Clinical trials: PVI
Post-induction Hypotension (PIH), Geriatric Patient
Incidence and Risk Factors of Post-Induction Hypotension in Geriatric Cancer Patients
This observational clinical study aims to investigate the incidence and risk factors of post-induction hypotension (PIH) in geriatric cancer patients undergoing surgery under general anesthesia.
- Conditions
- Post-induction Hypotension (PIH), Geriatric Patient, Oncologic Disease, Hemodynamic Effects of General Anesthesia
- Trial name
- NCT07294040
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Dolunay ARIK
Paroxysmal Atrial Fibrillation
FIH of PFBalloon for PVI
The goal of this clinical trial is to assess the safety and effectiveness of a conformal pulsed field ablation (PFA) balloon catheter for pulmonary vein isolation (PVI) in patients with paroxysmal atrial fibrillation (AF).
- Trial name
- NCT07320976
- Testing
- PVI with a novel PFA catheter
- Where
- China
- Volunteers
- 35 people
- Sponsor
- The Third People's Hospital of Chengdu
Scoliosis, Spinal Fusion
Is Pleth Variability Index (PVI) a Surrogate for Pulse Pressure Variations (PPV) in Pediatric Spine Fusion (SF) Surgery?
Spine fusion is an involved procedure during which patients are at risk for significant intra-operative blood loss.This study will compare 2 ways of determining fluid status and response to fluid administration.
- Trial name
- NCT00994656
- Testing
- Masimo multi-wavelength pulse co-oximeter
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Children's Hospital of Philadelphia
Hypovolemia
Detection of Hypovolemia Using Pleth Variability Index (PVI)
The purpose with the planned study is to study Pleth Variability Index (PVI) as a non invasive indicator for mild hypovolemia during spontaneous breathing in healthy subjects.
- Trial name
- NCT01456559
- Testing
- Lower body negative pressure (LBNP)
- Where
- 2 sites in Sweden
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University Hospital, Linkoeping
Atrial Fibrillation (AF)
PVI Alone vs PVI With Posterior Wall Isolation for Pulse-Field Ablation in Persistent AF
To date, no optimal treatment has been established to improve outcomes in patients with persistent atrial fibrillation. The safety and efficacy of pulsed-field ablation (PFA) have been demonstrated in several studies, and its…
- Trial name
- POBI-PFA (NCT06929897)
- Testing
- Pulmonary Vein Isolation, Additional Left Atrial Posterior Wall Ablation, Non-PV trigger test
- Where
- South Korea
- Volunteers
- 482 people, healthy volunteers welcome
- Sponsor
- Ewha Womans University Mokdong Hospital
Atrial Fibrillation
Persistent AF Catheter Ablation: Re-PVI Vs. Re-PVI + Continuous Complex Activity Mapping and Ablation - AF-CAM
Major objective is to compare the efficacy of adding additional ablation step (targeting areas of complex, continuous electrical activity in LA) beyond Re-PVI during catheter ablation of Atrial Fibrillation (AF) in patients…
- Trial name
- AF-CAM (NCT05496088)
- Testing
- Re-PVI only, Re-PVI + substrate ablation
- Where
- 3 sites in Germany
- Volunteers
- 56 people
- Sponsor
- Asklepios proresearch
Intraoperative Bleeding in Lumbar Spine Surgery, Postoperative Pain in Lumbar Spine Surgery
Efficacy of Periarticular Vasoconstrictor Infiltration (PVI) in Reducing Bleeding and Postoperative Pain in Lumbar Fusion Surgery
This retrospective observational study evaluates the efficacy of periarticular vasoconstrictor infiltration (PVI) in reducing intraoperative bleeding and postoperative pain in adult patients undergoing lumbar fusion surgery at…
- Trial name
- NCT07530237
- Testing
- Periarticular Vasoconstrictor Infiltration
- Where
- Spain
- Volunteers
- 25 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Neurosurgery in Sitting Position
Dynamic Preload Indicators in Sitting Position
Intraoperative optimization of cardiac output using goal directed fluid challenge is associated with better outcome. Dynamic preload dependence indicators are well validated during surgery in supine position.
- Trial name
- NCT02000570
- Testing
- Sitting position (neurosurgery)
- Where
- France
- Volunteers
- 31 people
- Sponsor
- Hospices Civils de Lyon
Peripheral Arterial Disease
Robotic-Assisted Peripheral Intervention for Peripheral Arterial Disease
This study evaluates the performance of the CorPath 200 System to deliver guide wires and balloons to blockages in the arteries of the leg.
- Trial name
- RAPID (NCT02371785)
- Testing
- CorPath 200 System
- Where
- Austria
- Volunteers
- 20 people
- Sponsor
- Siemens Healthineers Endovascular Robotics, Inc.
Atrial Fibrillation
aMAZE Study: LAA Ligation Adjunctive to PVI for Persistent or Longstanding Persistent Atrial Fibrillation
This study is a prospective, multicenter, randomized (2:1) controlled study to evaluate the safety and effectiveness of the LARIAT System to percutaneously isolate and ligate the Left Atrial Appendage from the left atrium as an…
- Trial name
- aMAZE (NCT02513797)
- Testing
- LARIAT + PVI, Pulmonary Vein Isolation
- Where
- 53 sites in United States
- Volunteers
- 600 people
- Sponsor
- AtriCure, Inc.
