Clinical trials: PET / CT
Healthy Volunteer, Coronary Arterial Disease
Ultralow Dose PET Imaging of 18F-flurpiridaz
The goal of this clinical trial is to evaluate an investigational ultralow dose positron emission tomography (PET) imaging technique for known or suspected coronary artery disease (for detecting myocardial ischemia or infarction)…
- Conditions
- Healthy Volunteer, Coronary Arterial Disease, Myocardial Ischemia, Myocardial Infarction
- Trial name
- NCT07284576
- Testing
- 18F-flurpiridaz
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Akiva Mintz
Mild Traumatic Brain Injury
Advanced Imaging Tools in the Study of Mild Traumatic Brain Injury
We will utilize a set of imaging modalities including computed tomography (CT), positron emission tomography (PET), and a suite of magnetic resonance imaging (MRI) tools, to investigate the changes in the human brain resulting…
- Trial name
- mTBI (NCT01044615)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kettering Health Network
PET/CT Imaging, NSCLC
Study on c-Met Targeted PET/CT Imaging in NSCLC
The investigators developed a 18F labeled small molecule, 18F-TSPF, based on c-Met TKI, as a targeted molecular imaging agent for noninvasive and repeatable detecting c-Met activation status.
- Trial name
- NCT06911697
- Testing
- 18F-TSPF PET/CT
- Where
- China
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Xilin Sun
Lung Cancer
68Ga-BNOTA-PRGD2 PET/CT in Healthy Volunteers and Lung Cancer Patients
This is an open-label dynamic whole-body PET/CT (positron emission tomography/computed tomography) study for investigation of radiation dosimetry, plasma pharmacokinetics, biodistribution, safety and diagnostic performance of…
- Trial name
- GRGDLC (NCT01527058)
- Testing
- 68Ga-BNOTA-PRGD2
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Solid Tumor Malignancies, Hematologic Cancer
The Application of 18F-G1 PET/CT Targeting Granzyme B in the Pan-cancer Immunotherapy
The purpose of this study is to explore the effectiveness of 18F-G1 PET/CT in patients with solid tumors and hematological malignancies receiving immunotherapy
- Conditions
- Solid Tumor Malignancies, Hematologic Cancer, Lung Cancer, Esophagus Cancer
- Trial name
- NCT07039474
- Testing
- 18F-G1
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Alzheimer Disease, Healthy Volunteer
Neuroinflammation Imaging in AD
This research study is being done to learn more about inflammation in the brain using Positron Emission Tomography/Computed Tomography (PET/CT) imaging in people with Alzheimer's Disease/Mild Cognitive Impairment or healthy…
- Trial name
- NCT04274998
- Testing
- [18F]NOS, [11C]PBR28
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Diabetic Autonomic Neuropathy, Gastrointestinal Motility Disorder
Gastrointestinal Motility Among Diabetes Patients
Gastrointestinal (GI) symptoms including vomiting, nausea, abdominal pain, constipation or chronic diarrhea affect a large number of patients with diabetes mellitus (DM).
- Conditions
- Diabetic Autonomic Neuropathy, Gastrointestinal Motility Disorder, Diabetes Mellitus, Change of Transit or Circulation
- Trial name
- NCT02573519
- Testing
- 11C Donepezil PET/CT scan, 3D-Transit, 3D-Transit during treatment with Pyridostigmine
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Renal Cell Carcinoma, Clear Cell Renal Cell Carcinoma
68Ga- and 18F-CAIX PET Imaging Study
This exploratory clinical imaging study will evaluate the safety, tolerability, biodistribution, lesion detection, and tumor uptake characteristics of 68Ga- and 18F-labeled carbonic anhydrase IX (CAIX)-targeted positron emission…
- Conditions
- Renal Cell Carcinoma, Clear Cell Renal Cell Carcinoma, Renal Tumor
- Trial name
- CAIX-PET (NCT07875946)
- Testing
- 68Ga-CAIX PET/CT, 18F-CAIX
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Healthy
Study of Radiotracer [18F]Fluortriopride ([18F]FTP) by PET/CT
In this phase 1 pilot study, positron emission tomography (PET/CT) imaging will be used to determine the biodistribution, metabolism and excretion of a novel radiotracer [18F]Fluortriopride ([18F]FTP).
- Trial name
- NCT02379338
- Testing
- [18F]Fluortriopride
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Multiple Myeloma, Multiple Myeloma and Malignant Plasma Cell Neoplasms
68Ga-BCMA PET/CT in Multiple Myeloma
This is a prospective, multicenter diagnostic imaging study designed to evaluate the diagnostic accuracy and clinical utility of BCMA-targeted positron emission tomography/computed tomography (PET/CT) in patients with multiple…
- Conditions
- Multiple Myeloma, Multiple Myeloma and Malignant Plasma Cell Neoplasms, Multiple Myeloma and Plasma Cell Neoplasm
- Trial name
- NCT07319897
- Testing
- 68Ga-BCMA PET/CT
- Where
- 5 sites in China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
PET/CT, COVID-19
Study for Quantitative Analysis of the Recovered COVID-19 Patients by 18F-FDG-PET/CT
In this study, clinically cured patients with severe COVID-19 were used to evaluate the therapeutic effect of COVID-19 and the recovery and health status of patients over time with highly sensitive PET/CT imaging technology.
