Clinical trials: PAD - Peripheral Arterial Disease
Peripheral Arterial Disease
Artificial Intelligence for Early Detection of Peripheral Artery Disease
The goal of this clinical trial is to test an AI-based screening tool that will help to identify patients at high risk of having undiagnosed peripheral artery disease.
- Trial name
- (AID-PAD) (NCT06505317)
- Testing
- AI-based PAD screening intervention
- Volunteers
- 7,800 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Peripheral Artery Disease, Popliteal Aneurysm
Observational GORE® VIABAHN® Endoprosthesis With PROPATEN Bioactive Surface Global Registry
Collect real-world post-market clinical follow-up data on patients treated with the GORE® VIABAHN® Endoprosthesis with PROPATEN Bioactive Surface (VSX)
- Conditions
- Peripheral Artery Disease, Popliteal Aneurysm, Hemodialysis Access, Visceral Artery Aneurysms
- Trial name
- NCT04907240
- Testing
- GORE® VIABAHN® Endoprosthesis with PROPATEN Bioactive Surface (VSX)
- Where
- 26 sites in Belgium, France and 7 more
- Volunteers
- 614 people
- Sponsor
- W.L.Gore & Associates
Peripheral Arterial Disease, Vascular Diseases, Peripheral
The Role of microRNA-210 in Regulating Oxidative Stress in Patients With PAD
MicroRNA-210 (miR-210) can be a potential therapeutic target of patients with peripheral artery disease (PAD). Recent evidence suggests the role of miR-210 and oxidative stress in the pathophysiology of PAD and its association…
- Conditions
- Peripheral Arterial Disease, Vascular Diseases, Peripheral, Arterial Occlusive Diseases, Atherosclerosis
- Trial name
- NCT04089943
- Testing
- Revascularization operation, Control group
- Where
- 2 sites in United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University of West Florida
Critical Limb Ischemia
Acceleration Time Assessment for Prediction of Critical Limb Ischemia
Critical Limb Ischaemia (CLI), the final stage of arterial disease, is a therapeutic emergency whose prognosis depends largely on the time taken to diagnose it.
- Trial name
- ATACLI (NCT06296576)
- Testing
- arterial ultrasound scan
- Where
- 3 sites in France
- Volunteers
- 431 people
- Sponsor
- Centre Hospitalier le Mans
Peripheral Arterial Disease
Prospective, Multi-center, Single-arm Study of the Auryon Laser System for Treatment of Below-the-Knee (BTK) Arteries
The Auryon Laser Atherectomy System has been cleared by the FDA to treat infrainguinal arterial disease including in-stent restenosis
- Trial name
- NCT05284240
- Testing
- Auryon Laser System
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Midwest Cardiovascular Research Foundation
Peripheral Arterial Disease
Real-World Safety Analysis of Paclitaxel Devices Used for the Treatment of Peripheral Arterial Disease
Treatment with paclitaxel-based endovascular devices (PED) has become a common treatment option for patients with peripheral artery disease (PAD) involving the femoral-popliteal artery.
- Trial name
- NCT04647643
- Testing
- Paclitaxel
- Where
- United States
- Volunteers
- 8,000 people
- Sponsor
- Lahey Clinic
Peripheral Arterial Disease
Ultrasound Perfusion Estimation for Assessment of Peripheral Arterial Disease
The purpose of this study is to develop a new noninvasive tool for early diagnosis of Peripheral Arterial Disease (PAD) and use the proposed method for monitoring the disease progression and the response to interventional…
- Trial name
- NCT06952543
- Testing
- Ultrasound Imaging
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Peripheral Arterial Disease
Doppler Flow Classification of Saint-Bonnet
Observational Study that evaluates the interest of Doppler waveforms classification in Peripheral Artery disease
- Trial name
- Saint-Bonnet (NCT03464617)
- Where
- 10 sites in France
- Volunteers
- 1,000 people
- Sponsor
- Rennes University Hospital
Critical Limb Ischemia
PROMISE International
The objective of this post-market study is to evaluate the safety and effectiveness of the LimFlow System in creating a below-the-knee arterio-venous fistula for venous arterialization in subjects with critical limb ischemia.
- Trial name
- NCT03321552
- Testing
- Percutaneous deep vein arterialization, LimFlow System
- Where
- 12 sites in Austria, Germany and 3 more
- Volunteers
- 34 people
- Sponsor
- LimFlow SA
Peripheral Arterial Disease
Smartstep Smartphone PAD
The study aim is to evaluate the effectiveness of a coached, smartphone-enabled exercise program versus physician directed exercise therapy (usual care).
- Trial name
- SMARTSTEP (NCT03479255)
- Testing
- Smartphone-enabled structured exercise therapy (SE-SET), Standard exercise therapy
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Emory University
Peripheral Arterial Disease, Peripheral Vascular Disease
A Study to Collect Intravascular Ultrasound Images Before and After Treatment With the Jetstream System
The Jetstream System is a commercially available rotating, aspirating, expandable catheter designed to remove atherosclerotic plaque and blood clots in the lower limbs.
- Trial name
- NCT00911417
- Testing
- Pathway Jetstream Atherectomy System
- Where
- 5 sites in United States
- Volunteers
- 40 people
- Sponsor
- Pathway Medical Technologies Inc.
