Clinical trials: PCT
Neonatal Sepsis, Early-Onset
Performance of Interleukin-27 Cord Blood Level as A Biomarker Predicating Early Onset Neonatal Sepsis
Neonatal sepsis still considered as one of the major causes of mortality and morbidity during the neonatal period due to high vulnerability of that age group.
- Trial name
- NCT05589909
- Testing
- IL27, PCT, CRP, Blood culture
- Where
- United Arab Emirates
- Volunteers
- 548 people
- Sponsor
- Mansoura University Children Hospital
Sepsis
A Clinical Trial of Procalcitonin-guided Antimicrobial Therapy in Sepsis
The aim of the study is to demonstrate if using one procalcitonin (PCT)-guided rule of stop of antimicrobials, the incidence of infections by C.difficile and by Multi-Drug-Resistant (MDR) bacteria during the next six months may…
- Trial name
- PROGRESS (NCT03333304)
- Testing
- Procalcitonin measurement
- Where
- 7 sites in Greece
- Volunteers
- 266 people
- Sponsor
- Hellenic Institute for the Study of Sepsis
Acute Pyelonephritis
Accuracy of Infection Biomarkers in the Investigation of Patients With Suspected Acute Pyelonephritis
The aim of this study is to investigate the diagnostic and prognostic value of C-reactive protein (CRP), serum procalcitonin (PCT) and soluble urokinase plasminogen activator receptor (suPAR) in the initial investigation of…
- Trial name
- NCT04686318
- Testing
- Biomarkers for acute pyelonephritis
- Where
- Denmark
- Volunteers
- 229 people
- Sponsor
- University of Southern Denmark
Being a 5th Year Student at the Faculty of Medicine, No Previous Laryngoscopy Experience
THE EFFECTS OF DIRECT AND INDIRECT LARYNGOSCOPY ON CORMACK-LEHANE AND POGO SCORES
Direct laryngoscopy (DL) is a conventional and highly difficult method that is used in endotracheal intubation (ETI) training. Today, the usage of video-laryngoscopes (VLs) to teach airway management to inexperienced healthcare…
- Trial name
- NCT06327958
- Testing
- Cormack-Lehane (C&L), POGO score
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Overweight and Obesity, T2DM (Type 2 Diabetes Mellitus)
Effect of Viscous Soluble Fibres on Body Weight
Abstract: Background: Obesity is a global pandemic affects all age groups and is independent risk factors for most chronic diseases. Dietary intervention is an essential component of obesity management.
- Conditions
- Overweight and Obesity, T2DM (Type 2 Diabetes Mellitus), General Population
- Trial name
- NCT03257449
- Testing
- Viscous Fibre
- Where
- Canada
- Volunteers
- 1,268 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Intrathecal Infection, External Ventricular Drainage Associated Infection
Cerebrospinal Fluid IL-6, IL-8 and PCT as Early Marker of an Intrathecal Infection in Neurosurgical Patients
The value of CSF IL-6, IL-8 and Procalcitonin in detecting an early diagnosis of intrathecal infection in neurosurgical patients with an external ventricular drainage is evaluated.
- Trial name
- NCT02875808
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- University Medicine Greifswald
Localized Infection, Sepsis
The Procalcitonin and Survival Study
This is a randomised, single blinded, multicentre trial to evaluate whether daily procalcitonin (PCT) measurements and immediate diagnostic and therapeutic responses to abnormal values and day-to-day changes can reduce the…
- Conditions
- Localized Infection, Sepsis, Multiple Organ Failure
- Trial name
- PASS (NCT00271752)
- Testing
- Earlier therapeutic changes regarding infection
- Where
- 9 sites in Denmark
- Volunteers
- 1,200 people
- Sponsor
- Danish Procalcitonin Study Group
Body Composition Changes, Muscle Mass
Effects of Daily Magnesium Complex Supplementation on Body Composition in University Students
This study will investigate whether daily supplementation with 400 mg of magnesium from a triple magnesium complex containing magnesium glycinate, magnesium malate, and magnesium citrate can improve body composition in young…
- Conditions
- Body Composition Changes, Muscle Mass, Body Fat Percentage
- Trial name
- NCT07906678
- Testing
- Triple Magnesium Complex
- Where
- Bangladesh
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Noakhali Science and Technology University
Porphyria Cutanea Tarda, Hepatitis C
Harvoni Treatment Porphyria Cutanea Tarda
In the medical literature there case reports that Harvoni improves symptoms in patients with PCT. However, this has never been systematically tested.
- Trial name
- NCT03118674
- Testing
- Harvoni
- Where
- 3 sites in United States
- Volunteers
- 23 people
- Sponsor
- Wake Forest University Health Sciences
Diagnostic and Predictive Value
Diagnostic and Prognostic Value of Combination Biomarkers in the Critically Ill Patient With Sepsis.
Sepsis is a common cause for morbidity and mortality in critically ill patients. With the development of medical skills, the mortality is still remain very high.
- Trial name
- NCT01687010
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Jianfeng Xie
Post-operative Complication
The Value of Infectious Biomarkers for Prediction of Complication After Hepatopancreatobiliary Surgery
Post operative complication after hepatopancreatobiliary surgery is high as 30-50%，which is the main reason for patient admitted to ICU.
- Trial name
- NCT02878668
- Testing
- hepatopancreatobiliary surgery
- Where
- 7 sites in China
- Volunteers
- 700 people
- Sponsor
- Shanghai Zhongshan Hospital
PTSD
A Comparison of Cognitive Processing Therapy (CPT) Versus Present Centered Therapy (PCT) for Veterans
The purpose of this study is to compare the effectiveness of Cognitive Processing Therapy (CPT) versus Present Centered Therapy (PCT) for male OEF/OIF Veterans with combat related PTSD.
- Trial name
- NCT00607815
- Testing
- Cognitive Processing Therapy, Present Centered Therapy
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- VA Office of Research and Development
Healthy
Percent Body Fat in Breast Fed Infants
The purpose of this study is to learn about normal body composition (% body fat) during the first six months of life in healthy breast-fed babies.
- Trial name
- PeaPod (NCT00616083)
- Where
- 4 sites in United States, Italy
- Volunteers
- 190 people
- Sponsor
- Arkansas Children's Hospital Research Institute
Immunization
Effect of Infant Immunization on Procalcitonin Levels - A Pilot Study
Fever is a well-known side effect of immunizations. When a febrile infant presents to a healthcare site, such as an emergency room, a large number of tests are usually performed, which may include a procalcitonin (PCT) level.
- Trial name
- NCT04295694
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- CAMC Health System
Infection
Biological Markers for the Diagnosis of Central Nervous System Infective Diseases
Bacterial meningitis is a potentially life-threatening disease that is associated with substantial neurological morbidity and mortality. Accurate diagnosis is essential to improve outcome and prevent antibiotic overuse.
- Trial name
- NCT02278016
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Sepsis
Clinical Evaluation of e- Ab Sensor - Based Real-time Diagnosis of Serum Procalcitonin Level
The purpose of this study is to develop a real-time diagnostic technique with e- Ab sensor for serum PCT level measurement will offer a test with lower cost, and increase the applicability of serum Procalcitonin (PCT) level in…
- Trial name
- NCT01388114
- Testing
- Electrosensing Antibody Probe System (e- Ab sensing)
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Acute Biphenotypic Leukemia, Acute Lymphoblastic Leukemia
CD19-Specific T-cells in Treating Patients With Advanced Lymphoid Malignancies
This phase I clinical trial studies the side effects and best dose of CD19-specific T-cells in treating patients with lymphoid malignancies that have spread to other places in the body and usually cannot be cured or controlled…
- Conditions
- Acute Biphenotypic Leukemia, Acute Lymphoblastic Leukemia, Blasts 5 Percent or More of Bone Marrow Nucleated Cells, CD19 Positive
- Trial name
- NCT02529813
- Testing
- Cyclophosphamide, Fludarabine Phosphate, Laboratory Biomarker Analysis
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- M.D. Anderson Cancer Center
Respiratory Tract Infections
Observation of Initial Procalcitonin and the Clinical Course of Patients With Acute Respiratory Tract Infections
Observation of the initial Procalcitonin values and the clinical course of consecutively included patients with Acute Respiratory Tract Infections at general medical practices in greater Hannover.
- Trial name
- NCT00827060
- Where
- Germany
- Volunteers
- 702 people
- Sponsor
- Hannover Medical School
Colonoscopy
Percentage Visualized Mucosa as a Marker for the Quality of Colonoscopy
Primary hypothesis: The percentage of mucosa visualized during the withdrawal of a colonoscopy with reference to the position in the colon by means of the scope-guide is an appropriate parameter for assessment of the quality of…
- Trial name
- NCT04482452
- Testing
- Colonoscopy
- Where
- Switzerland
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Infection, Bacterial Infection
Procalcitonin Level to Discontinue Antibiotics on ICU Patients With no Obvious Site of Infection
The purpose of this study is to test whether a U.S. Food and Drug Administration (FDA) approved laboratory test (PCT Kryptor) can help doctors make better decisions on the need for antibiotic therapy in ICU patients with…
- Conditions
- Infection, Bacterial Infection, Sepsis
- Trial name
- NCT00407147
- Testing
- Procalcitonin assay - B.R.A.H.M.S PCT sensitive Kryptor
- Where
- 3 sites in United States
- Volunteers
- 11 people
- Sponsor
- Brahms AG