Clinical trials: PET CT
Diffuse Large B-Cell Lymphoma
MRD-Adapted Low-Dose Radiation Therapy During Frontline Chemoimmunotherapy for Diffuse Large B-Cell Lymphoma
This prospective feasibility study evaluates a minimal residual disease (MRD)-adapted treatment strategy in patients with diffuse large B-cell lymphoma (DLBCL) receiving frontline chemoimmunotherapy.
- Trial name
- NCT07517705
- Testing
- Low-Dose Radiation Therapy (LDRT), Standard Frontline Chemoimmunotherapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Nebraska
Peritoneal Cancer, Peritoneal Metastases
The PIPAC-OPC7 Study: The Use of PET/CT Scans as a Method of Evaluation in Patients Treated With PIPAC, a Pilot Study.
The pilot study will investigate the use of repeated FDG-PET/CT scans in 16 patients with peritoneal metastasis originating from abdominal cancers treated with Pressurized Intraperitoneal Aerosol Chemotherapy.
- Conditions
- Peritoneal Cancer, Peritoneal Metastases, Peritoneal Carcinomatosis, Abdominal Cancer
- Trial name
- NCT06144853
- Testing
- scan
- Where
- Denmark
- Volunteers
- 34 people
- Sponsor
- Odense University Hospital
PET-CT, Lymphoma
PET-CT in Lymphoma Among the Eldery
This study investigates PET-CT imaging patterns and metabolic parameters in elderly patients (≥60 years) diagnosed with lymphoma, aiming to enhance diagnostic accuracy and prognosis using 18F-FDG PET/CT scans.
- Conditions
- PET-CT, Lymphoma, Elderly, Metabolic Parameters
- Trial name
- NCT07259941
- Volunteers
- 63 people
- Sponsor
- Assiut University
Prostate Cancer
Metabolic Change in Prostate Cancer Bone Metastases on 68Ga-HBED-CC-PSMA PET/CT Following Radium-223 Therapy
Broadly, the objective of this study is to evaluate the fractional decline of intensity of tracer uptake measured by SUVmax on 68Ga-PSMA PET/CT in bone metastases from prostate cancer following treatment with radium-223 as a…
- Trial name
- NCT03062254
- Testing
- radium-223 dichloride
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- Sir Mortimer B. Davis - Jewish General Hospital
Thyroid Cancer
The Value of 68Ga-FAPI PET/CT in Preoperative Evaluation of Thyroid Cancer with Lymph Node Metastases
This study aims to investigate the value of 68Ga-FAPI in the preoperative evaluation of thyroid cancer of different pathologic types.
- Trial name
- NCT06730529
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Ruijin Hospital
Thyroid Pathology, Head and Neck Cancer (H&N)
FAPI PET Imaging - An Exploratory Study
This study is testing a new imaging tracer called [18F]FAPI-74 with PET scans. Researchers want to find out how well this tracer shows certain diseases in the body, including several types of cancer and some non-cancer conditions…
- Conditions
- Thyroid Pathology, Head and Neck Cancer (H&N), Sinonasal Tract Tumor, Sarcoidosis
- Trial name
- FAPIPET (NCT07705074)
- Testing
- [18F]FAPI-74 PET/CT
- Where
- 5 sites in Switzerland
- Volunteers
- 770 people
- Sponsor
- Martin Huellner
Aortic Valve Stenosis, Coronary Artery Disease
Correlation of FFR and iFR With Cardiac PET Perfusion in Patients With Severe Aortic Valve Stenosis
Aortic valve stenosis (AS) affects 2-7% of persons > 65 years, symptoms include: angina and dyspnea, dizziness and syncope. Coincidence of coronary artery disease (CAD), also presenting with angina and dyspnea, in patients with…
- Trial name
- TAVI PET (NCT04882488)
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Heart and Diabetes Center North-Rhine Westfalia
Crohn Disease
18F-FDG and 68Ga-FAPI PET/CT in Crohn's Disease
Intestinal stricture is a complication of Crohn's disease (CD), which is thought to be the result of chronic transmural inflammation combined with a dysregulated wound-healing process.
- Trial name
- NCT04502303
- Testing
- 18F-FDG and 68Ga-FAPI PET/CT
- Volunteers
- 30 people
- Sponsor
- Peking Union Medical College Hospital
Diabetes Mellitus, Type 2, PreDiabetes
18F-FDOPA PET/CT Imaging in Patients Undergoing Metabolic Surgery
The aim of the study is to compare the endocrine function of pancreas between pre and post metabolic surgery in patients with type 2 diabetes or prediabetes.
- Conditions
- Diabetes Mellitus, Type 2, PreDiabetes, Obesity
- Trial name
- NCT03821961
- Testing
- Metabolic Surgery
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Korea University Anam Hospital
Giant Cell Arteritis, Polymyalgia Rheumatica
Assessing Biomarker in Giant Cell Arteritis and Polymyalgia Rheumatic
The GCAIO study is an innovative, multimodal research initiative designed to enhance the understanding, diagnosis, and management of giant cell arteritis (GCA) and frequently associated polymyalgia rheumatica (PMR).
- Trial name
- GCAIO (NCT06460142)
- Testing
- Aortic/ cardiac magnetic resonance imaging, Vascular ultrasound, Transorbital Ultrasound
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Bonn
Epithelial Ovarian Cancer
[18F]Fluoro-PEG-folate PET/CT Imaging in Epithelial Ovarian Cancer
The pre-operative assessment of intra-abdominal tumor load in patients with epithelial ovarian cancer (EOC) remains unreliable with standard imaging modalities.
