Clinical trials: Pain, Chronic Disease
STEMI, NSTEMI
Prediction of Adverse Events From Non-PCI Coronary Plaques Using Machine Learning
The aim of our project is to predict, with the help of artificial intelligence (AI) and machine learning techniques, the natural history of non-flow-limiting coronary stenoses and to develop and validate a machine learning risk…
- Conditions
- STEMI, NSTEMI, Chronic Coranary Sindrome, Unstable Angina (UA)
- Trial name
- Predict AI (NCT07866144)
- Where
- Italy
- Volunteers
- 600 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Myofacial Pain, Pelvic Pain
Measuring Pelvic Floor Muscle Fitness Before and After Treatment
This study is being done to better understand and improve treatment for myofascial pelvic pain, a common cause of long-lasting pelvic pain in women.
- Conditions
- Myofacial Pain, Pelvic Pain, Myofascial Pelvic Pain, Chronic Pelvic Pain
- Trial name
- NCT07605598
- Testing
- Near Infrared Imaging
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of California, Los Angeles
Chronic Prostatitis With Chronic Pelvic Pain Syndrome
Chronic Prostatitis/Chronic Pelvic Pain Syndrome Patients
Chronic prostatitis/chronic pelvic pain syndrome (CPPS) is a common health problem among men and can cause severe quality of life.
- Trial name
- NCT06016595
- Testing
- Chronic prostatitis/chronic pelvic pain syndrome
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Hisar Intercontinental Hospital
Fibromyalgia, Chronic Pain
The Effects of CBT and tDCS on Fibromyalgia Patients
Investigators are seeking to determine the effects of CBT, anodal tDCS over left DLPFC, and combined CBT+ tDCS on clinical pain and functioning among a sample of patients with fibromyalgia.
- Trial name
- NCT02723175
- Testing
- Transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Medical University of South Carolina
Chronic Nociceptive Pain, Neuropathic Pain
A Pilot Study of Ultra Rapid Opioid Rotation and Titration of Oxymorphone
This project will explore the safety and feasibility of performing a successful intravenous patient controlled analgesia (IV PCA) Oxymorphone titration and conversion to oral ER Oxymorphone (extended release or OPANA ER) in the…
- Conditions
- Chronic Nociceptive Pain, Neuropathic Pain, Non-cancer Pain
- Trial name
- NCT00945919
- Testing
- Oxymorphone ER
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Osteoarthritis, Knee, Osteoarthritis, Hip
Open Label Safety and Tolerability Study of COV155 in Subjects With Osteoarthritis (OA) or Chronic Low Back Pain (CLBP)
A study to show the safety of COV155 in patients with osteoarthritis of the knee or hip or moderate to severe chronic low back pain.
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Hip, Chronic Low Back Pain
- Trial name
- NCT01722864
- Testing
- COV155
- Where
- 34 sites in United States
- Volunteers
- 153 people
- Sponsor
- Mallinckrodt
Back Pain, Low Back Pain
Tapentadol Prolonged Release (PR) Versus Oxycodone/Naloxone Prolonged Release in Severe Chronic Low Back Pain With a Neuropathic Component.
This was a clinical effectiveness trial designed to compare the effectiveness, safety, and tolerability of treatment with tapentadol prolonged release with that of oxycodone/naloxone prolonged release in non-opioid pre-treated…
- Conditions
- Back Pain, Low Back Pain, Neuropathic Pain
- Trial name
- NCT01838616
- Testing
- Tapentadol Prolonged Release, Oxycodone/Naloxone Prolonged Release
- Where
- 50 sites in Austria, Germany and 2 more
- Volunteers
- 367 people
- Sponsor
- Grünenthal GmbH
Shoulder Pain, Shoulder Impingement Syndrome
Micro-Fragmented Adipose Tissue (Lipogems®) Injection for Chronic Shoulder Pain in Persons With Spinal Cord Injury
Rotator cuff disease (i.e., rotator cuff tendinopathy or tear) is a common cause of shoulder pain in persons with chronic spinal cord injury (SCI).
- Conditions
- Shoulder Pain, Shoulder Impingement Syndrome, Rotator Cuff Impingement Syndrome, Rotator Cuff Tendinitis
- Trial name
- NCT03167138
- Testing
- Autologous micro-fragmented adipose tissue, Lipogems system
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Kessler Foundation
Fibromyalgia
Effectiveness of Video-based Multicomponent Treatment for Fibromyalgia Plus Face-to-face Sesions in Nature or at Sea
The aim of this study was to examine the effectiveness of a video-based multicomponent program: the Fibrowalk Virtual plus face-to-face sessions for patients with fibromyalgia (FM) in nature or at sea (FM) compared to Fibrowalk…
- Trial name
- NCT05395832
- Testing
- TAU + multicomponent treatment VIRTUAL FIBROWALK + 4 face-to-face sessions at sea, TAU + multicomponent treatment VIRTUAL FIBROWALK + 4 face-to-face sessions in nature, TAU + multicomponent treatment VIRTUAL FIBROWALK
- Where
- Spain
- Volunteers
- 109 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Spondyloarthropathy
Rehabilitative Therapy and Pridinol in Patients With Lumbar Spondylarthrosis and Chronic Low Back Pain
Spondyloarthrosis is a degenerative disease involving the intervertebral disc, vertebral bodies, and adjacent soft tissues. Treatment aims to slow disease progression and manage symptoms through an interdisciplinary approach.It…
- Trial name
- NCT06252064
- Testing
- Rehabilitation + Drug therapy, Rehabilitation, Drug therapy
- Where
- Italy
- Volunteers
- 86 people
- Sponsor
- University of Palermo
Pain
Evaluation of the Tolerability of Switching Subjects on Chronic ATC Opioid Therapy to Buprenorphine HCl Buccal Film
The primary aim of this study is to determine if chronic pain subjects on around-the-clock opioids who are receiving 100 to 220 mg oral morphine sulfate equivalent (MSE) can be safely transitioned on to buprenorphine…
- Trial name
- NCT01871285
- Testing
- Buprenorphine, Oxycodone, Morphine sulfate
- Where
- 3 sites in United States
- Volunteers
- 39 people
- Sponsor
- BioDelivery Sciences International
Coronary Artery Diseases
BIOTRONIK - BIOFLOW-III Registry French Satellite
For the majority of Coronary Artery Disease (CAD) treatment with Percutaneous Transluminal Coronary Angioplasty (PTCA) provides high initial procedure success.
