Clinical trials: Ozone, open to volunteers
Carpal Tunnel, Dexmedetomidine
Dexmedetomidine, Ozone and Dexamethasone Local Injection in Carpal Tunnel Syndrome for Pain Relief
The aim of the present study is to compare the analgesic efficacy of Dexmedetomidine, Ozone and Dexamethasone regional injection in carpal tunnel syndrome.
- Conditions
- Carpal Tunnel, Dexmedetomidine, Ozone, Dexamethasone
- Trial name
- NCT06133712
- Testing
- Dexmedetomidine, Ozone, Dexamethasone
- Where
- Egypt
- Volunteers
- 135 people
- Sponsor
- Tanta University
Chemotherapy-induced Peripheral Neuropathy, Pain, Neuropathic
Ozone Therapy in Chemotherapy-induced Peripheral Neuropathy: RCT (O3NPIQ)
The main objective of this clinical trial is to evaluate the effectiveness and cost-effectiveness of adding ozone therapy to the clinical management of patients with pain secondary to chemotherapy-induced peripheral neuropathy
- Conditions
- Chemotherapy-induced Peripheral Neuropathy, Pain, Neuropathic, Pain Syndrome
- Trial name
- O3NPIQ (NCT04299893)
- Testing
- Ozone, Oxygen
- Where
- 2 sites in Spain
- Volunteers
- 42 people
- Sponsor
- Bernardino Clavo, MD, PhD
Fibromyalgia
Impact of Major Ozone Autohemotherapy on Sarcopenia Parameters in Fibromyalgia
Fibromyalgia syndrome (FMS) is a chronic and heterogeneous disorder characterized primarily by widespread pain, accompanied by sleep disturbances, fatigue, depressive symptoms, and cognitive dysfunction.
- Trial name
- NCT07680621
- Testing
- Major Ozone Autohemotherapy, Exercise Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sakarya University
Interstitial Cystitis, Bladder Pain Syndrome
Intravesical Ozone Therapy for Interstitial Cystitis/Bladder Pain Syndrome
This randomized, double-blind, placebo-controlled trial evaluated the efficacy and safety of intravesical ozone therapy in 60 patients with interstitial cystitis (IC).
- Trial name
- NCT06863220
- Testing
- Intravesical Ozone Therapy, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Knee Osteoarthritis
Dose-Response Effect of Intra-Articular Ozone in Knee Osteoarthritis
The goal of this clinical trial is to evaluate the clinical efficacy of different doses of intra-articular ozone injections combined with exercise in patients aged 40-75 diagnosed with Grade 2-3 knee osteoarthritis.
- Trial name
- NCT07678996
- Testing
- ozone injection, Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Kayseri City Hospital
Ozone Gel, Chlorohexidine Gel
Ozone Gel Versus Chlorohexidine Gel as an Adjunct to Non-Surgical Treatment of Stage II Periodontitis Grade B Among Smokers Patients
The aim of the present study is to evaluate and compare the clinical and biochemical outcomes of Ozoral® and High Cure® (chlorhexidine gel) as adjuncts to non-surgical periodontal therapy in smoker patients with Stage II Grade B…
- Conditions
- Ozone Gel, Chlorohexidine Gel, Non-Surgical Treatment, Stage II Periodontitis
- Trial name
- NCT07923708
- Testing
- Conventional scaling and root planing, Conventional scaling and root planing in addition to chlorhexidine gel, Conventional scaling and root planing in addition to ozone gel
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- October 6 University
Erectile Dysfunction Following Radical Prostatectomy
Intracavernosal Exosomes vs. Rectal Ozone for Post-RARP Erectile Dysfunction
This prospective, randomized, controlled trial aims to evaluate and compare the therapeutic efficacy of intracavernosal urine-derived exosomes and systemic rectal ozone therapy in patients experiencing erectile dysfunction (ED)…
- Trial name
- REHAB-RARP (NCT07707505)
- Testing
- Urine-Derived Exosomes (USC-Exos), Rectal Medical Ozone Insufflation, Daily Phosphodiesterase type 5 (PDE5) Inhibitor
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Oral Mucositis, Chemotherapy-induced Oral Mucositis
Ozone Therapy With Biomimetic Oral Care for Cancer-Related Oral Mucositis
Oral mucositis is a frequent and often debilitating complication of radiotherapy and chemotherapy, particularly in patients treated for head and neck cancers.
- Conditions
- Oral Mucositis, Chemotherapy-induced Oral Mucositis, Head and Neck Neoplasms
- Trial name
- OZOMUC (NCT07491536)
- Testing
- Gas Ozone Therapy, Biomimetic Oral Care Regimen
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University of Pavia
Carpal Tunnel Syndrome (CTS), Glucocorticoid
Glucocorticoid, Ozone and 5% Dextrose Local Injection for Pain Relief in Carpal Tunnel Syndrome
This study aims to compare the efficacy and outcomes of perineural injection with 5% dextrose, local ozone and glucocorticoid injection in the management of carpal tunnel syndrome.
- Conditions
- Carpal Tunnel Syndrome (CTS), Glucocorticoid, Pain, Dextrose
- Trial name
- NCT07498998
- Testing
- Perineural injection with 5% dextrose (D5W)., Local ozone injection, Local glucocorticoid injection (dexamethasone).
- Where
- Egypt
- Volunteers
- 105 people
- Sponsor
- Tanta University
Chemotherapy Induced Peripheral Neuropathy (CIPN), Paresthesia
Gut Microbiome Profiles in Patients With Chemotherapy-induced Neuropathy in the RCT OzoParQT (NCT06706544).
Chemotherapy-induced peripheral neuropathy (CIPN) is a common and debilitating side effect of chemotherapy (CT), often requiring dose reductions or treatment interruptions, which can compromise efficacy of the planned CT…
- Conditions
- Chemotherapy Induced Peripheral Neuropathy (CIPN), Paresthesia, Numbness, Tingling
- Trial name
- OzoParQTmicrob (NCT06799351)
- Testing
- Ozone therapy
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- Bernardino Clavo, MD, PhD
Chemotherapy-Induced Peripheral Neuropathy, Radiation Toxicity
Patients Referred to the Chronic Pain Unit for Palliative Treatment With Ozone Therapy Between 2026 and 2029.
The main objective of this study is to analyze the impact on the health-related quality of life of patients with refractory symptoms who have been referred to the Dr.
- Conditions
- Chemotherapy-Induced Peripheral Neuropathy, Radiation Toxicity, Chronic Pain, Delayed Wound Healing
- Trial name
- EPOOzo-2 (NCT07325851)
- Testing
- Ozone Therapy
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Bernardino Clavo, MD, PhD