Clinical trials: PRP
Knee Osteoarthritis
Platelet Rich Plasma and Neural Prolotherapy Injections in Treating Knee Osteoarthritis
Osteoarthritis (OA) of the knees is the most common degenerative disorder seen in a rehabilitation outpatient clinic. It is characterized by metabolic, biochemical, and structural changes in the articular cartilage and the…
- Trial name
- NCT04006314
- Testing
- Autologous platelet rich plasma and dextrose solution.
- Where
- Taiwan
- Volunteers
- 24 people
- Sponsor
- Chang Gung Memorial Hospital
Diabetic Retinopathy
Intravitreal Bevacizumab vs Photocoagulation for Proliferative Diabetic Retinopathy
The purpose of the study is to evaluate the safety and efficacy of 2.5 mg of intravitreal bevacizumab in one eye, versus panretinal photocoagulation in the contralateral eye, for the treatment of patients with untreated symmetric…
- Trial name
- NCT00347698
- Testing
- intravitreal injection of bevacizumab, panretinal photocoagulation
- Where
- Mexico
- Sponsor
- Asociación para Evitar la Ceguera en México
Anal Fissure Chronic, PRP
Short Term Results of Platelet-rich Plasma in the Treatment of Chronic Anal Fissure
Autologous PRP currently has many uses in surgical and medical therapy. Compared with other regenerative therapies, PRP is easy-to-prepare, low-cost, and does not require complex equipment.
- Trial name
- NCT04320498
- Testing
- prp injection, Anrecta, sitz bath
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people
- Sponsor
- KTO Karatay University
Periorbital Hyperpigmentation
Efficacy of Platelet-rich Plasma (PRP) in the Treatment of Dark Circles Under the Eyes
10 ml of blood from each patient will be drawn. This blood specimen will be centrifuged in a specific way to get 1 ml of platelet rich plasma (PRP). PRP will be injected into the the skin under the eyes.
- Trial name
- NCT03114514
- Testing
- PRP
- Where
- Syria
- Volunteers
- 40 people
- Sponsor
- Damascus University
Diphtheria, Tetanus
Safety of PENTAXIM® Given as a Three-Dose Primary Vaccination at 2, 3, and 4 Months of Age in Infants in China
The study will assess the safety of Pentaxim® vaccine as a three-dose primary vaccination at 2, 3, and 4 months of age in order to meet the regulatory requirements for the license renewal as for any other product registered in…
- Conditions
- Diphtheria, Tetanus, Pertussis, Polio
- Trial name
- NCT01491087
- Testing
- DTacP IPV//PRP~T combined vaccine: PENTAXIM®
- Where
- 3 sites in China
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Ehlers-Danlos Syndrome Hypermobility Type (hEDS), Ehlers-Danlos Syndrome (EDS)
Regenerative Medicine for Joint Hypermobility and Instability
This clinical trial is designed to evaluate whether a stepwise injection-based treatment approach can reduce pain and improve function in adults with joint hypermobility, connective tissue laxity, and joint instability.
- Conditions
- Ehlers-Danlos Syndrome Hypermobility Type (hEDS), Ehlers-Danlos Syndrome (EDS), Joint Hypermobility, Joint Instability
- Trial name
- NCT07688096
- Testing
- Dextrose 20% Prolotherapy, Autologous Platelet-Rich Plasma, Doxycycline Hyclate Injectable (Investigational)
- Volunteers
- 100 people
- Sponsor
- Manhattan Pain Medicine, PLLC
Treatments of Striae Distensae
The Combination Therapy of Nanofat Grafting and PRP Compared With Microfat Grafting and PRP Synergy in Treating Striae Distensae
Striae distensae is caused by the fracture and damage of the elastic fibers and collagen fibers, which is still a difficulty to overcome.
- Trial name
- NCT03807986
- Testing
- Nanofat grafting, Microfat grafting, Platelet-rich plasma (PRP) Injection
- Where
- China
- Volunteers
- 12 people
- Sponsor
- First Affiliated Hospital of Jinan University
Class II Division 1 Malocclusion
The Effect of Platelet-rich Plasma on the Rate and Type of Orthodontic Tooth Movement
This study aims to assess the effect of PRP on the rate and type of OTM during en-masse frictionless retraction of maxillary anterior teeth using a segmental arch technique.
- Trial name
- NCT06133361
- Testing
- PRP injection, En-masse retraction of upper anterior teeth
- Where
- Syria
- Volunteers
- 30 people
- Sponsor
- Damascus University
Female Pattern Hair Loss
Successful Treatment of Female Pattern Hair Loss With Injection of Nanofat With and Without Platelet-Rich Plasma
Background: FPHL is a chronic progressive condition that necessitates lifelong management. Over time, patients who respond to conventional therapy may experience a decrease in the effectiveness of their treatment and may require…
- Trial name
- NCT07096323
- Testing
- Nanofat only, Nanofat mixed with PRP
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Discogenic Pain
Safety and Efficacy of PRP for Treatment of Disc Pain
This is a multi-center, randomized, controlled, double-blind clinical trial comparing hemocyte autograft (platelet rich plasma) to control injection (placebo) in subjects with reported cervical, thoracic or lumbar pain for at…
- Trial name
- NCT04064866
- Testing
- High yield pure PRP, ProPlaz PPC
- Where
- 7 sites in United States
- Volunteers
- 27 people
- Sponsor
- Neurological Associates of West Los Angeles
C.Surgical Procedure; Cardiac
Prospective Trial of Autologous Platelet Rich Plasma in Aortic Surgery
The purpose of this study is to determine whether autologous platelet rich plasma (APRP)is effective in reducing allogeneic blood transfusions during aortic surgery using deep hypothermic circulatory arrest.
