Clinical trials: PCOS
Polycystic Ovary Syndrome
Effects of Metformin vs Oral Contraceptives on CV Risk Markers in PCOS
Cardiovascular risk factors cluster in hyperandrogenic women - including those presenting with the polycystic ovary syndrome - in association with insulin resistance, obesity, and other metabolic disorders.
- Trial name
- NCT00428311
- Testing
- Metformin, Ethynyl-estradiol plus cyproterone acetate
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Ramon y Cajal
Polycystic Ovary Syndrome
Lifestyle Change in Women With Polycystic Ovary Syndrome
This project aims to compare "diet" and "diet and exercise combination" interventions in obese women with polycystic ovary syndrome.
- Trial name
- NCT05377021
- Testing
- Lifestyle change
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Polycystic Ovary Syndrome, Diminished Ovarian Reserve
Clinical Trial of Anovulatory Infertility
This project aims to study the expression of clock genes and related proteins in follicular fluid and granulosa cells, depicting the periodic, amplitude, and phase changes of biological clock genes and related proteins in women…
- Conditions
- Polycystic Ovary Syndrome, Diminished Ovarian Reserve, Ovulation Disorder
- Trial name
- NCT06601452
- Testing
- a compound prescription of Chinese medicine
- Where
- China
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Affiliated Hospital of Nanjing University of Chinese Medicine
Polycystic Ovary Syndrome, Exercise
The Effects of High-intensity and Moderate-intensity Exercise on Polycystic Ovary Syndrome
This study will investigate the impact of high- and moderate-intensity exercise on the cardiometabolic and brain health of women with Polycystic Ovary syndrome (PCOS).
- Conditions
- Polycystic Ovary Syndrome, Exercise, Cerebrovascular Circulation
- Trial name
- NCT05394935
- Testing
- High-Intensity Exercise, Moderate-Intensity Exercise
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Cardiff Metropolitan University
Polycystic Ovary Syndrome (PCOS)
Fertility and Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder among women of reproductive age and affects approximately 10% of women worldwide.
- Trial name
- FERTIOPK (NCT07499518)
- Testing
- Questionnaires
- Where
- France
- Volunteers
- 473 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Obesity, Polycystic Ovary Syndrome
Mindfulness-based Stress Reduction in Obese Women With Polycystic Ovary Syndrome (PICOS)
The aim of this study was to evaluate the effects of a mindfulness-based stress reduction (MBSR) program on Stress, depression, anxiety, cognitive triad and emotional appetite in obese women with polycystic ovary syndrome (PCOS).
- Conditions
- Obesity, Polycystic Ovary Syndrome, Stress
- Trial name
- NCT06665789
- Testing
- Mindfulness-based Stress Reduction
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Polycystic Ovary Syndrome
The Phenotype and Clinical Intervention of High BCAA Type of PCOS
Polycystic ovary syndrome is one of the main diseases leading to infertility in women of childbearing age. In addition to endocrine and reproductive dysfunction, it is often accompanied by significant metabolic abnormalities…
- Trial name
- BCAAPCOS (NCT06192147)
- Testing
- protein restricted diet combined with vitamin D intervention
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Polycystic Ovary Syndrome, Irregular Menses
Effect Of Treadmill Based Aerobic Exercise Intervention On Menstruation And Quality Of Life In Women With Polycystic Ovarian Syndrome
this study will be carried to investigate the effect of aerobic exercise on menstrual regularity and quality of life in pco women
- Trial name
- NCT04744948
- Testing
- Treadmill exercise, low caloric diet
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Polycystic Ovary Syndrome, Dental Caries
Oxidative Stress in Polycystic Ovary Syndrome With Periodontal Disease and Dental Caries Lesions
This study evaluates the oxidative stress parameters in females with polycystic ovary syndrome (PCOS) and clinically healthy. Because of the fact that both oral disease included periodontitis and dental caries, and metabolic…
- Trial name
- NCT03594968
- Testing
- polycystic ovary syndrome
- Where
- Turkey (Türkiye)
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
PCOS, Insulin Resistance
Effects of Simvastatin and Micronized Trans-resveratrol Treatment on Polycystic Ovary Syndrome (PCOS) Patients
Polycystic ovary syndrome (PCOS) is the most common endocrinopathy affecting women of reproductive age. Hyperandrogenism is the central feature of PCOS.
