Clinical trials: Pain, Chronic
Posttraumatic Stress Disorder, Traumatic Brain Injury
An Exploration of the Relationship Between Chronic Pain and Suicide Attempt Among Veterans
The purpose of this study is to explore the relationship between attempted and/or completed suicide and reported experience of chronic pain among an adult veteran population.
- Conditions
- Posttraumatic Stress Disorder, Traumatic Brain Injury, Suicide Attempt
- Trial name
- NCT01502436
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- VA Eastern Colorado Health Care System
Cancer
Ketamine Hydrochloride and Best Pain Management in Treating Cancer Patients With Neuropathic Pain
RATIONALE: Ketamine hydrochloride may lessen neuropathic pain in patients with cancer. It is not yet known whether ketamine hydrochloride given together with the best pain management is more effective than a placebo given…
- Trial name
- NCT01316744
- Testing
- ketamine hydrochloride, pharmacogenomic studies, questionnaire administration
- Where
- 3 sites in United Kingdom
- Volunteers
- 214 people
- Sponsor
- University of Glasgow
Chronic Pain
Non-Opioid Pramipexole and Pain
The long-term goal of this proposal is to identify non-opioid drugs that harness endogenous anti-inflammatory mechanisms resulting in the suppression of proinflammatory cytokines such as IL-1ß providing a novel approach to treat…
- Trial name
- NCT03842709
- Testing
- Pramipexole Oral Tablet
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of New Mexico
Cerival Pain, Chronic Neck Pain
Effects of Instrument-Assisted Soft Tissue Mobilization Versus Post Facilitation Stretch Technique in Chronic Neck Pain
Chronic neck pain is a prevalent musculoskeletal condition that commonly results in persistent pain, reduced cervical range of motion (ROM), functional disability, and decreased quality of life.
- Trial name
- NCT07887698
- Testing
- Instrument Assisted Soft Tissue Mobilization, Post Facilitation Stretch
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Foundation University Islamabad
Chronic Pain, Emotional Distress
ReActivate: Physiotherapist Led Intervention for A Adolescents and Young Adults With Musculoskelatal Pain
Recurrent or persistent musculoskeletal pain is an alarmingly common problem among adolescents, in Sweden as well as globally. Pain often co-occur with and psychological distress and have both been shown to be predictors of…
- Trial name
- NCT06410963
- Testing
- Reactivate
- Where
- Sweden
- Volunteers
- 35 people
- Sponsor
- Örebro University, Sweden
Alzheimer Disease
Clinical Analgesic Management in Dementia
This study is designed to assess the efficacy and safety of oxycodone in managing moderate to severe pain in patients with Alzheimer's disease.
- Trial name
- CALM-D (NCT07323914)
- Testing
- Tylex
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Xuanwu Hospital, Beijing
Chronic Low Back Pain (Non-specific, Uncomplicated)
Effect of Massage on Chronic Low Back Pain
This study will evaluate the effectiveness of two types of massage therapy for treating chronic low back pain.
- Trial name
- NCT00371384
- Testing
- massage
- Where
- United States
- Volunteers
- 399 people
- Sponsor
- Kaiser Permanente
Chronic Pain, Low Back Pain
Extended Reality-Assisted Therapy for Chronic Pain Management
The goal of this clinical trial is to test a home-based virtual reality rehabilitation application in patients with chronic low back pain.
- Trial name
- XR-PAIN (NCT06296433)
- Testing
- VR rehabilitation, VR video application
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Institut d'Investigacions Biomèdiques August Pi i Sunyer
Osteoarthritis
Safety and Efficacy of the Buprenorphine Transdermal Delivery System in Subjects With Osteoarthritis Pain.
The objective of this study is to assess the safety and efficacy of the buprenorphine transdermal system (5, 10, and 20 mg) in comparison to placebo transdermal system in subjects with osteoarthritis pain.
- Trial name
- NCT00314652
- Testing
- Buprenorphine transdermal delivery system
- Where
- 22 sites in United States
- Volunteers
- 260 people
- Sponsor
- Purdue Pharma LP
Insomnia Due to Medical Condition, Chronic Pain
Gabapentin and Tizanidine for Insomnia in Chronic Pain
This is a double-blind, placebo-controlled, randomized, crossover trial aimed at assessing the effect of gabapentin and tizanidine, two pain medications, on insomnia in chronic pain patients.
