Clinical trials: PPCI
Obstructive Sleep Apnea, ST Elevation Myocardial Infarction
CPAP for OSA on Myocardial Salvage After pPCI for STEMI Patients
The aim of this randomized controlled trial to investigate the effects of CPAP treatment on myocardial salvage index and clinical outcomes at 3 months in patients with OSA and ST-Segment Elevation Myocardial Infarction (STEMI)…
- Trial name
- NCT03444857
- Testing
- Continuous positive airway pressure
- Where
- 2 sites in China
- Volunteers
- 120 people
- Sponsor
- Beijing Anzhen Hospital
STEMI
Comparison Between Two Revascularization Strategies in MVD Patients With Uncomplicated ST-elevation MI
The study aimed to compare major adverse cardiac and cerebrovascular events(MACCE) and mortality at one year between two strategies: complete revascularization including non-culprit lesions percutaneous coronary intervention(PCI)…
- Trial name
- Promise (NCT04582175)
- Testing
- angioplasty
- Where
- Romania
- Volunteers
- 100 people
- Sponsor
- University of Oradea
ST-segment Elevation Myocardial Infarction
Sonothrombolysis in Patients With STEMI
This study evaluates what effect sonothrombolysis may have on spontaneous reperfusion, microvascular obstruction, left ventricular function and infarct size in patients presenting with their first ST-segment Elevation Myocardial…
- Trial name
- NCT03092089
- Testing
- Definity, (Lipid Microspheres) Intravenous Suspension, Myocardial Contrast Echocardiography, Repurfusion therapy with PPCI
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Harald Becher
ST Elevation (STEMI) Myocardial Infarction
LA Strain in Predicting Early Complication in STEMI After PPCI
The goal of this observational study To evaluate the predictive value of left atrial strain for in-hospital outcomes in patients with ST-segment elevation myocardial infarction undergoing PPCI.
- Trial name
- NCT07263282
- Testing
- 2D echocardiography
- Where
- Egypt
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Assiut University
ST-segment Elevation Myocardial Infarction
EROSION II: OCT Guided PPCI in STEMI
This protocol describes a prospective, multi-center study intended to test the hypothesis that patients with STEMI caused by plaque rupture or plaque erosion without obstructive stenosis (diameter stenosis <70%) can be stabilized…
- Trial name
- NCT03062826
- Testing
- dual antiplatelet therapy (aspirin + ticagrelor or aspirin + clopidogrel)
- Where
- 16 sites in China
- Volunteers
- 347 people
- Sponsor
- Harbin Medical University
ST Elevation Myocardial Infarction
Early Discharge After Primary Percutaneous Coronary Intervention
When Primary percutaneous coronary intervention (PPCI) is performed expeditiously and at a high-volume centre, it is the optimal approach for ST elevation myocardial infarction (STEMI) .
- Trial name
- EDAPPCI (NCT01860079)
- Testing
- early discharge
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 900 people
- Sponsor
- Acibadem University
STEMI, Myocardial Reperfusion Injury
Effect of Remote Ischaemic Conditioning on Clinical Outcomes in STEMI Patients Undergoing PPCI (CONDI2/ERIC-PPCI)
The purpose of this study is to determine whether remote ischemic conditioning can reduce cardiac death and hospitalization for heart failure at 12 months in patients presenting with a ST-elevation myocardial infarction and…
- Trial name
- NCT02342522
- Testing
- Remote ischemic conditioning, Control
- Where
- 35 sites in Denmark, Serbia and 2 more
- Volunteers
- 5,413 people
- Sponsor
- University College, London
Ticagrelor
De-escalation of Ticagrelor in Post PPCI
Primary objective: to evaluate the efficacy and safety of De-escalation to lower dose Ticagrelor (60 mg BID) plus Aspirin (75 mg OD) versus continuation of standard dose Ticagrelor (90 mg BID) plus Aspirin (75 mg OD), 1 month…
- Trial name
- NCT05831462
- Testing
- Ticagrelor 60mg
- Volunteers
- 400 people
- Sponsor
- Assiut University
ST Elevation Myocardial Infarction (STEMI)
IMPROVE-STEMI: pPCI Plus Low-dose r-SK in STEMI
This is a multicenter, prospective, pragmatic, randomized controlled trial (IMPROVE-STEMI) aiming to evaluate the efficacy and safety of intracoronary low-dose recombinant streptokinase combined with primary percutaneous coronary…
- Trial name
- IMPROVE-STEMI (NCT07875179)
- Testing
- Recombinant Streptokinase
- Where
- China
- Volunteers
- 3,300 people, healthy volunteers welcome
- Sponsor
- The Affiliated Hospital of Xuzhou Medical University
Left Ventricle Remodeling
Long Term Follow Up and Outcome of Left Ventricular Remodeling in ST Segment Myocardial Infarction Patients After pPCI
To detect long-term effects of left ventricular remodeling in STEMI patients undergoing PPCI. And to evaluate outcome.
- Trial name
- NCT03888781
- Testing
- Echocardiography
- Volunteers
- 127 people
- Sponsor
- Assiut University
Alzheimer Disease and Related Dementias
Promoting Positive Care Interactions (PPCI) in Assisted Living
The overall aim of this study is to pilot test Promoting Positive Care Interactions (PPCI) with the goal of establishing a feasible and culturally responsive approach to optimize care interactions between staff (nursing…
- Trial name
- PPCI (NCT05618834)
- Testing
- Promoting Positive Care Interactions (PPCI), PPCI-Staff Education Only (EO)
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Penn State University
LVOT VTI, STEMI - ST Elevation Myocardial Infarction (MI)
Prognostic Value of the LVOT VTI in STEMI Patients Undergoing PPCI
To determine whether LVOT VTI < 15 cm predicts the development of in-hospital cardiogenic shock or need for vasopressors in STEMI patients undergoing primary PCI.
- Conditions
- LVOT VTI, STEMI - ST Elevation Myocardial Infarction (MI), Primary Percutaneous Coronary Intervention
- Trial name
- NCT07114978
- Testing
- Echocardiography
- Where
- Egypt
- Volunteers
- 125 people
- Sponsor
- Assiut University
Segment Elevation Myocardial Infarction (STEMI)
NATURE (EnVast as an Adjunct PPCI in Subjects Presenting With STEMI)
This study is designed to compare the safety and effectiveness of blood clot (thrombus) removal in subjects presenting with ST-segment elevation myocardial infarction (STEMI) with the enVast coronary system versus conventional…
- Trial name
- NATURE (NCT04969471)
- Testing
- enVast stent, conventional treatment
- Where
- 11 sites in Italy, Netherlands and 1 more
- Volunteers
- 148 people
- Sponsor
- Vesalio
Acute Anterior ST-Segment Elevation Myocardial Infarction
A Research Study to Evaluate the Efficacy and Safety of SGC001 in Patients With Anterior Wall ST-Segment Elevation Myocardial Infarction
This is a multicenter, randomized, double-blind, placebo-controlled, single-dose, Phase II clinical study to evaluate the efficacy, safety, and pharmacokinetic (PK) characteristics of SGC001 injection administered in addition to…
- Trial name
- NCT07306182
- Testing
- SGC001 injection
- Where
- China
- Volunteers
- 210 people
- Sponsor
- Beijing Sungen Biomedical Technology Co., Ltd
Acute Myocardial Infarction
Is the 4MGS a Useful Outcome Measure Post-PPCI
This study aims to assess usual walking speed (4-metre gait speed) in patients undergoing primary percutaneous coronary intervention (PCI) for acute myocardial infarction and to assess whether this can predict future…
- Trial name
- NCT02261324
- Where
- United Kingdom
- Volunteers
- 560 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
STEMI, Diabete Mellitus
Inflammatory and Hematological Indices in Diabetic STEMI Patients Undergoing Primary PCI
ST-segment Elevation Myocardial Infarction (STEMI) remains a major cause of mortality despite the adoption of Primary Percutaneous Coronary Intervention (PPCI) as the standard treatment.
- Trial name
- NCT07155395
- Volunteers
- 1,000 people
- Sponsor
- Assiut University
STEMI
Platelet Inhibition to Target Reperfusion Injury
There remains a clinical need to improve health outcomes in patients with ischemic heart disease (IHD) the leading cause of death and disability in Singapore and worldwide.
- Trial name
- PITRI (NCT03102723)
- Testing
- Cangrelor
- Where
- 5 sites in Singapore
- Volunteers
- 228 people
- Sponsor
- National Heart Centre Singapore
Embolic Stroke, Postoperative Cognitive Dysfunction
Perfusion Pressure Cerebral Infarction Trial (PPCI)
STUDY HYPOTHESIS In cardiac surgery the volume of perioperative cerebral infarctions can be reduced by increasing mean arterial pressure (MAP) during the cardiopulmonary bypass procedure.
- Trial name
- PPCI (NCT02185885)
- Testing
- Increased bloodpressure during CPB.
- Where
- Denmark
- Volunteers
- 197 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
STEMI - ST Elevation Myocardial Infarction
Correlation Between Triglyceride Glucose Index and Residual SYNTAX Score in STEMI Patients Undergoing PPCI
The goal of this study To check correlation between triglyceride glucose (TyG) index and residual SYNTAX score (RSS) in STEMI patients undergoing PPCI. 2.
- Trial name
- NCT06642259
- Testing
- Echocardiography
- Volunteers
- 185 people
- Sponsor
- Assiut University
Coronary Heart Disease, ST Elevation Myocardial Infarction
Prognostic Value of the AMR Measured After PPCI in STEMI Patients
The goal of this observational study is to learn about in STEMI with Primary PCI Patients. The main questions it aims to answer are: To determine the value of AMR in predicting the long-term clinical prognosis of patients with…
- Trial name
- EARLYMYOAMR (NCT05653765)
- Where
- 5 sites in China
- Volunteers
- 2,663 people
- Sponsor
- Henan Institute of Cardiovascular Epidemiology