Clinical trials: PTCA
In-Stent Restenosis
P E P C A D II, The Paclitaxel-Eluting PTCA-Balloon Catheter in Coronary Artery Disease to Treat In-Stent Restenoses
The aim of the study is to assess the safety and efficacy of the Paclitaxel-eluting PTCA-balloon in the treatment of in-stent restenoses in native coronary arteries with reference diameters between 2.5 mm and 3.5 mm and ≤ 22 mm…
- Trial name
- NCT00393315
- Testing
- paclitaxel coated balloon catheter
- Where
- 10 sites in Germany
- Volunteers
- 120 people
- Sponsor
- University Hospital, Saarland
Coronary Arteriosclerosis
Scoreflex TRIO - Scoring PTCA Catheter
To evaluate the acute safety and device procedural success of the Scoreflex TRIO Scoring PTCA catheters versus Scoreflex NC Scoring PTCA catheters in subjects with stenotic coronary arteries during percutaneous coronary…
- Trial name
- NCT05929313
- Testing
- OrbusNeich Scoreflex TRIO, OrbusNeich Scoreflex NC
- Where
- 4 sites in China
- Volunteers
- 210 people
- Sponsor
- OrbusNeich
Acute Coronary Syndrome, Percutaneous Transluminal Coronary Angioplasty
Establish a Telecare Model of Acute Coronary Syndrome Patient With Heart Stent Implantation by a Non-invasive Wearable Device and Artificial Intelligence Cloud to Reducing Medical Adverse Events.
Heart disease is still one of the world's most important health problems, and it ranks second among the top ten causes of death among Taiwan.
- Trial name
- NCT04455568
- Testing
- use EKG Wisdom bracelet
- Volunteers
- 400 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Myocardial Infarction, Occlusive Thrombus
Thrombus Aspiration for OcLuded Coronary Artery Enhanced With Distal Injection Of Abciximab
Aims: (to prove that) The distal injection of IIb IIIa platelet receptor blocker to the thrombus occlusion is better than normal injection during primary percutaneous intervention (PCI) for the treatment of acute myocardial…
- Trial name
- TOLEDO1 (NCT01383785)
- Testing
- Intracoronary direct injection, Intracoronary and distal injection by aspiration device, Intracoronary distal injection by aspiration catheter device
- Where
- Spain
- Volunteers
- 186 people
- Sponsor
- Hospital Virgen de la Salud
Coronary Artery Disease (CAD) (E.G., Angina, Myocardial Infarction, and Atherosclerotic Heart Disease (ASHD))
MIRAGE Study: Clinical Outcomes of the Mamba Sirolimus-Eluting PTCA Balloon
This Clinical Evaluation Report (CER) covers the Mamba Sirolimus-Eluting PTCA Balloon catheter intended for the treatment of coronary artery disease in de novo or in-stent restenosis lesions.
- Trial name
- NCT07326735
- Testing
- Mamba Sirolimus-Eluting PTCA Balloon, Percutaneous Coronary Angioplasty with Sirolimus-Coated Balloon
- Where
- 2 sites in Burma, Malaysia
- Volunteers
- 360 people
- Sponsor
- Frisch Medical Device Private Limited
Cardiac Catheterization
Improvement of Periprocedural Guidewire Management for Cardiac Catheterization (PTCA)
Periprocedural management of guidewire placement and removal in patients needing cardiac catheterization by use of marking of the access site and removal procedure due to a graduated scheme
- Trial name
- NCT00825331
- Where
- Germany
- Sponsor
- RWTH Aachen University
Coronary Artery Stenosis, Coronary Artery Disease
Evaluate the Clinical Efficacy and Safety of Non-Compliant PTCA Balloon Dilatation Catheter
This multi-center, retrospective study included patients diagnosed with coronary artery stenosis treated with NC PTCA balloons between January 2026 and March 2026 at three real-world centers in central China.
- Conditions
- Coronary Artery Stenosis, Coronary Artery Disease, Coronary Balloon
- Trial name
- NCT07855003
- Testing
- balloon angioplasty
- Where
- 3 sites in China
- Volunteers
- 200 people
- Sponsor
- TEDA International Cardiovascular Hospital
Acute Myocardial Infarction
Bivalirudin in Acute Myocardial Infarction
The purpose of the study is to evaluate the efficacy and safety of bivalirudin in AMI patients with DES. This is a prospective, randomized, single-blind, active drug controlled multicenter clinical research and the study would…
- Trial name
- NCT02897037
- Testing
- Bivalirudin, heparin
- Where
- China
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Shenzhen Salubris Pharmaceuticals Co., Ltd.
Myocardial Ischemia
RAdiation Dose In percutAneuos Coronary Procedures Through TransradIal apprOach Using Dedicated radiatioN Shields
During percutaneous coronary interventions standard operator radio-protection is generally ensured using a lead apron, a thyroid lead collar, low leaded flaps, an upper mobile leaded glass suspended from the ceiling and leaded…
- Trial name
- RADIATION (NCT01839162)
- Testing
- Coronary angiography, PCI, Right approach
- Where
- Italy
- Volunteers
- 452 people
- Sponsor
- Ospedale Sandro Pertini, Roma
Myocardial Infarction, Percutaneous Transluminal Coronary Angioplasty
Integration of Telemedicine and Home-Based Cardiac Rehabilitation: Feasibility, Efficacy, and Adherence
The aim of this study is to evaluate feasibility, efficacy, and adherence of home-based cardiac rehabilitation with the integration of telemedicine.