- Trial name
- NCT02766803
- Testing
- Simvastatin and micronized trans-resveratrol
- Where
- Poland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Poznan University of Medical Sciences
PCOS
Exogenous Ketone Supplementation in Females with Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) affects 1 in 5 females of reproductive age. Commonly characterized as a disorder of infertility, PCOS is often accompanied by 3 potent cardiovascular disease (CVD) risk factors: insulin…
- Trial name
- NCT06155708
- Testing
- Ketone, Water
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- McGill University
Polycystic Ovary Syndrome, Healthy Pregnant Women
Androgen Metabolism and Reproductive Outcome
The aim of this study is to determine maternal androgen metabolism during pregnancy and the impact of androgen disorders on mothers and infants.
- Trial name
- NCT02106676
- Where
- Austria
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Normal, PCOS
Determining How Quickly Progesterone Slows LH Pulse Frequency
The rapidity with which progesterone (P) suppresses daytime lutenizing hormone (LH) (and by inference gonadotropin releasing hormone (GnRH)) pulse frequency is unknown.
- Trial name
- CRM001 (NCT00594217)
- Testing
- oral micronized progesterone suspension
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Polycystic Ovary Syndrome, Non-Alcoholic Fatty Liver Disease
Efficacy of Canagliflozin Versus Metformin in Women With Polycystic Ovary Syndrome
The goal of this clinical trial is to investigate the use of ultra-high performance liquid chromatography-mass spectrometry for metabolomics and proteomics research in patients with Polycystic Ovary Syndrome (PCOS) and…
- Trial name
- NCT06256289
- Testing
- Canagliflozin 100mg Tab, Metformin Hydrochloride
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ping Li,MD
Polycystic Ovarian Syndrome
Polycystic Ovarian Syndrome: Impact of Flaxseed Supplementation
The overall aim of this study is to explore the effects of flaxseed supplementation and determine whether it is a feasible and potentially effective dietary intervention among women with polycystic ovarian syndrome (PCOS).
- Trial name
- NCT00693082
- Testing
- flaxseed
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Duke University
Polycystic Ovary Syndrome (PCOS)
Protein and Polycystic Ovary Syndrome (PCOS)
Polycystic ovary syndrome (PCOS) is a significant public health problem and is one of the most common hormonal disturbances affecting women of reproductive age.
- Trial name
- NCT07158723
- Testing
- Higher protein dietary pattern, Calorie restriction
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Arkansas, Fayetteville
Polycystic Ovary Syndrome
Effect of Meal Composition on Postprandial Testosterone Concentration in Women With Polycystic Ovary Syndrome
The primary objective is to determine if meals of different fat and fiber content affect postprandial plasma testosterone concentration in women with polycystic ovary syndrome.
- Trial name
- NCT00455338
- Testing
- Meal Composition
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Polycystic Ovary Syndrome, Insulin Resistance
The Role of Insulin Resistance in PCOS
Polycystic ovary syndrome (PCOS) phenotype can be structured into three components: anovulation, hyperandrogenism and the metabolic syndrome (of which hyperinsulinemia, secondary to insulin resistance, is the central…
- Conditions
- Polycystic Ovary Syndrome, Insulin Resistance, Obesity
- Trial name
- NCT00173043
- Where
- Taiwan
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
PCOS
Bisphenol Role in the Pathogenesis of PCOS
Polycystic ovary syndrome (PCOS) is the most common and the most heterogeneous endocrine disorder in premenopausal women. Its prevalence is estimated from 5 to 10% depending on the diagnosis' criteria .
- Trial name
- NCT03436108
- Testing
- Measurement of Bisphenol in urine
- Where
- Egypt
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Aljazeera Hospital
Polycystic Ovary Syndrome
Acupuncture for Polycystic Ovarian Syndrome
This is a randomized control trial of acupuncture for women with polycystic ovary syndrome. The study is triple-blinded.
- Trial name
- NCT00602940
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of Virginia