- Trial name
- NCT02513862
- Testing
- Autologous Platelet-Rich Plasma Harvest Technique
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Hongwen Ji
Androgenic Alopecia
Condensed Nanofat Grafting for Treatment of Androgenetic Alopecia
Nowadays, multiple treatment modalities have been applied clinically to treat androgenic alopecia, such as Follicular unit transplantation(FUT), finasteride, platelet-rich plasma injection(PRP), etc.
- Trial name
- NCT03506503
- Testing
- Nanofat grafting
- Where
- China
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Jinan University Guangzhou
Diabetic Retinopathy
ETDRS PRP With IVR Versus Retinal Photocoagulation Targeted to Ischemic Retina With IVR for the Treatment of PDR
Purpose: To compare panretinal photocoagulation (PRP) as described in ETDRS Study combined with intravitreal injection of ranibizumab (IVR) (ETDRS-PRP group) and retinal photocoagulation targeted to ischemic retina combined with…
- Trial name
- NCT03904056
- Testing
- ISQ-RP, ETDRS-PRP group
- Volunteers
- 23 people
- Sponsor
- São Paulo State University
Knee Osteoarthritis
Treatment of Osteoarthritis by Intra-articular Injection of Bone Marrow Mesenchymal Stem Cells With Platelet Rich Plasma
Purpose: To determine the safety, feasibility and effectiveness (clinical and radiological) of intra-articular administration of autologous mesenchymal stem cells (MSCs) with platelet richa plasma (PRGF) in patients with knee…
- Trial name
- CMM-PRGF/ART (NCT02365142)
- Testing
- 100 million Bone marrow mesenchimal stem cells, Platelet Rich plasma (PRGF)
- Where
- 2 sites in Spain
- Volunteers
- 38 people
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Recurrent Implantation Failure, Endometrial Receptivity Disorders
Experimental Study on the Use of Intrauterine Infusion of Autologous Platelet-rich Plasma (PRGF-IUI) in Patients With Recurrent Implantation Failure and/or Refractory Thin Endometrium
Endometrial receptivity is a key determinant of success in assisted reproductive technology (ART). A significant proportion of patients experience repeated implantation failure despite euploid embryos and adequate laboratory…
- Conditions
- Recurrent Implantation Failure, Endometrial Receptivity Disorders, Embryo Implantation, Platelet-Rich Plasma
- Trial name
- PMA_PREPAIRE (NCT07455773)
- Testing
- Intrauterine Platelet-Rich Plasma (PRP) Infusion, Hormone Replacement Therapy (HRT)
- Volunteers
- 80 people
- Sponsor
- Azienda Sanitaria Locale di Asti
Plantar Fasciitis
Treatment of Plantar Fasciitis With Platelet Rich Plasma
The purpose of this investigator-initiated study is to clinically evaluate the efficacy of a new treatment for plantar fasciitis. This treatment consists of a platelet rich plasma injection into the origin of the plantar fascia.
- Trial name
- NCT01127672
- Testing
- platelet rich plasma, corticosteroid injection
- Where
- United States
- Sponsor
- Loma Linda University
Menopause, Menopause Ovarian Failure
Stem Cell Therapy and Growth Factor Ovarian in Vitro Activation
SEGOVA procedure includes - Stem cell therapy, G - Growth factor Platelet Plasma Rich therapy and in Vitro Activation of the ovaries.
- Conditions
- Menopause, Menopause Ovarian Failure, Ovarian Failure, Premature Ovarian Failure
- Trial name
- SEGOVA (NCT04009473)
- Testing
- SEGOVA procedure
- Where
- 3 sites in Malta, North Macedonia and 1 more
- Volunteers
- 100 people
- Sponsor
- Forever Young d.o.o.
Anterior Cruciate Ligament Tear, Posterior Cruciate Ligament Tear
Effect of Physical Therapy and/or Platelet Rich Plasma Injection in People With Knee Cruciate Ligament Injuries
Background: The anterior cruciate ligament(ACL) , one of the major ligaments in the knee joint which connects the posterior aspect of the lateral femoral condyle to the anterior intercondylar area of the tibia.
- Trial name
- NCT06233305
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Taipei Hospital, Ministry of Health and Welfare
Ebola Virus Disease, Marburg Virus Disease
Evaluation of Safety, Tolerability and Immune Responses of Ebola-S and Marburg Vaccines in Healthy Adults
Primary Objective: To evaluate the safety and tolerability of cAd3-EBO-S and cAd3 Marburg vaccines when administered Intramuscular (IM) at a dose of 1 x 10^11 particle units (PU) to healthy adults.
- Trial name
- NCT04723602
- Testing
- cAd3-Marburg, cAd3-EBO-S
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Albert B. Sabin Vaccine Institute
Carpal Tunnel Syndrome
Ultrasound-guided PRP Versus Steroid Injections in Management of Carpal Tunnel Syndrome
Patients will be randomly divided into 3 equal groups: Group I received ultrasound guided injection of 2 mL PRP into the affected carpal tunnel.
- Trial name
- NCT04434105
- Testing
- platlet rich plasma (PRP), Triamcinolone Acetonide, Saline
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University