- Conditions
- Myocardial Infarction, Percutaneous Transluminal Coronary Angioplasty, Coronary Artery Bypass, Stable Angina
- Trial name
- NCT05972070
- Testing
- ROMTech Portable Connect
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- ROM Technologies, INC
Coronary Artery Disease, Coronary Artery Stenosis
Healthy Endothelial Accelerated Lining Inhibits Neointimal Growth
This is a multi-center, prospective, non-randomized study. Approximately 90 patients from up to 16 centers will be entered in the study. Patients will be followed clinically for up to 5 years post-procedure.
- Trial name
- NCT00349895
- Testing
- Coronary stent implantation
- Where
- 15 sites in Austria, Belgium and 4 more
- Volunteers
- 100 people
- Sponsor
- OrbusNeich
a Myocardial Infarction, Coronary Artery Bypass Graft Surgery Percutaneous Transluminal Coronary Angioplasty Stent Placement
The Effects of an Intensive Lifestyle Modification Program on Carotid Artery Intima-Media Thickness
The objective of this study is to evaluate the effect of the Ornish Program on cardiovascular disease as measured by the IMT of the common carotid artery, and to compare this effect to outcomes from patients participating in…
- Trial name
- NCT00243581
- Testing
- Dean Ornish Heart Disease Reversing Program
- Sponsor
- SwedishAmerican Health System
Acute Coronary Syndrome, Myocardial Infarction
Clopidogrel and the Optimization of Gastrointestinal Events (COGENT-1)
The purpose of the COGENT-1 clinical trial is to determine whether CGT-2168 (clopidogrel and omeprazole) compared to clopidogrel is safe and effective in reducing the incidence of gastrointestinal bleeding and symptomatic ulcer…
- Conditions
- Acute Coronary Syndrome, Myocardial Infarction, Coronary Artery Disease, Percutaneous Coronary Intervention
- Trial name
- COGENT-1 (NCT00557921)
- Testing
- CGT-2168 (clopidogrel 75 mg/omeprazole 20 mg) and aspirin, Plavix (clopidogrel 75 mg) and aspirin
- Where
- 491 sites in United States, Australia and 14 more
- Volunteers
- 5,000 people
- Sponsor
- Cogentus Pharmaceuticals
Coronary Artery Disease(CAD)
Safety and Efficacy of GENOSS® DCB With a Shellac Plus Vitamin E Excipient in Patients With De Novo Lesion
The GENOSS PCB-De Novo study aims to evaluate the long-term efficacy and safety of a paclitaxel-coated balloon catheter containing shellac and vitamin E excipients (Genoss® DCB) in patients with De novo small coronary artery…
- Trial name
- PCB-De Novo (NCT07158307)
- Where
- South Korea
- Volunteers
- 3,000 people
- Sponsor
- Genoss Co., Ltd.
Myocardial Infarction
Efficacy Study on Early Versus Late Abciximab Administration During Primary Coronary Angioplasty
Abciximab has been demonstrated to improve outcome when administered during primary angioplasty in patients with acute myocardial infarction.
- Trial name
- NCT00354406
- Testing
- abciximab
- Where
- Italy
- Volunteers
- 110 people
- Sponsor
- University of Pisa
Coronary Artery Disease
Balloon Elution and Late Loss Optimization (BELLO) Study
Prospective multicentre randomized (1:1) investigator initiated study, in which consecutive patients undergoing percutaneous revascularization of small coronary vessels will be assigned to one of the two study arms: 1.
- Trial name
- BELLO (NCT01086579)
- Testing
- IN.PACT Falcon paclitaxel eluting balloon (Drug eluting balloon), Taxus (Paclitaxel eluting stent)
- Where
- Italy
- Volunteers
- 182 people
- Sponsor
- Fondazione Evidence per Attività e Ricerche Cardiovascolari ONLUS
Acute Myocardial Infarction
Safety and Efficacy of Bone Marrow Cell Transplantation in Humans Myocardial Infarction
We will study in a prospective randomised fashion 50 patients who will be treated by intracoronary transplantation of autologous, mononuclear bone marrow cells (BMCs) in addition to standard therapy after MI or standard therapy.
- Trial name
- CARDIAC (NCT00437710)
- Testing
- cell therapy, bone marrow derived stem cell
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Azienda Unita Sanitaria Locale di Piacenza
Myocardial Ischemia, Coronary Arterial Disease (CAD)
Effectiveness of Inspiratory Muscle Training for People With Ischemic Heart Disease Revascularized by Percutaneous Transluminal Coronary Angioplasty.
Myocardial Ischemia (MI) consists of the narrowing of the internal lumen of the arteries that perfuse the heart. As the section of the artery decreases, so does the blood flow and therefore the supply of oxygen to the myocardium…
- Trial name
- CARDIOINSPIRE (NCT06681740)
- Testing
- Inspiratory muscle training
- Where
- Spain
- Volunteers
- 72 people
- Sponsor
- University of Cadiz
Coronary Artery Disease
Anticoagulant Treatments and Percutaneous Coronary Angioplasty
The purpose of this study is to determine whether adjunction of intravenous anticoagulant therapy (enoxaparin, HNF, bivalirudin) to antiaggregation with clopidogrel and aspirin improves in-hospital results of percutaneous…
- Trial name
- TACA (NCT00669149)
- Testing
- clopidogrel + aspirin, heparin + clopidogrel + aspirin, enoxaparin + clopidogrel + aspirin
- Where
- France
- Volunteers
- 99 people
- Sponsor
- Centre Hospitalier de PAU
Acute Coronary Syndrome
Same-Day Discharge After Coronary Percutaneous Transluminal Coronary Angioplasty (PTCA)
Same day discharge is safe and feasible in selected troponin negative patients undergoing coronary planned percutaneous coronary intervention (PCI) or ad hoc PCI via the transfemoral approach.
- Trial name
- GREECE (NCT01068119)
- Testing
- Same-day discharge
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Piedmont Healthcare