- Conditions
- PET/CT, COVID-19, Respiratory Function, Inflammatory Lesions
- Trial name
- NCT04519255
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fifth Affiliated Hospital, Sun Yat-Sen University
Healthy
Organ Interaction Patterns in Healthy Individuals for Improved PET/CT Diagnostics
The study titled "Study to determine interaction patterns of different organs in healthy volunteers as a basis for better patient diagnostics using PET/CT imaging" is designed to investigate the interaction patterns of different…
- Trial name
- Healthy-PET (NCT05936411)
- Testing
- Siemens Quadra PET/CT and [18F]FDG, Apple i-Watch
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Prostate Cancer, PET/CT
Head-to-head Comparison of [68Ga]Ga-PSMA-D5 With [68Ga]Ga-PSMA-11 PET/CT in PCa Diagnosis, Recurrence, and Metastasis
To prospectively evaluate the radiodrug biodistribution of a novel PET imaging agent [68Ga]Ga-PSMA-D5 in different organs of prostate cancer patients and its diagnostic efficacy in the diagnosis, recurrence and metastasis of…
- Trial name
- NCT05955677
- Testing
- [68Ga]Ga-PSMA-D5, [68Ga]Ga-PSMA-11
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Anhui Provincial Hospital
PASC Post Acute Sequelae of COVID 19, Long COVID
From Inflammation to Remodelling Towards Personalized Diagnosis in Post-acute Sequelae of COVID-19
Rationale: The diagnosis and pathogenesis of long COVID remains unknown. We have previously shown that [68Ga]FAPI Positron Emission Tomography-Computed Tomography (PET/CT) imaging shows potential for diagnosis and molecular…
- Conditions
- PASC Post Acute Sequelae of COVID 19, Long COVID, Long Covid-19, PASC
- Trial name
- LIBERATE (NCT06911476)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Non-Obstructive Coronary Atherosclerosis
Effect of Mental Stress on Myocardial Perfusion in Women
Mental stress-induced myocardial ischemia(MSIMI) has been recognized a significant clinical problem. Evidence has shown that individuals with MSIMI have 2 to 2.5 times higher risk to develop a major averse cardiovascular events…
- Trial name
- MS in women (NCT03982901)
- Testing
- Mental Stress Test
- Where
- China
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Guangdong Provincial People's Hospital
Parkinson Disease
Ioflupane I123 (DaTSCAN) and Positron Emission Tomography-computed Tomography Fludeoxyglucose (PET-CT FDG) to Assess Brain Function of Parkinson Patients' First Degree Relatives
Parkinson Disease is one of the most common neurodegenerative illnesses. First degree relatives of Parkinson patient are in high risk for developing the disease.
- Trial name
- NCT01089270
- Where
- Israel
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Parkinson Disease
Ioflupane I123 (DaTSCAN) and Positron Emission Tomography-computed Tomography Fludeoxyglucose (PET-CT FDG) to Assess Brain Function of Parkinson Patients With Different Genetic Characteristics
Parkinson disease is one of the most common neurodegenerative illnesses. The disease is characterized by decrease in dopamine levels and decrease in the number of dopaminergic neurons and dopamine receptors.
- Trial name
- NCT01089283
- Where
- Israel
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Brown Adipose Tissue, Cold Exposure
Intermittent Cold Exposure and Brown Adipose Tissue Hyperplasia
This clinical trial explores how repeated short-term cold exposure impacts the molecular and physiological function of brown adipose tissue (BAT), a thermogenic organ associated with improved cardiometabolic health.
- Conditions
- Brown Adipose Tissue, Cold Exposure, 18F-FDG PET/CT
- Trial name
- ICEBATH (NCT07048405)
- Testing
- Cooling, Biopsies, Injection of 18F-FDG
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Parkinson Disease
11C-PIB PET/CT in Patients With Parkinson's Disease and Parkinsonian Dementia Syndromes
To evaluate the potential contribution of amyloid burden, as indexed by 11C-Pittsburgh compound B (PiB) retention, to the progression of cognitive impairments in patients with Parkinson's disease(PD).
- Trial name
- NCT03555292
- Testing
- 11C-PiB
- Where
- 3 sites in China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Oriental Neurosurgery Evidence-Based-Study Team
Pulmonary Disease, Chronic Obstructive
Effects of Liraglutide in Chronic Obstructive Pulmonary Disease
The study is a 44 weeks, prospective, randomized, placebo-controlled, double-blinded, parallel group two-center trial. Forty patients are recruited among the outpatients of the chronic obstructive pulmonary disease (COPD) clinic…
- Trial name
- NCT03466021
- Testing
- Liraglutide
- Where
- 2 sites in Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Claus Bogh Juhl