Clinical trials: PTSD
Post Traumatic Stress Disorders
Post Traumatic Stress Disorder and Neural Mechanisms Involved in Its Treatment
The post traumatic stress disorder PTSD arises when the physiological response to stress does not come to its term. This study aims to explore the cognitive, psycho physiological and cerebral mechanisms involved in PTSD, in fear…
- Trial name
- NCT00893568
- Testing
- resonance magnetic imaging (fMRI),
- Where
- France
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille
PTSD
A Lay-Led Intervention for War and Refugee Related Trauma
This study will examine the initial efficacy and feasibility of a program called Islamic Trauma Healing by conducting a small RCT (N = 60) comparing Islamic Trauma Healing in an U.S.
- Trial name
- NCT03502278
- Testing
- Islamic Trauma Healing
- Where
- 2 sites in United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University of Washington
Adderall, PTSD
Effects of Stimulant Medications in PTSD
While there have been advances in understanding post-traumatic stress disorder (PTSD) as a disorder and its biological features, unfortunately only one out of five traumatized persons with PTSD reach remission after cycling…
- Conditions
- Adderall, PTSD, Post Traumatic Stress Disorder
- Trial name
- SMP (NCT07664631)
- Testing
- Adderall
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Posttraumatic Stress Disorder
Relaxation Response Training for PTSD Prevention in US Military Personnel
The purposes of this study are to evaluate the acceptability and utility of a mind-body intervention on a convenience sample of Soldiers (n=120) who have screened positive through RESPECT-MIL for symptoms that may lead to…
- Trial name
- RR (NCT01725854)
- Testing
- Relaxation Response training
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- William Beaumont Army Medical Center
Post Traumatic Stress Disorder
Quantifying the Efficacy and Role of Service Dogs for Military Veterans With PTSD
The purpose of this study is to quantify the therapeutic efficacy and role of trained service dogs on socio-emotional functioning among military veterans with posttraumatic stress disorder (PTSD).
- Trial name
- NCT03245814
- Testing
- Service Dog
- Where
- United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- University of Arizona
PTSD, Sleep Disorders
Cooperative Studies Program #563 - Prazosin and Combat Trauma PTSD
Background: Posttraumatic stress disorder (PTSD) is a debilitating and disabling mental disorder that afflicts at least 25% of Veterans who have suffered life-threatening war zone trauma.
- Trial name
- PACT (NCT00532493)
- Testing
- prazosin
- Where
- 15 sites in United States
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Post Traumatic Stress Disorder
PTSD Training for PCPs in a Virtual World
The overall goal of this project is improve access to and engagement in quality care for military service personnel and Veterans suffering with posttraumatic stress (PTS).
- Trial name
- VW (NCT03898271)
- Testing
- Virtual World
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- San Francisco Veterans Affairs Medical Center
Post-traumatic Stress Disorder (PTSD), Trauma and Stress Related Disorders
Grappling With Trauma: Brazilian Jiu-Jitsu for First Responders
This study explores whether participating in an 8-week Brazilian Jiu-Jitsu (BJJ) program is linked to changes in trauma-related symptoms among first responders.
- Conditions
- Post-traumatic Stress Disorder (PTSD), Trauma and Stress Related Disorders, Occupational Stress, Emotional Regulation Difficulties
- Trial name
- CAM-GRIP (NCT07783516)
- Testing
- Brazilian Jiu-Jitsu Program
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Sam Houston State University
Work Related Stress
Potential Benefits of the Somatic Psychoeducational Intervention
The goal of this clinical trial is to explore possible benefits and mechanisms through which the Somatic Psychoeducational Intervention can improve health and wellness in health care providers (HCP).
