Clinical trials: Oxygen Metabolism
Energy Expenditure, Body Composition
The Energy Cost of 1-Hour Football Training
This study aims at investigating the energy expenditure following a single Football trainning session in middle aged males. The participants will perform a soccer training session [A single training session including 60 minutes…
- Conditions
- Energy Expenditure, Body Composition, Resting Metabolic Rate, Overweight and Obesity
- Trial name
- FAM (NCT06477705)
- Testing
- FAM
- Where
- Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Type 1 Diabetes
Reactive Oxygen Species in the Pathogenesis of Diabetic Complications
Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic retinopathy and incipient nephropathy in these models.
- Trial name
- NCT00703989
- Testing
- benfotiamine, α-lipoic acid
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Obesity &Amp;Amp; Overweight, Elderly (People Aged 65 or More)
Evaluation of Oxygen Reserve Index (ORi) in Obese and Non-Obese Patients Over 65 Years Old
After obtaining ethical committee approval, this single-center, prospective, observational study included volunteer patients of both sexes, aged 65 years and older, with ASA II-III risk scores, who were scheduled for elective…
- Conditions
- Obesity &Amp;Amp; Overweight, Elderly (People Aged 65 or More), Oxygen Reserve Index
- Trial name
- NCT07679724
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Power, Metabolic Disturbance
Effect of 8-week Intake of 2S-hesperidin on Performance, Body Composition and Biochemicals Markers in Amateur Cyclists
This clinical study evaluates the effect of 500 mg of 2S-hesperidin for 8 weeks on performance (power generated in different metabolic zones), body composition (fat and muscle mass) and biochemical (antioxidant, inflammatory…
- Conditions
- Power, Metabolic Disturbance, Change, Body Weight, Changes Fatty
- Trial name
- HESPERFORMAN (NCT04597983)
- Testing
- 2S-hesperidin
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Francisco Javier Martínez Noguera
Physiological Responses, Pilates Exercise
Effect of Muscle Strengthening Training with Pilates Reformer on Overweight/obese and Normal Body Weight Women (PRET)
This study investigates the physiological responses and the metabolic burden of a Pilates Reformer strength training session in physically inactive premenopausal women with a body mass index of 18-24.9 and 25.01-39.9.
- Conditions
- Physiological Responses, Pilates Exercise, Overweight and Obese Women, Energy Expenditure
- Trial name
- PRET (NCT06675162)
- Testing
- Pilates Reformer Training
- Where
- 2 sites in Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Overweight, Physical Inactivity
The Potential of a Low Oxygen Environmental Chamber as an Aid to Exercise Training to Improve Metabolic Health
Obesity is a major global health issue and a primary risk factor for metabolic-related disorders. While physical inactivity is one of the main contributors to obesity, it is a modifiable risk factor with exercise training as an…
- Conditions
- Overweight, Physical Inactivity, Healthy
- Trial name
- NCT05577429
- Testing
- Low-moderate intensity exercise under normoxia, Low-moderate intensity exercise under moderate hypoxia, Low-moderate intensity exercise under high hypoxia
- Where
- Malaysia
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Swinburne University of Technology
Obesity
Low Oxygen Exposure and Weight Status
The objective of the proposed double-blind, parallel-arm, randomized clinical trial is to evaluate changes in body weight and composition, assess determinants of energy balance (intake and expenditure), and measure modulators of…
- Trial name
- LOWS (NCT05289310)
- Testing
- Normobaric hypoxia (NH), Normobaric normoxia (NN)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Overweight and Obesity, Insulin Sensitivity
Does Hyperbaric Oxygen Therapy Lead to a Sustained Increase in Insulin Sensitivity?
In a recent series of studies performed by our group, we have shown that exposure to hyperbaric oxygen (HBOT) leads to an increase in insulin sensitivity in male subjects and that this improvement can be measured in all men, not…
- Trial name
- HOTAIR3 (NCT02136615)
- Where
- Australia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Adelaide
Body Composition, Physical Fitness
Metabolic Cost of Medicine Ball Training
In this study, the investigators will be able to estimate the metabolic cost of several foundational medicine ball training exercises.
- Conditions
- Body Composition, Physical Fitness, Energy Expenditure, Resting Metabolic Rate
- Trial name
- MΒT-UTH (NCT05412511)
- Testing
- MB-TB, MB-NTB
- Where
- Greece
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Brain Death
Optical Assessment on Brain Death Via a Oxygen Supply Procedure
This study aims to evaluate brain death with optical probes. The changes of hemodynamic parameters including oxyhemoglobin (HbO2) and deoxyhemoglobin (Hb) were detected by near infrared spectroscopy probes attached on the…
- Trial name
- NCT03864887
- Testing
- Oxygen supply of high-low-high procedure, Oxygen supply of low-high-low procedure, Optical monitor for hemodynamic parameter.
