Clinical trials: Pain, Chronic Disease
HIV Infections, Cancer
A Multicenter Phase II/III, Placebo-Controlled Study of SNX-111 Administered Intrathecally to Cancer and AIDS Patients With Chronic Pain
To determine the safety and efficacy of SNX-111 in controlling severe, chronic pain in cancer and AIDS patients.
- Conditions
- HIV Infections, Cancer, Pain
- Trial name
- NCT00002160
- Testing
- Ziconotide
- Where
- 44 sites in United States
- Volunteers
- 100 people
- Sponsor
- Neurex
Rheumatoid Arthritis
EMDR for Persistent Pain in RA
Rationale: Around 20% of rheumatoid arthritis (RA) patients have persistent pain, despite having well-controlled disease activity.
- Trial name
- NCT05941559
- Testing
- EMDR
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- Medisch Spectrum Twente
Pain and Metabolic Syndrome
The Prevalence of Metabolic Syndrome in Patients Suffering From Chronic Pain
Obesity is considered as the epidemic of the century. Central obesity is one of the metabolic syndrome's features. It has been proven that obesity can cause back pain and headaches; thus, there might be a link between chronic…
- Trial name
- NCT00885261
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Chronic Pain, Musculoskeletal Pain
Online Yoga vs Acceptance and Commitment Therapy for Treating Chronic Musculoskeletal Pain
This study will compare online yoga with Acceptance and Commitment Therapy (ACT), an established treatment for chronic pain. We will compare the efficacy of the two treatments for reducing chronic musculoskeletal pain in veterans.
- Trial name
- NCT06704061
- Testing
- Yoga, Acceptance and Commitment Therapy (ACT)
- Where
- United States
- Volunteers
- 274 people
- Sponsor
- Palo Alto Veterans Institute for Research
Inflammatory Bowel Diseases
Nabilone Use For Acute Pain in Inflammatory Bowel Disease Patients
This is a clinical trial of nabilone for patients with Inflammatory Bowel Disease (IBD) who are undergoing IBD-related surgery (Any abdominal surgery lasting for more than one hour).
- Trial name
- NCT03422861
- Testing
- Nabilone
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Migraine
An Open Label Extension of a Study of Topiramate in Chronic Migraine.
The purpose of this study is to assess the long-term safety and effectiveness of topiramate for the prevention of headaches in adults with chronic migraine. Topiramate has been approved to prevent migraine headaches.
- Trial name
- NCT00210873
- Testing
- topiramate
- Volunteers
- 200 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Knee Osteoarthritis; Insomnia; Cervical Spondylosis; Chronic Low Back Pain; Allergic Rhinitis
Validating Blinding Maintenance of a Sham-Sensitization Control Design for Sensitization Acupuncture Trials
This study is the clinical validation component of a broader research program developing a randomized controlled trial (RCT) comparing sensitization acupuncture (an individualized technique in which treatment points are selected…
- Trial name
- NCT07868224
- Testing
- Sensitization Acupuncture, Traditional Acupuncture
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Jiangxi University of Traditional Chinese Medicine
Pain, Chronic, Cancer Pain
Telemedicine Versus In-Person Follow-up for Cancer Pain Management: An Equity and Cost Analysis Comparison Using a Prospective Quasi-Experimental Design
Cancer is the second leading cause of death worldwide, with approximately 18.1 million new cases and 9.6 million deaths reported in 2018.
- Conditions
- Pain, Chronic, Cancer Pain, Cancer Related Pain
- Trial name
- NCT05628246
- Testing
- Telemedicine, In-person
- Where
- Thailand
- Volunteers
- 193 people
- Sponsor
- Mahidol University
Chronic Pain, Stroke
VR-ACT After Stroke: a Feasibility Study
This exploratory project aims to develop and pilot test, in a parallel group randomized controlled trial (RCT) design, the feasibility, acceptability, and preliminary efficacy of a self-management virtual reality (VR) 8-week…
- Trial name
- VR-ACT (NCT06990646)
- Testing
- VR-ACT
- Volunteers
- 30 people
- Sponsor
- University of Coimbra
Essential Hypertension, Chronic Stable Angina
Study to Compare the Pharmacokinetic Characteristics and Safety of Dilatrend SR Capsule 32mg and Dilatrend Tablet 25mg
The purpose of this study is to compare the pharmacokinetic characteristics and safety of dilatrend SR capsule 32mg and Dilatrend tablet 25mg in healthy male subjects.
- Conditions
- Essential Hypertension, Chronic Stable Angina, Congestive Heart Failure
- Trial name
- NCT01819870
- Testing
- Dilatrend SR capsule 32mg, Dilatrend IR tablet 25mg
- Where
- South Korea
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Chronic Pain, Recurrences
Comparison of Three Meshes in Lichtenstein Hernia Repair
Chronic pain may be a long-term problem after inguinal Lichtenstein hernioplasty. The aim of this study was to compare long-term results of hernioplasty using three different meshes (partly absorbable, lightweight polypropylene…
- Trial name
- Lichtenstein (NCT01295437)
- Testing
- Vypro II mesh, Premilene LP, Premilene mesh
- Where
- Finland
- Volunteers
- 300 people
- Sponsor
- Kuopio University Hospital
Lumbar Radiculopathy
Effect of Transfer of Energy Capacitive and Resistive on Chronic Discogenic Sciatica
The goal of this clinical trial is to evaluate the effect of Transfer of Energy Capacitive and Resistive (TECAR) on pain, functional disability and electrophysiological parameters in adults with chronic discogenic sciatica .
- Trial name
- NCT07841405
- Testing
- Transfer of Energy Capacitive and Resistive (TECAR) therapy, conventional physical therapy program
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Cairo University
PAIN, CHRONIC DISEASE
Evaluation of Pain Location, Pain Quality and Pain Patterns in Subjects With Chronic Pain
In earlier work, the Sponsor developed a computer image processing system for analysis of pain diagrams from patients with chronic pain.
- Trial name
- NCT00284245
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Taylor MicroTechnology
Pancreatitis
ESWL Versus ESWL and Endoscopic Treatment
The study wants to compare ESWL alone with ESWL and endoscopic drainage of the MPD for treatment of pain in chronic pancreatitis.
- Trial name
- NCT02971475
- Testing
- extracorporeal shock wave lithotripsy, endoscopic drainage of the main pancreatic duct, Analgesics
- Where
- 2 sites in China
- Volunteers
- 62 people
- Sponsor
- Changhai Hospital
Cerebral Palsy, Neurologic Disorder
Neural Mobilization and Cerebral Palsy
Objective: To assess the effect of neural mobilization applied to the lower limbs, compared to conventional physical therapy, in children diagnosed with Cerebral Palsy.
- Trial name
- NEUROREHAB (NCT06485830)
- Testing
- Neural mobilization of the lower limb, Conventional physical therapy
- Where
- 2 sites in Spain
- Volunteers
- 40 people
- Sponsor
- University of Seville
Fibromyalgia, Pain
Pain Relief Investigation of Neuromodulation Therapy in an Adult Fibromyalgia Population
This study is being performed to determine the safety and efficacy of Fralex Neuromodulation Therapy (F-NMT), delivered by the Fralex PRIMA device, in reducing chronic musculoskeletal pain associated with Fibromyalgia.
- Trial name
- NCT00450905
- Testing
- PRIMA Device
- Where
- 21 sites in United States, Canada
- Volunteers
- 200 people
- Sponsor
- Fralex Therapeutics
Chronic Regional Pain Syndrome
Interest of Day Hospital Care for Patients With Chronic Regional Pain Syndrome Referred to the Chronic Pain Unit for the First Time
Chronic Regional Pain Syndrome (CRPS) is a chronic disabling disease. Patients present a variable picture associating pain localized to an articular or peri-articular region, motor and vasomotor disorders and trophic disorders.
- Trial name
- NCT04913051
- Where
- France
- Volunteers
- 36 people
- Sponsor
- Centre Hospitalier le Mans
Rheumatoid Arthritis, Quality of Life
Music Therapy Model "The Bonny Method of Guided Imagery and Music" on Patients With Rheumatoid Arthritis
The aim of this study is to investigate the effect of music therapy and in particular of the model "The Bonny Method of Guided Imagery and Music (GIM)" in patients with rheumatoid arthritis (RA) in relation to both chronic pain…
- Conditions
- Rheumatoid Arthritis, Quality of Life, Chronic Pain
- Trial name
- GIM (NCT04380129)
- Testing
- Music therapy-conversation sessions, Music Listening
- Where
- Greece
- Volunteers
- 74 people
- Sponsor
- University of Thessaly
Endometriosis
Deep Neural Network Stratification for Use Detecting Endometriosis in Women Affected by Chronic Pelvic Pain (EndoCheck)
The goal of this observational study is to determine the clinical validity of a deep neural network algorithm that utilizes protein biomarker detection of Endometriosis - "EndoCheck" - as an "aid in diagnosis" for endometriosis…
- Trial name
- NCT05245695
- Testing
- Observational study, no intervention
- Where
- 10 sites in United States
- Volunteers
- 1,200 people
- Sponsor
- Aspira Women's Health
Knee Pain Chronic, Knee Osteoarthritis
Prevention, Management and Rehabilitation of Knee Osteoarthritis at the Workplace
The goal of this intervention study is to assess the effect of blood flow restricted (BFR) exercise integrated into the daily work tasks among hospital workers with or at increased risk of chronic knee pain.
- Conditions
- Knee Pain Chronic, Knee Osteoarthritis, Knee Discomfort
- Trial name
- NCT05822401
- Testing
- Blood flow restriction (BFR), Usual care (control)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Research Centre for the Working Environment, Denmark
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