Clinical trials: PET-CT
Alzheimer's Disease, Early Onset, Logopenic Progressive Aphasia
Tau Imaging in Young Onset Dementia
The central goal of this study is to determine and compare the similarities and differences in regional brain uptake of [18F]T807 in patients with typical Alzheimer's Disease (AD), Posterior Cortical Atrophy (PCA), and Logopenic…
- Conditions
- Alzheimer's Disease, Early Onset, Logopenic Progressive Aphasia, Posterior Cortical Atrophy (PCA)
- Trial name
- NCT02289118
- Testing
- [18F]-T807 imaging tracer
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Pennsylvania
Metastatic Prostate Cancer
Expanded Access to Diagnostic Imaging for Staging of Recurrent Prostate Cancer
This Phase 3 study will target approximately 100 men over age 18 who have a biochemical relapse or other evidence of relapse of prostate cancer after primary treatment. The purpose of this study is to: A.
- Trial name
- NCT02260817
- Testing
- 11C-choline Injection
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- Global Isotopes, LLC d/b/a Zevacor Molecular
Siewert Type I-II Adenocarcinoma of the Esophagus
Siewert Type I-II: CT, PET-CT, EUS Sensitivity/Specificity for the Assessment of Lymph Node Metastases
In Siewert type I/II EAC, sensitivity/specificity of CT, PET-CT, EUS for assessment of N descriptor in defined groups of lymph nodes were investigated.
- Trial name
- ADECC2-2017 (NCT03529968)
- Testing
- esophagectomy
- Where
- Italy
- Volunteers
- 101 people
- Sponsor
- University of Bologna
Prostate Cancer, BRCA Mutation
The GENPET Study - An Imaging Study of FCH-PET-CT in Men With Prostate Cancer and a DNA Repair Gene Mutation.
The aim of the study is to determine if PET-CT imaging (using contrast recommended in clinical guidelines) is superior to combined bone scan and MRI/CT of the abdomen \& pelvis in detecting the increased incidence of metastasis…
- Conditions
- Prostate Cancer, BRCA Mutation, Mismatch Repair Gene Mutation, ATM Gene Mutation
- Trial name
- GENPET (NCT05097274)
- Testing
- MRI pelvis or CT imaging under clinical management for Pr Ca, Whole body bone scan imaging, PET-CT imaging
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Institute of Cancer Research, United Kingdom
Brain Metastases
Feasibility of 18F-Fluciclovine PET/CT to Identify Brain Metastasis
The goal of this diagnostic intervention clinical trial is to compare 18F-Fluciclovine uptake within brain lesions over 60 minutes compared with standard of care positive histology confirmation or confirmation MRI images.
- Trial name
- NCT06055790
- Testing
- 18F-Fluciclovine (Axumin) PET/CT
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Arizona
Breast Cancer
Molecular Imaging of Breast Cancer With Breast PET/CT
This study is a feasibility study to determine if a combined breast PET/CT scanner can image malignant functional activity while determining anatomical structure in the same clinical setting for patients with breast cancer.
- Trial name
- NCT00584753
- Testing
- Positron emission tomography and computed tomography
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Tumor, Brain
Multi-parametric MRI/Fluorine-18 Fluciclovine PET-CT in Glioblastoma
Glioblastoma is the most common adult brain tumour with approximately 2000 new cases each year in the UK. Optimal treatment consists of surgery followed by radiotherapy and chemotherapy but despite this survival is poor with only…
- Trial name
- NCT03409549
- Testing
- Fluciclovine PET/CT
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
Primary Aldosteronism Concurrent With Autonomous Cortisol Secretion
Accuracy of 68Ga-Pentixafor PET/CT for Subtypting Diagnosis in Patients With Primary Aldosteronism Concurrent With Autonomous Cortisol Secretion
To evaluate the accuracy of 68Ga-Pentixafor PET-CT in the classification diagnosis of primary aldosteronism concurrent with autonomous cortisol secretion patient, using AVS and/or postoperative remission as the reference standard…
- Trial name
- ABOARD (NCT06635993)
- Testing
- 68Ga-Pentixafor PET/CT
- Where
- China
- Volunteers
- 97 people
- Sponsor
- Qifu Li
Breast Carcinoma, Fallopian Tube Carcinoma
Serial Imaging of the Novel Radiotracer [^18F] FLuorthanatrace ([^18F] FTT) by PET/CTF
This phase I trial studies how well fluorine F 18 fluorthanatrace positron emission tomography (PET)/computed tomography (CT) works in patients with solid tumors.
- Conditions
- Breast Carcinoma, Fallopian Tube Carcinoma, Ovarian Carcinoma, Primary Peritoneal Carcinoma
- Trial name
- NCT03604315
- Testing
- Computed Tomography, Fludeoxyglucose F-18, Fluorine F 18 Fluorthanatrace
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- M.D. Anderson Cancer Center
Prostate Carcinoma
RefleXion PET/CT Imaging Performance in Patients With Prostate Cancer
This clinical trial examines RefleXion Medical Radiotherapy System (RMRS) imaging to the standard of care (SOC) [18F]-DCFPyL positron emission tomography-computed tomography (PET-CT) imaging in patients with prostate cancer.
