Clinical trials: PET-CT
Brown Adipose Tissue, Cold Exposure
Intermittent Cold Exposure and Brown Adipose Tissue Hyperplasia
This clinical trial explores how repeated short-term cold exposure impacts the molecular and physiological function of brown adipose tissue (BAT), a thermogenic organ associated with improved cardiometabolic health.
- Conditions
- Brown Adipose Tissue, Cold Exposure, 18F-FDG PET/CT
- Trial name
- ICEBATH (NCT07048405)
- Testing
- Cooling, Biopsies, Injection of 18F-FDG
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Atherosclerosis
A Study to Evaluate the Effects of 3 Months Dosing With GW856553, as Assessed FDG-PET/CT Imaging
This study is being conducted to assess the potential anti-inflammatory effects of a 3-month treatment with GW856553, on the inflammatory activity within the aorta and carotid plaques, as assessed by FDG-PET/CT.
- Trial name
- NCT00633022
- Testing
- LOSMAPIMOD 7.5 MG
- Where
- 4 sites in United Kingdom
- Volunteers
- 99 people
- Sponsor
- GlaxoSmithKline
HCC - Hepatocellular Carcinoma
[68Ga]Ga-PSMA PET/CT in Hepatocellular Carcinoma: Impact of Multiparametric Dynamic Whole-body Imaging and Kinetic Modeling.
The purpose of this study is to evaluate the use of multiparametric dynamic whole-body [68Ga]Ga-PSMA PET/CT imaging in newly diagnosed HCC patients or in HCC patients with recent suspicion of refractory, residual, or recurrent…
- Trial name
- HIMIKO (NCT06999837)
- Testing
- [68Ga]Ga-PSMA-11
- Where
- 2 sites in France
- Volunteers
- 40 people
- Sponsor
- Nantes University Hospital
Parkinson Disease
Ioflupane I123 (DaTSCAN) and Positron Emission Tomography-computed Tomography Fludeoxyglucose (PET-CT FDG) to Assess Brain Function of Parkinson Patients' First Degree Relatives
Parkinson Disease is one of the most common neurodegenerative illnesses. First degree relatives of Parkinson patient are in high risk for developing the disease.
- Trial name
- NCT01089270
- Where
- Israel
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Multiple Myeloma, Bone Metastases
Evaluation of Whole Body Examination by MRI Integrating the "Zero Time Eco" Sequence (ZTE, Pseudo-CT) for the Detection of Bone Lesions in Multiple Myeloma: Comparison With Pet / CT and Whole Body Scanner
To assess the added value of magnetic resonance imaging (MRI) of the skeleton compared to other validated techniques for the detection of bone lesions in patients with multiple myeloma.
- Trial name
- MM-ZTE (NCT05381077)
- Testing
- MRI
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Head and Neck Cancer, Lung Cancer
[18F]HX4 PET/CT Imaging for Detection of Hypoxia
The aim of this study is to investigate the radiotracer [18F]HX4 for non-invasive detection of hypoxia in patients with head and neck, or lung cancer.
- Trial name
- OXYPET (NCT02976883)
- Testing
- [18F]HX4 diagnostic PET/CT scan
- Where
- United Kingdom
- Volunteers
- 8 people
- Sponsor
- Nottingham University Hospitals NHS Trust
Gastric Cancer
Preliminary Study on the Diagnostic Value Comparison of 18F-FAPI-04 PET/CT and PET/MR in Gastric Cancer
This project aims to comprehensively analyze the diagnostic efficacy of SUVmax, SUVean, TLG, MTV, etc. in gastric cancer through 18F-FAPI-04 PET/CT imaging combined with serum tumor markers and other methods, and construct a…
- Trial name
- NCT06543108
- Testing
- The clinical value of 18F-FAPI-04 PET/CT and PET/MR imaging in the diagnosis and staging of gastric cancer
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Hunan Cancer Hospital
ccRCC, Complex Renal Cyst
68Ga-NYM096 PET/ CT for the Detection of ccRCC in Presurgical Patients With Complex Cystic Renal Leision
This is a prospective, single-center, single-arm, diagnostic phase 2 study aimed at evaluating the sensitivity and specificity of 68Ga-NYM096 PET/CT in detecting clear cell renal cell carcinoma (ccRCC) in patients with complex…
- Trial name
- NYCRCCL (NCT06949215)
- Testing
- 68Ga-NYM096 PET/CT
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Peking Union Medical College Hospital
Malignant Tumors
Clinical Study of Pretreatment PET/CT Parameters for Predicting the Efficacy of 125I Seed Implantation in the Treatment of Malignant Tumors
This study aimed to determine if pre-treatment 18F-FDG PET/CT metabolic parameters could predict the effectiveness of 125I seed implantation for malignant tumors.
- Trial name
- NCT07208487
- Where
- China
- Volunteers
- 41 people
- Sponsor
- Jiangxi Provincial Cancer Hospital
Clear Cell Renal Cell Carcinoma, Suspected Recurrent Renal Clear Cell Carcinoma
Evaluation of 89Zr-TLX250 PET/CT in Chinese Patients With Indeterminate Renal Masses or Suspected Recurrent Renal Clear Cell Carcinoma
The study is designed to evaluate the safety, tolerability, radiation dosimetry and pharmacokinetics 89Zr-TLX250 (also known as 89Zr-DFO-girentuximab) Positron Emission Tomography/Computed Tomography (PET/CT) in adult Chinese…
- Conditions
- Clear Cell Renal Cell Carcinoma, Suspected Recurrent Renal Clear Cell Carcinoma, Recurrent Renal Cell Cancer
- Trial name
- ZIRDOSE-CP (NCT05861778)
- Testing
- 89Zr-Girentuximab
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Telix Pharmaceuticals (Innovations) Pty Limited
SSTR Positive Tumors
Application of Al18F-octreotide PET/CT in Tumors With Positive SSTR Expression
This is an open-label whole-body PET/CT study for investigating the value of Al18F-octreotide PET/CT in patients with SSTR positive tumors
- Trial name
- NCT05749289
- Testing
- Al18F-octreotide
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Colorectal Cancer
PET and CT Scans in Patients With Locally Advanced Primary Rectal Cancer That Can Be Removed During Surgery
RATIONALE: Diagnostic procedures, such as PET and CT scans, may improve the ability to detect the extent of locally advanced primary rectal cancer and may also help to measure a patient's response to treatment.
- Trial name
- NCT00004891
- Testing
- chemotherapy, computed tomography, conventional surgery
- Where
- United States
- Volunteers
- 149 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Lumbar Disc Herniation, Radiculopathy Lumbar
Quantitative Sensory Testing and PET/CT Scanning in Assessment of Surgical Outcome for Lumbar Disc Herniation
Patients with lumbar disc herniation suffer from pain and morbidity. Surgical intervention can be a quick and effective relief, however some individuals experience less favorable outcome.
- Trial name
- PET-Pain (NCT03894943)
- Testing
- PET/CT scan, Quantitative Sensory Testing
- Volunteers
- 61 people
- Sponsor
- Spine Centre of Southern Denmark
Knee Injury
F18-Flouride PET/CT in Acute Knee Injury
18F-fluoride is a positron-emitting bone-seeking agent with favorable pharmacokinetic properties. Its uptake mechanism resembles that of 99mTc-MDP.
- Trial name
- NCT00687921
- Volunteers
- 50 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Pulmonary Disease, Chronic Obstructive
Effects of Liraglutide in Chronic Obstructive Pulmonary Disease
The study is a 44 weeks, prospective, randomized, placebo-controlled, double-blinded, parallel group two-center trial. Forty patients are recruited among the outpatients of the chronic obstructive pulmonary disease (COPD) clinic…
- Trial name
- NCT03466021
- Testing
- Liraglutide
- Where
- 2 sites in Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Claus Bogh Juhl
Thyroid Cancer
Comparison of I-124 PET/CT for the Diagnosis of Thyroid Cancer
Persons diagnosed with thyroid cancer are often treated initially with a thyroidectomy, which is followed by ablation using Iodine-131, a therapy which has been shown to be effective and safe.
- Trial name
- NCT06961084
- Testing
- Iodine-124, Positron Emission Tomography (PET)/Computerized tomography (CT)
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Thomas Hope
Thyroid Nodule, Thyroid Neoplasms
FDG-PET/CT in Evaluation of Cytological Indeterminate Thyroid Nodules to Prevent Unnecessary Surgery (EfFECTS)
The purpose of this study is to determine whether the use of molecular imaging using FDG-PET/CT could prevent unnecessary diagnostic thyroid surgery in case of indeterminate cytology during fine-needle aspiration biopsy.
- Trial name
- EfFECTS (NCT02208544)
- Testing
- Diagnostic Thyroid Surgery, Ultrasound of the head and neck, FDG-PET/CT
- Where
- 15 sites in Netherlands
- Volunteers
- 132 people
- Sponsor
- Radboud University Medical Center
Non-small Cell Lung Cancer, Spread Through Air Space
Deep Learning Signature for Predicting Aggressive Histological Pattern in Resected Non-small Cell Lung Cancer
The purpose of this study is to evaluate the performance of a PET/ CT-based deep learning signature for predicting aggressive histological pattern in resected non-small cell lung cancer based on a multicenter prospective cohort.
- Conditions
- Non-small Cell Lung Cancer, Spread Through Air Space, Visceral Pleural Invasion, Lymphovascular Invasion
- Trial name
- NCT05925738
- Testing
- PET/CT-based Deep Learning Signature
- Where
- 3 sites in China
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Shanghai Pulmonary Hospital, Shanghai, China
Ovarian Cancer, Image
Satisfactory Debulking Prediction Model for Advanced Ovarian Cancer Based on PET-CT Image Data
This project intends to conduct a multicenter retrospective study to evaluate the satisfactory reduction of advanced ovarian cancer using PET-CT images, and explore the correlation between molecular biological characteristics and…
- Conditions
- Ovarian Cancer, Image, Predation
- Trial name
- NCT06533709
- Testing
- Radio-score
- Where
- China
- Volunteers
- 146 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Lymphoma, Extranodal NK-T-Cell
18F-FDG PET/CT-based Prognostic Model for Predicting Outcome in Patients With Natural Killer/T-cell Lymphoma
The purpose of this study is to evaluate whether 18F-FDG PET/CT-based prognostic model of NK/T-cell lymphoma can predict disease progression
- Trial name
- NCT03051555
- Testing
- 18F-FDG PET/ CT
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking University Cancer Hospital & Institute
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