- Trial name
- NCT05215496
- Testing
- [18F]fluoro-PEG-folate PET/CT scan
- Where
- Netherlands
- Volunteers
- 5 people
- Sponsor
- Lioe-Fee de Geus-Oei, MD PhD
Non-Small Cell Lung Cancer
A Study of Changes in FDG- and FLT-PET Imaging in Patients With Non-Small Cell Lung Cancer Following Treatment With Erlotinib
This is a single-arm, open-label, multicenter, international pilot study to evaluate changes that occur in 2-deoxy-2-[18F]fluoro-D-glucose (FDG)- and 3'-deoxy-3'-[18F]fluorothymidine(FLT)-PET (Positron Emission Tomography)…
- Trial name
- NCT00453362
- Testing
- 2-deoxy-2-[18F]fluoro-D-glucose (FDG), 3'-deoxy-3'-[18F]fluorothymidine (FLT), erlotinib HCl
- Volunteers
- 88 people
- Sponsor
- Genentech, Inc.
Head and Neck Cancer, Lung Cancer
[18F]HX4 PET/CT Imaging for Detection of Hypoxia
The aim of this study is to investigate the radiotracer [18F]HX4 for non-invasive detection of hypoxia in patients with head and neck, or lung cancer.
- Trial name
- OXYPET (NCT02976883)
- Testing
- [18F]HX4 diagnostic PET/CT scan
- Where
- United Kingdom
- Volunteers
- 8 people
- Sponsor
- Nottingham University Hospitals NHS Trust
Lung Cancer, Non Small Cell Lung Cancer
Benefits Study of Respiratory-gated PET Acquisition in Lung Disease
Fluorodeoxyglucose (FDG) positron emission tomography (PET) is now widely used for cancer imaging purpose, notably for preoperative work-up. It aims at visualizing organs metabolism.
- Conditions
- Lung Cancer, Non Small Cell Lung Cancer, Chronic Obstructive Pulmonary Disease
- Trial name
- PneumoTEP (NCT01812031)
- Testing
- medical imaging
- Where
- France
- Volunteers
- 103 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Neuroendocrine Tumors, Von Hippel-Lindau Syndrome
Evaluation of 68Gallium-DOTATATE PET/CT for Detecting Neuroendocrine Tumors
Background: Neuroendocrine tumors (NETs) are rare but have been more common over the past decade. The only treatment for NETs is surgery, but most are found when they are too advanced for surgery.
- Conditions
- Neuroendocrine Tumors, Von Hippel-Lindau Syndrome, Hippel-Lindau Disease
- Trial name
- NCT01967537
- Testing
- 68Gallium DOTATATE, Radio-guided surgery
- Where
- United States
- Volunteers
- 341 people
- Sponsor
- National Cancer Institute (NCI)
Tumor, Solid
18F-AlF-FAPi-04 PET/CT Imaging in Patients With Solid Tumor
To evaluate the potential usefulness of 18F-AlF-FAPi-04 PET/CT for the diagnosis of primary and metastatic lesions in solid cancer.
- Trial name
- NCT06126705
- Testing
- Radiation: 18F-AlF-FAPi-04, Radiation: 18F-FDG
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Affiliated Hospital of North Sichuan Medical College
Neuroendocrine Carcinoma Metastatic, Pancreatic Tumors
FTT PET/CT in Pancreatic Neuroendocrine Tumors
A pilot study to evaluate the expression of PARP-1 in patients with pancreatic neuroendocrine tumors will be conducted. This will be done via the use of a novel PET imaging agent, [18F]FluorThanatrace ([18F]FTT).
- Trial name
- NCT07114939
- Testing
- [18F]FluorThanatrace
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Neuroendocrine Tumors
PET/CT Imaging of uPAR-expression in Patients With Neuroendocrine Tumors Using 68Ga-NOTA-AE105
The aim of this non-randomised, prospective study is to investigate the applicability and prognostic value of uPAR PET/CT with the radioligand 68Ga-NOTA-AE105 in patients with neuroendocrine tumors (NETs).
- Trial name
- NCT03278275
- Testing
- One injection of 68Ga-NOTA-AE105, PET/CT
- Where
- Denmark
- Volunteers
- 116 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Cancer of Head and Neck
Forecasts Impact of the Pre-therapeutic TEP-TDM in the 18-FDG Restaging of Upper Aero-digestive Tract Cancers
Head and neck (HN) cancer is the sixth most common malignancy worldwide, with around 800 000 new cases and 320 000 deaths in 2015.
- Trial name
- RENOVATE (NCT03841175)
- Where
- France
- Volunteers
- 477 people
- Sponsor
- University Hospital, Brest
Triple Negative Breast Cancer
68Ga-FAPI-46 PET/CT for Predicting Histological Response in Triple-negative Breast Cancer (FAP-IT)
Prospective multicenter study evaluating the prediction of histological response after neoadjuvant pembrolizumab in combination with chemotherapy by pre-treatment 68Ga-FAPI-46 PET/CT imaging in patients with early-stage high-risk…
- Trial name
- FAP-IT (NCT06349512)
- Testing
- 68Ga-FAPI-46 PET/CT imaging
- Where
- 6 sites in France
- Volunteers
- 60 people
- Sponsor
- Institut Curie