed Red Blood Cells (PRBCs)
- Where
- 4 sites in France
- Volunteers
- 236 people
- Sponsor
- University Hospital, Lille
Sickle Cell Disease
Prevalence of Problematic Use of Equimolar Mixture of Oxygen and Nitrous Oxide and Analgesics in the Sickle-cell Disease
The use of analgesics can lead to cases of drug abuse and dependence. It can also cause pseudo-addiction in patients suffering from pain.
- Trial name
- PHEDRE (NCT02580565)
- Testing
- telephone interview
- Where
- France
- Volunteers
- 1,004 people
- Sponsor
- Nantes University Hospital
Pulmonary Disease, Chronic Obstructive, Heart Failure
Neuromuscular Fatigue During Exercise in COPD-HF Overlap
Rationale. Chronic obstructive pulmonary disease (COPD) and heart failure (HF) coexist in approximately one third of patients presenting with one of these conditions.
- Trial name
- FIBOX (NCT05235685)
- Testing
- Medical air, Hyperoxia
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Grenoble
Stroke, Hyperbaric Oxygen
Hyperbaric Oxygen in Patients Who Had a Stroke
Prospective clinical assessment of 40 Hyperbaric Oxygen (HBO) treatments in 10 completed stroke patients.
- Trial name
- HOST (NCT04297358)
- Testing
- Hyperbaric oxygen
- Where
- Switzerland
- Volunteers
- 10 people
- Sponsor
- Hyperbaric Center Basel
Cluster Headache
A Pilot Study of Demand Valve Oxygen Inhalation Therapy for Cluster Headache
Cluster headache is a disorder marked by frequent attacks of short-lasting, severe, unilateral head pain with associated autonomic symptoms. It is the most severe head pain syndrome known.
- Trial name
- NCT01298921
- Testing
- Oxygen
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Geisinger Clinic
Cardiac Arrest, Hypoxia
Effectiveness of Chest Compressions Under Mild Hypoxia
The purpose of this study is to evaluate the effect of breathing a slightly reduced amount of oxygen will have on a rescuer's ability to provide chest compressions during CPR.
- Trial name
- NCT04072484
- Testing
- Mild hypoxia
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Retinitis Pigmentosa
Clinical Trials of Continuous Oxygen Therapy Combined With Blue Light Deprivation in the Treatment of Retinitis Pigmentosa
The purpose of this study is to investigate the role of continuous oxygen therapy combined with blue light deprivation in prevention and control of retinitis pigmentosa, in order to find a new strategy of treatment for retinitis…
- Trial name
- NCT02465749
- Testing
- Continuous oxygen, blue light-absorbing sunglasses, Compound thrombosis capsule sig: 1.5g/tid
- Where
- China
- Volunteers
- 404 people
- Sponsor
- Sun Yat-sen University
Chronic Obstructive Pulmonary Disease
Oxygen Therapy Remote Monitoring in COPD Patients.
Background : Long-term oxygen therapy is prescribed for patients with severe COPD. The aim of oxygen therapy is to administer oxygen at a concentration level higher than that of ambient air, in order to treat or prevent the…
- Trial name
- NCT05473780
- Where
- 36 sites in France
- Volunteers
- 159 people
- Sponsor
- Vivisol
Diabetes Mellitus
ELO Water In Diabetes Care For Enhancement Of Blood Sugar Control
This double-blinded, randomised and controlled trial evaluates the efficacy of oxygen-enriched ELO drinking water as an adjuvant modality in diabetes care for enhancement of glycemic control in patients with Type 2 diabetes…
- Trial name
- EDEN (NCT04127890)
- Testing
- ELO Water
- Where
- Singapore
- Volunteers
- 150 people
- Sponsor
- Changi General Hospital
Periodontitis
Clinical Effectiveness of Oxygen-Releasing Oral Gel as an Adjunct to Scaling and Root Debridement in Patients With Severe Periodontal Pockets: A Randomized Clinical Trial
The goal of this clinical trial is to learn if adding an oxygen-releasing gel to a deep dental cleaning treatment can improve gum health more than deep cleaning alone, in adults with severe gum disease.
- Trial name
- NCT07840859
- Testing
- Topical oxygen-releasing oral gel, No intervention
- Where
- Malaysia
- Volunteers
- 38 people
- Sponsor
- Universiti Sains Malaysia
Hypoxemic Respiratory Failure
Impact of High-level Oxygen Therapy on the Reconditioning of Type I Hypoxemic Respiratory Insufficiency Patients in Intensive Care
High-throughput oxygen therapy is known as an alternative to non-invasive ventilation, with a benefit in terms of survival in non-hypercapnic respiratory failure patients.
- Trial name
- NCT04022603
- Testing
- Cyclometer Ergometer
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Dr David DE BELS
Peripheral Arterial Disease
Analysis of Arterial Waveforms and Oxygen Pressure During Supervised Exercise for Peripheral Artery Disease
The goal of this observational study is to assess the evolution of oxygen pressure and arterial waveform during supervised exercise therapy in patients with peripheral arterial disease.
- Trial name
- WAVESUPEX (NCT05818046)
- Testing
- transcutaneous oxygen pressure, Supervised Exercise therapy
- Where
- France
- Volunteers
- 36 people
- Sponsor
- University Hospital, Caen
Post-concussive Symptoms, Traumatic Brain Injury
Hyperbaric Oxygen Therapy (HBO2) for Persistent Post-concussive Symptoms After Mild Traumatic Brain Injury (mTBI)
This is a Phase II randomized trial designed to describe the magnitude of change between baseline and follow-up outcomes for symptom surveys and a battery of neuropsychological tests administered at time points corresponding…
- Trial name
- HOPPS (NCT01306968)
- Testing
- hyperbaric oxygen
- Where
- 5 sites in United States
- Volunteers
- 79 people
- Sponsor
- U.S. Army Medical Research and Development Command
Cardiac Arrest
Relationship Between Tissue Markes in Patients With Post Cardio Respiratory Syndrome
There is a correlation between hospital mortality and changes in markers of tissue perfusion, lactate, and venous oxygen saturation and carbon dioxide gradient.
- Trial name
- NCT01455662
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- Hospital Nossa Senhora da Conceicao
Traumatic Brain Injury, Post-Concussive Symptoms
Long-Term Outcomes Following HBOT
This study is designed to better understand the long-term effects of hyperbaric oxygen therapy (HBOT). Our goal is to determine whether improvements after treatment are maintained over time and whether additional benefits appear…
- Conditions
- Traumatic Brain Injury, Post-Concussive Symptoms, Post-Traumatic Stress Disorder
- Trial name
- NCT07732374
- Testing
- Hyperbaric Oxygen Therapy (HBOT)
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Summit Hyperbarics and Wellness
Spinal Cord Injuries
VO2peak and Exercise Efficiency in Upper-body Poling
This study compares peak oxygen uptake (VO2peak) and exercise efficiency in upper-body poling versus arm crank ergometry in trained able-bodied and paraplegic participants.
- Trial name
- NCT03284086
- Testing
- upper-body double-poling, arm crank ergometry
- Where
- Norway
- Volunteers
- 18 people
- Sponsor
- Norwegian University of Science and Technology
Acute Mountain Sickness
Change in Peripheral Oxygen Saturation by Using Different Breathing Procedures in High Altitude
In this investigation the researchers explore whether different types of breathing procedures can improve the peripheral oxygen saturation to reduce the risk of becoming a acute mountain sickness or a high altitude pulmonary…
- Trial name
- NCT01468194
- Testing
- Breathing procedure 1, Breathing procedure 2
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Giessen
Myocardial Infarction, Cardiopulmonary Disease
The Effect of HIIT, MICT in Patients With Myocardial Infarction
This study will investigate the effect of a 12-weeks cardiac rehabilitation training (HIIT, MICT) program on VO2peak and cardiac fibrosis in patients, and evaluate the effects of HIIT on endothelial function, microvascular…
- Conditions
- Myocardial Infarction, Cardiopulmonary Disease, Training Group, Sensitivity
- Trial name
- NCT04863677
- Testing
- High Intensity Interval Training(HIIT）, Moderate Intensity Continuous Training(MICT）
- Where
- China
- Volunteers
- 188 people
- Sponsor
- Guangdong Provincial People's Hospital
Peripheral Arterial Disease, Critical Limb Ischemia
BOLD MRI as a Surrogate of Improved Muscle Oxygenation Following Endovascular Therapy for the Treatment of CLI
The purpose of this study is to determine if an MRI technique called Blood Oxygen Level Dependent, or BOLD, can be used to evaluate blood flow in the leg before and after treatment with standard endovascular therapy in patients…
- Trial name
- NCT02601430
- Testing
- BOLD-MRI
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Zimmer Biomet
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