Clinical trials: Paediatric
Stem Cell Transplant, Stem Cell Transplantation
Fertility Protection for Children, Adolescents and Young Adults
This study focuses on improving fertility preservation and long-term care for children, adolescents, and young adults (CAYA) undergoing cancer treatments or stem cell transplantation.
- Conditions
- Stem Cell Transplant, Stem Cell Transplantation, Oncological Outcomes, Oncological Patients
- Trial name
- FeProCAYA (NCT06692868)
- Where
- Germany
- Volunteers
- 2,000 people
- Sponsor
- University of Ulm
Paediatric Surgery
Residual Torsional Deformity in Pediatric Genu Varum After Coronal Plane Deformity Correction by 8 Plate Hemi Epiphysiodesis.
This study is to evaluate the residual torsional deformity in pediatric Genu Varum after coronal plane deformity correction by 8 plate hemi epiphysiodesis.
- Trial name
- NCT05334862
- Testing
- 8 plate hemiepiphysiodesis
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Assiut University
Paediatric Patients
A Fast, Quiet, Artificial Intelligence-based PET/MR Solution for Paediatric Diseases
To investigate the feasibility of deep learning-assisted rapid silent PET/MR in pediatric applications.
- Trial name
- NCT06709690
- Where
- China
- Volunteers
- 35 people
- Sponsor
- Ruijin Hospital
ICU, Nutrition
Nutrition in Paediatric Critical Care
This is a multi-centre prospective cohort study of nutrition in paediatric critical care in Australia and New Zealand. The study is planned to run in parallel with the adult ICU cohort study, NUTRIENT.
- Conditions
- ICU, Nutrition, Paediatric
- Trial name
- ePICUre (NCT06695078)
- Testing
- No Intervention: Observational Cohort
- Where
- 11 sites in Australia, New Zealand
- Volunteers
- 200 people
- Sponsor
- Australian and New Zealand Intensive Care Research Centre
Virtual Reality, Paediatrics
Virtual Reality Preparation for Medical Imaging
This pilot project aims to establish evidence to investigate whether a virtual reality intervention can be implemented to reduce anxiety and efficiently prepare children for non-sedated MRI assessments.
- Conditions
- Virtual Reality, Paediatrics, Radiology
- Trial name
- VR-MRI (NCT03931382)
- Testing
- Virtual Reality Simulator, Mock MRI Simulator, Standard Preparation Manual
- Where
- Canada
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- British Columbia Children's Hospital
Paediatric Brain Damage, Cerebral Palsy
Transcranial Direct Current Stimulation and Gamified Rehabilitation for Upper Limb Function in Pediatric Brain Damage
The goal of this clinical trial is to acknowledge the effects of transcranial direct current stimulation as an adjuvant with gaming rehabilitation for upper limb function rehabilitation in paediatric population with…
- Conditions
- Paediatric Brain Damage, Cerebral Palsy, Paediatric Stroke, Paediatric Traumatic Brain Injury
- Trial name
- NCT06214364
- Testing
- Active Transcranial Direct Current Stimulation
- Where
- Spain
- Volunteers
- 36 people
- Sponsor
- Universidad Francisco de Vitoria
Hiv, HIV Infections
Long-Acting Treatment in Adolescents (LATA)
The LATA trial will find out if taking a long-acting injectable form of HIV medicines, called cabotegravir and rilpivirine, every 2 month works as well as taking tablet HIV medicines every day in young people aged 12-19 years of…
- Conditions
- Hiv, HIV Infections, HIV-1-infection, Paediatric Human Immunodeficiency Virus Infection
- Trial name
- LATA (NCT05154747)
- Testing
- Cabotegravir, Rilpivirine Drug Combination, TLD
- Where
- 5 sites in Kenya, South Africa and 2 more
- Volunteers
- 476 people
- Sponsor
- University College, London
Pre-operative Anxiety, Otoplasty
The Impact of an Animated Video on Preoperative Anxiety in Children Undergoing Elective Otoplasty
The study is a prospective, randomized, single-blind controlled superiority trial to evaluate the effect of viewing an informative animated video a day prior to surgery on preoperative anxiety in pediatric patients scheduled for…
- Conditions
- Pre-operative Anxiety, Otoplasty, Paediatric Surgery
- Trial name
- NCT05894187
- Testing
- animated video
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Malformation, Tumor
Computational Anatomy in Surgery for Childhood Tumours and Malformations
This study is part of the launch of a multidisciplinary project called IMAG2, for image-guided minimally invasive surgery. It involves collaboration between the radiology and surgery teams at Necker Hospital and the Image…
- Conditions
- Malformation, Tumor, Paediatric Surgery, 3D Imaging
- Trial name
- IMAG2 (NCT06224985)
- Where
- France
- Volunteers
- 131 people
- Sponsor
- Imagine Institute
Paediatric Palliative Care
Effectiveness of Specialised Paediatric Palliative Care
This study evaluates the effectiveness of an existing Specialised Paediatric Palliative Care programme and reports on its potential to improve patient-, family-, health professionals-, and healthcare-related outcomes.
- Trial name
- SPhAERA (NCT04236180)
- Testing
- Specialised Paediatric Palliative Care (SPPC)
- Where
- 4 sites in Switzerland
- Volunteers
- 70 people
- Sponsor
- University Children's Hospital, Zurich
Paediatrics, General Anaesthesia
Comparison of the Anaesthetic Gases in Maintainance of General Anaesthesia in Paediatrics
Desflurane and Sevoflurane are one of the modern inhalational anaesthetic agents currently in use in anaesthetic practice. The properties of desflurane that has low blood gas solubility coefficient of 0.47 compared to sevoflurane…
- Trial name
- NCT04771962
- Testing
- DESFLURANE AND SEVOFLURANE
- Where
- Malaysia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
LOW AND INTERMEDIATE PAEDIATRIC NEUROBLASTOMA AND NEONATAL SUPRARENAL MASSES
European Low and Intermediate Risk Neuroblastoma Protocol
The European study, LINES 2009 (Low and Intermediate Risk Neuroblastoma European Study), groups together in a single protocol the treatment of all patients with "non high risk" neuroblastoma (NB), with stratification into two…
- Trial name
- NCT01728155
- Testing
- chemotherapy
- Where
- 98 sites in Australia, Austria and 8 more
- Volunteers
- 685 people
- Sponsor
- Instituto de Investigacion Sanitaria La Fe
Postoperative Pain in Paediatric Hip Surgery, PENG Block
Ultrasound Guided Pericapsular Nerve Group Block Versus Ultrasound Guided Caudal Block for Postoperative Pain in Paediatric Hip Surgery
Aim of the study is to evaluate postoperative analgesic effect of ultrasound guided PENG block in comparison to ultrasound guided caudal epidural anaesthesia for hip surgeries in paediatrics
- Conditions
- Postoperative Pain in Paediatric Hip Surgery, PENG Block, Caudal Block
- Trial name
- NCT05981781
- Testing
- ultrasound guided peng block in paediatric hip surgery, ultrasound guided caudal epidural block in paediatric hip surgery
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Alexandria University
Paediatric Airway Management
Improvement of Laryngoscopic View by Bed-up-head-elevated Position During Tracheal Intubation in Paediatric Patients
The goal of this prospective observational study is to learn about improvement of laryngoscopic view by Bed-Up-Head-Elevated (BUHE) during tracheal intubation in paediatric patients. The main question it aims to answer is: 1.
- Trial name
- NCT05885789
- Testing
- Intubation in Bed-Up-Head-Elevated (BUHE) position
- Where
- Malaysia
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Paediatric Dentistry
Molar Incisor Malformation in Egypt
The aim of the current study is to assess the prevalence of molar incisor malformation in Fayoum-Egypt.
- Trial name
- NCT05848388
- Testing
- Molar incisor malformation presence
- Where
- Egypt
- Volunteers
- 5,630 people
- Sponsor
- Fayoum University
Virtual Reality, Physical Rehabilitation
Using Immersive Virtual Reality for Children's Lower Limb Rehabilitation
Patients who have undergone lower limb or knee surgery are often required to participate in rehabilitative exercises to regain or maximise movement and function in the affected leg.
- Conditions
- Virtual Reality, Physical Rehabilitation, Lower Limb Injury, Paediatric
- Trial name
- NCT05274152
- Testing
- Immersive Virtual Reality Lower Limb and Knee Rehabilitation
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- Sheffield Hallam University
Paediatric, Surgery
Erector Spinae Plane Block for Paediatric Upper Abdominal Surgery
Upper abdominal surgeries are associated with severe postoperative pain. Thus, maintaining effective postoperative analgesia in the paediatric age group is very crucial in terms of future pain perception and chronic pain…
- Conditions
- Paediatric, Surgery, Analgesia, Anesthesia
- Trial name
- NCT04518215
- Testing
- Erector Spinae Plain Block, Intra-Venous Analgesia
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Nazmy Edward Seif
Paediatric Cholesteatoma
Radical Mastoidectomy Versus Mastoid Oblitration in Pediatric Population
Chronic otitis media (COM) has a significant impact on health issues since prehistoric time. It is a global disease, seen in all the continents of world having different environmental and socioeconomic background.
- Trial name
- NCT05584891
- Testing
- mastoidectomy and mastoid oblitration
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Typically Developing Children, Talipes Equino Varus
Measuring Normal and Impaired Walking in Children Using the GAITRite Walkway
Walking measurement in children is important but there are challenges associated with obtaining reliable repeatable data in a clinical setting that is meaningful and easy to interpret.
- Conditions
- Typically Developing Children, Talipes Equino Varus, Paediatric Orthopaedic, Paediatric Neurological
- Trial name
- NCT05571501
- Testing
- Gait assessment using the GAITRIte walkway
- Where
- United Kingdom
- Volunteers
- 702 people, healthy volunteers welcome
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Access and Transport to Paediatric Intensive Care
Differences in Access to Emergency Paediatric Intensive Care and Care During Transport
There are fewer than 30 paediatric intensive care units (PICUs) in the United Kingdom (UK). This means that a critically ill child taken to their nearest hospital will need to be transferred to a PICU.
- Trial name
- DEPICT (NCT03520192)
- Where
- United Kingdom
- Volunteers
- 2,838 people
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust