Clinical trials: PCOS (Polycystic Ovary Syndrome)
Polycystic Ovary Syndrome
Repeated Doses of GnRH Agonist as Oocyte Triggering in Antagonist Protocol for Patients With Polycystic Ovary Syndrome
This is a prospective, randomized, proof-of-concept study, designed to compare the IVF results in patients diagnosed with polycystic ovarian syndrome (PCOS) defined as per the ESHRE/ASRM Rotterdam criteria (2003) undergoing…
- Trial name
- NCT04600986
- Testing
- Repeated dose of GnRH agonist
- Where
- Iran
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Royan Institute
Polycystic Ovary Syndrome
The Study of Polycystic Ovary Syndrome (PCOS) and Questionnaire
Polycystic ovary syndrome (PCOS) is an extremely common disorder in women of reproductive age. Diagnosis of PCOS is principally based on clinical and physical findings.
- Trial name
- NCT01256970
- Where
- Taiwan
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University WanFang Hospital
Polycystic Ovary Syndrome
The Effect of Polycystic Ovary Syndrome Treatment on Metabolomics
The aim of this study is to determine the effect of the treatment of polycystic ovary syndrome with two different oral contraceptives that contain cyproterone acetate and drospirenone
- Trial name
- NCT04831151
- Testing
- Yasmin, Diane-35
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Inonu University
Polycystic Ovary Syndrome (PCOS), Overweight
The Effect of GLP-1 Agonists Versus OCs on Reproductive Disorders and Cardiovascular Risks in Overweight PCOS
Polycystic ovary syndrome (PCOS) is a health problem that affects one in 10 women of childbearing age, which is usually characterized by hormonal imbalance and metabolism problems such as hyperandrogenism and obesity.
- Conditions
- Polycystic Ovary Syndrome (PCOS), Overweight, Obesity
- Trial name
- NCT03151005
- Testing
- Metformin-GLP-1 Receptor Agonist, Metformin-Oral Contraceptive(OC)
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Xinqiao Hospital of Chongqing
Quality of Life
Anxiety and Sexual Malfunction Functions in Infertile Pcos Women
Polycystic ovary syndrome (PCOS) is a common hormonal disorder in females in reproductive age associated with signs and symptoms as amenorrhea or oligomenorrhea, obesity,infertility acne and hirsutism tism that mostly Reduce self…
- Trial name
- NCT05056272
- Where
- Egypt
- Volunteers
- 129 people
- Sponsor
- Assiut University
Polycystic Ovary Syndrome
Effects of Inositol Alone or Associated With Alpha-lipoic Acid in Polycystic Ovary Syndrome Treatment
The aim of this double-blinded, three-armed randomized controlled trial (RCT) is to evaluate the effects of a 6 months treatment with inositol alone or inositol associated with alpha-lipoic acid in women with polycystic ovary…
- Trial name
- IALA (NCT04881851)
- Testing
- Inositol + alpha lipoic acid, Inositol
- Where
- Italy
- Volunteers
- 76 people
- Sponsor
- Universita di Verona
Polycystic Ovary Syndrome
A Multi-omic Approach to Evaluate and Characterize the Polycystic Ovary Syndrome (PCOS) Phenotype
The purpose of this research study is to explore the relationship between the gut microbiome and hormone levels in women diagnosed with PCOS and determine whether there are differences in the gut microbiome between women with…
- Trial name
- NCT04981275
- Testing
- No intervention study
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Onegevity Health
Polycystic Ovary Syndrome
Comparison Between Laparoscopic Ovarian Diathermy and Clomiphene Citrate in Women With Anovulatory PCOS
Laparoscopic ovarian diathermy (LOD) is currently offered to infertile women with polycystic ovarian syndrome (PCOS) who fail to conceive on clomiphene citrate (CC).
- Trial name
- NCT00220545
- Testing
- Laparoscopic ovarian diathermy
- Where
- United Kingdom
- Volunteers
- 72 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Polycystic Ovary Syndrome
SGLT2 Inhibitors in Treating Patients With PCOS
Chronic inflammation is the core of Polycystic ovary syndrome (PCOS), and obesity and overweight further exacerbate the level of inflammation in the peripheral circulation and ovarian tissue in PCOS patients.
- Trial name
- NCT05966792
- Testing
- SGLT2 inhibitors, metformin
- Where
- China
- Volunteers
- 82 people
- Sponsor
- Shanghai 10th People's Hospital
Polycystic Ovary Syndrome (PCOS), Menstrual Irregularity
Nutritional and Metabolic Correlates of Ovarian Morphology in Women With Polycystic Ovary Syndrome
The investigators would like to determine how aspects of metabolism and age influence ovarian function. The purpose of the study is to understand how nutrition and metabolism relate to follicle development in women with regular…
- Trial name
- NCT01927471
- Where
- 3 sites in United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Cornell University
PCOS (Polycystic Ovary Syndrome)
Effect of Combined Hormonal Contraceptiveson Free Androgen Index (FAI) in Polycystic Ovary Syndrome:Drospirenone-Ethinyl Estradiol (DRSP-EE) Versus Cyproterone Acetate-Ethinyl Estradiol (CPA-EE)
The goal of this clinical trial is to learn if drug Drospirenone ethinyl estradiol works better than drug Cyproterone acetate ethinyl estradiol to treat PCOS.