- Trial name
- NCT02273648
- Testing
- Drug Eluting Stent (DES)
- Where
- 50 sites in France
- Volunteers
- 1,000 people
- Sponsor
- Biotronik France
Pain
Study to Evaluate the Efficacy and Safety of OraVescent Fentanyl Citrate Treatment for the Management of Breakthrough Pain in Opioid-Tolerant Patients With Noncancer-Related Chronic Pain
The purpose of the study is to evaluate the efficacy and safety of OraVescent fentanyl treatment compared to placebo treatment monthly over a 12-week treatment period in alleviating breakthrough pain (BTP) in opioid-tolerant…
- Trial name
- NCT00343733
- Testing
- OraVescent Fentanyl
- Where
- 21 sites in United States
- Volunteers
- 120 people
- Sponsor
- Cephalon
Musculoskeletal Disorder, Rotator Cuff Tendinitis
Body Schema Alterations in Musculoskeletal Disorders : Effect of Laterality
This study assess ocular movements in a hand laterality judgment task in a population of musculoskeletal disorders. Reaction time, error rate and visual strategy are compared between musculoskeletal disorders and healthy…
- Conditions
- Musculoskeletal Disorder, Rotator Cuff Tendinitis, Chronic Low Back Pain, Carpal Tunnel Syndrome
- Trial name
- Schem-TMS (NCT03567109)
- Testing
- hand laterality judgment task
- Where
- France
- Volunteers
- 71 people
- Sponsor
- University Hospital, Angers
Tonsillitis Chronic, Tonsillitis Recurrent
The Effect of Systemic Nonsteroidal Anti-inflammatory Drugs (NSAIDs) Vs Intraoperative Infiltration of Steroids in Tonsillar Bed Following Tonsillectomy on Post Tonsillectomy Pain.
The aim of this study is to compare the efficacy of adding paracetamol to systemic non-steroidal anti-inflammatory drugs (NSAIDs) versus adding dexamethasone as local infiltration to paracetamol on post tonsillectomy pain control.
- Conditions
- Tonsillitis Chronic, Tonsillitis Recurrent, OSA - Obstructive Sleep Apnea
- Trial name
- NSAIDs (NCT07035314)
- Testing
- Dexamethasone, NSAIDs, Control (Standard treatment)
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Ain Shams University
Pain
The Effect of Intravenous Lidocaine on Allodynia
The purpose of this study is to study if lidocaine, given intravenously, reduces pain.
- Trial name
- NCT00659633
- Testing
- lidocaine
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Alabama at Birmingham
Chronic Neck Pain, Disability
Association Between Neck Pain and Quality of Sleep
A prospective study to assess the association between the change in quality of sleep and the change in intensity of pain in Spanish patients seen for subacute or chronic neck pain.
- Trial name
- NCT00907049
- Where
- 2 sites in Spain
- Volunteers
- 424 people
- Sponsor
- Kovacs Foundation
Chronic Pain, Knee Pain Chronic
HFIT Versus TENS Study for Chronic Low Back and Knee Pain
A high-frequency impulse therapy (HFIT) device (Enso, San Francisco, CA) is a portable device for the treatment of musculoskeletal pain.
- Conditions
- Chronic Pain, Knee Pain Chronic, Back Pain, Low
- Trial name
- NCT05821530
- Testing
- HFIT, TENS, Control
- Where
- United States
- Volunteers
- 325 people
- Sponsor
- Hinge Health, Inc
Neuralgia, Peripheral Neuropathic Pain
Randomized Controlled Trial of Efficacy and Safety of Local Anesthetics and Steroids for Chronic Peripheral Post-traumatic Neuropathic Pain
The purpose of this study is to evaluate three different injectable solutions used to block ankle nerves to manage ankle pain. The current standard of medical care is to inject a combination of local anesthetics and steroids…
- Trial name
- RESPERIST (NCT03009500)
- Testing
- Bupivacaine, Depo-Medrol Injectable Product, Saline (Sodium Chloride) solution
- Where
- Canada
- Volunteers
- 3 people
- Sponsor
- University Health Network, Toronto
Cervical Pain, Lumbar Pain
EVALUATION OF THE TOLERABILITY AND BIOMEDICAL POTENTIAL OF A GARMENT CONTAINING PRINTED CERAMICS IN MUSCULAR PAIN
Today, a new revolution is underway in the textile industry with the introduction of new technologies that add special functions and properties to fabrics.
- Conditions
- Cervical Pain, Lumbar Pain, Muscular, Chronic Pain (Back / Neck)
- Trial name
- DZero (NCT07274293)
- Testing
- DZero
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- noiVita Srls
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