Clinical trials: Ozone
Dental Caries
Healozone Study to Evaluate the Safety and Efficacy of the Use of Ozone for Management of Dental Caries
Caries means demineralization with the formation of cavities and pulp symptoms and necrosis as an end result. The acids in the mouth are mainly produced by oral bacteria like Streptococcus mutans from bacterial biofilms adhering…
- Trial name
- NCT00495495
- Testing
- Ozone treatment
- Where
- 3 sites in United States
- Volunteers
- 394 people, healthy volunteers welcome
- Sponsor
- Indiana University
Asthma and/or Exercise Induced Bronchoconstriction, Ozone Air Pollution
Salbutamol Use in Ozone Air Pollution by People With Asthma and/or Exercise Induced Bronchoconstriction (EIB)
Salbutamol use is increased in areas with high levels of ozone pollution and the potential consequences of this are not well known.
- Trial name
- NCT05087693
- Testing
- Salbutamol, Ozone, Filtered Air
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- University of British Columbia
Ozone Exposure During Rest and Exercise
Susceptibility of Cardiorespiratory Responses to Ozone During Cycling Exercise
Ground level ozone (O3) is a common airborne pollutant that is well recognized to cause negative respiratory symptoms and impair pulmonary function.
- Trial name
- NCT05473000
- Testing
- Exercise, Ozone, Room air
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Trochanteric Bursitis
Comparison of Ozone and Steroid Injection in Patients With Greater Trochanteric Pain Syndrome
Between the large trochanter and the muscles adhering to it, trochanteric bursa and several other bursa may be found. Trochanteric bursitis can be alone or together with tendinitis of other bursa and adhering muscles.
- Trial name
- NCT04420572
- Testing
- ozone injection, betamethasone
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Air Pollution
Air Pollution Study: The Effect of Ozone on the Lung
The purpose of the study is to better understand the mechanisms of lung injury from ozone exposure. Subjects will participate in two exposure sessions: filtered air and 0.2 ppm ozone.
- Trial name
- NCT02673775
- Testing
- Clean Air, Ozone
- Where
- United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Environmental Exposure, Nasal Inflammation
Human Biological Responses to Low Level Ozone
To investigate if low level ozone exposure will cause measurable inflammation in nasal cells.
- Trial name
- SNOZ (NCT02857283)
- Testing
- Ozone, Filtered Air, Health and Exposure Tracker (HET)
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
MEDICATION RELATED OSTEONECROSIS OF THE JAW
OZONE_EXO: Comparative Analysis of Protocols for Dental Exactions in Patients at Risk of MRONJ: Case-control Study
Medication-related osteonecrosis of the jaw (MRONJ) is a serious adverse reaction of antiresorptive and antiangiogenic agents; it is also a potentially painful and debilitating condition.
- Trial name
- OZONE_EXO (NCT06072404)
- Testing
- OxigenOzone_Insufflation
- Where
- Italy
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- University of Palermo
Healthy
Mechanisms of Ozone-Induced Alterations in Efferocytosis and Phagocytosis
The purpose of this research study to understand how environmental and genetic factors may be involved in lung function. Healthy Study participants will undergo a 1-day screening that includes a blood draw and breathing testing…
- Trial name
- MOZEPH (NCT03646877)
- Testing
- Ozone, Filtered Air
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Robert Tighe, MD
Mild Asthma
Genetic Susceptibility to Ozone in Mild Asthmatic Volunteers
Recent reports have shown that people with asthma who have a particular gene, known as the GSTM1 null gene, are more susceptible to the effect of air pollutants.
- Trial name
- Glutoz (NCT00287365)
- Testing
- ozone
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of North Carolina, Chapel Hill
Environmental and Genetic Factors on Lung Function
ONES Grant: CXCL10/CXCR3 Regulation of Ozone-Induced Epithelial Permeability
The purpose of this research study to understand how environmental and genetic factors may be involved in lung function. Study participants will undergo a 1-day screening that includes a blood draw and breathing testing, return…
- Trial name
- NCT03599206
- Testing
- Ozone, Filtered Air
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Robert Tighe, MD