Peripheral Arterial Disease
To Verify the Efficacy and Safety of Rapamycin Coated Peripheral Balloon Catheter in the Treatment of Femoral Popliteal Artery Disease
A prospective randomized trial to validate the efficacy and safety of rapamycin coated peripheral balloon catheter in the treatment of femoral popliteal artery disease.
- Trial name
- NCT05662618
- Testing
- Percutaneous selective arteriography of peripheral arteries
- Where
- China
- Volunteers
- 276 people
- Sponsor
- Shanghai Bomaian Medical Technology Co., Ltd
Peripheral Arterial Disease
Text Messaging to Promote Walking Among Latino Adults at Risk for Peripheral Arterial Disease
The purpose of this study is to learn about the impact of text messaging on physical activity in persons with risk factors for peripheral arterial disease (PAD).
- Trial name
- NCT02622282
- Testing
- Text Messages, Phone Calls, Handout
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Myocardial Infarction, Unstable Angina Pectoris, Sudden Cardiac Death, Stroke, Peripheral Artery Disease
Protective Effect of EPA on Cardiovascular Events
The purpose of this study was to test the hypothesis that the long-term use of highly (>98%) purified EPA, in addition to HMG-CoA reductase inhibitor (statin), would be more effective than statin alone in preventing…
- Trial name
- NCT00231738
- Testing
- Eicosapentaenoic acid ethyl ester(EPADEL Capsule 300 TM)
- Where
- Japan
- Volunteers
- 18,000 people
- Sponsor
- Kobe University
Carotid Artery Diseases, Aortic Diseases
Intervascular Post-Market Clinical Follow-Up (PMCF) Registry
The purpose of this registry is to evaluate the long-term safety and performance of Intervascular Vascular Grafts and Patches (Intergard Standard, Hemashield, Intergard Silver, Intergard Synergy) for bypass, repair or replacement…
- Conditions
- Carotid Artery Diseases, Aortic Diseases, Peripheral Arterial Diseases
- Trial name
- NCT07322913
- Testing
- Intergard Standard - Collagen Coated Vascular Grafts and Patches, Hemashield - Collagen Coated Vascular Grafts and Patches, Intergard Silver - Antimicrobial Collagen Coated Vascular Grafts and Patches
- Where
- 5 sites in United States, Belgium and 2 more
- Volunteers
- 1,200 people
- Sponsor
- Intervascular
Peripheral Arterial Disease, Intermittent Claudication
Treatment of SFA Lesions With 480 Biomedical STANZA™ Drug-Eluting Resorbable Scaffold (DRS) System
An evaluation of the safety and performance of the STANZA Drug-eluting Resorbable Scaffold (DRS) system for the treatment of patients with obstructive superficial femoral artery disease.
- Conditions
- Peripheral Arterial Disease, Intermittent Claudication, Vascular Diseases, Cardiovascular Diseases
- Trial name
- SPRINT (NCT02097082)
- Testing
- STANZA Drug-eluting resorbable Scaffold
- Where
- 9 sites in Austria, Germany and 2 more
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- 480 Biomedical
Atherosclerosis
A Proof of Concept Study to Determine the Local Delivery and Efficacy of Nanocort
A promising strategy to reduce CVD is to directly target inflammation at the level of the vessel wall. A potential drawback of anti-inflammatory strategies pertains to the thin line between inhibiting 'inappropriate' inflammation…
- Trial name
- DELIVER (NCT01647685)
- Testing
- Nanocort, Methylprednisolone
- Where
- Netherlands
- Volunteers
- 21 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Peripheral Arterial Disease (PAD)
Randomized Trial of IN.PACT Admiral® Drug Coated Balloon vs Standard PTA for the Treatment of SFA and Proximal Popliteal Arterial Disease
The objective of this Study is to evaluate the safety and efficacy of the IN.PACT Admiral® drug coated PTA balloon, utilized for the dilatation of the narrowed sections of the artery, as compared to other standard (non drug…
- Trial name
- INPACT SFA I (NCT01175850)
- Testing
- Drug-Coated Balloon (DCB), PTA Balloon: Balloon Angioplasty
- Where
- Germany
- Volunteers
- 331 people
- Sponsor
- Medtronic Endovascular
Peripheral Artery Disease
Compare I Pilot Study for the Treatment of Subjects With Symptomatic Femoropopliteal Artery Disease
To compare two different Paclitaxel coated balloons in the treatment of high grade stenotic or occluded lesions in Superficial femoropopliteal artery (SFA )and/or Proximal Popliteal Artery in Peripheral Artery Disease (PAD)…
- Trial name
- NCT02701543
- Testing
- Ranger Drug Eluting Balloon, In Pact Drug Eluting Balloon
- Where
- Germany
- Volunteers
- 414 people
- Sponsor
- University of Leipzig
Peripheral Arterial Disease
Pulsed Electromagnetic Field Versus Treadmill Walking in Peripheral Arterial Disease
my study is to determine the effect of pulsed electromagnetic field versus treadmill training in managemet of intemittent claudication in peripheral arterial disease there is a lack of interventions that improves local peripheral…
- Trial name
- NCT04621097
- Testing
- pulsed electromagnetic field, treadmill training, Medication
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Cairo University
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