Clinical trials: PCT
Severe Acute Malnutrition
Ready to Use Therapeutic Food (RUTF) in Severe Malnourished Children
1. RUTF would be more effective (quicker catch-up growth by promoting more tissue accrue resulting decrease stay in rehabilitation ward) in treating children with SAM during the rehabilitation phase than khichuri /halwa; 2.
- Trial name
- RUTF (NCT01331044)
- Testing
- Plumpy Nut, Khichuri and Halwa
- Where
- Bangladesh
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Anemia, Blood Transfusion
A Study of the Safety and Effectiveness of Epoetin Alfa in Facilitating Self-donation of Blood Before Surgery in Patients Who Are Undergoing Orthopedic Surgery and Who Have Low Hematocrit Levels (the Percent of Red Blood Cells in Whole Blood)
The purpose of this study is to evaluate the safety and effectiveness of epoetin alfa and to determine whether epoetin alfa will facilitate self-donation of blood before surgery in patients who have anemia, (as indicated by low…
- Conditions
- Anemia, Blood Transfusion, Orthopedic Procedures
- Trial name
- NCT00270114
- Testing
- epoetin alfa
- Volunteers
- 55 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Early-Onset Neonatal Sepsis
PROcalcitonin and Presepsin-guided Decision for Antibiotic Prophylaxis of EOS
The goal of this randomized controlled study is to compare the outcome of preterm infants who will receive the standard antibiotic prophylaxis for EOS or Procalcitonin/Presepsin-guided antibiotic prophylaxis of early onset sepsis…
- Trial name
- PROPOSE (NCT05796115)
- Testing
- Procalcitonin/Presepsin guided antibiotic prophylaxis for EOS, Antibiotic prophylaxis for EOS
- Volunteers
- 266 people
- Sponsor
- University of Florence
Locally Advanced or Metastatic Medullary Thyroid Cancer, Medullary Thyroid Cancer
Study to Determine if Contacting Patients With MTC More Frequently Results in Earlier Detection and Treatment of Signs and Symptoms of AEs and Thus a Decrease in the Percentage of Time Patients Experience AEs During First 12 Months on Vandetanib Treatment
The purpose of this study is to evaluate the effect of patient outreach program on the proportion of time patients with MTC experience moderate or severe AEs during first 12 months of treatment with vandetanib
- Trial name
- NCT01298323
- Testing
- Patient outreach, Vandetanib
- Where
- 66 sites in Australia, Austria and 18 more
- Volunteers
- 205 people
- Sponsor
- Sanofi
Sepsis, Intensive Care
Procalcitonin Guided Versus Conventional Antibiotic Therapy in Patients With Sepsis in the ICU
The adequacy of early empiric antimicrobial therapy is an important factor in determining the outcome in patients with severe sepsis. The duration of adequate antibiotic therapy in these patients however is less clear.
- Trial name
- NCT00987818
- Testing
- Procalcitonin measurement
- Where
- Netherlands
- Sponsor
- Rijnstate Hospital
Obesity
Evaluation of the Accuracy of a Computer Vision-based Tool for Assessment of Total Body Fat Percentage
This research study is designed to validate the precision and accuracy of body measurement and composition results from a novel 2D imaging device that operates through a smart-phone application.
- Trial name
- MEASURE (NCT04854421)
- Testing
- VBC
- Where
- 2 sites in United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Gout
The Percentage of Cases of Acute Treatment With Allopurinol in Gout Patients
The aim of the study is to determine the percentage of cases of acute treatment with Allopurinol in gout patients who have been previously treated.
- Trial name
- NCT03601260
- Testing
- Allopurinol
- Where
- Israel
- Volunteers
- 700 people
- Sponsor
- Hillel Yaffe Medical Center
Head and Neck Neoplasms
Accuracy and Safety of Coplanar Template Assistance for Head and Neck Biopsies.
This is a prospective single-arm cohort study to evaluate the accuracy and safety of three-dimensional printing co-planer template(3D-PCT) for computed tomography (CT)-guided neck and head biopsy .
- Trial name
- NCT05396183
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking University Third Hospital
Anastomotic Leak
Role of Procalcitonin, C-Reactive Protein, and WBC Count in Prediction of Colorectal Anastomotic Leak
The interest in identifying a biological marker for the early detection of AL is growing. Such a marker could play a vital role in modern fast-track multimodal protocols, allowing safe and early discharge of patients after…
- Trial name
- NCT05159024
- Testing
- CRP, PCT, and WBCs trajectories
- Where
- Egypt
- Volunteers
- 205 people
- Sponsor
- Suez Canal University
Myelodysplastic Syndromes (MDS)
A Prospective, Multicentre European Registry for Newly Diagnosed Patients With Myelodysplastic Syndromes
Study Objectives: To collect and describe demographics, disease-management, and treatment outcomes of Myelodysplastic Syndromes (MDS) patients who are newly diagnosed and classified according to the World Health Organization…
- Trial name
- EUMDS (NCT00600860)
- Testing
- No interventions
- Where
- 18 sites in Austria, Croatia and 16 more
- Volunteers
- 4,000 people
- Sponsor
- Radboud University Medical Center
Pneumonia
Procalcitonin Use in Pneumonia Patients in the Critical Care Setting
The goal of the study is to determine the impact of procalcitonin (PCT)-guided therapy on duration of antibiotic therapy in critical care unit (CCU) patients with suspected pneumonia at Mayo Clinic Health System Eau Claire.
- Trial name
- NCT01788488
- Testing
- Use of procalcitonin as biomarker to guide therapy
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- Mayo Clinic
Percent of Vocal Cords (Glottic) Opening
Vocal Cord Views With the Classical Miller, Wis-Hipple and C-MAC Size 1 Blades in Young Children
The purpose of this study is to compare straight blades in obtaining best vocal cord view in children. The investigators will compare size 1 Classical Miller, size 1 Wis-Hipple, and size 1 C-MAC straight blades in young children.
- Trial name
- POGO (NCT03053583)
- Testing
- Laryngoscope blade
- Volunteers
- 96 people
- Sponsor
- State University of New York at Buffalo
Severe Sepsis, Septic Shock
Prognostic Evaluation Of Severe Sepsis And Septic Shock. Procalcitonin Versus Delta Sofa
The purpose of this study is to compare the tendency of plasma concentration and clearance of procalcitonin in the first 24 and 48 hours of management of patients with severe sepsis and septic shock with another marker of early…
- Trial name
- NCT01841190
- Where
- 2 sites in Brazil
- Volunteers
- 128 people
- Sponsor
- Hospital Sao Domingos
Infections, Cancer
Procalcitonin as a Marker of Infection in Cancer Patients
Infections pose a serious threat to cancer patients in chemotherapy. Prompt diagnosis and treatment is of paramount importance as infections may be life-threatening in immune-compromised individuals.
- Conditions
- Infections, Cancer, Procalcitonin, C Reactive Protein
- Trial name
- NCT01227109
- Where
- 2 sites in Denmark
- Volunteers
- 80 people
- Sponsor
- Herlev Hospital
Colorectal (Colon or Rectal) Cancer, STOMACH NEOPLASM
Perioperative Biomarkers in Colorectal and Gastric Cancer Surgery
This study aims to evaluate whether monitoring perioperative inflammatory and metabolic biomarkers can help identify postoperative complications early in adult patients undergoing colorectal or gastric cancer surgery.
- Trial name
- PERIO-BIO (NCT07881133)
- Testing
- Perioperative Biomarker-Guided Monitoring
- Where
- Romania
- Volunteers
- 320 people
- Sponsor
- Bucharest Emergency Hospital
Percentage of Deep Bite Correction
Assessment of Changes in Labioincisal Relationship in Deep Bite Correction by Twin Slot Orthodontic Bracket Clinical Trial Study.
Assessment Changes in Labio incisal Relationship in Deep bite Correction by Twin Slot Orthodontic Bracket; clinical trial study.
- Trial name
- NCT06677619
- Testing
- intrusion by reverse curve wire in cervical position of twin slot bracket
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Faculty of Dental Medicine for Girls
Spinal Cord Injuries
FES Cycling and Nutritional Counseling for Battling Obesity After SCI
Individuals who suffer from paralysis after spinal cord injury (SCI) are estimated to have an even greater (66%) prevalence of obesity.
- Trial name
- NCT03810963
- Testing
- HIIT-FES Cycling combined with Nutritional Counseling, Nutritional Counseling Only
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- William Carey University
Helicobacter Pylori Infection
Standardize Communication With General Practitioner & Patient for Improved Eradication of Helicobacter Pylori
Patients who test Helicobacter pylori positive, are treated with antibiotics. However, due to a number of factors (such as unknown treatment compliance, no standardized follow-up, ...), a relative low eradication-percentage was…
- Trial name
- Helipro (NCT02873247)
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Meningitis, Meningococcal, Meningococcal Sepsis
Petechiae In Children (PIC) Study: Defining A Clinical Decision Rule for The Management Of Fever and Non-Blanching Rashes In Children Including The Role Of Point Of Care Testing For Procalcitonin & Neisseria Meningitidis DNA.
A fever and a non-blanching rash is a relatively common reason for a child to attend an emergency department. A fever and a non-blanching rash can be an early sign of a life-threatening infection known as meningococcal disease.
- Conditions
- Meningitis, Meningococcal, Meningococcal Sepsis, Meningococcal Disease, Meningococcal Infections
- Trial name
- PIC (NCT03378258)
- Where
- United Kingdom
- Volunteers
- 1,329 people
- Sponsor
- Belfast Health and Social Care Trust
Chronic Obstructive Lung Disease
Procalcitonin To Reduce Antibiotics in Chronic Obstructive Lung Disease (ProToCOLD)
Title: Pro-to-COLD, Procalcitonin to Chronic Obstructive Lung Disease, COLD: Chronic Obstructive Lung Disease, Regarding: Patients hospitalized with suspected acute exacerbation of COPD + / - pneumonia.
- Trial name
- ProToCOLD (NCT01950936)
- Testing
- Discontinuation of Antibiotcs
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- Danish Procalcitonin Study Group