Clinical trials: PD
Crohn's Disease
Drug-Disease Interaction in Crohn's Disease
Objective: To determine the effect of C-reactive protein (CRP) status, and infliximab treatment on the pharmacodynamics and pharmacokinetics of verapamil, a model drug for L-type calcium channel blocking, in Crohn's disease (CD)…
- Trial name
- NCT01261286
- Testing
- verapamil
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alberta
Pharmacokinetics and Pharmacodynamics
Comparison of the Pharmacokinetic (PK) and Pharmacodynamic (PD) Biosimilarity of Insulin Aspart 30 Injections After Single-Dose Subcutaneous Administration to Healthy Volunteers
The present study is designed to compare the pharmacokinetic, pharmacodynamic and safety characteristics of UBLIN 30® (test product) and NovoMix®30 (reference product) in healthy male participants.
- Trial name
- NCT07875803
- Testing
- Insulin Aspart 30 Injection (UBLIN 30®)), Insulin Aspart 30 Injection ( NovoMix®30)
- Where
- China
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Zhuhai United Laboratories Co., Ltd.
Non Small Cell Lung Cancer
Consistency of PD-L1 Detecting Method Between E1L3N and 22C3 Monoclonal Antibodies in NSCLC Patients
Evaluated the correlation between the qualitative test results of Xiamen Aide PD-L1 antibody reagent (immunohistochemistry) and the efficacy of Keytruda single-agent therapy, and the research data is used to support the…
- Trial name
- CONFIDENCE (NCT05129462)
- Where
- China
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Hunan Province Tumor Hospital
Heart Failure
Phase 1, Single Ascending Dose Study to Evaluate the Safety, Tolerability, PK, PD, and Comparative Bioavailability of THRV-1268 in Obese Adult Participants
A research study that involves the use of an investigational drug called THRV-1268. The main purpose is to measure the safety (whether it causes any side effects) and tolerability (if it does cause any side effects, how well your…
- Trial name
- NCT07186946
- Testing
- THRV-1268
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Thryv Therapeutics, Inc.