Anesthesia, General, Fluid Therapy
Management of Intraoperative Fluids in Ambulatory Surgery
This is a single-center prospective randomized control trial (RCT) to determine whether the continuous monitoring of the plethysmographic variability index (PVI) during low-risk surgeries, can be used to optimize the…
- Conditions
- Anesthesia, General, Fluid Therapy, Ambulatory Surgical Procedures
- Trial name
- MIFAS (NCT03193320)
- Testing
- Fluid therapy protocol
- Where
- Venezuela
- Volunteers
- 243 people, healthy volunteers welcome
- Sponsor
- Policlinica Metropolitana
Atrial Fibrillation (AF), Atrial Fibrillation Patients Treated With the FARAPULSE™ PFA System
P-wave Duration and Local Potential as Predictors of AF Recurrence Following Pulmonary Vein Isolation
Atrial fibrillation (AF) is the most prevalent sustained cardiac arrhythmia worldwide and is associated with substantial morbidity, mortality, and healthcare utilization.
- Conditions
- Atrial Fibrillation (AF), Atrial Fibrillation Patients Treated With the FARAPULSE™ PFA System, Atrial Fibrillation (Paroxysmal), Pulmonary Vein Isolation
- Trial name
- FOLLOW-AF (NCT07471308)
- Testing
- AF Recurrence RIsk Assessment post pulmonary vein isolation
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- CathVision ApS
Validation of PVI in Tidal Volume Challenge Test
PVI for TVC Response
Determine the ability of changes in Plethysmographic Variability Index during tidal volume challenge to predict fluid responsiveness
- Trial name
- NCT04978909
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
Paroxysmal Atrial Fibrillation, Atrial Arrhythmia
Effectiveness Study of Circumferential vs. Segmental Ablation in Paroxysmal Atrial Fibrillation
This is a PI-initiated study that aims to evaluate the efficacy of two different methods of paroxysmal atrial fibrillation (PAF) ablation.
- Trial name
- PAF (NCT02106663)
- Testing
- Circumferential Pulmonary Vein Ablation, Segmental Pulmonary Vein Isolation
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- University of California, San Diego
Atrial Fibrillation
Effects of Mindfulness on Atrial Fibrillation
This study aims to investigate the effect of MUSE (R) Headbands on patients with Atrial Fibrillation who is awaiting pulmonary vein isolation ablation procedure. Patients are randomized in 2 arms.
- Trial name
- NCT02564302
- Testing
- MUSE Headband
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Newmarket Electrophysiology Research Group Inc
Atrial Fibrillation
Sole-Therapy Treatment of Atrial Fibrillation
RESTORE SR II is a feasibility study on the minimally invasive use of the AtriCure Bipolar System for PV Isolation on a beating heart for the treatment of all types of atrial fibrillation in a sole therapy operation (not…
- Trial name
- RESTORE SR II (NCT00566176)
- Testing
- Surgical Ablation using the AtriCure Bipolar System
- Where
- 5 sites in United States
- Volunteers
- 25 people
- Sponsor
- AtriCure, Inc.
Laparoscopic Colorectal Surgery, Acute Kidney Injury
The Effect of Fluid Management by Pleth Variability Index on Acute Kidney Injury in Obese Patients
This study was to find out whether laparoscopic colorectal surgery is detrimental to the kidneys via PVI monitoring. To detect the kidney injury, so-called kidney troponin NGAL ,which gives earlier information than creatin in…
- Trial name
- NCT03408834
- Testing
- pulse variability index
- Volunteers
- 29 people
- Sponsor
- Ankara University
Atrial Fibrillation Paroxysmal
Esophageal Temperature During PVI Using Q-DOT Micro
This study will assess how two different ablation strategies, using two different ablation catheters during catheter ablation for paroxysmal atrial fibrillation, affect the temperature of the esophagus during ablation, and the…
- Trial name
- NCT06392932
- Testing
- QDOT Micro ablation catheter, ST SF ablation catheter
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Cedars-Sinai Medical Center
Atrial Fibrillation
Prospective Evaluation of Biophysical Parameters as Long-term Predictors of Pulmonary Vein Isolation
Current, worldwide assessments of the prevalence of AF estimate that 33 million people are affected by this cardiac arrhythmia. As the most common sustained atrial arrhythmia, AF has a well-established association with systemic…
- Trial name
- MERCY (NCT05805189)
- Testing
- pulmonary vein (PV) isolation
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Maria Cecilia Hospital
Paroxysmal Atrial Fibrillation
The FARAPULSE FARA-Freedom Trial
The Post-Market Clinical Follow-Up trial is a prospective, multi-center, open-label, single-arm clinical follow-up study designed to provide long-term safety feasibility, effectiveness and performance of the FARAPULSE Pulsed…
- Trial name
- FARA-Freedom (NCT05072964)
- Testing
- FARAPULSE Pulsed Field Ablation System
- Where
- 13 sites in Belgium, Czechia and 4 more
- Volunteers
- 180 people
- Sponsor
- Boston Scientific Corporation