Clinical trials: Oxygen Disorders
Pulmonary Disease, Chronic Obstructive, Heart Failure
Neuromuscular Fatigue During Exercise in COPD-HF Overlap
Rationale. Chronic obstructive pulmonary disease (COPD) and heart failure (HF) coexist in approximately one third of patients presenting with one of these conditions.
- Trial name
- FIBOX (NCT05235685)
- Testing
- Medical air, Hyperoxia
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Grenoble
Cardiomyopathy, Hypertrophic
Study of Exercise Training in Hypertrophic Cardiomyopathy
The investigators propose a pilot randomized controlled trial to determine the safety and potential benefits of moderate intensity exercise in patients with hypertrophic cardiomyopathy.
- Trial name
- RESET-HCM (NCT01127061)
- Testing
- Exercise training
- Where
- 2 sites in United States
- Volunteers
- 136 people
- Sponsor
- University of Michigan
Multiple Myeloma
Study of Hyperbaric Oxygen Therapy in Addition to Standard Growth Factor Support for Hematopoietic Progenitor/Stem Cell Mobilization
The purpose of this study is to evaluate the safety and efficacy of hyperbaric oxygen therapy (HBOT) as a therapeutic option in mobilizing stem cells for autologous stem cell transplant.
- Trial name
- NCT01449539
- Testing
- Hyperbaric Oxygen Therapy
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Arkansas
Obstructive Sleep Apnea, Diabetes Mellitus, Type 2
Correlation Between Nocturnal Oxygen Desaturation and Glycemic Control in Diabetic Patients With Obstructive Sleep Apnea
Nocturnal reduction in blood oxygen is expected independently associated with the development of worsened glycemic control in individuals with type 2 diabetes mellitus.
- Trial name
- NCT04711083
- Testing
- overnight pulse oximetry
- Where
- Egypt
- Volunteers
- 107 people
- Sponsor
- Ain Shams University
Pulmonary Disease, Chronic Obstructive
Ipratropium or Salbutamol Sulphate Alone or Combination Therapy Salbutamol and Ipratropium in Patients With COPD
Study to compare the effects of nebulised salbutamol or ipratropium alone in patients with COPD with those of combined salbutamol and ipratropium nebuliser solution on arterial oxygen saturation (SaO2) and to characterise…
- Trial name
- NCT02182856
- Testing
- Ipratropium bromide 500 µg/salbutamol sulphate 3 mg, Ipratropium 500 µg, Salbutamol sulphate 3 mg
- Volunteers
- 33 people
- Sponsor
- Boehringer Ingelheim
Acute Kidney Injury, End Stage Chronic Renal Failure
Feasibility of Intradialytic Monitoring During CKRT
This is a pilot observational cohort study to understand whether advanced monitoring techniques can be applied during continuous kidney replacement therapy (CKRT), which is the most common form of dialytic therapy provided in…
- Conditions
- Acute Kidney Injury, End Stage Chronic Renal Failure, Dialysis
- Trial name
- NCT07428395
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Pennsylvania
Pulmonary Vascular Disease, Chronic Thromboembolic Pulmonary Hypertension (CTEPH)
Exercise Performance on Ambient Air vs. Low-Flow Liquid Oxygen Therapy in Pulmonary Vascular Disease (PVD)
The investigators aim to study the effect of liquid oxygen therapy (4l/min, nasal) )in Swiss residents with pulmonary vascular diseases (PVD) defined as pulmonary arterial hypertension (PAH) or chronic thromboembolic pulmonary…
- Conditions
- Pulmonary Vascular Disease, Chronic Thromboembolic Pulmonary Hypertension (CTEPH), Pulmonary Arterial Hypertension (PAH)
- Trial name
- NCT07777445
- Testing
- 6-minute walk distance (6MWD) test on ambient conditions, 6-minute walk distance (6MWD) test with supplemental oxygen (LOX)
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Silvia Ulrich Somaini
Cystic Fibrosis
Non-invasive Ventilation and Oxygen Therapy in Cystic Fibrosis Patients With Nocturnal Oxygen Desaturation
The purpose of this study is to determine whether correction of low nighttime oxygen (O2) levels and/ or high carbon dioxide levels in patients with cystic fibrosis improves their quality of life.
- Trial name
- NCT00157183
- Testing
- Nocturnal oxygen , nocturnal bi-level positive pressure ventilation
- Where
- Australia
- Volunteers
- 59 people
- Sponsor
- Bayside Health
Blood Oxygen Desaturations, Sleep-Disordered Breathing
Assessment of the Accuracy of the Non-invasive Wireless Armband Gabi Baby Band for Continuous Vital Parameters Monitoring in Infants and Young Children
During a polysomnography test (PSG) previously prescribed by a physician, the patient also wears the Gaby Baby Band (GBB) during an entire night of sleep.
- Trial name
- WAGSC1 (NCT04886583)
- Testing
- Gabi Baby Band
- Where
- 3 sites in Belgium
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Gabi SmartCare
Status Asthmaticus
High Flow Nasal Cannula in Children With Status Asthmaticus
In France, over 2.5 million people suffer from asthma, including one-third of children. This is the chronic respiratory disease leading to the highest rate of hospitalization.