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Medical Sciences
Performance Enhancing Product Use, Change, Body Weight
Effects of Acute Glycerol Ingestion on Performance, Metabolic and Biochemical Markers in International Athletes
This clinical study evaluates the acute effect of glycerol ingestion on performance (power output), weight, urine specific gravity, biochemical (antioxidants and lactate) and metabolic (indirect calorimetry) markers in…
- Conditions
- Performance Enhancing Product Use, Change, Body Weight, Change, Body Temperature, Antioxidative Stress
- Trial name
- NCT05295836
- Testing
- GLYCEROL
- Where
- Spain
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Francisco Javier Martínez Noguera
Elite Cyclists, Elite Soccer Players
Exploring the Relationship Between the Gut Microbiome, Physical Fitness Levels and Metabolic Responses to Exercise
Gut microbiota are all microorganisms including bacteria and microscopic eukaryotes that live in the digestive tracts of humans or mammals.
- Conditions
- Elite Cyclists, Elite Soccer Players, Sedentary Behavior
- Trial name
- EXOMIC (NCT05220657)
- Testing
- Maximal incremental exercise test, Submaximal exercise test
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Rennes 2
Healthy Volunteers
Effect of Concurrent and Aerobic Exercise on VO2max, Strength, and Body Composition in Overweight and Obese Adults
Concurrent and aerobic physical exercise are recognized strategies for the treatment of overweight and obesity. The interventions of these modalities have been performed with cardiovascular machines or guided execution in their…
- Trial name
- NCT05867498
- Testing
- Concurrent exercise, Aerobic exercise
- Where
- Colombia
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Universidad de Antioquia
Hyperoxia / High FiO₂ Exposure, Interval Training
Oxygen as a Metabolic Modulator: Divergent Physiological Adaptations to Hypoxic and Hyperoxic Tabata Training.
The purpose of this study is to examine how breathing air with different oxygen concentrations (higher or lower than normal) during high-intensity interval training affects: Aerobic capacity (VO₂max) Ventilatory thresholds Blood…
- Conditions
- Hyperoxia / High FiO₂ Exposure, Interval Training, HIIT, High Intensity Interval Training
- Trial name
- NCT07551869
- Testing
- FIO2 modulation during HIIT protocol on assault bike
- Where
- Belgium
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Haute Ecole Bruxelles-Brabant
Open Angle Glaucoma, Normal Tension Glaucoma
Study on the Oxygen Saturation in Pulsating and Non-pulsating Central Retinal Veins
Retinal ischemia is thought to play an important role in the pathogenesis of glaucoma. Recent findings have confirmed that there is a direct correlation between the levels of venous oxygen saturation and the degree of the…
- Trial name
- NCT01794442
- Where
- Belgium
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Neurodegenerative Diseases
Cerebrovascular Reactivity and Oxygen Metabolism as Markers of Neurodegeneration After Traumatic Brain Injury
This grant award entitled, "Cerebrovascular Reactivity and Oxygen Metabolism as Markers for Neurodegeneration after Traumatic Brain Injury" (hereafter, "Neurovascular Study"), aims to determine if neurovascular contributors to…
- Trial name
- NCT04820881
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Washington D.C. Veterans Affairs Medical Center
Healthy Subjects
Interval Training and Resting Metabolism
It has been reported that obese individuals are seated 2 ½ hour more than lean individuals and that non exercise thermo genesis (NEAT) may vary with as much as 2000 Kcal/day between equal size people due to different occupational…
- Trial name
- NEAT (NCT01313468)
- Testing
- 1 x 4 minute interval, 4 x 4 minutes Intervals, Moderate continuous Training
- Where
- Norway
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Type 1 Diabetes
Muscle Oxygenation, Type 1 Diabetes, and Glycated Hemoglobin
Most of the studies concerning aerobic fitness in Type 1 diabetic patients noted a relationship between impaired aerobic fitness and high glycated haemoglobin (HbA1c) levels, reflecting poor long term glycaemic control.
- Trial name
- OXYDIAB (NCT02051504)
- Testing
- Incremental maximal exercise, Oral Glucose Tolerance Test, Muscle biopsy
- Where
- France
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Kidney Function Tests
AGE - Functional Reserve
Renal functional reserve is defined as the glomerular hyper filtration induced by a protein load. Renal blood flow and Glomerular Filtration Rate (GFR) increase in response to a protein load.
- Trial name
- AGE-FR (NCT02695251)
- Testing
- low AGE meal, High AGE meal
- Where
- France
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Type 1 Diabetes Mellitus
Cardiopulmonary Fitness, Lung Function, Muscular Oxygen Saturation, and Quality of Life in T1DM
The purpose of this study is to compare the differences of 1. cardiopulmonary fitness 2. lung function 3. muscular oxygen saturation 4. quality of life between type 1 diabetes mellitus and healthy adults.
- Trial name
- NCT01727661
- Testing
- exercise testing with near-infrared spectroscopy, lung function testing, quality of life
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital