Clinical trials: PVI
Atrial Fibrillation
QDOT Based PVI for Atrial Fibrillation Treatment - The peQasus Study
PeQasus is a worldwide, retrospective, multicenter analysis focusing on QDOT based PVI. Data of at least 300 patients with QDOT based PVI will be collected. All data will be evaluated after anonymization.
- Trial name
- peQasus (NCT05710822)
- Testing
- pulmonary vein isolation
- Volunteers
- 300 people
- Sponsor
- University of Luebeck
Atrial Fibrillation
The Contact PVI Study: Use of Tissue Contact Data to Guide Atrial Fibrillation Ablation
This study aims to investigate the benefit of a new impedance-based computer software application during routine catheter ablation for atrial fibrillation, to see if this information improves short and long term electrical…
- Trial name
- NCT01629056
- Testing
- ablation, RF ablation
- Where
- United Kingdom
- Volunteers
- 148 people
- Sponsor
- Oxford University Hospitals NHS Trust
Cervical Cancer
Radiation Therapy With or Without Cisplatin or Fluorouracil in Treating Patients With Cancer of the Cervix
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.
- Trial name
- NCT00003078
- Testing
- cisplatin, fluorouracil, brachytherapy
- Where
- 66 sites in United States, Canada
- Volunteers
- 870 people
- Sponsor
- Gynecologic Oncology Group
Perioperative Care, Fluid Therapy
Paired Comparison of SVV and PVI Accuracy
This study will compare two operating-room monitors-stroke volume variation (SVV, from the arterial line) and the Pleth Variability Index (PVI, from the pulse oximeter)-to see which one more accurately predicts whether giving a…
- Conditions
- Perioperative Care, Fluid Therapy, Monitoring, Physiologic, Hemodynamics
- Trial name
- NCT07260890
- Testing
- Stroke Volume Variation (SVV) monitoring, Pleth Variability Index (PVI) monitoring
- Where
- South Korea
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Wonkwang University Hospital
Persistent Atrial Fibrillation
VEin of MArshall Ethanolization Vs Extended Pulmonary Vein PULSEd Field Ablation After Failed PVI for Persistent AF
The goal of this clinical trial is to compare two ablation techniques to treat patients with persistent atrial fibrillation (irregular and often very rapid heart rhythm).
- Trial name
- VEMAPULSE (NCT06383975)
- Testing
- Pulsed field ablation with posterior wall isolation, Radiofrequency ablation and vein of Marshall ethanolization
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Sebastien Knecht
Free Tissue Flaps
PVI Based Intraoperative Fluid Management in Head and Neck Free Flap Reconstructive Surgeries
Intraoperative fluid given according to BMI in group B and according to pulse oximeter- derived pleth variability index(MASIMO RAINBOW PULSE CO OXIMETRY) in group G.
- Trial name
- NCT03116178
- Testing
- Group G -PVI( Masimo co oximeter) guided fluid therapy, Group B- Body weight guided intravenous fluid @6-8ml/kg
- Volunteers
- 80 people
- Sponsor
- Rajiv Gandhi Cancer Institute & Research Center, India
Persistent Atrial Fibrillation
Comparison of Reverse Remodeling and PVI Versus CFAE and/or Linear Lesions and PVI for Persistent AF
The hypothesis of this study is that by facilitating reverse atrial remodeling with maintenance of sinus rhythm in the weeks preceding ablation makes it feasible to perform a simple pulmonary vein isolation (PVI) with results…
- Trial name
- NCT01877473
- Testing
- Ablation
- Where
- United States
- Sponsor
- Valley Health System
Atrial Fibrillation
Comparison of PVI Plus Catheter Ablation or PVI Alone for the Treatment of AFib for Patients With Paroxysmal Atrial Fibrillation
There is a need to compare the efficacy of PVI versus PVI plus catheter ablation, which includes ablation of complex fractionated atrial electrograms (CFAE) and linear lesions in the same procedure.
- Trial name
- NCT03115554
- Testing
- PVI Plus Catheter Ablation, PVI Alone
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Wake Forest University Health Sciences
Atrial Septal Defect
A Prospective Investigation of Pleth Variability Index (PVI) as a Dynamic Parameter of Fluid Responsiveness in Children
This study is designed to investigate the ability of pleth variability index (PVI) to non-invasively predict fluid responsiveness in mechanically ventilated children.
- Trial name
- NCT02276599
- Testing
- Volume expansion
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Brian Schloss
Intravascular Volume, Respiratory Changes
Fluid Management Study to Evaluate Changes in Intravascular Volume After Applying Various Pressure Levels on the Caval Vein
Fluid therapy optimization in the perioperative period has been considered as major contributor to improve oxygen delivery. A recent, noninvasive approach to estimate fluid requirements in the anesthetized patient with arterial…
- Trial name
- NCT01388998
- Testing
- Changes of difference in pulse pressure and plethysmography after applying various pressure levels on the caval vein
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- Johannes Gutenberg University Mainz
Fluid Overload
Comparison of PVI-guided Fluid Management With Traditional Fluid Management in Colorectal Surgery
The first objective of this study was to compare the traditional fluid management (TFM) with PVI guided goal-directed fluid management (GDFM) in terms of controlled intraoperative fluid volume, surgical end-point fluid balance…
- Trial name
- NCT03339895
- Testing
- pvı-guided, traditional-guided
- Volunteers
- 70 people
- Sponsor
- Kocaeli University
Atrial Fibrillation
PeAF-BOX: Feasibility, Safety and Efficacy of PVI + Box Ablation in Persistent Atrial Fibrillation
Title: PeAF-Box. Feasibility, Safety and Efficacy of Isolating the Left Atrial Posterior Wall (PWI) added to Pulmonary Vein Isolation (PVI) as First-Line Strategy in Treatment of Persistent Atrial Fibrillation (PeAF) Design: A…
- Trial name
- PeAF-BOX (NCT05045131)
- Testing
- Left atrial combined pulmonary vein isolation and posterior wall isolation
- Volunteers
- 24 people
- Sponsor
- René Husted Worck
Surgical Blood Loss, Postoperative Pain
PVI vs ESP Block for Reducing Bleeding and Postoperative Pain in Lumbar Fusion Surgery.
This randomized controlled trial compares periarticular vasoconstrictor infiltration (PVI) versus erector spinae plane block (ESP) to reduce bleeding and postoperative pain in adults undergoing lumbar fusion surgery (up to 3…
- Conditions
- Surgical Blood Loss, Postoperative Pain, Lumbar Spinal Fusion Surgery
- Trial name
- NCT07550114
- Testing
- Periarticular vasoconstrictor infiltration (PVI), Erector Spinae Block (ESP)
- Where
- 2 sites in Spain
- Volunteers
- 62 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Atrial Fibrillation
Renal Denervation + PVI vs PVI Alone for Persistent AF
Pulmonary vein isolation (PVI) is the cornerstone of ablation for atrial fibrillation (AF). Increased cardiac sympathetic stimulation can facilitate AF and reduction can be accomplished by renal artery denervation (RDN).
- Trial name
- ERADICATE-AF (NCT05116384)
- Testing
- catheter ablation, renal artery denervation
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Rochester
Peripheral Vascular Diseases
MRI Guided Management of Occlusive Peripheral Arterial Disease
The goal of this observational study is to identify which plaque lesions in patients with peripheral arterial disease are impenetrable and to determine which devices minimize vessel wall injury.
- Trial name
- NCT06782100
- Where
- United States
- Volunteers
- 175 people
- Sponsor
- The Methodist Hospital Research Institute
PVI
Effectiveness of Finger and Forehead Plethysmographic Variability Index Monitoring in Pediatric Patients
In pediatric surgical patients, the sensitivity of forehead and finger PVI monitoring was similar for the prediction of fluid responsiveness, whereas the specificity of forehead monitoring was higher.
- Trial name
- NCT04835610
- Testing
- pvi
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people
- Sponsor
- Marmara University
Elective Posterior Lumbar Spinal Fusion for Spinal Stenosis, Spondylolisthesis
Assessing the Diagnostic Accuracy of Corrected Flow Time (FTc) and Pleth Variability Index (PVI) as Predictors of Fluid Responsiveness in Patients in the Prone Position Using the Jackson Table
Appropriate fluid management is an important part of anesthesia in patients undergoing surgery, and several dynamic indices have been suggested to have high predictability for fluid responsiveness in patients receiving mechanical…
- Conditions
- Elective Posterior Lumbar Spinal Fusion for Spinal Stenosis, Spondylolisthesis, Spinal Fractures, Scoliosis or Tumors
- Trial name
- NCT02826889
- Testing
- Philips Intelivue MP70 monitor, Pleth Variability Index (PVI)
- Where
- South Korea
- Volunteers
- 58 people
- Sponsor
- Yonsei University
Paroxysmal Atrial Fibrillation, Atrial Fibrillation
Adjunctive Ganglionated Plexus Ablation in Redo-Pulmonary Vein Isolation
The investigator propose to test the efficacy of adjunctive ET-GP ablation in patients undergoing redo PVI for paroxysmal AF.
- Trial name
- ADD-GP (NCT03535818)
- Testing
- Radiofrequency ablation
- Where
- United Kingdom
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Surgery
Validation of Noninvasive Hemoglobin, Comparison of PVI to Standard Methods, and Validation of Clinical Efficacy of ORI
The study goal is to establish the correlation of hemoglobin values determined by the noninvasive pulse oximetry-determined hemoglobin (SpHb) system with hemoglobin as measured by other validated devices.
- Trial name
- NCT02841397
- Testing
- Masimo Pulse CO-Oximeter
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Masimo Corporation
Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation
PVI Using Cryoablation Alone in Paroxysmal AF Patients Converted From Persistent AF With Dofetilide
To determine the efficacy of cryoablation alone in patients with paroxysmal atrial fibrillation who have been pretreated with dofetilide and converted from persistent atrial fibrillation.
- Trial name
- ABLATE (NCT01877486)
- Testing
- Ablation
- Where
- United States
- Sponsor
- University of Rochester