Clinical trials: PTSD
Chronic Pain, Chronic Pain Syndrome
Outcomes Mandate National Integration With Cannabis as Medicine
This will be a multistate, multicenter clinical study to determine the efficacy and safety of medical cannabis for a wide variety of chronic medical conditions.
- Conditions
- Chronic Pain, Chronic Pain Syndrome, Chronic Pain Due to Injury, Chronic Pain Due to Trauma
- Trial name
- OMNI-Can (NCT03944447)
- Testing
- Cannabis, Medical, RYAH-Medtech Inhaler
- Where
- 17 sites in United States
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- OMNI Medical Services, LLC
Post Traumatic Stress Disorder, Postoperative Complications
PTSD of Surgeons or Anesthesiologists on Prognosis of Surgical Patients
The objective of this prospective cohort study is to explore the association between the development of post-traumatic stress disorder (PTSD) in surgeons and anesthesiologists and postoperative prognosis in surgical patients they…
- Conditions
- Post Traumatic Stress Disorder, Postoperative Complications, COVID-19
- Trial name
- NCT05732116
- Testing
- PTSD
- Where
- 2 sites in China
- Volunteers
- 356 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
PTSD
Effects of Methylphenidate (Ritalin®) on the Neural Basis of Anxiety
In the present study, investigator will investigate the effects of methylphenidate (40 mg) on mPFC activity in healthy male volunteers during fear extinction using functional magnetic resonance imaging (fMRI).
- Trial name
- NCT02021214
- Testing
- Methylphenidate
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Mental Health Issue, Mental Stress
Evaluating Implementation and Impact of PeerOnCall, a Mobile Health Approach to Peer Support for Canadian Public Safety Personnel
A prospective cohort study design will be implemented across four sectors and multiple organizations sites to evaluate implementation and impact of the apps.
- Conditions
- Mental Health Issue, Mental Stress, Post Traumatic Stress Disorder
- Trial name
- NCT05429619
- Testing
- PeerOnCall
- Where
- 3 sites in Canada
- Volunteers
- 950 people, healthy volunteers welcome
- Sponsor
- McMaster University
Posttraumatic Stress Disorder
Military to Civilian: Trial of an Intervention to Promote Postdeployment Reintegration
Veterans returning from combat deployments face the interrelated challenges of processing their combat experiences and transitioning back to civilian life.
- Trial name
- M2C (NCT00640445)
- Testing
- Expressive Writing, Control Writing
- Where
- United States
- Volunteers
- 1,292 people, healthy volunteers welcome
- Sponsor
- Minneapolis Veterans Affairs Medical Center
Post-Traumatic Stress Disorder, Combat Disorders
Trauma Management Therapy for OEF and OIF Combat Veterans
This trial will evaluate the efficacy and efficiency of Trauma Management Therapy (TMT; Frueh, Turner, Beidel, 1996; Beidel, Frueh, Uhde, under preparation), which combines individual virtual reality (VR) assisted exposure…
- Trial name
- TMT (NCT02809326)
- Testing
- 17 week Exposure Therapy Control Arm, Trauma Management Therapy, Intensive 3-Week Trauma Management Therapy
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Chronic Posttraumatic Stress Disorder
Enhancing Exposure Therapy for Post-traumatic Stress Disorder
This study is investigating a new brief psychotherapy for post-traumatic stress disorder (PTSD) which, modifies an already proven psychotherapy for PTSD by adding two new components and modifying several others.
- Trial name
- NCT01574118
- Testing
- Revisiting the Trauma memories, Processing the trauma memories, Psychoeducation
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
PTSD and Trauma-related Symptoms, Cognitive Decline in Older Adults
Acute Effects of Estradiol Administration on Brain Function During Fear Learning
The goal of current study is to better understand how fear is processed in the brain and how these processes are influenced by cognition and hormones.
- Conditions
- PTSD and Trauma-related Symptoms, Cognitive Decline in Older Adults, Post Menopausal Women
- Trial name
- EstroFearGen (NCT07737613)
- Testing
- estradiol
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Posttraumatic Stress Disorder, Depression
Yoga Breath Program and Client-Centered Exposure for Relief of PTSD in Tsunami Victims
Study hypothesis: that a standardized course of Eastern practices (Breath Water Sound Course -BWS) will significantly relieve PTSD and depression in tsunami victims.
- Trial name
- NCT00290225
- Testing
- Breath Water Sound Course and Traumatic Incident Reduction
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Victim Services Center, Miami
Acute Myocardial Infarction, Heart Attack
Acute Coronary Syndrome and Care-Seeking Delay: A Web Based Behavioral Study
The primary aim of this study is to increase our understanding of care-seeking behavior surrounding heart attacks or acute coronary syndromes [ACS].
- Conditions
- Acute Myocardial Infarction, Heart Attack, Acute Coronary Syndrome, Unstable Angina
- Trial name
- NCT01407146
- Where
- United States
- Volunteers
- 2,381 people, healthy volunteers welcome
- Sponsor
- Yale University
Post Traumatic Stress Disorder
Feasibility Trial of Narrative Exposure Therapy (NET) for Posttraumatic Stress Disorder (PTSD) During Pregnancy
Posttraumatic stress disorder (PTSD) affects up to 35% of pregnant trauma survivors. Moreover, prenatal PTSD rates are up to 4 times higher among communities of color compared to white populations.
- Trial name
- NET (NCT04525469)
- Testing
- Narrative Exposure Therapy
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Emotional Disorder
Unified Protocol for Emotional Problems in Victims of the Armed Conflict in Colombia
The present study aims at evaluating the effects of a CBT intervention, a cultural adaptation of the Unified Protocol for the Trans-diagnostic Treatment of Emotional Disorders (UP) in victims of the Colombian armed conflict.
- Trial name
- NCT03127982
- Testing
- Unified Protocol
- Where
- Colombia
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- University of Los Andes, Columbia
Traumatic Brain Injury, Post Traumatic Stress Disorder
A Study of Brain Aging in Vietnam War Veterans
Traumatic brain injury (TBI) and post traumatic stress disorder (PTSD) are common combat related problems and may be associated with a greater risk of Alzheimer's disease (AD).
- Conditions
- Traumatic Brain Injury, Post Traumatic Stress Disorder, Alzheimer's Disease, Mild Cognitive Impairment
- Trial name
- DOD-ADNI (NCT01687153)
- Where
- 19 sites in United States
- Volunteers
- 289 people, healthy volunteers welcome
- Sponsor
- University of Southern California
TBI (Traumatic Brain Injury), PTSD
Translational Research Center for TBI and Stress Disorders: Virtual Assessment of Deployment Trauma and Rehabilitation
For this clinical demonstration study, Veterans will be assessed with a battery of questionnaires/surveys and a 1:1 clinical interview with a V-TRACTS psychologist to target domains of head injury, psychological trauma…
- Trial name
- V-TRACTS (NCT04723745)
- Testing
- V-TRACTS Assessment/Feedback, OPTIONAL Brief Assessment of Thinking, OPTIONAL STEP-Home-Brief
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- VA Boston Healthcare System
Posttraumatic Stress Disorders
Cognitive Training for Post Traumatic Stress Disorder: Effects on Cognitive, Emotional, and Brain Function
The purpose of this pilot study is to determine the effects of computer-based training in executive functioning compared to word games on cognitive and emotional aspects of combat-related PTSD.
- Trial name
- NCT01644851
- Testing
- Executive function training
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Missouri, Kansas City
Post Traumatic Stress Disorder
Implementation of a Post-traumatic Stress Disorder PREvention Program Within the French ARmy
Post-Traumatic Stress Disorder (PTSD) is a mental health condition that's triggered by a terrifying event perceived as a life threatening - either experiencing it or witnessing it.
- Trial name
- PREPAR (NCT05094531)
- Testing
- Primary prevention programm
- Where
- France
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Psychological Trauma, PTSD
Study of Yoga and Mindfulness for Psychological and Physical Wellness
The study rationale is to analyze the extent to which adult U.S. or non U.S. veterans or active duty military personnel who participate in the Yoga for Men (YfM) online Yoga and meditation classes report changes in symptoms of…
- Trial name
- NCT03059095
- Testing
- Yoga & Meditation
- Volunteers
- 335 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Depression, Post-traumatic Stress Disorder
Evaluating Implementation Strategies to Scale-up Transdiagnostic Evidence-based Mental Health Care in Zambia
This study utilizes a Hybrid Type 1 multi-arm parallel group randomized control design to compare the effectiveness of an evidence-based treatment (CETA) delivered either in-person or via telephone, compared with a treatment as…
- Conditions
- Depression, Post-traumatic Stress Disorder, Anxiety, Substance Abuse
- Trial name
- NCT03458039
- Testing
- In-person CETA, Telephone CETA, Treatment as Usual (TAU)
- Where
- Zambia
- Volunteers
- 456 people, healthy volunteers welcome
- Sponsor
- Centre for Infectious Disease Research in Zambia
Post Traumatic Stress Disorder, Depression
Randomized Control Trial on Trauma Focused CBT in Zambia
The purpose of this study is to study the effectiveness of Trauma Focused Cognitive Behavioral Therapy in subset of children who are affected by trauma with significant mental health symptomatology in order to 1) examine the…
- Conditions
- Post Traumatic Stress Disorder, Depression, Risk Behaviors
- Trial name
- NCT01624298
- Testing
- Trauma Focused Cognitive Behavioral Therapy
- Where
- Zambia
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Intrusive Thoughts, Post Traumatic Stress Disorder
Reduction of Trauma-induced Intrusions and Amygdala Hyperreactivity Via Non-invasive Brain Stimulation
The study will focus on the modulation of intrusive memories via functional magnetic resonance imaging (fMRI)-guided repetitive transcranial magnetic stimulation of the dorsolateral prefrontal cortex (dlPFC) directly after…
- Trial name
- COOL (NCT04325087)
- Testing
- iTBS
- Where
- Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bonn