Clinical trials: PCO
PCO
Dapagliflozin Versus Metformin and Their Combination in Polycystic Ovary Syndrome
The aim of this study is to compare the hormonal, metabolic and clinical effects of metformin and dapagliflozin as monotherapies and the effect of both of them as a combined therapy in women with PCOs.
- Trial name
- NCT05601336
- Testing
- Dapagliflozin 5 MG, Metformin Hydrochloride 1000 MG, Dapagliflozin/Metformin
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Beni-Suef University
Induction of Ovulation, PCO - Polycystic Ovaries
Sodium-Glucose Co-Transporter-2 Inhibitors as Adjuvant Therapy With Letrozole in Induction of Ovulation in Women With Polycystic Ovarian Syndrome
The aim of the study is to assess the efficacy of adjuvant therapy dapagliflozin, metformin as monotherapy and combination of both in comparison to control group in induction of ovulation with letrozole in women PCOS, focusing…
- Trial name
- SGLT-2/PCOS (NCT07589075)
- Testing
- Metformin 1000 mg Oral Tablet, Dapagliflozin 10 MG Oral Tablet [Farxiga], Combined Dapagliflozin-Metformin 5/1000mg
- Where
- Egypt
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
IVF, PCO
Progesterone Primed Protocol Versus GnRH Antagonist in With PCO Undergoing ICSI
To compare the effectiveness and safety of Progesterone Primed Ovarian Stimulation protocol (PPOS) using Dydrogestrone vs GnRH Antagonist Protocol in patients with expected high ovarian response undergoing ICSI cycle
- Trial name
- NCT05951400
- Testing
- Dydrogesterone Tablets, Cetrorelix
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Beni-Suef University
PCO - Polycystic Ovaries, Obesity and Obesity-related Medical Conditions
The Effectiveness of Astaxanthin Supplementation on the Clinical Symptoms and Cardio-metabolic Profile in Women with Polycystic Ovary Syndrome
Abstract Background: This trial aims to investigate the effect of 12 weeks of 10 mg/day astaxanthin (ASX) administration compared with the control group on insulin sensitivity, lipid profile, circulating MDA levels, severity of…
- Trial name
- NCT06642363
- Testing
- Subjects in the intervention group will receive one capsule containing 10 mg Astaper day made by the "Zyest Technology Tarawat Zendig" institute in Iran. The dosage of ASX is determined based on the s
- Where
- Iran
- Volunteers
- 44 people
- Sponsor
- Isfahan University of Medical Sciences
PCO
Effect of Metformin and Combination of Olive Oil Plus Nutritional Supplements on Inflammatory Markers IL-6 and IL-8 in PCOS.
The investigators aim is to conduct randomized clinical trial, to determine the effects of metformin and combination of olive oil plus nutritional supplements on inflammatory markers IL-8 and IL6 in polycystic ovarian syndrome…
- Trial name
- NCT05952349
- Testing
- OLIVE OIL 5ML/5MG (BD) NUTRITIONAL SACHET 2100MG (BD), Metformin (1000 mg Twice a day)
- Where
- Pakistan
- Volunteers
- 88 people
- Sponsor
- Khyber Medical University Peshawar
Polycystic Ovary Syndrome, PCO
Effects of HICT and Intermittent Fasting on PCOS
The goal of this randomized controlled trial is to compare the effects of High intensity circuit training, Intermittent Fasting, and their combination on PCOS morphology, Anthropometrics, clinical hyperandrogenism and body image…
- Trial name
- NCT06302166
- Testing
- High Intensity Circuit training (HICT), Intermittent Fasting (IF), Combination of HICT and IF
- Where
- 2 sites in Pakistan
- Volunteers
- 33 people
- Sponsor
- Riphah International University
PCO - Polycystic Ovaries, Infertility
Mild Stimulation Protocol Using Clomiphene Citrate for Women With PCOS Undergoing in Vitro Fertilization
Infertility is of increasing significance affecting almost 48.5 million couples around the world. Anovulation is a major cause of infertility in women with polycystic ovary syndrome (PCOS) accounting for about 80% of women with…
- Trial name
- NCT04157725
- Testing
- mild stimulation protocol: oral Clomiphene Citrate, Conventional Stimulation Protocol: will receive FSH/HMG
- Where
- Lebanon
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Primary Hypothyroidism, Acupuncture
Effect of Acupuncture and Low Caloric Diet on Primary Hypothyroidism and Irregular Menstruation in Infertile Women
the goal of this randomize clinical trial is to compare in 60 infertile women with hypothyroidism. selected from national Nutritional institute out clinic.
- Conditions
- Primary Hypothyroidism, Acupuncture, Irregular Menstruation, PCO
- Trial name
- NCT05804149
- Testing
- acupuncture, Thyroxine, low caloric diet
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
PCO, Induction of Ovulation
Parameters Declaring PCO Infertile Patients Either Sensitive or Resistant to Different Doses of Clomiphene Citrate.
Polycystic ovary syndrome (PCOS) is a common endocrinological disorder seen in 6%-10% of women (Human Reproduction, 2004). It is characterized by polycystic ovaries, anovulatory cycles, and hyperandrogenism.
- Conditions
- PCO, Induction of Ovulation, Clomiphene Citrate
- Trial name
- NCT04887402
- Testing
- Clomiphene Citrate
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
PCO
Added Value of N Acetyle Cysteine to Clomiphene Citrate in PCO
PCO is one of the factors associated with delayed conception
- Trial name
- NCT04170439
- Testing
- Clomiphene plus metformin plus N acetyle cysteine in arm number 1, Clomiphene citrate plus metformin with chromium, clomiphene citrate plus metformin
- Where
- 2 sites in Egypt
- Volunteers
- 108 people
- Sponsor
- Aljazeera Hospital
PCO
Metformin Versus Acarbose Treatment in Infertile Overweight Women With Polycystic Ovary Syndrome (PCOS)
This study is a prospective randomized clinical trial to compare the endocrine and metabolic effects of two anti diabetic drugs (metformin vs. acarbose) in infertile overweight women with PCOS
- Trial name
- NCT01279512
- Testing
- Metformin, Acarbose
- Where
- Iran
- Volunteers
- 50 people
- Sponsor
- Royan Institute