Clinical trials: PET/CT
Neuroendocrine Tumors
Diagnosis and Staging of Neuroendocrine Tumors (NETs) Utilizing 68Ga-DOTATOC PET/CT Scan
The primary goal of the analysis is to estimate the diagnostic accuracy of Gallium 68 (68Ga) -DOTATOC PET/CT for detecting neuroendocrine tumors (NETs) compared to conventional imaging techniques such as Magnetic Resonance…
- Trial name
- NCT03136328
- Testing
- 68Ga-DOTATOC
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Alzheimer's Disease, Dementia
Brain Study of Patients With Frontal Lobe Dementia and Parkinsonian Disorders
The Cognitive Neuroscience Section of the National Institute of Neurological Disorders and Stroke proposes to continue its cross-sectional and longitudinal studies of cerebral metabolism in frontal lobe dementias and atypical…
- Conditions
- Alzheimer's Disease, Dementia, Down's Syndrome
- Trial name
- NCT00001178
- Where
- United States
- Volunteers
- 597 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Tumor, Cardiovascular Diseases
Application of [68Ga]Ga-NI-FAPI-04 PET/CT Imaging in Fibroblast Activation Protein Related Diseases
The purpose of this study is to conduct clinical research on [68Ga] Ga-NI-FAPI-04 PET/CT imaging and further investigate its diagnostic value in fibroblast activation related diseases.
- Conditions
- Tumor, Cardiovascular Diseases, Pulmonary Fibrosis, Rheumatic Immune Diseases Involving Large Blood Vessels
- Trial name
- NCT07464132
- Testing
- Injection of 68Ga-NI-FAPI
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Atherosclerosis, Inflammatory Activity in Carotid Arteries
Effects of Crestor on Inflammation of Atherosclerotic Plaques
The primary aim of this study is to investigate the effect of 40 mg dose of rosuvastatin on carotid plaque inflammation measured with MRI and PET scanning, to evaluate whether these techniques are promising for future proof of…
- Trial name
- NCT00689416
- Testing
- rosuvastatin
- Where
- Sweden
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Metabolism Disorder
Cold Induced Futile Cycles In White Adipose Tissue
Investigation of futile cycles in white adipose tissue under cold conditions for thermogenesis using two substitutes for glucose metabolism (18F-FDG and 13C-Glucose).
- Trial name
- Metabol (NCT04614116)
- Testing
- External cooling, FDG PET/CT, 13C-Glucose injection
- Where
- Switzerland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Kantonsspital Baden
Abdominal Aortic Aneurysm
Sodium Fluoride Imaging of Abdominal Aortic Aneurysms
The purpose of this study is to determine whether Sodium Fluoride imaging (using Positron Emission Tomography-Computed Tomography - PET-CT) is able to help predict the rate of abdominal aortic aneurysm expansion.
- Trial name
- SoFIA3 (NCT02229006)
- Testing
- 18F-NaF PET-CT
- Where
- United Kingdom
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Rectal Cancer (Stage III)
Diagnostic Accuracy and Prognostic Value of 18F FDG PET-CT in the Follow up of Patients With Colorectal Carcinoma.
The goal of this observational study is to learn about the diagnostic and prognostic value of 18f fdg pet ct in follow up of colorectal cancer patients The main question it aims to answer is: Does pet ct have a role in treatment…
- Trial name
- NCT07536321
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Assiut University
Pancreatitis, Graft, Pancreatic Transplant Post-Transplant Dysfunction Rejection
18F-Fluciclovine PET/CT in the Assessment of Pancreatic Transplants
Hypothesis 1: 18F-Fluciclovine PET/CT can correctly and easily identify the pancreatic allograft and determine its viability Aim 1: Assess whether 18F-Fluciclovine can identify the pancreatic allograft accurately and assess its…
- Trial name
- NCT04852523
- Testing
- 18F-fluciclovine
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of Utah
Diagnostic Imaging, Neoplasms
Radiation Dosimetry, Metabolism, Pharmacokinetics, Safety and Tolerability and PET Imaging With BAY94-9392 in Healthy Volunteers and Patients With Cancer or Inflammation
Visual assessment of diagnostic PET/CT (positron emission tomography/computed tomography) images obtained after a single intravenous injection of BAY94-9392 in patients with cancer or inflammation.
- Trial name
- NCT01103310
- Testing
- BAY94-9392
- Where
- 3 sites in United States, Germany and 1 more
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Lantheus Biosciences Ltd.
Healthy Volunteers - Male and Female
Development of an Improved Method of Measuring Total Body Bone Perfusion Using Total-body PET/CT
Broken bones (fractures) are a common problem in several serious health conditions, such as osteoporosis, kidney failure, and sickle cell disease.
- Trial name
- NCT07860346
- Testing
- 1-hour Total Body PET/CT scan using the tracer [18F]-sodium fluoride
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- King's College London
Cardiac Sarcoidosis
Diagnostic Utility of SGLT1/2 Inhibition to Facilitate Myocardial Glucose Suppression
This is a pilot mechanistic study of the diagnostic utility of sodium-glucose cotransporter-1/2 inhibition (SGLT1/2) on myocardial glucose suppression on FDG PET/CT.
- Trial name
- NCT06510894
- Testing
- Sotagliflozin
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Age-related Hearing Loss, PET-CT
PET-CT-based Study of Central Mechanisms of Cortical Metabolism in 18F-FDG and 18F-AV1451 Age-related Deafness
The participants were recruited from elderly subjects in the age range of 60-85 years and audiological assessments, cognitive function assessments, non-invasive brain imaging, behavioral assessments were collected from the normal…
- Trial name
- NCT05796011
- Testing
- hearing aids, without hearing intervention, healthy control
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Neoplasms
68Ga-N188 PET/CT Imaging in Malignancy
The Nectin-4 protein belongs to the cell adhesion factors family and has a tissue-specific expression spectrum in normal human tissues.
- Trial name
- NCT05593107
- Testing
- [68Ga]N188
- Where
- China
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
PET Images and Deep Neural Networks Algorithms
Positron Emission Tomography (PET) Images Using Deep Neural Networks
PET images are based on detecting two annihilation 511 KeV photons that are produced by positron emitting isotopes. The longer the acquisition time, the more photons are detected and processed, resulting in better image quality.
- Trial name
- NCT04140565
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Acute Aortic Syndrome, Aortic Dissection
18F Sodium Fluoride PET/CT in Acute Aortic Syndrome
The purpose of this study is to determine whether Sodium Fluoride imaging (using Positron Emission Tomography-Computed Tomography - PET-CT) is able to predict disease progression in acute aortic syndrome.
- Conditions
- Acute Aortic Syndrome, Aortic Dissection, Penetrating Aortic Ulcer, Intramural Hematoma
- Trial name
- FAASt (NCT03647566)
- Testing
- 18F Sodium Fluoride Positron Emission Tomography / Computed Tomography, CT Aortic Angiogram, Aortic MRI
- Where
- United Kingdom
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Insulin Resistance, Atherosclerosis
Human Atherosclerotic Plaque Inflammation Imaged Using PDG-PET/CT
People with diabetes are at increased risk for atherosclerosis and have high CVD morbidity and mortality rates. Tools for detecting and quantifying atherosclerotic pro/regression in people with diabetes and other CVD risk factors…
- Conditions
- Insulin Resistance, Atherosclerosis, Cardiovascular Disease, HIV/AIDS
- Trial name
- NCT00958815
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Alzheimer Disease, Mild Cognitive Impairment
Ultralow Dose PET Imaging of 18F-Florbetapir, 18F-Flutemetamol
The goal of this clinical trial is to evaluate an investigational ultralow dose Positron Emission Tomography (PET) imaging technique for Alzheimer's disease, mild cognitive impairment, other forms of dementia detection and…
- Conditions
- Alzheimer Disease, Mild Cognitive Impairment, Dementia, Healthy Volunteers
- Trial name
- NCT07012993
- Testing
- 18F-Florbetapir or 18F-Flutemetamol
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Akiva Mintz
Non-Obstructive Coronary Atherosclerosis
Effect of Mental Stress on Myocardial Perfusion in Women
Mental stress-induced myocardial ischemia(MSIMI) has been recognized a significant clinical problem. Evidence has shown that individuals with MSIMI have 2 to 2.5 times higher risk to develop a major averse cardiovascular events…
- Trial name
- MS in women (NCT03982901)
- Testing
- Mental Stress Test
- Where
- China
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Guangdong Provincial People's Hospital
Breast Cancer
Dual Integrin αvβ3 and GRPR Targeting PET Imaging in Breast Cancer Patients
This is an open-label positron emission tomography/computed tomography (PET/CT) study to investigate the diagnostic performance and evaluation efficacy of 68Ga-NOTA-BBN-RGD in breast cancer patients.
- Trial name
- NCT02749019
- Testing
- 68Ga-NOTA-BBN-RGD
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Menopause, Obesity
Brown Adipose Tissue Activity in Pre- and Postmenopausal Women
The physiological relevance of brown adipose tissue (BAT) in humans is largely unknown. The investigators have shown that suppressing ovarian function in premenopausal women reduces resting energy expenditure (REE), and this is…
- Trial name
- NCT02927392
- Testing
- Leuprolide acetate
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver