Clinical trials: Pain, Chronic Disease
Fibromyalgia, Chronic Widespread Pain
Comparison of Multidimensional Parameters in Women With Fibromyalgia and Healthy Controls
Fibromyalgia (FM) is a chronic, widespread pain syndrome affecting 2-6.6% of the population and significantly impairing quality of life.
- Trial name
- NCT07416097
- Testing
- Clinical and Questionnaire-Based Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University
Pelvic Pain, Levator Ani Syndrome
Photobiomodulation for Myofascial Pelvic Pain
The goal of this clinical trial is to evaluate the efficacy of photobiomodulation of the pelvic floor muscles in female Veterans with chronic pelvic pain.
- Conditions
- Pelvic Pain, Levator Ani Syndrome, Spastic Pelvic Floor Syndrome, Chronic Pelvic Pain Syndrome
- Trial name
- PMPP (NCT05926752)
- Testing
- SoLá therapy, Pelvic floor physical therapy
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Orlando VA Medical Center
Sciatica, Lumbar Disc Herniation
Electroacupuncture for Insomnia in Patients With Chronic Sciatica Due to Lumbar Disc Herniation: a Randomized Controlled Trial
The goal of this clinical trial is to learn if electroacupuncture can improve sleep in people with chronic sciatica caused by lumbar disc herniation. It will also assess the safety of this treatment.
- Conditions
- Sciatica, Lumbar Disc Herniation, Insomnia
- Trial name
- NCT07576348
- Testing
- Electroacupuncture
- Volunteers
- 114 people
- Sponsor
- Shanghai Yueyang Integrated Medicine Hospital
Sickle Cell Disease
High Dose Vitamin D for Sickle Cell Disease
Vitamin D deficiency (VDD) is very common among African American adolescents and adults in the US, ten times higher than is seen in Caucasians. VDD is also quite common in sickle cell disease (SCD).
- Trial name
- SCD-VitD (NCT01331148)
- Testing
- Vitamin D
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Wake Forest University Health Sciences
Chronic Pancreatitis, Chronic Pain
Pancreatic Quantitative Sensory Testing (P-QST)
Quantitative Sensory Testing (QST) is a novel investigative technique used in other pain conditions to evaluate patterns of chronic pain, and in this study will be used to elucidate pain patterns in patients with Chronic…
- Conditions
- Chronic Pancreatitis, Chronic Pain, Acute Recurrent Pancreatitis
- Trial name
- NCT06996535
- Testing
- Quantitative Sensory Test 1, Quantitative Sensory Test 2, Quantitative Sensory Test 3
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Fibromyalgia, Sleep
Efficacy and Safety of SR46349B in Patients With Sleep Disorders in Fibromyalgia
Fibromyalgics frequently report sleep disturbances, in particular poor and unrefreshing sleep. Additionally, studies have reported that sleep problems, pain and mood disturbances are associated in patients with fibromyalgia.
- Conditions
- Fibromyalgia, Sleep, Chronic Pain
- Trial name
- NCT00313885
- Testing
- eplivanserin (SR46349)
- Where
- 12 sites in United States, Canada
- Volunteers
- 205 people
- Sponsor
- Sanofi
Chronic Non-specific Low Back Pain
Effect of VR-MBCT in Chronic Nonspecific Low Back Pain
This is a multi-center, prospective, open-label randomized controlled trial evaluating the efficacy and safety of virtual reality-based mindfulness-based cognitive therapy (VR-MBCT) as an adjunct to usual care in adults with…
- Trial name
- VR-MBCT-CNLBP (NCT07589790)
- Testing
- Virtual Reality-Based Mindfulness Cognitive Therapy (VR-MBCT), Waitlist Usual Care Control Group
- Where
- China
- Volunteers
- 214 people
- Sponsor
- The First Affiliated Hospital of Soochow University
Neuralgia, Postherpetic, Diabetic Neuropathy
Neuropathic Pain Syndrome Patient Study (MK-0000-072)
The purpose of this study is to determine the best way to conduct clinical trials in patients with neuropathic pain (nerve pain). This study will see if generic pregabalin has any effect on neuropathic pain.
- Conditions
- Neuralgia, Postherpetic, Diabetic Neuropathy, Painful Small-Fiber Neuropathy, Idiopathic Distal Sensory Polyneuropathy
- Trial name
- NCT00570310
- Testing
- Comparator: pregabalin
- Volunteers
- 104 people
- Sponsor
- Merck Sharp & Dohme LLC
Coronary Artery Disease, Angina Pectoris
Ranolazine for Incomplete Vessel Revascularization Post-Percutaneous Coronary Intervention (PCI)
This study will evaluate the efficacy of ranolazine as compared with placebo when used as part of standard medical therapy in chronic angina subjects with incomplete revascularization post-percutaneous coronary intervention (PCI…
- Trial name
- RIVER-PCI (NCT01442038)
- Testing
- Ranolazine
- Where
- 218 sites in United States, Austria and 13 more
- Volunteers
- 2,651 people
- Sponsor
- Gilead Sciences
Fibromyalgia
Mechanisms of Affective Touch in Chronic Pain
This study compares how different types of touch found in massage therapies impact pain perception, and whether these effects differ in individuals with and without chronic pain.
- Trial name
- MATCP (NCT04206397)
- Testing
- affective touch
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Laura Case
Pain, Posttraumatic Stress Disorder
Integrated Treatment for Chronic Pain and Posttraumatic Stress Disorder (PTSD)
The purpose of this study is to examine the efficacy of an integrated treatment for Veterans with comorbid chronic pain and posttraumatic stress disorder (PTSD).
- Trial name
- NCT00127413
- Testing
- Cognitive Behavioral Therapy - Pain, Cognitive Behavioral Therapy-Integrated, Cognitive Processing Therapy - PTSD
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- US Department of Veterans Affairs
Osteoarthritis
Evolution of the State of Health of Patients Undergoing Surgery for Osteoarticular Surgery
Osteoarticular surgery is frequently associated with the occurrence of moderate to severe postoperative pain. This pain can persist and become chronic post-surgical pain that is often debilitating.
- Trial name
- EPOPEE (NCT05527860)
- Where
- France
- Volunteers
- 4,000 people
- Sponsor
- University Hospital, Strasbourg, France
Pain, Neuralgia, Postherpetic
A Study to Evaluate the Efficacy, Safety, and Tolerability of JNJ-42160443 in Patients With Neuropathic Pain (Postherpetic Neuralgia and Post-traumatic Neuralgia)
The purpose of this study is to evaluate the safety and effectiveness of JNJ-42160443 in the treatment of moderate to severe neuropathic pain in patients with a diagnosis of postherpetic neuralgia and post-traumatic neuralgia.
- Conditions
- Pain, Neuralgia, Postherpetic, Neuralgia, Mononeuropathies
- Trial name
- NCT00964990
- Testing
- JNJ-42160443
- Where
- 48 sites in United States, Belgium and 2 more
- Volunteers
- 112 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Pain, Trigeminal Neuralgia
Transcranial Magnetic Stimulation (TMS) Effects on Pain Perception
The purpose of this study is to investigate the effects of transcranial magnetic stimulation on pain perception.
- Conditions
- Pain, Trigeminal Neuralgia, Neuropathic Pain
- Trial name
- NCT00349050
- Testing
- laboratory pain assessment, transcranial magnetic stimulation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Sickle Cell Disease
Hybrid Effectiveness-Implementation Trial of Guided Relaxation and Acupuncture for Chronic Sickle Cell Disease Pain
The investigators will conduct a hybrid type 1 effectiveness implementation trial to assess the effectiveness of acupuncture and guided relaxation on 360 people with Sickle Cell Disease (SCD), while observing and gathering…
- Trial name
- GRACE (NCT04906447)
- Testing
- Guided Relaxation, Acupuncture
- Where
- 5 sites in United States
- Volunteers
- 379 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Low Back Pain, Obesity
The Effect of Traction Forces in People With Obesity Suffering From Chronic Low Back Pain
The purpose of the research study is to assess the impact of traction forces on changes in systemic markers concentrations of spinal structure damage in people with obesity.
- Trial name
- NCT04507074
- Testing
- lumbar traction therapy
- Where
- Poland
- Volunteers
- 49 people
- Sponsor
- Poznan University of Physical Education
Fibromyalgia
Self-regulation of Real-time fMRI Brain Activity in Chronic Pain
This study aims to explore the usefulness of self-regulation of brain activity in patients with fibromyalgia. Patients will use real-time functional magnetic resonance imaging (fMRI) neurofeedback to observe and regulate their…
- Trial name
- NCT07023523
- Testing
- Cognitive Behavioral Therapy, Disease Education
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Brigham and Women's Hospital
Complex Regional Pain Syndromes
Investigation of the Efficacy of Transcranial Magnetic Stimulation in Patients Developing Complex Regional Pain Syndrome Type 1 in the Upper Extremity During the Subacute-Chronic Period After Ischemic Stroke
The aim of our study is to investigate transcranial magnetic stimulation (TMS) as a treatment option in Complex Regional Pain Syndrome, disseminate it to a broader patient population, and simultaneously demonstrate its…
- Trial name
- NCT06215079
- Testing
- The Magstim Rapid2 Plus Magnetic Stimulator (Magstim, Whitland, Dyfed, UK), conventional rehabilitation program
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Ankara City Hospital Bilkent
Chronic Low Back Pain (CLBP), Lumbar Spondylosis
Efficacy of Electroacupuncture Combined With Auricular Acupressure for Chronic Low Back Pain.
Chronic low back pain (CLBP) due to lumbar spondylosis is a leading cause of disability, significantly impacting the quality of life in middle-aged and elderly populations.
- Trial name
- NCT07530042
- Testing
- Electroacupuncture, Auricular Acupressure
- Where
- Vietnam
- Volunteers
- 76 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Chronic Pain
Use of PET/MR Imaging in Chronic Pain
The investigators are studying the ability of PET/MR imaging (using the PET tracer [18F]FDG) to objectively identify and characterize pain generators in patients suffering from chronic pain.
- Trial name
- NCT03195270
- Testing
- [18F]FDG, PET/MRI
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Stanford University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.