- Trial name
- NCT04429347
- Testing
- Gabapentin, Tizanidine
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of California, San Diego
Chronic Pelvic Pain Syndrome
Extracorporeal Shockwave and Myofascial Release Therapy in Chronic Pelvic Pain Syndrome
The primary aims of this research are three folds: (1) To identify more relatively effective interventions for improving pain symptoms in CP/CPPS patients.
- Trial name
- NCT05659199
- Testing
- extracorporeal shockwave, myofascial release
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Zongda Hospital affiliated to Southeast University
Chronic Pain, Acute Pain
Regional Anesthesia for Thyroidectomy
For more than 25 years, Regional Anesthesia has challenged anesthesiologists to determine whether it offers real benefits in terms of patient outcome from major surgery, compared with general anesthesia.
- Trial name
- NCT02108834
- Testing
- nerve block
- Where
- 2 sites in China
- Volunteers
- 79 people
- Sponsor
- Guangzhou First People's Hospital
Post Herpetic Neuralgia (PHN)
Transcutaneous Auricular Vagus Nerve Stimulation on Post-Herpetic Neuralgia
The purpose of this study is to evaluate the therapeutic efficacy of transcutaneous auricular vagus nerve stimulation (taVNS) in the treatment of patients with post-herpetic neuralgia (PHN).
- Trial name
- NCT07123987
- Testing
- transcutaneous auricular vagus nerve stimulation (taVNS), traditional medical treatment for PHN
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Mohamed Hosny Ismail Easa
Neck Pain
Masseter Thickness, Bruxism, and Oral Behaviors in Chronic Neck Pain
A total of 30 patients aged 18-65 years who present with chronic non-specific neck pain and 30 healthy volunteers will be included in the study.
- Trial name
- NCT06874816
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Beylikduzu State Hospital
Spinal Cord Injury, Chronic Pain
Association Between Types of Pain and Motor Activities Physical Activity
This study will investigate the relationships between: (1) physical activity (PA) and types of chronic pain (nociceptive and neuropathic), and (2) virtual reality (VR) and types of chronic pain (nociceptive and neuropathic).
- Trial name
- NCT05236933
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Temple University
Chronic Stable Angina Pectoris
Outcome Research to Confirm the Anti-anginal Effect of T89 in Patients With Stable Angina
This is a multi-center, double-blind, randomized, placebo-controlled, parallel-group phase 3 clinical study to confirm the safety and efficacy of T89 in patients with stable angina pectoris, with an extended open-label period to…
- Trial name
- NCT03789552
- Testing
- T89 capsule
- Where
- United States
- Volunteers
- 765 people
- Sponsor
- Tasly Pharmaceuticals, Inc.
Neck Pain
Effect of Sustained Natural Apophseal Glides and Myofascial Release on Chronic Non-specific Neck Pain
The aim of investigator's study is to combine and compare the two scientifically approved therapies for the CNSNP to investigate the short term and mid-term changes of the combination of these two manual techniques concerning…
- Trial name
- NCT05061121
- Testing
- combined effect
- Where
- Egypt
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Cairo University
Tennis Elbow
ITU Treatment for Chronic Epicondylitis Musculoskeletal Pain Reduction
This study evaluates the effectiveness, safety and patient tolerance for the use of Intense Therapeutic Ultrasound (ITU) for chronic, subcutaneous lateral Epicondylitis musculoskeletal tissue pain reduction began in July 2015 and…
- Trial name
- ITU (NCT03255733)
- Testing
- Intense Therapeutic Ultrasound Treatment
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Guided Therapy Systems
Spinal Surgery, Pain Intensity
Dexmedetomidine-esketamine Combination and Chronic Postsurgical Pain After Spinal Surgery
Spinal surgery is generally followed by severe postoperative pain, and poor pain control may cause adverse outcomes such as cardiovascular events, neurocognitive disorders, and chronic postsurgical pain (CPSP).
- Conditions
- Spinal Surgery, Pain Intensity, Dexmedetomidine, Esketamine
- Trial name
- NCT07525999
- Testing
- Combined dexmedetomidine-esketamine administration
- Where
- China
- Volunteers
- 274 people
- Sponsor
- Peking University First Hospital
Chronic Pain, Opioid Misuse
French Version of POMI Scale
French translation and validation of the Prescription Opioid Misuse Index scale (POMI), a brief questionnaire to assess opioid prescription misuse.
- Trial name
- POMI (NCT04979364)
- Volunteers
- 154 people
- Sponsor
- University Hospital, Clermont-Ferrand