- Trial name
- NCT05766852
- Testing
- Somatic Psychoeducational Intervention
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Florida
PTSD
Exercise and Therapeutic Learning Among Women With PTSD
This study aims to test whether aerobic exercise performed after fear extinction learning improves the consolidation and subsequent recall of the learned safety memories (i.e., fear extinction memories) among adult women with…
- Trial name
- NCT04113798
- Testing
- Day 1 Assessments, Day 2 Fear Learning, Day 3 Fear Extinction
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Chronic Pain, PTSD
Management of Chronic Pain and PTSD in Gulf War Veterans With tDCS+Prolonged Exposure
Gulf War Veterans (a DoD/VA defined service era corresponding to the first Gulf War under operations Desert Storm and Desert Shield 1990-1991), especially those who present with Post-Traumatic Stress Disorder (PTSD), are…
- Trial name
- NCT04236284
- Testing
- Home-based tDCS, Prolonged Exposure Therapy
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Post Traumatic Stress Disorder, Cardiovascular Diseases
NightWare and Cardiovascular Health in Women With PTSD
The purpose of this study is to determine whether NightWare therapeutic intervention improves biomarkers of vascular and renal function in premenopausal women with PTSD-related nightmares, and examine whether these improvements…
- Conditions
- Post Traumatic Stress Disorder, Cardiovascular Diseases, Autonomic Dysfunction, Vascular Stiffness
- Trial name
- NCT07021014
- Testing
- NightWare
- Where
- 2 sites in United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Post-Traumatic Stress Disorder, Depression
Trial of Mental Health Treatment for Darfur Refugees in Cairo
The enormous global burden of mental illness has been estimated through the publication of the Global Burden of Disease Study, adding momentum to refugee mental health studies (1,2).
- Conditions
- Post-Traumatic Stress Disorder, Depression, Anger, Domestic Violence
- Trial name
- NCT00879853
- Testing
- Interpersonal Therapy
- Where
- Egypt
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Stress Disorders, Post-Traumatic
Psychological Symptom Change in Veterans After Six Sessions of EFT (Emotional Freedom Techniques)
EFT (Emotional Freedom Techniques) has been shown to significantly reduce post-traumatic stress disorder (PTSD) and other psychological symptoms such as anxiety and depression in a variety of clinical trials.
- Trial name
- NCT01117545
- Testing
- EFT (Emotional Freedom Techniques)
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Soul Medicine Institute
Complex Post-Traumatic Stress Disorder
Survive & Thrive Trial With Male Offenders
Previous research has concluded that prison populations have particularly high rates of interpersonal trauma. There is however concern that these issues have been largely overlooked and misunderstood in the work undertaken with…
- Trial name
- NCT04887168
- Testing
- Survive & Thrive
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Edinburgh Napier University
Anxiety, Posttraumatic Stress Disorder
School-based Practices in Arts and Resilience for Kids
This proposal will implement and test feasibility and efficacy of school-based art therapy and yoga/mindfulness programming to reduce mental health disparities and foster resilience in youth.
- Conditions
- Anxiety, Posttraumatic Stress Disorder, Trauma
- Trial name
- SPARK (NCT06945497)
- Testing
- Art Therapy, Yoga/Mindfulness
- Where
- 2 sites in United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Stress Disorders, Post-Traumatic
Neuroimmunological Model of Traumatic Memory
Traumatic events may lead to strong emotional episodic memories common in Post- Traumatic Stress Disorder(PTSD). Intense affect may inhibit efficacy of glutamatergic neurotransmission in two particular areas of the limbic system…
- Trial name
- NCT00396695
- Testing
- Blood test
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ziv Hospital
Alcohol Use Disorder, Post Traumatic Stress Disorder
Imaging Traumatic Stress and Alcohol Use Disorder With [18F]Bavarostat
The overall objective of this study it to use Positron Emission Tomography (PET) brain imaging and a radiotracer that measures the epigenetic marker Histone Deacetylase 6 (HDAC6) to examine HDAC6 expression in people with…
- Trial name
- NCT06371404
- Testing
- Bavarostat
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Yale University
PTSD
Effectiveness of Trauma Management Therapy and Prolonged Exposure Therapy
The purpose of this requirement is to identify an effective exposure psychotherapy paradigm for the treatment of Post-Traumatic Stress Disorder (PTSD) in active duty service members and veterans by comparing different exposure…
- Trial name
- NCT04549493
- Testing
- Exposure Therapy
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Post Traumatic Stress Disorder
Department of Defense PTSD Adaptive Platform Trial - Intervention A - Fluoxetine
This is a Phase 2 randomized, double-blinded, placebo-controlled study that will evaluate multiple potential pharmacotherapeutic interventions for PTSD utilizing an adaptive platform trial design.
- Trial name
- NCT05948553
- Testing
- Intervention A Fluoxetine Hydrochloride (HCl)
- Where
- 9 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Global Coalition for Adaptive Research