- Trial name
- CANULASTHM (NCT03157102)
- Testing
- HFNC, Standard Oxygen Treatment
- Where
- 14 sites in France
- Volunteers
- 272 people
- Sponsor
- Hospices Civils de Lyon
COVID-19
Effects of Inspiratory Muscle Training in Patients With Post COVID-19
Coronavirus-2019 (COVID-19) is a new virus that emerged in December 2019 and spread quickly all over the world. Problems such as hypoxia, dyspnea, increased fatigue, decreased exercise capacity and respiratory muscle strength…
- Trial name
- NCT05231395
- Testing
- Inspiratory Muscle Training Group, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Gazi University
Neonatal Respiratory Distress, Very Low Birth Weight Infant
Evaluation of the Impact of SpO2 Averaging Time on Performance of an Automatic FiO2 Control System: a Randomized Study
The aim of the study is to determine the preferred oximeter averaging setting during automated control of FiO2 (A-FiO2) in infants receiving respiratory support and supplemental oxygen.
- Trial name
- NCT05274386
- Testing
- Fabian ventilator with PRICO system (Acutronic Medical Systems AG, Hirzel, Switzerland); SpO2 averaging time set to 4to6 s, Fabian ventilator with PRICO system (Acutronic Medical Systems AG, Hirzel, Switzerland); SpO2 averaging time set to 10 s, Fabian ventilator with PRICO system (Acutronic Medical Systems AG, Hirzel, Switzerland); SpO2 averaging time set to 16 s
- Where
- Czechia
- Volunteers
- 10 people
- Sponsor
- Czech Technical University in Prague
Nursing Care
Effect of Diluted Thyme Honey On Dry Mouth In Intensive Care Unit Patients Exposed to Oxygen Flow Therapy
This research is a randomized, controlled, double-blind, experimental study conducted to investigate the effect of diluted thyme honey on dry mouth in individuals receiving treatment in intensive care and receiving nasal oxygen…
- Trial name
- NCT07358494
- Testing
- diluted thyme honey arm, Mouth wash
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Esra Yaprak Gokturk
Peri-Implantitis and Peri-implant Mucositis
The Use of Adjunct Oxygen High-Level Laser Therapy on the Clinical and Microbiological Outcomes of Peri-implant Disease
The goal of this clinical trial is to learn whether using a special light-activated treatment called photodynamic therapy, or more specifically, its modified version called oxygen high-level laser therapy, using a high-powered…
- Trial name
- NCT07287956
- Testing
- Oxygen high-level laser therapy (Diode laser and hydrogen peroxide), Diode laser therapy
- Where
- Jordan
- Volunteers
- 16 people
- Sponsor
- King Abdullah University Hospital
Acute Stroke
Effects of Repetitive Hyperbaric Oxygen Therapy in Patients With Acute Ischaemic Stroke
Background and Rationale: Cerebrovascular disease is always ranked at the top causes of death and most of hospitalized acute stroke patients have ischemic stroke [1].
- Trial name
- NCT03431402
- Testing
- Hyperbaric oxygen
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kasr El Aini Hospital
Obese
HFNO Versus Nasal CPAP in Obese Patients Undergoing Deep Sedation for ERCP
Endoscopic retrograde cholangio-pancreatography (ERCP) is commonly performed under deep sedation to provide amnesia, comfort, and optimal procedural conditions.
- Trial name
- NCT04912102
- Testing
- high flow nasal oxygen device (HFNO)
- Volunteers
- 270 people
- Sponsor
- Assiut University
Bone Marrow Transplantation, Hematopoietic Stem Cells
Hyperbaric Oxygen Therapy for Hematopoietic Progenitor Cell Collection in Poor Mobilizers
This is a pilot study to evaluate the efficacy of hyperbaric oxygen therapy (HBO2) for mobilizing hematopoietic progenitor cells from bone marrow to blood.
- Conditions
- Bone Marrow Transplantation, Hematopoietic Stem Cells, Multiple Myeloma, Lymphoma
- Trial name
- NCT02682953
- Testing
- Neupogen, Hyperbaric oxygen therapy, Plerixafor
- Where
- United States
- Sponsor
- University of Maryland, Baltimore
Congenital Heart Defect
Prospective Evaluation of Changes in Tissue Oxygen Saturation in Brain and Kidney in Children Admitted to Intensive Care in the Postoperative Period of Cardiac Surgery
It is estimated that the incidence of congenital heart disease varies between 0.5 and 1% of live births, 5,000 new cases per year currently in France These are serious diseases that can be life-threatening to more or less short…
- Trial name
- NCT02884973
- Volunteers
- 30 people
- Sponsor
- University Hospital, Strasbourg, France
Epilepsy
Aromatherapy and Music on Sleep and Children With Epilepsy
Purpose: This study aimed to compare the effects of aromatherapy and music listening with routine care on sleep parameters and cerebral oxygenation in children with epilepsy.
- Trial name
- NCT07827729
- Testing
- Aromatherapy, Music Listening
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Kafkas University
Interstitial Lung Disease
Effects of Upper Extremity Aerobic Exercise Training in Patients With Interstitial Lung Disease
Severe dyspnea, cough, fatigue, restrictive type ventilation disorder, decreased pulmonary function, impaired gas exchange, decreased cardiovascular function and exercise intolerance are frequently encountered findings in…
- Trial name
- NCT05916404
- Testing
- Upper extremity high-intensity interval aerobic exercise training, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Gazi University
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