Clinical trials: Pacing Therapy
Ventricular Tachycardia
Personalized Therapy Study - Intrinsic Antitachycardia Pacing Post-Approval Study (iATP PAS)
Medtronic is sponsoring the Intrinsic Antitachycardia Pacing Post-Approval Study (iATP PAS) to further confirm safety and effectiveness of ventricular iATP therapy in routine clinical practice, following commercial release of…
- Trial name
- NCT04496518
- Testing
- Intrinsic Antitachycardia Pacing (iATP) Therapy
- Where
- 92 sites in United States, France and 7 more
- Volunteers
- 2,200 people, healthy volunteers welcome
- Sponsor
- Medtronic
Heart Failure
Stem Cells and Resynchronization Cardiac
Same patients with dilated myocardiopathies with large areas of fibrosis has not been as successful after Cardiac Resynchronization Therapy, for Heart Failure patients in functional class III or IV.
- Trial name
- RCT and SCT (NCT00800657)
- Testing
- Pacing and Stem Cells Implantations., Pacing and Stem Cells Implantation
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Instituto de Molestias Cardiovasculares
Heart Failure
CT Guided WiSE-CRT
This feasibility study will use CT scanning to identify the optimal location for placement of the WiSE-CRT system.
- Trial name
- NCT03495505
- Testing
- WiSE-CRT
- Where
- United Kingdom
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Left Bundle-Branch Block, Right Bundle-Branch Block
Non-invasive Mapping Using Ultra-high Frequency Electrocardiography
Cardiac electrical mapping is an important tool that allows doctors to study the electrical activity of the heart in detail. Electrical mapping systems used in clinical practice are time consuming, invasive and very costly.
- Conditions
- Left Bundle-Branch Block, Right Bundle-Branch Block, Non-Specific Intraventricular Conduction Defect
- Trial name
- NCT04537455
- Testing
- Ultra-high frequency electrocardiography
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Cardiac Electrophysiology
Transvenous Lead Removal Post-Market Clinical Study
This prospective, multicenter, post-market clinical study was designed to evaluate the outcomes of lead extraction of cardiovascular implantable electronic devices (CIED) using Cook catheter and lead extraction devices for any…
- Trial name
- NCT03688412
- Testing
- Cook lead extraction devices
- Where
- 9 sites in United States, Germany and 2 more
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Cook Research Incorporated
Intracranial Aneurysm, Surgical Clip
Rapid Ventricular Pacing in Surgical Treatment of Intracranial Aneurysms
Treatment of complex unruptured intracranial aneurysms (UIA) remains challenging to date. Therefore, advanced techniques are required to achieve an optimal result in treating these patients safely.
- Trial name
- NCT02766972
- Testing
- Rapid Ventricular Pacing
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Clinic Frankfurt
Heart Failure
Biomarkers to Predict CRT Response in Patients With HF (BIOCRT)
The prospective study aims: 1. To determine the role and mechanism of biomarkers for prediction of response to CRT 2. To determine the role of biomarkers and their effect on left ventricular remodeling in patients undergoing CRT.
- Trial name
- BIOCRT (NCT01949246)
- Where
- United States
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Bradycardia, Left Bundle Branch Area Pacing
Left Bundle Branch Area Pacing (LBBAP) Monitoring Assistant: Evaluation of Portable ECG Solution
To evaluate the capability to monitor LBB success criteria with the use of a Smart ECG system (ECG monitor, 12 leads ECG cable, ECG viewer software ) during a cardiac device implantation involving the placement of a pacing lead…
- Conditions
- Bradycardia, Left Bundle Branch Area Pacing, Cardiac Resynchronisation Therapy (CRT), ECG
- Trial name
- LBBOT (NCT07254013)
- Testing
- LBBAP implant
- Where
- 4 sites in France
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- MicroPort CRM
Heart Failure
Triple-site Biventricular Stimulation in the Optimization of CRT
Cardiac resynchronization is a recommended therapy for patients with advanced heart failure, under optimized medical treatment with reduced left ventricular ejection fraction and prolonged QRS, nevertheless, still 30% of the…
- Trial name
- TRIUMPH-CRT (NCT02350842)
- Testing
- triple-site biventricular pacing with peri-operative echo guidance, standard biventricular pacing
- Where
- 14 sites in France, Germany and 4 more
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- MicroPort CRM