Clinical trials: PCOS (Polycystic Ovary Syndrome)
Cardiovascular Diseases
Primary Ovarian Insufficiency, Polycystic Ovary Syndrome & the CardiOvascular Risk Profile
The polycystic ovary syndrome (PCOS) is the most common endocrinopathy amongst women of reproductive age. PCOS is associated with various cardiovascular risk factors such as obesity, glucose intolerance, dyslipidemia hypertension…
- Trial name
- POPCORn (NCT02616510)
- Testing
- cardiovascular screening
- Where
- Netherlands
- Volunteers
- 125 people
- Sponsor
- UMC Utrecht
PCOS
Eye Evaluation in Patients With PCOS
To evaluate the macular, retinal nerve fiber layer (RNFL) and choroidal thickness alterations by using spectral-domain optical coherence tomography (SD-OCT) in polycystic ovary syndrome (PCOS) and to compare them with healthy…
- Trial name
- NCT01950832
- Testing
- Investigating clinically normal patients with optic coherence tomography
- Where
- Turkey (Türkiye)
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Gökhan Açmaz
Anovulation, Obesity
An RCT of Metformin Vs Orlistat in Obese Anovulatory Women
This study aims to investigate the role of the weight reduction agent, Orlistat compared to the Metformin for the management of women who are obese and do not ovulate or have difficulty conceiving.
- Trial name
- NCT00292799
- Testing
- Orlistat Vs Metformin
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Insulin Resistance
Brain Metabolism in Polycystic Ovary Syndrome
The purpose of this study is to investigate whether higher insulin resistance in young women with Polycystic ovary syndrome (PCOS) is associated with reduced cerebral metabolic rate of glucose (CMRglu).
- Trial name
- NCT02409914
- Volunteers
- 7 people
- Sponsor
- Université de Sherbrooke
Subfertility, Female
OCP Pretreatment in PCOS Patients Undergoing ICSI Using Antagonist Protocol
373 women with PCOS undergoing a trial of IVF/ICSI will receive OCP from day 2 of the preceding cycle for 21 days followed by GnRH antagonist COH.
- Trial name
- NCT03881904
- Testing
- 0.075mg gestodene/0.03mg ethinylestradiol
- Where
- Egypt
- Volunteers
- 740 people
- Sponsor
- Ain Shams University
Reproductive Age, PCOS (Polycystic Ovary Syndrome)
Functional Proteins in Polycystic Ovary Syndrome
The concentration of functional proteins: kisspeptin, ghrelin, zonulin will be measured and compared in women with polycystic ovary syndrome (PCOS) and insulin resistance (IR), in women with PCOS without IR, and in women without…
- Trial name
- NCT06793098
- Testing
- Measurement of kisspeptin concentration, Measurement of ghrelin concentration, Measurement of zonulin concentration
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Jagiellonian University
Polycystic Ovary Syndrome
Time-Restricted Eating as a Dietary Intervention for Polyendocrine Metabolic Ovarian Syndrome (PMOS): Protocol for a Randomized Controlled Trial
Polyendocrine Metabolic Ovarian Syndrome (PMOS), previously known as PCOS, is a common endocrine disorder associated with metabolic, reproductive, and hormonal abnormalities.
- Trial name
- NCT06204965
- Testing
- Time-restricted eating
- Where
- Poland
- Volunteers
- 84 people
- Sponsor
- Joanna Bajerska
Polycystic Ovary Syndrome
Clinical and Biochemical Presentation of Polycystic Ovary Syndrome in Different Age Group
To study the clinical and biochemical characteristics women with polycystic ovary syndrome (PCOS) in different aged groups.
- Trial name
- NCT01350895
- Where
- Taiwan
- Volunteers
- 781 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University WanFang Hospital
PCOS (Polycystic Ovary Syndrome)
MeDiApp-PCOS: A Mobile Mediterranean Diet App for Women With Polycystic Ovary Syndrome
This randomized clinical trial will test whether a mobile application with personalized Mediterranean diet-based recommendations can improve health outcomes in women with polycystic ovary syndrome compared with standard lifestyle…
- Trial name
- MeDiApp-PCOS (NCT07598344)
- Testing
- Mobile Application-Based Personalized Mediterranean Diet and Lifestyle Intervention, Standard Lifestyle Advice for PCOS
- Volunteers
- 60 people
- Sponsor
- Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health
Polycystic Ovary Syndrome
Taichi for Overweight/Obese Adolescent and Young Women With Polycystic Ovary Syndrome (PCOS)
The present study is a randomized pilot study, overweight/obese adolescent and young PCOS subjects will be assigned into two groups: Taichi arm and control arm. Hormonal profile and metabolic profile will be determined.
- Trial name
- NCT02608554
- Testing
- Taichi, Self-monitored exercise
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Heilongjiang University of Chinese Medicine
Obesity, Polycystic Ovary Syndrome
Mindfulness-based Stress Reduction in Obese Women With Polycystic Ovary Syndrome (PICOS)
The aim of this study was to evaluate the effects of a mindfulness-based stress reduction (MBSR) program on Stress, depression, anxiety, cognitive triad and emotional appetite in obese women with polycystic ovary syndrome (PCOS).
- Conditions
- Obesity, Polycystic Ovary Syndrome, Stress
- Trial name
- NCT06665789
- Testing
- Mindfulness-based Stress Reduction
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Polycystic Ovary Syndrome
Ovarian Morphology and Theca Cell Androgen Production in Women With Polycystic Ovary Syndrome (PCOS)
Women with PCOS suffer from excess male hormone (androgen) production by the ovary. Androgen is made by cells that surround follicles that contain eggs.
- Trial name
- NCT02145247
- Testing
- hCG
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Polycystic Ovary Syndrome
PCOS Indirect and Intangible Economic Burden
The primary purpose of the PCOS Indirect and Intangible Economic Buren study is to estimate the economic costs of having PCOS in terms of quality of life and work productivity.
- Trial name
- PCOSCHALLENGE (NCT05903404)
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- PCOS Challenge: The National Polycystic Ovary Syndrome Association
Polycystic Ovary Syndrome, Menstrual Problem
Myoinositol Plus L-tyrosine, Selenium and Chromium in PCOS
PCOS patients were treated every day, with one sachet containing 2000 mg myo-inositol, 500 mg L-tyrosine, 40 mcg chromium picolinate, 55 mcg selenium, 200 mcg folic acid.
- Conditions
- Polycystic Ovary Syndrome, Menstrual Problem, Hirsutism
- Trial name
- NCT03673995
- Testing
- Myo-inositol+L-tyrosine
- Where
- Italy
- Volunteers
- 186 people
- Sponsor
- Pharmarte srl
Ovary Cyst, Fertility Issues
Dydrogesterone-Primed Ovarian Stimulation Protocol Versus Gonadotropin Releasing Hormone Antagonist Protocol in ICSI
GnRH antagonist protocol is currently a good strategy for controlled ovarian stimulation in women with PCOS undergoing IVF/ICSI cycles.
- Trial name
- NCT05751681
- Testing
- progestin primed ovarian stimulation protocol, dydrogesterone (Duphaston, Abbott), Cetrotide
- Where
- Egypt
- Volunteers
- 79 people
- Sponsor
- Zagazig University
Polycystic Ovary Syndrome
The Impact of Polycystic Ovary Syndrome (PCOS) on Quality of Life and Healthcare Beliefs
Women with Polycystic Ovary Syndrome (PCOS) between the age of 18 and 55 are being recruited to participate in an online survey to determine the impact of PCOS on quality of life and interaction with the healthcare system.
- Trial name
- PCOS (NCT00961688)
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Georgia Reproductive Specialists
Polycystic Ovary Syndrome
Cortisol Regulation in Polycystic Ovary Syndrome (PCOS)
The purpose of this study is to determine if insulin resistance (how well the body uses insulin and clears sugar) can affect cortisol levels in normal healthy women and women with polycystic ovary syndrome of all body weights.
- Trial name
- NCT00694759
- Testing
- pioglitazone, metformin
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Polycystic Ovary Syndrome, Vitamin D Deficiency
The Effects of Vitamin D on Angiogenic Factors in Women With Polycystic Ovary Syndrome
Polycystic Ovary Syndrome (PCOS) affects 5 to 10% of women of reproductive age. It is characterized by a cluster of hyperandrogenism, hyperinsulinemia, menstrual dysfunction, hirsutism and infertility.
- Trial name
- NCT02460380
- Testing
- Vitamin D3
- Volunteers
- 93 people
- Sponsor
- Maimonides Medical Center
Polycystic Ovary Syndrome, Anovulation
Effect of Vitamin D on Ovulation Rate in Women With Polycystic Ovary Syndrome
This is a randomized double-blind controlled trial on the effect of vitamin D supplementation to assess the ovulation rate of women with polycystic ovary syndrome (PCOS) and other reproductive, endocrine and metabolic outcomes…
- Trial name
- NCT04650880
- Testing
- Vitamin D
- Where
- 3 sites in Hong Kong
- Volunteers
- 220 people
- Sponsor
- The University of Hong Kong
PCOS
Myo-inositol Versus D-chiro-inositol in the Treatment of Polycystic Ovary Syndrome and Insulin Resistance: Evaluation of Clinical, Metabolic, Endocrine and Ultrasound Parameters
Insulin resistance has important implications in the pathogenesis of the polycystic ovary syndrome (PCOS) and insulin-sensitizing drugs are considered a useful therapeutic approach.
- Trial name
- NCT01514942
- Testing
- Myo-inositol + Folic acid, D-chiro-inositol, manganese, folic acid, vit B12, Folic acid, vit B12
- Where
- Italy
- Sponsor
- AGUNCO Obstetrics and Gynecology Centre
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