Clinical trials: PALS
Patient Education
A Pilot Study of the Impact of the Patient Activated Learning System (PALS) on Knowledge Acquisition, Recall, and Decision Making
This is a randomized pilot study comparing the impact of the Patient Activated Learning System (PALS) on knowledge acquisition, recall, and decision making about antihypertensive medication compared to an established online…
- Trial name
- NCT03156634
- Testing
- PALS, WebMD
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
ALS
A Pilot Trial of Triheptanoin for People With Amyotrophic Lateral Sclerosis (PALS)
The causes of ALS are largely unknown. However, mitochondrial dysfunction, resulting in impaired energy production, oxidative stress and apoptosis, may play a key role in ALS progression.
- Trial name
- NCT03506425
- Testing
- Triheptanoin
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Richard Bedlack, M.D., Ph.D.
Pediatric Housestaff
Effect of Simulation on PALS Training
Patient simulation is a new and expanding technology that has proven effective as a teaching tool in various clinical settings, but data on pediatric simulation is lacking.
- Trial name
- NCT00562744
- Testing
- Simulation
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Crisis Resource Management
Can Adherence to PALS Guidelines be Improved by Team Training of Pediatric Resuscitation Members?
A multi-centre prospective cohort study, which examines the effect of a team training educational intervention for pediatric resuscitation team members.
- Trial name
- Teams4Kids (NCT02075645)
- Testing
- Team training course
- Where
- Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Pediatric Advanced Life Support (PALS)
Comparing the Effectiveness of Large Language Model-Based and Video-Based Refresher Education on Knowledge Retention After Simulation-Based Pediatric Cardiopulmonary Resuscitation Training: A Six-Month Follow-Up Study
This study aims to compare the effectiveness of large language model (LLM)-based refresher education and video-based refresher education for maintaining knowledge and performance after simulation-based Pediatric Advanced Life…
- Trial name
- NCT07783932
- Testing
- LLM-Based Refresher Education, Video-Based Refresher Education
- Where
- South Korea
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Iron-deficiency
Effect of Polyphenols on Absorption of Iron From Sodium Iron Chlorophyllin
Polyphenols present in tea are known to inhibit the absorption of non heme iron. The inhibiting effect of tea on non-heme iron absorption is attributed to the flavonoids present in tea.
- Trial name
- polySIC (NCT04849832)
- Testing
- SIC, SIC + tea, FeSO4
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Colon Cancer Prevention
Exploring the Effects of a High Chlorophyll Dietary Intervention to Reduce Colon Cancer Risk in Adults
Colon cancer is the third most common cancer in men and women and over 70% of cases are preventable. A western diet, characterized by low vegetable and high red and processed meat intake, indisputably increases colon cancer risk.
- Trial name
- M3G (NCT03582306)
- Testing
- High chlorophyll diet - intervention 1st, High chlorophyll diet - control 1st
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Auburn University
Diabetes Mellitus
Family PALS (PArtners in Lifestyle Support)
NOTE: This study is in the trial-phase of a 5-year study that included a formative research phase (Phase 1 - IRB study # 07-1765 "Family-based Diabetes Self-management Training for African American Adults").
- Trial name
- PALS (NCT01324011)
- Testing
- Adult diabetes family-based weight loss intervention
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Healthy Male Volunteers
A Study in Healthy Male Participants to Compare How CHF10196 Affects How the Body Absorbs and Processes Two Commonly Used Medicines: Dabigatran, a Blood Thinner, and Rosuvastatin, a Medicine Used to Lower Cholesterol
The purpose of this study is to assess the potential drug-drug interaction of CHF10196 (a dipeptidyl peptidase 1 inhibitor) and its metabolite on the pharmacokinetics of dabigatran (a P-glycoprotein substrate) and Rosuvastatin (a…
- Trial name
- NCT07744386
- Testing
- Dabigatran Etexilate, Rosuvastatin, CHF10196
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Chiesi Farmaceutici S.p.A.
Health Knowledge, Attitudes, Practice
PALS for Pap Smear Follow up
In this study, the researchers will utilize information gained from patient interviews about their knowledge of the cervical cancer screening and treatment process, and perceived barriers surrounding appropriate follow up, to…
- Trial name
- PALS (NCT04070534)
- Testing
- PALS
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Healthy Volunteers
A Study to Compare How CHF10196 (Florensocatib) is Absorbed Into the Blood When Given Alone and With a Drug That Reduces Stomach Acid in Healthy Male Participants
This Phase 1 study evaluates the effect of pantoprazole (a proton pump inhibitor) on the pharmacokinetics (PK) of CHF10196 (Florensocatib) in healthy male participants.
- Trial name
- NCT07683793
- Testing
- CHF10196, Pantoprazole
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Chiesi Farmaceutici S.p.A.
Neuralgia, Perineal
Promoting Optimal Healing After Laceration Repair Study
The goal of this research is to investigate three different methods of perineal skin closure during second-degree perineal wound repair and determine which method is associated with the least amount of patient pain.
- Trial name
- PALS (NCT02055794)
- Testing
- Suturing of the perineal skin, Closing perineal skin with surgical glue, No suturing of the perineal skin
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Papillon-Lefevre Disease
Cytokines in Papillon-Lefèvre Syndrome
Papillon-Lefèvre syndrome (PLS) is characterised by aggressively progressive periodontitis combined with palmo-plantar hyperkeratosis. It is caused by "loss of function" mutations in the cathepsin C gene.
- Trial name
- NCT01116934
- Where
- Germany
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Goethe University
Nutrition Disorders
PALS for Nutrition Education
The overall goal of this inquiry is to determine whether PALS is more effective than comparable online resources at educating patients in the outpatient clinic setting about nutrition.
- Trial name
- NCT04196517
- Testing
- Educational Tool, PALS, WebMD
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Physical Activity, Weight
Physical Activity and Leisure-time Study (PALS)
Physical inactivity is a major public health problem and a primary contributing factor to the obesity epidemic. While most Americans do not meet the physical activity (PA) guidelines (30 min/day, 5 day/wk), they do report…
- Trial name
- PALS (NCT01342471)
- Testing
- TV commercial stepping, 30-min walk
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Communication, Trust
CALS Patient Activated Learning System (PALS)
The overall goal in this line of inquiry is to test whether the Patient Activated Learning System (PALS) is effective in reducing disparities in access to reliable, easily understood health information, and whether this increased…
- Conditions
- Communication, Trust, Health Knowledge, Attitudes, Practice
- Trial name
- NCT04212117
- Testing
- The Patient Activated Learning System (PALS), WebMD
- Where
- United States
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- Cornell University
Iron Deficiency
Evaluation of Iron Bioavailability From Iron Chlorophyllin
The overall objective of this study is to evaluate the iron absorption from iron chlorophyllin. Iron deficiency is a public health problem in both developing and industrialized countries.
- Trial name
- NCT04602247
- Testing
- SIC, SIC + AA combined, FeSO4
- Where
- Switzerland
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Amyotrophic Lateral Sclerosis (ALS)
Examining Interactions Between PALS and Caregivers
The goal of this clinical trial is to learn about the effect of communicative interaction on verbal communication in people with amyotrophic lateral sclerosis (ALS) and their caregivers.
- Trial name
- NCT06819124
- Testing
- Structured Communicative Interaction, Unstructured communicative interaction
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Penn State University