- Trial name
- NCT05470699
- Testing
- Computed Tomography, Fluorine F 18 Piflufolastat, Positron Emission Tomography
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- City of Hope Medical Center
Advanced Head and Neck Carcinoma, Advanced Non-small Cell Lung Carcinoma
PET/CT Imaging of Angiogenesis in Lung or Head and Neck Cancers Prior or During Chemotherapy With Antiangiogenic Agents
The primary objective of this Phase II study is to evaluate the use of labelled RGD ligand in PET/CT to predict and/or to early assess the efficacy of chemotherapy including an agent with antiangiogenic effect.
- Trial name
- MLAPOCHI (NCT02325349)
- Testing
- radiopharmaceutical (Flotegatide (18F) or RGD (68Ga)
- Where
- France
- Volunteers
- 1 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Endometriosis
Imaging of Endometriosis With Total-body PET-CT (PET-Endo)
Endometriosis is a disease that affects 1 in 10 women and is associated with debilitating pain and infertility. Endometriosis is where cells similar to those lining the womb (the 'endometrium') grow elsewhere in the body, forming…
- Trial name
- PET-Endo (NCT07523997)
- Testing
- PET/CT, PET/MRI, Buscopan 20 MG/ML Injectable Solution
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Edinburgh
NSCLC
Pathological and Nuclear Medicine Factors for Prognosis in Lung Carcinoma
Retrospective study in patients with therapy-naive non small cell lung carcinoma correlating presurgical F18-FDG-PET/CT imaging texture analysis data with postsurgical molecular pathology data and clinical patient outcome.
- Trial name
- PANU (NCT04276025)
- Testing
- Clinical routine F18-FDG-PET/CT, molecular pathology and clinical outcome
- Volunteers
- 2,000 people
- Sponsor
- Klinikum Bayreuth GmbH
Fibrosis (Morphologic Abnormality)
FAPI-74 PET/CT in Adults With Fibrosis
This protocol is intended as a basket protocol designed to evaluate the use of Fibroblast Activating Protein (FAP) PET/CT in imaging the presence of fibrosis caused by a variety of medical conditions where fibrosis is believed to…
- Trial name
- NCT06413355
- Testing
- [F-18]-FAPI-74
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Small Cell Lung Cancer
CXCR4 PET/CT for Predicting Outcome in Limited-Stage Small Cell Lung Cancer
This prospective observational study aims to evaluate the clinical value of CXCR4-targeted PET/CT imaging in patients with limited-stage small cell lung cancer (LS-SCLC).
- Trial name
- NCT07316309
- Where
- China
- Volunteers
- 33 people
- Sponsor
- Shandong Cancer Hospital and Institute
Skeletal Scintigraphy, FDG PET/CT
Radiation Exposure Awareness From Patients Undergoing Nuclear Medicine Diagnostic Scans
This questionnaire is aimed at finding out if patients understand how much radiation they are being exposed to when they have a bone scan (99mTc-MDP)or an FDG PET/CT scan (18F-FDG PET/CT).
- Trial name
- REA (NCT03458585)
- Testing
- Self-administered questionnaire
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Royal Marsden NHS Foundation Trust
COVID-19, FDG PET/CT
Assessment of Lung Inflammation With FDG PET/CT in COVID-19
The aim of the study was to assess the inflammatory status at the presumed peak of the inflammatory phase in non-critically ill patients requiring admission for COVID-19.
- Conditions
- COVID-19, FDG PET/CT, Inflammation
- Trial name
- NCT04441489
- Where
- Monaco
- Volunteers
- 13 people
- Sponsor
- Centre Hospitalier Princesse Grace
Lymphoma
Optimization of 18F-FDG PET/CT Response Assessment and Prognostic Evaluation Strategies for High-Metabolism Lymphoma
To develop a novel method for evaluating treatment response in lymphoma by utilizing PET/CT imaging data from patients with high-metabolic lymphoma.
- Trial name
- NCT06795113
- Where
- China
- Volunteers
- 4,000 people
- Sponsor
- Ruijin Hospital
Prostate Adenocarcinoma, PSA Failure
68Ga-PSMA PET/CT in Detecting Prostate Cancer Recurrence in Patients With Elevated PSA After Initial Treatment
The purpose of this research study is to see if recurrent prostate cancer can be identified using a special procedure called a positron emission tomography (PET) scan.
- Conditions
- Prostate Adenocarcinoma, PSA Failure, Recurrent Prostate Carcinoma
- Trial name
- NCT02673151
- Testing
- Computed Tomography (CT) scan, 68Ga-PSMA-11, Positron Emission Tomography (PET)
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Andrei Iagaru
Bone Metastases
Validation of Whole Body PET/CT Foundation Model
Prospective multicenter study to validate the diagnostic performance of whole body PET/CT foundation model for bone lesion detection
- Trial name
- NCT07196995
- Volunteers
- 180 people
- Sponsor
- Shanghai 6th People's Hospital
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