- Trial name
- PCOS FAI CHC (NCT07911709)
- Testing
- DRSP-EE (Experimental) group received DRSP-EE 1 tab daily (one active pill daily for 21 days and 7 inactive pills) for three cycles, .CPA-EE (Comparator) groupreceivedCPA-EE 1 tab daily (one active pill daily for 21 days and 7 pill free days) for three cycles
- Where
- Bangladesh
- Volunteers
- 60 people
- Sponsor
- Mst.Sumyara Khatun
Polycystic Ovary Syndrome (PCOS)
Androgen Excess as a Cause for Adipogenic Dysfunction in PCOS Women
The purpose of this research study is to collect specimen samples and study medical information from women with Polycystic Ovary Syndrome (PCOS) and women without PCOS.
- Trial name
- NCT01889199
- Testing
- Flutamide
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Polycystic Ovary Syndrome
Efficacy of Jianpi Qushi Huatan Decoction in the Treatment of Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is a common reproductive disease associated with endocrine and metabolic disorders. Some studies have shown that Chinese herbal medicine is beneficial for PCOS, but the efficacy of Chinese herbal…
- Trial name
- NCT05976295
- Testing
- Jianpi Qushi Huatan Decoction
- Where
- China
- Volunteers
- 68 people
- Sponsor
- Jiangxi University of Traditional Chinese Medicine
Obesity, Polycystic Ovary Syndrome
Treatment of Obesity With Topiramate in Patients With Polycystic Ovary Syndrome
Treatment of obesity related to Polycystic Ovary Syndrome with topiramate or placebo to assess improvement of clinical and laboratory parameters after 6 months of follow-up
- Conditions
- Obesity, Polycystic Ovary Syndrome, Hyperandrogenism
- Trial name
- NCT04453306
- Testing
- Topiramate
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Adverse Effect of Oral Contraceptives, Sequela
Contraceptive Pill and Hormonal Vaginal Ring in Women With Polycystic Ovary Syndrome
The main aims of this study are: to investigate and compare the effects of long lasting use (59 weeks) of vaginal and oral contraceptives on androgen secretion, insulin and glucose metabolism, lipid profile, and serum levels of…
- Trial name
- NCT01588873
- Testing
- oc:E-E-desogestrel/vaginal ring:E-E -ethonogestrel
- Where
- Finland
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Oulu
Polycystic Ovarian Syndrome (PCOS)
BRCC36 and Telomerase Levels in Women With Polycystic Ovary Syndrome
This prospective observational case-control study evaluated serum BRCC36 and telomerase (TE) levels in women with polycystic ovary syndrome (PCOS) and healthy controls. Women aged 18-43 years were included.
- Trial name
- NCT07849166
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Polycystic Ovarian Syndrome (PCOS)
Effect of Coenzyme Q10 Administration on Polycystic Ovary Syndrome
The goal of this clinical trial is to determine the effects of coenzyme Q10 supplementation on oxidative stress, inflammation and hyperandrogenism in women with polycystic ovary syndrome.
- Trial name
- PCOS (NCT06659406)
- Testing
- Coenzyme Q10
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- University of Faisalabad
Polycystic Ovary Syndrome, Infertility, Female
Effect of ALA Combined With Letrozole on Polycystic Ovary Syndrome Clinical Outcome in Infertile Females
This research study aims to investigate the effect of adding Alpha lipoic acid (ALA) supplement to letrozole treatment in infertile women with polycystic ovary syndrome (PCOS).
- Trial name
- NCT06418347
- Testing
- Alpha lipoic acid, Letrozole
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Ain Shams University
Polycystic Ovary Syndrome
The PCOS Challenge Study
The primary purpose of The PCOS Challenge Study will be to conduct high-quality research where patients are included in the design, and answering the questions that patients identify as important to their lived experience with…
- Trial name
- PCOSCHALLENGE (NCT05797909)
- Where
- United States
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- PCOS Challenge: The National Polycystic Ovary Syndrome Association
Vitamin D Deficiency, Clomiphene Allergy
Effect of Vitamin D Oral Supplementation in Poly Csytic Ovarian Women Resistant to Clomiphene Citrate
effect of vitamin D oral supplementation in poly csytic ovarian women resistant to clomiphene citrate
- Conditions
- Vitamin D Deficiency, Clomiphene Allergy, Polycystic Ovary Syndrome
- Trial name
- NCT04916925
- Testing
- Vitamin D, Clomid
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- rana alaaeldin aly ibrahim nasr
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